| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q15678 | 1187 | PTN14_HUMAN Tyrosine-protein phosphatase non-... | 90 | 0.0002 | 48.1 | 38 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.::GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB. | | | | | | | | | | GO:0001946; P:lymphangiogenesis; IMP:UniProtKB. | 32 | Q05209 | 780 | PTN12_HUMAN Tyrosine-protein phosphatase non-... | 140 | 0.00000005 | 59.7 | 35 | 49 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0002102; C:podosome; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; TAS:ProtInc. | | | | | | | | | | GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc.::GO:0017124; F:SH3 domain binding; IPI:UniProtKB. | | | | | | | | | | | 33 | Q9IBD8 | 1216 | PTPRC_CYPCA Receptor-type tyrosine-protein ph... | 97 | 0.037 | 40.8 | 34 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0050852; P:T cell receptor signaling pathway; IEA:InterPro. | 34 | Q64512 | 2453 | PTN13_MOUSE Tyrosine-protein phosphatase non-... | 96 | 0.000002 | 55.1 | 40 | 54 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB. | | | | | | | | | | | 35 | P29352 | 802 | PTN22_MOUSE Tyrosine-protein phosphatase non-... | 107 | 0.014 | 42.4 | 33 | 45 | GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:BHF-UCL. | | | | | | | | | | GO:0019900; F:kinase binding; IPI:BHF-UCL.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL. | | | | | | | | | | GO:0050868; P:negative regulation of T cell activation; IMP:BHF-UCL.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; ISS:UniProtKB.::GO:0035644; P:phosphoanandamide dephosphorylation; IDA:BHF-UCL.::GO:0032817; P:regulation of natural killer cell proliferation; ISS:BHF-UCL.::GO:0030217; P:T cell differentiation; IMP:MGI.::GO:0050852; P:T cell receptor signaling pathway; IMP:MGI. | 36 | Q62656 | 2316 | PTPRZ_RAT Receptor-type tyrosine-protein phos... | 66 | 0.001 | 46.2 | 39 | 55 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 37 | Q4JDL3 | 420 | PTN20_HUMAN Tyrosine-protein phosphatase non-... | 148 | 0.0000000005 | 65.5 | 33 | 51 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 38 | P29350 | 595 | PTN6_HUMAN Tyrosine-protein phosphatase non-r... | 146 | 0.0000009 | 55.5 | 30 | 44 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; TAS:ProtInc.::GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:ProtInc.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0030154; P:cell differentiation; IDA:UniProtKB.::GO:0008283; P:cell proliferation; IDA:UniProtKB.::GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.::GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; IMP:BHF-UCL.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IMP:BHF-UCL.::GO:0070372; P:regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.::GO:2000045; P:regulation of G1/S transition of mitotic cell cycle; IMP:BHF-UCL.::GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0060337; P:type I interferon-mediated signaling pathway; TAS:Reactome. | 39 | Q16825 | 1174 | PTN21_HUMAN Tyrosine-protein phosphatase non-... | 95 | 0.0000002 | 57.8 | 42 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; TAS:ProtInc. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | | 40 | P32587 | 303 | PYP3_SCHPO Tyrosine-protein phosphatase 3 OS=... | 94 | 0.0000000004 | 64.7 | 39 | 55 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IDA:PomBase. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0007165; P:signal transduction; IC:PomBase. | 41 | P23471 | 2315 | PTPRZ_HUMAN Receptor-type tyrosine-protein ph... | 66 | 0.001 | 45.8 | 39 | 55 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0008330; F:protein tyrosine/threonine phosphatase activity; NAS:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | GO:0007417; P:central nervous system development; TAS:ProtInc. | 42 | Q62130 | 1189 | PTN14_MOUSE Tyrosine-protein phosphatase non-... | 90 | 0.0002 | 48.1 | 38 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0001946; P:lymphangiogenesis; IMP:UniProtKB. | 43 | P29351 | 595 | PTN6_MOUSE Tyrosine-protein phosphatase non-r... | 98 | 0.000006 | 52.8 | 35 | 51 | GO:0042105; C:alpha-beta T cell receptor complex; IDA:MGI.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0001784; F:phosphotyrosine binding; IPI:MGI.::GO:0042169; F:SH2 domain binding; IDA:MGI.::GO:0017124; F:SH3 domain binding; IDA:MGI.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050853; P:B cell receptor signaling pathway; IMP:MGI.::GO:0030154; P:cell differentiation; ISS:UniProtKB.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0019221; P:cytokine-mediated signaling pathway; TAS:MGI.::GO:0035556; P:intracellular signal transduction; IDA:MGI.::GO:0042267; P:natural killer cell mediated cytotoxicity; IMP:MGI.::GO:0002924; P:negative regulation of humoral immune response mediated by circulating immunoglobulin; IMP:MGI.::GO:0043407; P:negative regulation of MAP kinase activity; IMP:MGI.::GO:0043409; P:negative regulation of MAPK cascade; IMP:MGI.::GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.::GO:0042130; P:negative regulation of T cell proliferation; IMP:MGI.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IMP:MGI.::GO:0045577; P:regulation of B cell differentiation; IMP:MGI.::GO:0070372; P:regulation of ERK1 and ERK2 cascade; ISS:UniProtKB. | 44 | Q64605 | 1907 | PTPRS_RAT Receptor-type tyrosine-protein phos... | 98 | 0.000009 | 52.8 | 41 | 53 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IDA:RGD.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 45 | P81718 | 613 | PTN6_RAT Tyrosine-protein phosphatase non-rec... | 98 | 0.000005 | 53.1 | 35 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046703; F:natural killer cell lectin-like receptor binding; IPI:RGD.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; ISS:UniProtKB. | | | | | | | | | | GO:0030154; P:cell differentiation; ISS:UniProtKB.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0070372; P:regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0009611; P:response to wounding; IEP:RGD. | 46 | P35832 | 1301 | PTP99_DROME Tyrosine-protein phosphatase 99A ... | 99 | 0.000002 | 54.7 | 34 | 55 | GO:0030424; C:axon; IDA:FlyBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; ISS:FlyBase. | | | | | | | | | | GO:0007415; P:defasciculation of motor neuron axon; IGI:FlyBase.::GO:0008045; P:motor axon guidance; IGI:FlyBase. | 47 | Q8ISC9 | 555 | CSW_DROSI Tyrosine-protein phosphatase corksc... | 97 | 1.4 | 35.4 | 30 | 46 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0007362; P:terminal region determination; ISS:UniProtKB.::GO:0008293; P:torso signaling pathway; ISS:UniProtKB. | 48 | Q12923 | 2485 | PTN13_HUMAN Tyrosine-protein phosphatase non-... | 96 | 0.000002 | 55.1 | 40 | 53 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB. | | | | | | | | | | | 49 | P23470 | 1445 | PTPRG_HUMAN Receptor-type tyrosine-protein ph... | 67 | 0.096 | 39.7 | 34 | 51 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0042802; F:identical protein binding; IPI:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc. | 50 | Q62136 | 1176 | PTN21_MOUSE Tyrosine-protein phosphatase non-... | 95 | 0.0000001 | 58.5 | 42 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 51 | P10586 | 1907 | PTPRF_HUMAN Receptor-type tyrosine-protein ph... | 142 | 0.000003 | 53.9 | 35 | 48 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; TAS:ProtInc. | 52 | P23469 | 700 | PTPRE_HUMAN Receptor-type tyrosine-protein ph... | 150 | 0.00000008 | 58.9 | 28 | 43 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0006468; P:protein phosphorylation; IEA:InterPro. | 53 | B0V2N1 | 1907 | PTPRS_MOUSE Receptor-type tyrosine-protein ph... | 98 | 0.00001 | 52.4 | 41 | 53 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0021549; P:cerebellum development; IMP:MGI.::GO:0021987; P:cerebral cortex development; IMP:MGI.::GO:0022038; P:corpus callosum development; IMP:MGI.::GO:0021766; P:hippocampus development; IMP:MGI.::GO:0021510; P:spinal cord development; IMP:MGI. | 54 | P23468 | 1912 | PTPRD_HUMAN Receptor-type tyrosine-protein ph... | 142 | 0.0006 | 47 | 33 | 48 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; TAS:ProtInc. | 55 | Q64487 | 1912 | PTPRD_MOUSE Receptor-type tyrosine-protein ph... | 142 | 0.0006 | 47 | 33 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 56 | Q62728 | 1175 | PTN21_RAT Tyrosine-protein phosphatase non-re... | 95 | 0.0000001 | 58.5 | 42 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:RGD. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; NAS:RGD. | 57 | P29349 | 845 | CSW_DROME Tyrosine-protein phosphatase corksc... | 97 | 1.1 | 36.2 | 31 | 48 | GO:0005737; C:cytoplasm; NAS:UniProtKB. | | | | | | | | | | GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:FlyBase.::GO:0004728; F:receptor signaling protein tyrosine phosphatase activity; NAS:FlyBase. | | | | | | | | | | GO:0008069; P:dorsal/ventral axis specification, ovarian follicular epithelium; IMP:FlyBase.::GO:0007173; P:epidermal growth factor receptor signaling pathway; IMP:FlyBase.::GO:0007427; P:epithelial cell migration, open tracheal system; IMP:FlyBase.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; IMP:FlyBase.::GO:0007444; P:imaginal disc development; IMP:FlyBase.::GO:0007498; P:mesoderm development; IMP:FlyBase.::GO:0000278; P:mitotic cell cycle; IMP:FlyBase.::GO:0007428; P:primary branching, open tracheal system; TAS:FlyBase.::GO:0045314; P:regulation of compound eye photoreceptor development; IMP:FlyBase.::GO:0045500; P:sevenless signaling pathway; TAS:FlyBase.::GO:0007362; P:terminal region determination; IMP:UniProtKB.::GO:0008293; P:torso signaling pathway; IGI:UniProtKB.::GO:0007418; P:ventral midline development; IMP:FlyBase. | 58 | O13016 | 434 | PTN1_CHICK Tyrosine-protein phosphatase non-r... | 70 | 0.00000006 | 58.9 | 44 | 57 | GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:UniProtKB.::GO:0030100; P:regulation of endocytosis; ISS:UniProtKB.::GO:0009966; P:regulation of signal transduction; ISS:UniProtKB. | 59 | A2A8L5 | 1898 | PTPRF_MOUSE Receptor-type tyrosine-protein ph... | 161 | 0.000004 | 53.9 | 34 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 60 | A2ALK8 | 913 | PTN3_MOUSE Tyrosine-protein phosphatase non-r... | 124 | 0.000000006 | 62.8 | 35 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB. | | | | | | | | | | | 61 | Q98936 | 1422 | PTPRG_CHICK Receptor-type tyrosine-protein ph... | 67 | 0.023 | 41.6 | 36 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | |
