| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | Q924T7 | 1066 | RNF31_MOUSE E3 ubiquitin-protein ligase RNF31... | 226 | 0.000003 | 53.9 | 25 | 39 | GO:0035631; C:CD40 receptor complex; IDA:BHF-UCL.::GO:0005829; C:cytosol; IDA:MGI.::GO:0009898; C:internal side of plasma membrane; IDA:BHF-UCL.::GO:0071797; C:LUBAC complex; ISS:UniProtKB. | | | | | | | | | | GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0023035; P:CD40 signaling pathway; IMP:BHF-UCL.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0097039; P:protein linear polyubiquitination; ISS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB. | 62 | Q9WVS6 | 464 | PRKN2_MOUSE E3 ubiquitin-protein ligase parki... | 67 | 0.000003 | 53.1 | 42 | 54 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0043234; C:protein complex; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008344; P:adult locomotory behavior; IMP:MGI.::GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0042417; P:dopamine metabolic process; IMP:MGI.::GO:0051583; P:dopamine uptake; IMP:MGI.::GO:0007612; P:learning; IMP:MGI.::GO:0070997; P:neuron death; ISS:UniProtKB.::GO:0042415; P:norepinephrine metabolic process; IMP:MGI.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0010506; P:regulation of autophagy; ISS:UniProtKB.::GO:0046928; P:regulation of neurotransmitter secretion; IMP:MGI.::GO:0001964; P:startle response; IMP:MGI.::GO:0035249; P:synaptic transmission, glutamatergic; IMP:MGI.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB. | 63 | Q9JK66 | 465 | PRKN2_RAT E3 ubiquitin-protein ligase parkin ... | 67 | 0.000003 | 53.1 | 42 | 54 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IDA:RGD.::GO:0000139; C:Golgi membrane; IDA:RGD.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IDA:RGD.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0008021; C:synaptic vesicle; IDA:RGD. | | | | | | | | | | GO:0032403; F:protein complex binding; IDA:RGD.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0070997; P:neuron death; ISS:UniProtKB.::GO:0042551; P:neuron maturation; IEP:RGD.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0010506; P:regulation of autophagy; ISS:UniProtKB.::GO:0051412; P:response to corticosterone stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0006986; P:response to unfolded protein; IDA:RGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB. | 64 | Q5UQ35 | 990 | YR811_MIMIV Putative ariadne-like RING finger... | 74 | 0.000005 | 53.1 | 36 | 51 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 65 | O60260 | 465 | PRKN2_HUMAN E3 ubiquitin-protein ligase parki... | 67 | 0.00001 | 51.6 | 40 | 54 | GO:0016235; C:aggresome; IDA:BHF-UCL.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0051087; F:chaperone binding; IPI:BHF-UCL.::GO:0030165; F:PDZ domain binding; IPI:BHF-UCL.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070842; P:aggresome assembly; IMP:BHF-UCL.::GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0000422; P:mitochondrion degradation; IMP:UniProtKB.::GO:0032232; P:negative regulation of actin filament bundle assembly; IDA:BHF-UCL.::GO:0060548; P:negative regulation of cell death; IDA:BHF-UCL.::GO:0001933; P:negative regulation of protein phosphorylation; IDA:BHF-UCL.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IDA:BHF-UCL.::GO:0070997; P:neuron death; IDA:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IDA:BHF-UCL.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0006513; P:protein monoubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0010506; P:regulation of autophagy; IDA:UniProtKB.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:UniProtKB. | 66 | Q04638 | 464 | ITT1_YEAST Translation termination inhibitor ... | 327 | 0.0003 | 47 | 25 | 38 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006449; P:regulation of translational termination; IMP:SGD. | 67 | E6ZIJ1 | 707 | HOIL1_DICLA RanBP-type and C3HC4-type zinc fi... | 228 | 0.014 | 42 | 24 | 35 | GO:0071797; C:LUBAC complex; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0097039; P:protein linear polyubiquitination; ISS:UniProtKB. | 68 | A9JTG5 | 714 | HOIL1_DANRE RanBP-type and C3HC4-type zinc fi... | 228 | 0.047 | 40 | 23 | 34 | GO:0071797; C:LUBAC complex; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0048701; P:embryonic cranial skeleton morphogenesis; IMP:ZFIN.::GO:0071600; P:otic vesicle morphogenesis; IMP:ZFIN.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0097039; P:protein linear polyubiquitination; ISS:UniProtKB. | 69 | Q6GZQ2 | 324 | 073L_FRG3G Uncharacterized protein 073L OS=Fr... | 42 | 0.1 | 38.5 | 40 | 57 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 70 | Q9BYM8 | 510 | HOIL1_HUMAN RanBP-type and C3HC4-type zinc fi... | 192 | 0.38 | 37 | 23 | 40 | GO:0071797; C:LUBAC complex; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043130; F:ubiquitin binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0097039; P:protein linear polyubiquitination; IDA:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IDA:UniProtKB. | 71 | Q60A06 | 1358 | RPOB_METCA DNA-directed RNA polymerase subuni... | 90 | 0.46 | 37 | 29 | 49 | | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0032549; F:ribonucleoside binding; IEA:InterPro. | | | | | | | | | | | 72 | Q9WUB0 | 508 | HOIL1_MOUSE RanBP-type and C3HC4-type zinc fi... | 190 | 0.68 | 36.2 | 24 | 41 | GO:0071797; C:LUBAC complex; ISS:UniProtKB. | | | | | | | | | | GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IMP:UniProtKB.::GO:0097039; P:protein linear polyubiquitination; ISS:UniProtKB. | 73 | Q9NWF9 | 866 | RN216_HUMAN E3 ubiquitin-protein ligase RNF21... | 36 | 1.1 | 35.8 | 39 | 67 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0050691; P:regulation of defense response to virus by host; IDA:UniProtKB.::GO:0032648; P:regulation of interferon-beta production; IDA:UniProtKB. | 74 | P58283 | 853 | RN216_MOUSE E3 ubiquitin-protein ligase RNF21... | 36 | 1.1 | 35.8 | 39 | 67 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0050691; P:regulation of defense response to virus by host; ISS:UniProtKB.::GO:0032648; P:regulation of interferon-beta production; ISS:UniProtKB. | 75 | Q62921 | 508 | HOIL1_RAT RanBP-type and C3HC4-type zinc fing... | 190 | 1.2 | 35.4 | 24 | 40 | GO:0071797; C:LUBAC complex; ISS:UniProtKB. | | | | | | | | | | GO:0003690; F:double-stranded DNA binding; IDA:RGD.::GO:0005080; F:protein kinase C binding; IPI:RGD.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:RGD.::GO:0097039; P:protein linear polyubiquitination; ISS:UniProtKB. | 76 | Q1LV17 | 605 | I2BP1_DANRE Interferon regulatory factor 2-bi... | 53 | 1.6 | 35 | 34 | 51 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 77 | Q8R3Y8 | 584 | I2BP1_MOUSE Interferon regulatory factor 2-bi... | 53 | 3.4 | 34.3 | 32 | 53 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 78 | Q8IU81 | 584 | I2BP1_HUMAN Interferon regulatory factor 2-bi... | 53 | 3.8 | 33.9 | 32 | 53 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 79 | E1B7X3 | 346 | R146A_BOVIN E3 ubiquitin-protein ligase RNF14... | 151 | 6.1 | 33.1 | 24 | 40 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | GO:0072572; F:poly-ADP-D-ribose binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 80 | Q9NPI8 | 374 | FANCF_HUMAN Fanconi anemia group F protein OS... | 115 | 6.2 | 33.1 | 33 | 46 | GO:0043240; C:Fanconi anaemia nuclear complex; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006281; P:DNA repair; TAS:Reactome. | 81 | Q8CEF8 | 211 | RN222_MOUSE RING finger protein 222 OS=Mus mu... | 50 | 7.4 | 32.3 | 38 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | |
