rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q12200 | 1170 | NPC1_YEAST Niemann-Pick type C-related protei... | 1242 | 0 | 880 | 42 | 59 | GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008158; F:hedgehog receptor activity; IEA:InterPro.::GO:0046624; F:sphingolipid transporter activity; IMP:SGD. | | | | | | | | | | GO:0006665; P:sphingolipid metabolic process; IMP:SGD. | 2 | O35604 | 1278 | NPC1_MOUSE Niemann-Pick C1 protein OS=Mus mus... | 1311 | 0 | 672 | 34 | 52 | GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.::GO:0005635; C:nuclear envelope; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0008158; F:hedgehog receptor activity; IEA:InterPro. | | | | | | | | | | GO:0008206; P:bile acid metabolic process; ISS:UniProtKB.::GO:0042632; P:cholesterol homeostasis; ISS:UniProtKB.::GO:0030301; P:cholesterol transport; IEA:InterPro.::GO:0007041; P:lysosomal transport; ISS:UniProtKB. | 3 | P56941 | 1277 | NPC1_PIG Niemann-Pick C1 protein OS=Sus scrof... | 1311 | 0 | 667 | 34 | 51 | GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.::GO:0005635; C:nuclear envelope; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0008158; F:hedgehog receptor activity; IEA:InterPro. | | | | | | | | | | GO:0008206; P:bile acid metabolic process; ISS:UniProtKB.::GO:0042632; P:cholesterol homeostasis; ISS:UniProtKB.::GO:0030301; P:cholesterol transport; IEA:InterPro.::GO:0007041; P:lysosomal transport; ISS:UniProtKB. | 4 | O15118 | 1278 | NPC1_HUMAN Niemann-Pick C1 protein OS=Homo sa... | 1315 | 0 | 664 | 33 | 51 | GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.::GO:0005635; C:nuclear envelope; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0008158; F:hedgehog receptor activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0015248; F:sterol transporter activity; TAS:ProtInc. | | | | | | | | | | GO:0006914; P:autophagy; IGI:MGI.::GO:0008206; P:bile acid metabolic process; ISS:UniProtKB.::GO:0033344; P:cholesterol efflux; IDA:BHF-UCL.::GO:0042632; P:cholesterol homeostasis; IDA:UniProtKB.::GO:0007041; P:lysosomal transport; ISS:UniProtKB. | 5 | Q6T3U3 | 1331 | NPCL1_RAT Niemann-Pick C1-like protein 1 OS=R... | 1321 | 0 | 614 | 32 | 49 | GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0031526; C:brush border membrane; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008144; F:drug binding; IDA:RGD.::GO:0008158; F:hedgehog receptor activity; IEA:InterPro. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0030301; P:cholesterol transport; IEA:InterPro.::GO:0042493; P:response to drug; IEP:RGD. | 6 | Q9UHC9 | 1359 | NPCL1_HUMAN Niemann-Pick C1-like protein 1 OS... | 1339 | 0 | 580 | 32 | 50 | GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IDA:UniProtKB. | | | | | | | | | | GO:0008158; F:hedgehog receptor activity; IEA:InterPro.::GO:0031489; F:myosin V binding; IPI:UniProtKB.::GO:0017137; F:Rab GTPase binding; IPI:UniProtKB. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IMP:HGNC.::GO:0030299; P:intestinal cholesterol absorption; IMP:HGNC.::GO:0042157; P:lipoprotein metabolic process; IMP:HGNC. | 7 | Q6T3U4 | 1333 | NPCL1_MOUSE Niemann-Pick C1-like protein 1 OS... | 1351 | 4e-174 | 559 | 32 | 49 | GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008158; F:hedgehog receptor activity; IEA:InterPro. | | | | | | | | | | GO:0042632; P:cholesterol homeostasis; IMP:MGI. | 8 | Q19127 | 1383 | NPC1_CAEEL Niemann-Pick C1 protein homolog 1 ... | 1342 | 2e-111 | 387 | 26 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008158; F:hedgehog receptor activity; IEA:InterPro. | | | | | | | | | | GO:0042632; P:cholesterol homeostasis; IMP:WormBase.::GO:0030301; P:cholesterol transport; IMP:WormBase.::GO:0040024; P:dauer larval development; IGI:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0046662; P:regulation of oviposition; IMP:WormBase. | 9 | P34389 | 1274 | NPC2_CAEEL Niemann-Pick C1 protein homolog 2 ... | 1236 | 3e-78 | 286 | 24 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008158; F:hedgehog receptor activity; IEA:InterPro. | | | | | | | | | | GO:0042632; P:cholesterol homeostasis; IGI:WormBase.::GO:0030301; P:cholesterol transport; IGI:WormBase.::GO:0040024; P:dauer larval development; IGI:WormBase.::GO:0040025; P:vulval development; IGI:WormBase. | 10 | Q0EEE2 | 906 | PTHD3_MOUSE Patched domain-containing protein... | 923 | 5e-41 | 167 | 23 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008158; F:hedgehog receptor activity; IEA:InterPro. | | | | | | | | | | | 11 | Q61115 | 1434 | PTC1_MOUSE Protein patched homolog 1 OS=Mus m... | 239 | 7e-19 | 97.1 | 26 | 49 | GO:0005576; C:extracellular region; TAS:Roslin.::GO:0005887; C:integral to plasma membrane; TAS:MGI.::GO:0030496; C:midbody; IDA:UniProtKB. | | | | | | | | | | GO:0015485; F:cholesterol binding; TAS:Roslin.::GO:0030332; F:cyclin binding; IPI:BHF-UCL.::GO:0008158; F:hedgehog receptor activity; TAS:MGI.::GO:0008201; F:heparin binding; IDA:Roslin.::GO:0005113; F:patched binding; IDA:Roslin.::GO:0032403; F:protein complex binding; IDA:BHF-UCL.::GO:0008270; F:zinc ion binding; NAS:Roslin. | | | | | | | | | | GO:0007420; P:brain development; IMP:BHF-UCL.::GO:0001658; P:branching involved in ureteric bud morphogenesis; IMP:MGI.::GO:0061005; P:cell differentiation involved in kidney development; IGI:MGI.::GO:0072203; P:cell proliferation involved in metanephros development; IMP:MGI.::GO:0071397; P:cellular response to cholesterol; IEP:BHF-UCL.::GO:0021904; P:dorsal/ventral neural tube patterning; IMP:MGI.::GO:0030326; P:embryonic limb morphogenesis; IMP:MGI.::GO:0008544; P:epidermis development; IMP:MGI.::GO:0042593; P:glucose homeostasis; IMP:MGI.::GO:0003007; P:heart morphogenesis; IMP:MGI.::GO:0035137; P:hindlimb morphogenesis; IMP:MGI.::GO:0043616; P:keratinocyte proliferation; IMP:MGI.::GO:0060603; P:mammary gland duct morphogenesis; IMP:MGI.::GO:0060644; P:mammary gland epithelial cell differentiation; IMP:MGI.::GO:0051782; P:negative regulation of cell division; IMP:BHF-UCL.::GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:MGI.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:MGI.::GO:0045879; P:negative regulation of smoothened signaling pathway; IGI:BHF-UCL.::GO:0021997; P:neural plate axis specification; IMP:BHF-UCL.::GO:0001843; P:neural tube closure; IMP:MGI.::GO:0016485; P:protein processing; IMP:MGI.::GO:0007346; P:regulation of mitotic cell cycle; IMP:MGI.::GO:0032880; P:regulation of protein localization; IDA:BHF-UCL.::GO:0010157; P:response to chlorate; IDA:MGI.::GO:0007224; P:smoothened signaling pathway; IDA:MGI.::GO:0061053; P:somite development; IMP:BHF-UCL. | 12 | Q13635 | 1447 | PTC1_HUMAN Protein patched homolog 1 OS=Homo ... | 209 | 3e-19 | 98.2 | 28 | 51 | GO:0005901; C:caveola; IDA:BHF-UCL.::GO:0005887; C:integral to plasma membrane; ISS:BHF-UCL.::GO:0043231; C:intracellular membrane-bounded organelle; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL. | | | | | | | | | | GO:0015485; F:cholesterol binding; IDA:BHF-UCL.::GO:0030332; F:cyclin binding; IPI:BHF-UCL.::GO:0097108; F:hedgehog family protein binding; IPI:BHF-UCL.::GO:0008158; F:hedgehog receptor activity; IEA:InterPro.::GO:0005119; F:smoothened binding; IPI:BHF-UCL. | | | | | | | | | | GO:0007420; P:brain development; ISS:BHF-UCL.::GO:0071397; P:cellular response to cholesterol; IMP:BHF-UCL.::GO:0030326; P:embryonic limb morphogenesis; ISS:UniProtKB.::GO:0040015; P:negative regulation of multicellular organism growth; ISS:UniProtKB.::GO:0045668; P:negative regulation of osteoblast differentiation; IMP:BHF-UCL.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.::GO:0045879; P:negative regulation of smoothened signaling pathway; ISS:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0021997; P:neural plate axis specification; ISS:BHF-UCL.::GO:0060037; P:pharyngeal system development; IMP:BHF-UCL.::GO:0010875; P:positive regulation of cholesterol efflux; IDA:BHF-UCL.::GO:0016485; P:protein processing; ISS:UniProtKB.::GO:0072661; P:protein targeting to plasma membrane; IDA:BHF-UCL.::GO:0007224; P:smoothened signaling pathway; IEP:UniProtKB.::GO:0061053; P:somite development; IMP:BHF-UCL. | 13 | Q3KNS1 | 767 | PTHD3_HUMAN Patched domain-containing protein... | 618 | 2e-20 | 101 | 22 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008158; F:hedgehog receptor activity; IEA:InterPro. | | | | | | | | | | GO:0007286; P:spermatid development; NAS:UniProtKB. | 14 | Q09614 | 1408 | PTC1_CAEEL Protein patched homolog 1 OS=Caeno... | 221 | 0.000000000000002 | 85.5 | 29 | 46 | GO:0005887; C:integral to plasma membrane; IDA:WormBase. | | | | | | | | | | GO:0008158; F:hedgehog receptor activity; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0019915; P:lipid storage; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase. | 15 | Q90693 | 1442 | PTC1_CHICK Protein patched homolog 1 OS=Gallu... | 136 | 0.51 | 38.5 | 28 | 46 | GO:0005887; C:integral to plasma membrane; NAS:Roslin. | | | | | | | | | | GO:0008158; F:hedgehog receptor activity; IEA:InterPro. | | | | | | | | | | GO:0007224; P:smoothened signaling pathway; NAS:Roslin. | 16 | O35595 | 1182 | PTC2_MOUSE Protein patched homolog 2 OS=Mus m... | 186 | 0.00000000000007 | 80.5 | 28 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008158; F:hedgehog receptor activity; IEA:InterPro. | | | | | | | | | | GO:0042633; P:hair cycle; IMP:MGI.::GO:0043588; P:skin development; IMP:MGI. | 17 | Q6GQT6 | 1276 | SCAP_MOUSE Sterol regulatory element-binding ... | 241 | 7e-19 | 97.1 | 28 | 52 | GO:0005789; C:endoplasmic reticulum membrane; IDA:MGI.::GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015485; F:cholesterol binding; TAS:MGI.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IDA:MGI.::GO:0045540; P:regulation of cholesterol biosynthetic process; IMP:MGI.::GO:0042304; P:regulation of fatty acid biosynthetic process; IMP:MGI.::GO:0001666; P:response to hypoxia; IMP:MGI.::GO:0032868; P:response to insulin stimulus; IMP:MGI. | 18 | Q9Y6C5 | 1203 | PTC2_HUMAN Protein patched homolog 2 OS=Homo ... | 186 | 0.0000000000004 | 78.2 | 28 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0097108; F:hedgehog family protein binding; IPI:BHF-UCL.::GO:0008158; F:hedgehog receptor activity; TAS:BHF-UCL.::GO:0005119; F:smoothened binding; IPI:BHF-UCL. | | | | | | | | | | GO:0045879; P:negative regulation of smoothened signaling pathway; TAS:BHF-UCL. | 19 | Q12770 | 1279 | SCAP_HUMAN Sterol regulatory element-binding ... | 241 | 2e-18 | 95.9 | 27 | 52 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; NAS:UniProtKB. | | | | | | | | | | GO:0051082; F:unfolded protein binding; NAS:UniProtKB. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0045541; P:negative regulation of cholesterol biosynthetic process; NAS:UniProtKB.::GO:0045716; P:positive regulation of low-density lipoprotein particle receptor biosynthetic process; NAS:UniProtKB.::GO:0006994; P:positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathway; IMP:UniProtKB. | 20 | A2RRU4 | 1276 | SCAP_RAT Sterol regulatory element-binding pr... | 241 | 2e-18 | 95.5 | 27 | 52 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD. | | | | | | | | | | | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW. | 21 | P97260 | 1276 | SCAP_CRIGR Sterol regulatory element-binding ... | 241 | 3e-18 | 94.7 | 27 | 52 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008022; F:protein C-terminus binding; IPI:UniProtKB. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006994; P:positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathway; ISS:UniProtKB.::GO:0006993; P:sterol regulatory element binding protein import into nucleus involved in sterol depletion response; IMP:UniProtKB. | 22 | Q5MNU5 | 1279 | SCAP_PIG Sterol regulatory element-binding pr... | 223 | 5e-18 | 94 | 27 | 53 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW. | 23 | A6QM06 | 1278 | SCAP_BOVIN Sterol regulatory element-binding ... | 223 | 8e-18 | 93.6 | 27 | 53 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW. | 24 | Q98864 | 1220 | PTC1_DANRE Protein patched homolog 1 OS=Danio... | 151 | 0.000000000001 | 76.6 | 32 | 54 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008158; F:hedgehog receptor activity; IEA:InterPro. | | | | | | | | | | | 25 | P18502 | 1286 | PTC_DROME Protein patched OS=Drosophila melan... | 198 | 0.0000003 | 58.9 | 29 | 52 | GO:0030139; C:endocytic vesicle; IDA:FlyBase.::GO:0005887; C:integral to plasma membrane; TAS:FlyBase.::GO:0048471; C:perinuclear region of cytoplasm; IDA:FlyBase. | | | | | | | | | | GO:0008158; F:hedgehog receptor activity; IMP:FlyBase.::GO:0030228; F:lipoprotein particle receptor activity; IDA:FlyBase.::GO:0005515; F:protein binding; IPI:FlyBase. | | | | | | | | | | GO:0048099; P:anterior/posterior lineage restriction, imaginal disc; TAS:FlyBase.::GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0001746; P:Bolwig's organ morphogenesis; IMP:FlyBase.::GO:0016311; P:dephosphorylation; TAS:FlyBase.::GO:0035225; P:determination of genital disc primordium; IMP:FlyBase.::GO:0007455; P:eye-antennal disc morphogenesis; IMP:FlyBase.::GO:0042078; P:germ-line stem cell division; TAS:FlyBase.::GO:0008406; P:gonad development; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0055088; P:lipid homeostasis; IMP:FlyBase.::GO:0045879; P:negative regulation of smoothened signaling pathway; IGI:FlyBase.::GO:0030707; P:ovarian follicle cell development; TAS:FlyBase.::GO:0007422; P:peripheral nervous system development; TAS:FlyBase.::GO:0006508; P:proteolysis; TAS:FlyBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:FlyBase.::GO:0042306; P:regulation of protein import into nucleus; IMP:FlyBase.::GO:0007367; P:segment polarity determination; IEA:UniProtKB-KW.::GO:0007224; P:smoothened signaling pathway; IMP:FlyBase.::GO:0048103; P:somatic stem cell division; TAS:FlyBase.::GO:0048100; P:wing disc anterior/posterior pattern formation; TAS:FlyBase. | 26 | A0JPH4 | 1311 | SCAP_XENLA Sterol regulatory element-binding ... | 223 | 4e-17 | 91.3 | 26 | 52 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW. | 27 | B9EKX1 | 904 | PTHD4_MOUSE Patched domain-containing protein... | 932 | 2e-16 | 88.6 | 20 | 38 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008158; F:hedgehog receptor activity; IEA:InterPro. | | | | | | | | | | | 28 | Q96NR3 | 888 | PTHD1_HUMAN Patched domain-containing protein... | 849 | 0.00000000000004 | 81.3 | 20 | 38 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0008158; F:hedgehog receptor activity; IEA:InterPro. | | | | | | | | | | GO:0050890; P:cognition; IMP:UniProtKB.::GO:0007224; P:smoothened signaling pathway; IDA:UniProtKB. | 29 | Q6ZW05 | 846 | PTHD4_HUMAN Patched domain-containing protein... | 735 | 0.00000000000006 | 80.5 | 19 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008158; F:hedgehog receptor activity; IEA:InterPro. | | | | | | | | | | | 30 | Q14B62 | 888 | PTHD1_MOUSE Patched domain-containing protein... | 849 | 0.0000000000002 | 79 | 19 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008158; F:hedgehog receptor activity; IEA:InterPro. | | | | | | | | | | | 31 | Q03602 | 844 | PTR9_CAEEL Patched-related protein 9 OS=Caeno... | 183 | 0.000007 | 54.3 | 23 | 44 | GO:0016021; C:integral to membrane; IEA:InterPro. | | | | | | | | | | | | | | | | | | | | GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase. |