| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | O42565 | 615 | LIMK1_XENLA LIM domain kinase 1 OS=Xenopus la... | 238 | 0.0002 | 48.1 | 22 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 62 | Q61846 | 643 | MELK_MOUSE Maternal embryonic leucine zipper ... | 153 | 0.0002 | 48.5 | 28 | 46 | GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030097; P:hemopoiesis; ISS:UniProtKB.::GO:0061351; P:neural precursor cell proliferation; IDA:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB. | 63 | P06782 | 633 | SNF1_YEAST Carbon catabolite-derepressing pro... | 148 | 0.0002 | 48.1 | 26 | 44 | GO:0031588; C:AMP-activated protein kinase complex; IDA:SGD.::GO:0000324; C:fungal-type vacuole; IPI:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005641; C:nuclear envelope lumen; IDA:SGD.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004679; F:AMP-activated protein kinase activity; IDA:SGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0042710; P:biofilm formation; IMP:SGD.::GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IMP:SGD.::GO:0006995; P:cellular response to nitrogen starvation; IDA:SGD.::GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0017148; P:negative regulation of translation; IMP:SGD.::GO:0045722; P:positive regulation of gluconeogenesis; IMP:SGD.::GO:0007124; P:pseudohyphal growth; IMP:SGD.::GO:0001302; P:replicative cell aging; IMP:SGD.::GO:0007165; P:signal transduction; TAS:SGD. | 64 | Q10SC8 | 456 | CIPK9_ORYSJ CBL-interacting protein kinase 9 ... | 162 | 0.0002 | 48.1 | 29 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 65 | Q03137 | 986 | EPHA4_MOUSE Ephrin type-A receptor 4 OS=Mus m... | 271 | 0.0002 | 48.5 | 22 | 41 | GO:0030424; C:axon; IDA:UniProtKB.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0031901; C:early endosome membrane; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0097161; F:DH domain binding; ISS:UniProtKB.::GO:0005004; F:GPI-linked ephrin receptor activity; IMP:UniProtKB.::GO:0005005; F:transmembrane-ephrin receptor activity; IDA:UniProtKB. | | | | | | | | | | GO:0007628; P:adult walking behavior; IMP:MGI.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0021957; P:corticospinal tract morphogenesis; IMP:UniProtKB.::GO:0097156; P:fasciculation of motor neuron axon; IMP:UniProtKB.::GO:0097155; P:fasciculation of sensory neuron axon; IMP:UniProtKB.::GO:0008045; P:motor axon guidance; IMP:UniProtKB.::GO:0048681; P:negative regulation of axon regeneration; IMP:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; IDA:BHF-UCL.::GO:2001108; P:positive regulation of Rho guanyl-nucleotide exchange factor activity; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0048710; P:regulation of astrocyte differentiation; IMP:UniProtKB.::GO:0061001; P:regulation of dendritic spine morphogenesis; IMP:UniProtKB.::GO:0032314; P:regulation of Rac GTPase activity; IDA:UniProtKB.::GO:0032317; P:regulation of Rap GTPase activity; IMP:UniProtKB. | 66 | Q91ZU0 | 318 | ASB7_MOUSE Ankyrin repeat and SOCS box protei... | 105 | 1.1 | 36.2 | 25 | 49 | | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 67 | Q9BGT9 | 318 | ASB7_MACFA Ankyrin repeat and SOCS box protei... | 105 | 1.3 | 35.8 | 25 | 48 | | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 68 | P22216 | 821 | RAD53_YEAST Serine/threonine-protein kinase R... | 163 | 0.0002 | 48.5 | 29 | 42 | GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003688; F:DNA replication origin binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IDA:SGD.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0009202; P:deoxyribonucleoside triphosphate biosynthetic process; IMP:SGD.::GO:0006281; P:DNA repair; IMP:SGD.::GO:0006270; P:DNA-dependent DNA replication initiation; IMP:SGD.::GO:0008104; P:protein localization; IMP:SGD. | 69 | Q62689 | 1132 | JAK2_RAT Tyrosine-protein kinase JAK2 OS=Ratt... | 232 | 0.0002 | 48.5 | 22 | 43 | GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0005829; C:cytosol; IDA:RGD.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0016363; C:nuclear matrix; IDA:RGD. | | | | | | | | | | GO:0033130; F:acetylcholine receptor binding; IPI:RGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005131; F:growth hormone receptor binding; IPI:BHF-UCL.::GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0035401; F:histone kinase activity (H3-Y41 specific); ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; IPI:RGD.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:Reactome.::GO:0051428; F:peptide hormone receptor binding; IPI:RGD.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:RGD.::GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0031702; F:type 1 angiotensin receptor binding; IPI:RGD. | | | | | | | | | | GO:0042977; P:activation of JAK2 kinase activity; ISS:UniProtKB.::GO:0000186; P:activation of MAPKK activity; IMP:RGD.::GO:0031103; P:axon regeneration; IMP:RGD.::GO:0007204; P:elevation of cytosolic calcium ion concentration; IMP:RGD.::GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0007186; P:G-protein coupled receptor signaling pathway; IMP:RGD.::GO:0009755; P:hormone-mediated signaling pathway; IDA:RGD.::GO:0008631; P:induction of apoptosis by oxidative stress; IMP:RGD.::GO:0060333; P:interferon-gamma-mediated signaling pathway; IDA:BHF-UCL.::GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; ISS:UniProtKB.::GO:0031959; P:mineralocorticoid receptor signaling pathway; IMP:RGD.::GO:0022408; P:negative regulation of cell-cell adhesion; IMP:RGD.::GO:0045822; P:negative regulation of heart contraction; IMP:RGD.::GO:0043526; P:neuroprotection; IMP:RGD.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IMP:RGD.::GO:0050867; P:positive regulation of cell activation; IMP:RGD.::GO:0045597; P:positive regulation of cell differentiation; IMP:RGD.::GO:0030335; P:positive regulation of cell migration; IMP:RGD.::GO:0008284; P:positive regulation of cell proliferation; IMP:RGD.::GO:0043388; P:positive regulation of DNA binding; IMP:RGD.::GO:0050729; P:positive regulation of inflammatory response; IMP:RGD.::GO:0032024; P:positive regulation of insulin secretion; IMP:RGD.::GO:0032731; P:positive regulation of interleukin-1 beta production; IMP:RGD.::GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IMP:RGD.::GO:0051770; P:positive regulation of nitric-oxide synthase biosynthetic process; IDA:BHF-UCL.::GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; IMP:RGD.::GO:0033160; P:positive regulation of protein import into nucleus, translocation; IMP:RGD.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:RGD.::GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0033194; P:response to hydroperoxide; IMP:RGD.::GO:0042508; P:tyrosine phosphorylation of Stat1 protein; IMP:RGD.::GO:0042503; P:tyrosine phosphorylation of Stat3 protein; IMP:RGD.::GO:0042506; P:tyrosine phosphorylation of Stat5 protein; IMP:RGD. | 70 | Q8H569 | 907 | AKT3_ORYSJ Potassium channel AKT3 OS=Oryza sa... | 141 | 0.0002 | 48.5 | 35 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro. | | | | | | | | | | | 71 | B2RXR6 | 993 | ANR44_MOUSE Serine/threonine-protein phosphat... | 142 | 7.9 | 33.5 | 29 | 47 | | | | | | | | | | | | | | | | | | | | | | 72 | P97570 | 751 | PA2G6_RAT 85 kDa calcium-independent phosphol... | 153 | 3.5 | 34.7 | 27 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047499; F:calcium-independent phospholipase A2 activity; IDA:RGD. | | | | | | | | | | GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 73 | Q00372 | 612 | SNF1_CANGA Carbon catabolite-derepressing pro... | 150 | 0.0003 | 48.1 | 26 | 45 | GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW. | 74 | Q5UNT1 | 545 | YL673_MIMIV Putative serine/threonine-protein... | 253 | 0.0003 | 47.8 | 24 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 75 | Q6ZLP5 | 450 | CIPKN_ORYSJ CBL-interacting protein kinase 23... | 152 | 0.0003 | 47.8 | 29 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 76 | F1QGZ6 | 676 | MELK_DANRE Maternal embryonic leucine zipper ... | 151 | 0.0003 | 47.8 | 27 | 45 | GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0048821; P:erythrocyte development; IMP:ZFIN.::GO:0061351; P:neural precursor cell proliferation; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0008016; P:regulation of heart contraction; IMP:ZFIN. | 77 | Q9ULJ7 | 1429 | ANR50_HUMAN Ankyrin repeat domain-containing ... | 150 | 7.1 | 33.9 | 27 | 45 | | | | | | | | | | | | | | | | | | | | | | 78 | O60733 | 806 | PA2G6_HUMAN 85 kDa calcium-independent phosph... | 94 | 1.1 | 36.6 | 29 | 48 | GO:0005813; C:centrosome; IDA:HPA.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0032049; P:cardiolipin biosynthetic process; IMP:UniProtKB.::GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 79 | P57059 | 783 | SIK1_HUMAN Serine/threonine-protein kinase SI... | 143 | 0.0004 | 47.8 | 24 | 46 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0071889; F:14-3-3 protein binding; IDA:UniProtKB.::GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0008140; F:cAMP response element binding protein binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0055007; P:cardiac muscle cell differentiation; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0032792; P:negative regulation of CREB transcription factor activity; ISS:UniProtKB.::GO:0045721; P:negative regulation of gluconeogenesis; ISS:UniProtKB.::GO:0010868; P:negative regulation of triglyceride biosynthetic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0007346; P:regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0010830; P:regulation of myotube differentiation; ISS:UniProtKB.::GO:0002028; P:regulation of sodium ion transport; ISS:UniProtKB.::GO:0072333; P:signal transduction by p53 class mediator resulting in induction of anoikis; IMP:BHF-UCL. | 80 | Q9QYZ3 | 484 | SMK2B_MOUSE Sperm motility kinase 2B OS=Mus m... | 146 | 0.0004 | 47.4 | 29 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 81 | Q02595 | 510 | KPK2_PLAFK Probable serine/threonine-protein ... | 168 | 0.0004 | 47.4 | 24 | 47 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 82 | Q9H4B4 | 646 | PLK3_HUMAN Serine/threonine-protein kinase PL... | 208 | 0.0004 | 47.4 | 26 | 43 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005795; C:Golgi stack; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0002039; F:p53 binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:UniProtKB.::GO:0000910; P:cytokinesis; TAS:UniProtKB.::GO:0007113; P:endomitotic cell cycle; TAS:UniProtKB.::GO:0071779; P:G1/S transition checkpoint; ISS:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:UniProtKB.::GO:0090166; P:Golgi disassembly; IDA:UniProtKB.::GO:0071780; P:mitotic cell cycle G2/M transition checkpoint; TAS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:2000777; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia; IDA:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IDA:UniProtKB.::GO:0006970; P:response to osmotic stress; IDA:UniProtKB.::GO:0009314; P:response to radiation; IDA:UniProtKB.::GO:0000302; P:response to reactive oxygen species; IDA:UniProtKB.::GO:0000084; P:S phase of mitotic cell cycle; IMP:UniProtKB. | 83 | Q4UKX2 | 395 | Y950_RICFE Putative ankyrin repeat protein RF... | 111 | 0.011 | 42.7 | 30 | 50 | | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:InterPro. | | | | | | | | | | GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW. | 84 | Q6PHR2 | 472 | ULK3_HUMAN Serine/threonine-protein kinase UL... | 156 | 0.0004 | 47.4 | 28 | 44 | GO:0000407; C:pre-autophagosomal structure; TAS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006914; P:autophagy; TAS:UniProtKB.::GO:0090398; P:cellular senescence; TAS:UniProtKB.::GO:0045879; P:negative regulation of smoothened signaling pathway; IDA:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB. | 85 | Q8SSH1 | 516 | Y255_ENCCU Probable serine/threonine-protein ... | 150 | 0.0004 | 47.4 | 27 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 86 | Q62120 | 1129 | JAK2_MOUSE Tyrosine-protein kinase JAK2 OS=Mu... | 232 | 0.0004 | 47.8 | 22 | 43 | GO:0005901; C:caveola; IDA:MGI.::GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; ISS:BHF-UCL.::GO:0016363; C:nuclear matrix; ISS:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005131; F:growth hormone receptor binding; ISS:BHF-UCL.::GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0035401; F:histone kinase activity (H3-Y41 specific); ISS:UniProtKB.::GO:0005143; F:interleukin-12 receptor binding; IPI:MGI.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:Reactome.::GO:0019901; F:protein kinase binding; ISS:BHF-UCL. | | | | | | | | | | GO:0008636; P:activation of caspase activity by protein phosphorylation; IDA:BHF-UCL.::GO:0042977; P:activation of JAK2 kinase activity; IDA:UniProtKB.::GO:0000186; P:activation of MAPKK activity; ISS:BHF-UCL.::GO:0031103; P:axon regeneration; ISS:BHF-UCL.::GO:0007204; P:elevation of cytosolic calcium ion concentration; ISS:BHF-UCL.::GO:0030218; P:erythrocyte differentiation; IMP:UniProtKB.::GO:0007186; P:G-protein coupled receptor signaling pathway; ISS:BHF-UCL.::GO:0009755; P:hormone-mediated signaling pathway; ISS:BHF-UCL.::GO:0008631; P:induction of apoptosis by oxidative stress; ISS:BHF-UCL.::GO:0060333; P:interferon-gamma-mediated signaling pathway; ISS:BHF-UCL.::GO:0035722; P:interleukin-12-mediated signaling pathway; ISS:BHF-UCL.::GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; IMP:UniProtKB.::GO:0061180; P:mammary gland epithelium development; IMP:MGI.::GO:0031959; P:mineralocorticoid receptor signaling pathway; ISS:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; IMP:MGI.::GO:0022408; P:negative regulation of cell-cell adhesion; ISS:BHF-UCL.::GO:0043392; P:negative regulation of DNA binding; IDA:MGI.::GO:0045822; P:negative regulation of heart contraction; ISS:BHF-UCL.::GO:0043526; P:neuroprotection; ISS:BHF-UCL.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; ISS:BHF-UCL.::GO:0050867; P:positive regulation of cell activation; ISS:BHF-UCL.::GO:0045597; P:positive regulation of cell differentiation; ISS:BHF-UCL.::GO:0030335; P:positive regulation of cell migration; ISS:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; ISS:BHF-UCL.::GO:0010811; P:positive regulation of cell-substrate adhesion; ISS:BHF-UCL.::GO:0043388; P:positive regulation of DNA binding; ISS:BHF-UCL.::GO:0060399; P:positive regulation of growth hormone receptor signaling pathway; IMP:BHF-UCL.::GO:0050729; P:positive regulation of inflammatory response; ISS:BHF-UCL.::GO:0032024; P:positive regulation of insulin secretion; ISS:BHF-UCL.::GO:0032731; P:positive regulation of interleukin-1 beta production; ISS:BHF-UCL.::GO:0045429; P:positive regulation of nitric oxide biosynthetic process; ISS:BHF-UCL.::GO:0051770; P:positive regulation of nitric-oxide synthase biosynthetic process; IDA:BHF-UCL.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IMP:BHF-UCL.::GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; ISS:BHF-UCL.::GO:0033160; P:positive regulation of protein import into nucleus, translocation; ISS:BHF-UCL.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.::GO:0032760; P:positive regulation of tumor necrosis factor production; IDA:BHF-UCL.::GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; IDA:UniProtKB.::GO:0042523; P:positive regulation of tyrosine phosphorylation of Stat5 protein; IDA:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0097012; P:response to granulocyte macrophage colony-stimulating factor stimulus; NAS:BHF-UCL.::GO:0033194; P:response to hydroperoxide; ISS:BHF-UCL.::GO:0032496; P:response to lipopolysaccharide; IDA:BHF-UCL.::GO:0007262; P:STAT protein import into nucleus; IDA:MGI.::GO:0033209; P:tumor necrosis factor-mediated signaling pathway; ISS:BHF-UCL.::GO:0042508; P:tyrosine phosphorylation of Stat1 protein; ISS:BHF-UCL.::GO:0042503; P:tyrosine phosphorylation of Stat3 protein; ISS:BHF-UCL. | 87 | P54753 | 998 | EPHB3_HUMAN Ephrin type-B receptor 3 OS=Homo ... | 171 | 0.0005 | 47.4 | 25 | 42 | GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005003; F:ephrin receptor activity; IDA:UniProtKB. | | | | | | | | | | GO:0001525; P:angiogenesis; ISS:UniProtKB.::GO:0007413; P:axonal fasciculation; ISS:UniProtKB.::GO:0016477; P:cell migration; IDA:UniProtKB.::GO:0022038; P:corpus callosum development; ISS:UniProtKB.::GO:0060997; P:dendritic spine morphogenesis; ISS:UniProtKB.::GO:0048546; P:digestive tract morphogenesis; ISS:UniProtKB.::GO:0060021; P:palate development; ISS:UniProtKB.::GO:0051965; P:positive regulation of synapse assembly; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0050770; P:regulation of axonogenesis; ISS:UniProtKB.::GO:0043088; P:regulation of Cdc42 GTPase activity; IDA:UniProtKB.::GO:0022407; P:regulation of cell-cell adhesion; IDA:UniProtKB.::GO:0032314; P:regulation of Rac GTPase activity; IDA:UniProtKB.::GO:0034446; P:substrate adhesion-dependent cell spreading; IDA:UniProtKB.::GO:0048538; P:thymus development; ISS:UniProtKB.::GO:0001655; P:urogenital system development; ISS:UniProtKB. | 88 | P54754 | 993 | EPHB3_MOUSE Ephrin type-B receptor 3 OS=Mus m... | 171 | 0.0005 | 47.4 | 25 | 42 | GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008046; F:axon guidance receptor activity; IDA:MGI.::GO:0005005; F:transmembrane-ephrin receptor activity; TAS:MGI. | | | | | | | | | | GO:0001525; P:angiogenesis; IMP:UniProtKB.::GO:0007413; P:axonal fasciculation; IMP:UniProtKB.::GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0021952; P:central nervous system projection neuron axonogenesis; IDA:MGI.::GO:0022038; P:corpus callosum development; IMP:UniProtKB.::GO:0060997; P:dendritic spine morphogenesis; IMP:UniProtKB.::GO:0048546; P:digestive tract morphogenesis; IMP:UniProtKB.::GO:0060021; P:palate development; IMP:UniProtKB.::GO:0051965; P:positive regulation of synapse assembly; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0050770; P:regulation of axonogenesis; IDA:UniProtKB.::GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0022407; P:regulation of cell-cell adhesion; ISS:UniProtKB.::GO:0032314; P:regulation of Rac GTPase activity; ISS:UniProtKB.::GO:0031290; P:retinal ganglion cell axon guidance; IDA:MGI.::GO:0034446; P:substrate adhesion-dependent cell spreading; ISS:UniProtKB.::GO:0048538; P:thymus development; IMP:UniProtKB.::GO:0001655; P:urogenital system development; IMP:UniProtKB. | 89 | P31374 | 1356 | PSK1_YEAST Serine/threonine-protein kinase PS... | 206 | 0.0005 | 47.4 | 24 | 45 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IMP:SGD.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0045719; P:negative regulation of glycogen biosynthetic process; IMP:SGD.::GO:0060917; P:regulation of (1->6)-beta-D-glucan biosynthetic process; IGI:SGD.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. | 90 | Q9IA88 | 798 | SIK2_CHICK Serine/threonine-protein kinase SI... | 143 | 0.0006 | 47 | 25 | 45 | GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0046626; P:regulation of insulin receptor signaling pathway; ISS:UniProtKB. | 91 | Q1HKZ5 | 959 | M3K13_MOUSE Mitogen-activated protein kinase ... | 164 | 0.0006 | 47 | 24 | 45 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC. | | | | | | | | | | |
