| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P28776 | 407 | I23O1_MOUSE Indoleamine 2,3-dioxygenase 1 OS=... | 409 | 4e-16 | 84 | 23 | 44 | GO:0030485; C:smooth muscle contractile fiber; IDA:MGI.::GO:0032421; C:stereocilium bundle; IDA:MGI. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0033754; F:indoleamine 2,3-dioxygenase activity; IEA:EC.::GO:0004833; F:tryptophan 2,3-dioxygenase activity; IDA:MGI. | | | | | | | | | | GO:0007610; P:behavior; IMP:MGI.::GO:0002534; P:cytokine production involved in inflammatory response; IMP:MGI.::GO:0034276; P:kynurenic acid biosynthetic process; IMP:MGI.::GO:0033555; P:multicellular organismal response to stress; IMP:MGI.::GO:0046007; P:negative regulation of activated T cell proliferation; IMP:MGI.::GO:0032693; P:negative regulation of interleukin-10 production; IMP:MGI.::GO:0070233; P:negative regulation of T cell apoptotic process; IMP:MGI.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.::GO:0002678; P:positive regulation of chronic inflammatory response; IMP:MGI.::GO:0032735; P:positive regulation of interleukin-12 production; IMP:MGI.::GO:0002666; P:positive regulation of T cell tolerance induction; IMP:MGI.::GO:0002830; P:positive regulation of type 2 immune response; IMP:MGI.::GO:0032496; P:response to lipopolysaccharide; IMP:MGI.::GO:0019441; P:tryptophan catabolic process to kynurenine; IDA:MGI. | 2 | P47125 | 453 | I23O_YEAST Indoleamine 2,3-dioxygenase family... | 407 | 0.00000000000003 | 78.2 | 24 | 41 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0033754; F:indoleamine 2,3-dioxygenase activity; NAS:SGD.::GO:0004833; F:tryptophan 2,3-dioxygenase activity; NAS:SGD. | | | | | | | | | | GO:0034354; P:de novo NAD biosynthetic process from tryptophan; IGI:SGD. | 3 | Q9ERD9 | 407 | I23O1_RAT Indoleamine 2,3-dioxygenase 1 OS=Ra... | 408 | 0.00000000000004 | 77.8 | 22 | 42 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0016597; F:amino acid binding; IDA:RGD.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0033754; F:indoleamine 2,3-dioxygenase activity; IDA:RGD.::GO:0019825; F:oxygen binding; IDA:RGD. | | | | | | | | | | GO:0019441; P:tryptophan catabolic process to kynurenine; IDA:RGD. | 4 | P14902 | 403 | I23O1_HUMAN Indoleamine 2,3-dioxygenase 1 OS=... | 341 | 0.000000000003 | 72 | 23 | 43 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0033754; F:indoleamine 2,3-dioxygenase activity; IEA:EC.::GO:0004833; F:tryptophan 2,3-dioxygenase activity; EXP:Reactome. | | | | | | | | | | GO:0007565; P:female pregnancy; TAS:ProtInc.::GO:0006569; P:tryptophan catabolic process; TAS:Reactome. | 5 | Q6ZQW0 | 407 | I23O2_HUMAN Indoleamine 2,3-dioxygenase 2 OS=... | 404 | 0.00000000002 | 69.7 | 23 | 41 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0033754; F:indoleamine 2,3-dioxygenase activity; IDA:UniProtKB.::GO:0004833; F:tryptophan 2,3-dioxygenase activity; EXP:Reactome. | | | | | | | | | | GO:0019441; P:tryptophan catabolic process to kynurenine; IDA:UniProtKB. | 6 | Q8R0V5 | 398 | I23O2_MOUSE Indoleamine 2,3-dioxygenase 2 OS=... | 402 | 0.0000000001 | 67 | 22 | 40 | | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | | 7 | P51537 | 378 | MYG_HALMK Myoglobin OS=Haliotis madaka (Giant... | 341 | 0.001 | 44.7 | 25 | 40 | | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 8 | Q01966 | 378 | MYG_HALDV Myoglobin OS=Haliotis diversicolor ... | 335 | 0.29 | 37.4 | 25 | 39 | | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 9 | Q2GCH7 | 166 | RUVC_NEOSM Crossover junction endodeoxyribonu... | 80 | 5.5 | 32.3 | 26 | 51 | | | | | | | | | | | GO:0008821; F:crossover junction endodeoxyribonuclease activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro. | | | | | | | | | | GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 10 | C5BEU1 | 616 | HSCA_EDWI9 Chaperone protein HscA OS=Edwardsi... | 75 | 7.3 | 33.1 | 33 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro. | | | | | | | | | | GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.::GO:0006457; P:protein folding; IEA:InterPro. |
