rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | Q63ZT8 | 902 | AL1L1_XENTR Cytosolic 10-formyltetrahydrofola... | 362 | 2e-34 | 141 | 30 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016155; F:formyltetrahydrofolate dehydrogenase activity; IEA:EC.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0009258; P:10-formyltetrahydrofolate catabolic process; IEA:InterPro.::GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 92 | B9F3B6 | 527 | SSDH_ORYSJ Succinate-semialdehyde dehydrogena... | 337 | 3e-34 | 138 | 31 | 49 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004777; F:succinate-semialdehyde dehydrogenase activity; IEA:EC. | | | | | | | | | | | 93 | O94788 | 518 | AL1A2_HUMAN Retinal dehydrogenase 2 OS=Homo s... | 453 | 3e-34 | 138 | 27 | 45 | GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0004028; F:3-chloroallyl aldehyde dehydrogenase activity; ISS:UniProtKB.::GO:0016918; F:retinal binding; ISS:UniProtKB.::GO:0001758; F:retinal dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0021915; P:neural tube development; IMP:UniProtKB.::GO:0034097; P:response to cytokine stimulus; IDA:UniProtKB. | 94 | O35945 | 501 | AL1A7_MOUSE Aldehyde dehydrogenase, cytosolic... | 448 | 6e-34 | 137 | 29 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IEA:EC. | | | | | | | | | | | 95 | Q63639 | 518 | AL1A2_RAT Retinal dehydrogenase 2 OS=Rattus n... | 452 | 9e-34 | 137 | 27 | 45 | GO:0005829; C:cytosol; IDA:RGD. | | | | | | | | | | GO:0016918; F:retinal binding; IDA:RGD.::GO:0001758; F:retinal dehydrogenase activity; IDA:RGD. | | | | | | | | | | GO:0001822; P:kidney development; IEP:RGD.::GO:0001889; P:liver development; IEP:RGD.::GO:0007494; P:midgut development; IEP:RGD.::GO:0021983; P:pituitary gland development; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD. | 96 | Q802W2 | 518 | A9A1B_DANRE Aldehyde dehydrogenase family 9 m... | 459 | 9e-34 | 137 | 25 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IEA:EC. | | | | | | | | | | | 97 | Q2KJH9 | 494 | AL9A1_BOVIN 4-trimethylaminobutyraldehyde deh... | 454 | 1e-33 | 137 | 26 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047105; F:4-trimethylammoniobutyraldehyde dehydrogenase activity; IEA:EC.::GO:0019145; F:aminobutyraldehyde dehydrogenase activity; ISS:AgBase. | | | | | | | | | | GO:0006081; P:cellular aldehyde metabolic process; ISS:AgBase.::GO:0042136; P:neurotransmitter biosynthetic process; ISS:AgBase. | 98 | Q62148 | 518 | AL1A2_MOUSE Retinal dehydrogenase 2 OS=Mus mu... | 452 | 1e-33 | 137 | 27 | 45 | | | | | | | | | | | GO:0004028; F:3-chloroallyl aldehyde dehydrogenase activity; IDA:MGI.::GO:0001758; F:retinal dehydrogenase activity; IDA:MGI. | | | | | | | | | | GO:0042904; P:9-cis-retinoic acid biosynthetic process; IDA:MGI.::GO:0009952; P:anterior/posterior pattern specification; IMP:MGI.::GO:0001568; P:blood vessel development; IMP:MGI.::GO:0071300; P:cellular response to retinoic acid; IEP:UniProtKB.::GO:0031076; P:embryonic camera-type eye development; IGI:MGI.::GO:0048566; P:embryonic digestive tract development; IMP:MGI.::GO:0035115; P:embryonic forelimb morphogenesis; IMP:MGI.::GO:0060324; P:face development; IMP:MGI.::GO:0001947; P:heart looping; TAS:DFLAT.::GO:0030902; P:hindbrain development; IMP:MGI.::GO:0030324; P:lung development; IMP:MGI.::GO:0016331; P:morphogenesis of embryonic epithelium; IMP:MGI.::GO:0014032; P:neural crest cell development; IMP:MGI.::GO:0030182; P:neuron differentiation; IMP:MGI.::GO:0031016; P:pancreas development; IMP:MGI.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.::GO:0008284; P:positive regulation of cell proliferation; IMP:MGI.::GO:0010628; P:positive regulation of gene expression; IMP:MGI.::GO:0009954; P:proximal/distal pattern formation; IMP:MGI.::GO:0001936; P:regulation of endothelial cell proliferation; IMP:MGI.::GO:0042574; P:retinal metabolic process; IDA:MGI.::GO:0048384; P:retinoic acid receptor signaling pathway; IMP:MGI.::GO:0035799; P:ureter maturation; IMP:MGI. | 99 | O93344 | 518 | AL1A2_CHICK Retinal dehydrogenase 2 OS=Gallus... | 430 | 1e-33 | 136 | 27 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0001758; F:retinal dehydrogenase activity; IEA:EC. | | | | | | | | | | | 100 | P49189 | 494 | AL9A1_HUMAN 4-trimethylaminobutyraldehyde deh... | 454 | 2e-33 | 136 | 26 | 43 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0033737; F:1-pyrroline dehydrogenase activity; IEA:EC.::GO:0004028; F:3-chloroallyl aldehyde dehydrogenase activity; TAS:Reactome.::GO:0047105; F:4-trimethylammoniobutyraldehyde dehydrogenase activity; IEA:EC.::GO:0019145; F:aminobutyraldehyde dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0045329; P:carnitine biosynthetic process; TAS:Reactome.::GO:0006081; P:cellular aldehyde metabolic process; IDA:UniProtKB.::GO:0042445; P:hormone metabolic process; TAS:UniProtKB.::GO:0042136; P:neurotransmitter biosynthetic process; IDA:UniProtKB. | 101 | A6VH72 | 465 | LADH_METM7 Lactaldehyde dehydrogenase OS=Meth... | 344 | 2e-33 | 135 | 29 | 49 | | | | | | | | | | | GO:0008911; F:lactaldehyde dehydrogenase activity; IEA:EC. | | | | | | | | | | | 102 | C3K3D2 | 490 | BETB_PSEFS Betaine aldehyde dehydrogenase OS=... | 378 | 3e-33 | 135 | 29 | 47 | | | | | | | | | | | GO:0008802; F:betaine-aldehyde dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0006578; P:betaine biosynthetic process; IEA:InterPro. | 103 | A6W2P7 | 485 | BETB_MARMS Betaine aldehyde dehydrogenase OS=... | 415 | 3e-33 | 135 | 26 | 46 | | | | | | | | | | | GO:0008802; F:betaine-aldehyde dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0006578; P:betaine biosynthetic process; IEA:InterPro. | 104 | Q28399 | 501 | ALDH1_ELEED Aldehyde dehydrogenase, cytosolic... | 355 | 3e-33 | 135 | 30 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IEA:EC. | | | | | | | | | | | 105 | Q3SY69 | 923 | AL1L2_HUMAN Mitochondrial 10-formyltetrahydro... | 362 | 4e-33 | 138 | 31 | 47 | GO:0005739; C:mitochondrion; IDA:HPA. | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016155; F:formyltetrahydrofolate dehydrogenase activity; IEA:EC.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro. | | | | | | | | | | GO:0009258; P:10-formyltetrahydrofolate catabolic process; IEA:InterPro.::GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 106 | Q7ZVB2 | 508 | A9A1A_DANRE Aldehyde dehydrogenase family 9 m... | 448 | 4e-33 | 135 | 26 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IEA:EC. | | | | | | | | | | | 107 | Q5R8A4 | 494 | AL9A1_PONAB 4-trimethylaminobutyraldehyde deh... | 356 | 5e-33 | 134 | 28 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047105; F:4-trimethylammoniobutyraldehyde dehydrogenase activity; IEA:EC.::GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IEA:EC. | | | | | | | | | | | 108 | Q6GNL7 | 902 | AL1L1_XENLA Cytosolic 10-formyltetrahydrofola... | 361 | 7e-33 | 137 | 30 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016155; F:formyltetrahydrofolate dehydrogenase activity; IEA:EC.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0009258; P:10-formyltetrahydrofolate catabolic process; IEA:InterPro.::GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 109 | Q8UH56 | 493 | BETB_AGRT5 Betaine aldehyde dehydrogenase OS=... | 355 | 8e-33 | 134 | 30 | 48 | | | | | | | | | | | GO:0008802; F:betaine-aldehyde dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0006578; P:betaine biosynthetic process; IEA:InterPro. | 110 | Q9SU63 | 538 | AL2B4_ARATH Aldehyde dehydrogenase family 2 m... | 407 | 9e-33 | 134 | 29 | 47 | GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IEA:EC.::GO:0005524; F:ATP binding; IDA:TAIR. | | | | | | | | | | GO:0046686; P:response to cadmium ion; IEP:TAIR. | 111 | Q8HYE4 | 501 | AL1A1_MACFA Retinal dehydrogenase 1 OS=Macaca... | 451 | 1e-32 | 134 | 27 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0001758; F:retinal dehydrogenase activity; IEA:EC. | | | | | | | | | | | 112 | O69497 | 457 | GABD1_MYCLE Succinate-semialdehyde dehydrogen... | 351 | 1e-32 | 133 | 28 | 46 | | | | | | | | | | | GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 113 | Q29490 | 501 | ALDH1_MACPR Aldehyde dehydrogenase, cytosolic... | 355 | 2e-32 | 133 | 30 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IEA:EC. | | | | | | | | | | | 114 | Q8MI17 | 496 | AL1A1_RABIT Retinal dehydrogenase 1 OS=Orycto... | 448 | 2e-32 | 133 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0001758; F:retinal dehydrogenase activity; IEA:EC. | | | | | | | | | | | 115 | P0A390 | 483 | NAHF_PSEU8 Salicylaldehyde dehydrogenase OS=P... | 487 | 2e-32 | 132 | 28 | 43 | | | | | | | | | | | GO:0018485; F:salicylaldehyde dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW. | 116 | P0A391 | 483 | NAHF_PSEPU Salicylaldehyde dehydrogenase OS=P... | 487 | 2e-32 | 132 | 28 | 43 | | | | | | | | | | | GO:0018485; F:salicylaldehyde dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW. | 117 | P42041 | 497 | ALDH_ALTAL Aldehyde dehydrogenase OS=Alternar... | 415 | 2e-32 | 132 | 27 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IEA:EC. | | | | | | | | | | | 118 | P27463 | 509 | AL1A1_CHICK Retinal dehydrogenase 1 OS=Gallus... | 345 | 3e-32 | 132 | 28 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0001758; F:retinal dehydrogenase activity; IEA:EC. | | | | | | | | | | | 119 | B9JBA3 | 487 | BETB_AGRRK Betaine aldehyde dehydrogenase OS=... | 338 | 3e-32 | 132 | 31 | 49 | | | | | | | | | | | GO:0008802; F:betaine-aldehyde dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0006578; P:betaine biosynthetic process; IEA:InterPro. | 120 | P00352 | 501 | AL1A1_HUMAN Retinal dehydrogenase 1 OS=Homo s... | 447 | 4e-32 | 132 | 27 | 47 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0004029; F:aldehyde dehydrogenase (NAD) activity; EXP:Reactome.::GO:0005497; F:androgen binding; TAS:ProtInc.::GO:0005099; F:Ras GTPase activator activity; TAS:UniProtKB.::GO:0001758; F:retinal dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0006081; P:cellular aldehyde metabolic process; TAS:ProtInc.::GO:0006069; P:ethanol oxidation; TAS:Reactome.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 121 | P48644 | 501 | AL1A1_BOVIN Retinal dehydrogenase 1 OS=Bos ta... | 433 | 4e-32 | 132 | 27 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0001758; F:retinal dehydrogenase activity; IEA:EC. | | | | | | | | | | |