| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
271 | Q9JI11 | 487 | STK4_MOUSE Serine/threonine-protein kinase 4 ... | 246 | 0.000000000001 | 74.3 | 26 | 42 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0060706; P:cell differentiation involved in embryonic placenta development; IGI:MGI.::GO:0007417; P:central nervous system development; IGI:MGI.::GO:0003157; P:endocardium development; IGI:MGI.::GO:0035329; P:hippo signaling cascade; IMP:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IGI:MGI.::GO:0008285; P:negative regulation of cell proliferation; IGI:MGI.::GO:0046621; P:negative regulation of organ growth; IGI:MGI.::GO:0001841; P:neural tube formation; IGI:MGI.::GO:0001569; P:patterning of blood vessels; IGI:MGI.::GO:0060215; P:primitive hemopoiesis; IGI:MGI. | 272 | Q6CSX2 | 831 | ATG1_KLULA Serine/threonine-protein kinase AT... | 271 | 0.000000000001 | 75.1 | 25 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 273 | P24381 | 390 | US03_SUHVN Serine/threonine-protein kinase US... | 190 | 0.000000000001 | 73.9 | 32 | 43 | GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.::GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW. | 274 | Q10407 | 1116 | MKH1_SCHPO MAP kinase kinase kinase mkh1 OS=S... | 309 | 0.000000000001 | 75.1 | 25 | 41 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0030428; C:cell septum; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase. | | | | | | | | | | GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0033205; P:cell cycle cytokinesis; NAS:PomBase.::GO:0034605; P:cellular response to heat; IMP:PomBase.::GO:0071470; P:cellular response to osmotic stress; IMP:PomBase.::GO:0006883; P:cellular sodium ion homeostasis; NAS:PomBase.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:PomBase.::GO:0031505; P:fungal-type cell wall organization; IMP:PomBase.::GO:0050850; P:positive regulation of calcium-mediated signaling; IMP:PomBase.::GO:0008360; P:regulation of cell shape; NAS:PomBase. | 275 | P16879 | 822 | FES_MOUSE Tyrosine-protein kinase Fes/Fps OS=... | 307 | 0.000000000001 | 75.1 | 27 | 41 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0031234; C:extrinsic to internal side of plasma membrane; ISS:UniProtKB.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0015630; C:microtubule cytoskeleton; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0034987; F:immunoglobulin receptor binding; ISS:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB. | | | | | | | | | | GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:2000251; P:positive regulation of actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0031116; P:positive regulation of microtubule polymerization; ISS:UniProtKB.::GO:0045639; P:positive regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0030155; P:regulation of cell adhesion; ISS:UniProtKB.::GO:2000145; P:regulation of cell motility; ISS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0043304; P:regulation of mast cell degranulation; ISS:UniProtKB. | 276 | Q6VNS1 | 825 | NTRK3_MOUSE NT-3 growth factor receptor OS=Mu... | 320 | 0.000000000001 | 75.1 | 26 | 42 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0042490; P:mechanoreceptor differentiation; IMP:MGI.::GO:0048691; P:positive regulation of axon extension involved in regeneration; IGI:MGI.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. | 277 | A7E3S4 | 648 | RAF1_BOVIN RAF proto-oncogene serine/threonin... | 199 | 0.000000000001 | 74.7 | 30 | 46 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 278 | Q8WMV0 | 552 | GRK7_BOVIN G protein-coupled receptor kinase ... | 326 | 0.000000000001 | 74.3 | 25 | 43 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:EC.::GO:0050254; F:rhodopsin kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 279 | Q5IS37 | 825 | NTRK3_PANTR NT-3 growth factor receptor OS=Pa... | 320 | 0.000000000001 | 74.7 | 26 | 42 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005030; F:neurotrophin receptor activity; IEA:InterPro.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. | 280 | Q06807 | 1125 | TIE2_BOVIN Angiopoietin-1 receptor OS=Bos tau... | 315 | 0.000000000001 | 75.1 | 29 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0001935; P:endothelial cell proliferation; ISS:UniProtKB.::GO:0060347; P:heart trabecula formation; ISS:UniProtKB.::GO:0016525; P:negative regulation of angiogenesis; ISS:UniProtKB.::GO:2000352; P:negative regulation of endothelial cell apoptotic process; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0010595; P:positive regulation of endothelial cell migration; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0051894; P:positive regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; ISS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; ISS:UniProtKB.::GO:0002040; P:sprouting angiogenesis; ISS:UniProtKB.::GO:0034446; P:substrate adhesion-dependent cell spreading; ISS:UniProtKB.::GO:0048014; P:Tie receptor signaling pathway; ISS:UniProtKB. | 281 | Q5IFJ9 | 825 | NTRK3_MACFA NT-3 growth factor receptor OS=Ma... | 320 | 0.000000000002 | 74.7 | 26 | 42 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005030; F:neurotrophin receptor activity; IEA:InterPro.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. | 282 | B4LDJ6 | 781 | PLK4_DROVI Serine/threonine-protein kinase PL... | 319 | 0.000000000002 | 74.7 | 26 | 42 | GO:0005814; C:centriole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 283 | Q80ZW0 | 539 | STK35_MOUSE Serine/threonine-protein kinase 3... | 311 | 0.000000000002 | 74.3 | 23 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 284 | A7F0W2 | 951 | ATG1_SCLS1 Serine/threonine-protein kinase AT... | 332 | 0.000000000002 | 74.7 | 25 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 285 | P14238 | 820 | FES_FELCA Tyrosine-protein kinase Fes/Fps OS=... | 311 | 0.000000000002 | 74.7 | 26 | 42 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0031234; C:extrinsic to internal side of plasma membrane; ISS:UniProtKB.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0015630; C:microtubule cytoskeleton; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0034987; F:immunoglobulin receptor binding; ISS:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB. | | | | | | | | | | GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:2000251; P:positive regulation of actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0031116; P:positive regulation of microtubule polymerization; ISS:UniProtKB.::GO:0045639; P:positive regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0030155; P:regulation of cell adhesion; ISS:UniProtKB.::GO:2000145; P:regulation of cell motility; ISS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0043304; P:regulation of mast cell degranulation; ISS:UniProtKB. | 286 | Q0WPH8 | 956 | NEK5_ARATH Serine/threonine-protein kinase Ne... | 311 | 0.000000000002 | 74.7 | 24 | 41 | GO:0055028; C:cortical microtubule; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009913; P:epidermal cell differentiation; IMP:TAIR.::GO:0007017; P:microtubule-based process; IMP:TAIR. | 287 | P80192 | 1104 | M3K9_HUMAN Mitogen-activated protein kinase k... | 265 | 0.000000000002 | 74.7 | 27 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0004706; F:JUN kinase kinase kinase activity; ISS:UniProtKB.::GO:0004708; F:MAP kinase kinase activity; NAS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 288 | Q06187 | 659 | BTK_HUMAN Tyrosine-protein kinase BTK OS=Homo... | 308 | 0.000000000002 | 74.3 | 24 | 42 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0045121; C:membrane raft; IDA:HGNC.::GO:0005634; C:nucleus; TAS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; TAS:HGNC.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB. | | | | | | | | | | GO:0002250; P:adaptive immune response; TAS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042113; P:B cell activation; TAS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; TAS:UniProtKB.::GO:0019722; P:calcium-mediated signaling; TAS:HGNC.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:UniProtKB.::GO:0007498; P:mesoderm development; TAS:ProtInc.::GO:0045579; P:positive regulation of B cell differentiation; TAS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:UniProtKB.::GO:0002902; P:regulation of B cell apoptotic process; TAS:UniProtKB.::GO:0002721; P:regulation of B cell cytokine production; TAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 289 | Q75L42 | 454 | CIPKH_ORYSJ CBL-interacting protein kinase 17... | 256 | 0.000000000002 | 73.9 | 28 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 290 | Q02858 | 1122 | TIE2_MOUSE Angiopoietin-1 receptor OS=Mus mus... | 315 | 0.000000000002 | 74.7 | 29 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IGI:MGI.::GO:0016337; P:cell-cell adhesion; IMP:MGI.::GO:0007160; P:cell-matrix adhesion; IMP:MGI.::GO:0001935; P:endothelial cell proliferation; IMP:UniProtKB.::GO:0060347; P:heart trabecula formation; IMP:UniProtKB.::GO:0030097; P:hemopoiesis; IMP:MGI.::GO:0016525; P:negative regulation of angiogenesis; ISS:UniProtKB.::GO:2000352; P:negative regulation of endothelial cell apoptotic process; IMP:UniProtKB.::GO:0001569; P:patterning of blood vessels; TAS:DFLAT.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0010595; P:positive regulation of endothelial cell migration; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0051894; P:positive regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IGI:MGI.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; ISS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; TAS:DFLAT.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0001936; P:regulation of endothelial cell proliferation; TAS:DFLAT.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; ISS:UniProtKB.::GO:0032526; P:response to retinoic acid; IDA:BHF-UCL.::GO:0002040; P:sprouting angiogenesis; ISS:UniProtKB.::GO:0034446; P:substrate adhesion-dependent cell spreading; ISS:UniProtKB.::GO:0048014; P:Tie receptor signaling pathway; ISS:UniProtKB.::GO:0001570; P:vasculogenesis; IMP:UniProtKB. | 291 | A4K2P5 | 487 | STK4_COLGU Serine/threonine-protein kinase 4 ... | 246 | 0.000000000002 | 73.9 | 25 | 42 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB. | 292 | O70405 | 1051 | ULK1_MOUSE Serine/threonine-protein kinase UL... | 260 | 0.000000000002 | 74.7 | 24 | 40 | GO:0030659; C:cytoplasmic vesicle membrane; IDA:MGI.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0043005; C:neuron projection; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0034045; C:pre-autophagosomal structure membrane; IDA:UniProtKB.::GO:0070969; C:ULK1-ATG13-FIP200 complex; IPI:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0000045; P:autophagic vacuole assembly; IMP:UniProtKB.::GO:0048675; P:axon extension; IMP:MGI.::GO:0021707; P:cerebellar granule cell differentiation; IMP:MGI.::GO:0048671; P:negative regulation of collateral sprouting; IMP:MGI.::GO:0010508; P:positive regulation of autophagy; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0008104; P:protein localization; ISS:UniProtKB.::GO:0021933; P:radial glia guided migration of cerebellar granule cell; IMP:MGI.::GO:0007265; P:Ras protein signal transduction; IDA:MGI.::GO:0031623; P:receptor internalization; IMP:MGI.::GO:0051386; P:regulation of nerve growth factor receptor signaling pathway; IMP:MGI. | 293 | O97143 | 769 | PLK4_DROME Serine/threonine-protein kinase PL... | 310 | 0.000000000002 | 74.3 | 27 | 42 | GO:0005814; C:centriole; IDA:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007099; P:centriole replication; IMP:FlyBase.::GO:0007052; P:mitotic spindle organization; IMP:FlyBase.::GO:0046599; P:regulation of centriole replication; IDA:FlyBase.::GO:0007288; P:sperm axoneme assembly; IMP:FlyBase. | 294 | Q8JH64 | 657 | BTK_CHICK Tyrosine-protein kinase BTK OS=Gall... | 314 | 0.000000000002 | 74.3 | 24 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 295 | Q5A649 | 834 | ATG1_CANAL Serine/threonine-protein kinase AT... | 318 | 0.000000000002 | 74.7 | 24 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 296 | P25323 | 295 | MYLKA_DICDI Myosin light chain kinase A OS=Di... | 323 | 0.000000000002 | 72 | 26 | 41 | GO:0005737; C:cytoplasm; IDA:dictyBase. | | | | | | | | | | GO:0030898; F:actin-dependent ATPase activity; IDA:dictyBase.::GO:0005524; F:ATP binding; IC:dictyBase.::GO:0004687; F:myosin light chain kinase activity; IDA:dictyBase. | | | | | | | | | | GO:0019933; P:cAMP-mediated signaling; IDA:dictyBase.::GO:0019934; P:cGMP-mediated signaling; IDA:dictyBase.::GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0046777; P:protein autophosphorylation; IDA:dictyBase.::GO:0050920; P:regulation of chemotaxis; IMP:dictyBase. | 297 | Q9I9E0 | 898 | TAOK3_CHICK Serine/threonine-protein kinase T... | 323 | 0.000000000002 | 74.7 | 25 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:AgBase. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0000165; P:MAPK cascade; ISS:AgBase.::GO:0046329; P:negative regulation of JNK cascade; ISS:AgBase.::GO:0046330; P:positive regulation of JNK cascade; ISS:AgBase.::GO:0046777; P:protein autophosphorylation; ISS:AgBase. | 298 | Q02763 | 1124 | TIE2_HUMAN Angiopoietin-1 receptor OS=Homo sa... | 315 | 0.000000000002 | 74.7 | 29 | 43 | GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0009925; C:basal plasma membrane; IDA:UniProtKB.::GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0045121; C:membrane raft; IDA:UniProtKB.::GO:0005902; C:microvillus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0060216; P:definitive hemopoiesis; TAS:UniProtKB.::GO:0001935; P:endothelial cell proliferation; ISS:UniProtKB.::GO:0072012; P:glomerulus vasculature development; ISS:UniProtKB.::GO:0060347; P:heart trabecula formation; ISS:UniProtKB.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0016525; P:negative regulation of angiogenesis; IMP:UniProtKB.::GO:2000352; P:negative regulation of endothelial cell apoptotic process; ISS:UniProtKB.::GO:0050728; P:negative regulation of inflammatory response; TAS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:2000251; P:positive regulation of actin cytoskeleton reorganization; IMP:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; IDA:UniProtKB.::GO:0010595; P:positive regulation of endothelial cell migration; IDA:UniProtKB.::GO:0001938; P:positive regulation of endothelial cell proliferation; TAS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.::GO:0051894; P:positive regulation of focal adhesion assembly; IMP:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IMP:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0051259; P:protein oligomerization; IDA:UniProtKB.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IMP:UniProtKB.::GO:0043114; P:regulation of vascular permeability; TAS:UniProtKB.::GO:0002040; P:sprouting angiogenesis; IMP:UniProtKB.::GO:0034446; P:substrate adhesion-dependent cell spreading; IMP:UniProtKB.::GO:0048014; P:Tie receptor signaling pathway; IDA:UniProtKB. | 299 | Q96NX5 | 476 | KCC1G_HUMAN Calcium/calmodulin-dependent prot... | 315 | 0.000000000002 | 73.6 | 26 | 41 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 300 | Q9H2K8 | 898 | TAOK3_HUMAN Serine/threonine-protein kinase T... | 324 | 0.000000000002 | 74.3 | 25 | 40 | GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004860; F:protein kinase inhibitor activity; TAS:ProtInc.::GO:0004674; F:protein serine/threonine kinase activity; IDA:HGNC. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:UniProtKB.::GO:0000165; P:MAPK cascade; IMP:HGNC.::GO:0046329; P:negative regulation of JNK cascade; IDA:HGNC.::GO:0046330; P:positive regulation of JNK cascade; IMP:HGNC.::GO:0046777; P:protein autophosphorylation; IDA:HGNC. | 301 | Q91044 | 827 | NTRK3_CHICK NT-3 growth factor receptor OS=Ga... | 320 | 0.000000000002 | 74.3 | 26 | 42 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005030; F:neurotrophin receptor activity; IEA:InterPro.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. |
