rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
301 | Q8TC12 | 318 | RDH11_HUMAN Retinol dehydrogenase 11 OS=Homo ... | 96 | 0.00000002 | 58.2 | 35 | 50 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0052650; F:NADP-retinol dehydrogenase activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0042574; P:retinal metabolic process; IDA:MGI.::GO:0042572; P:retinol metabolic process; ISS:UniProtKB.::GO:0008202; P:steroid metabolic process; TAS:Reactome. | 302 | O70351 | 261 | HCD2_RAT 3-hydroxyacyl-CoA dehydrogenase type... | 259 | 0.00000002 | 57.4 | 25 | 44 | | | | | | | | | | | GO:0047015; F:3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity; IEA:EC.::GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:EC.::GO:0018454; F:acetoacetyl-CoA reductase activity; IDA:RGD.::GO:0001540; F:beta-amyloid binding; IDA:RGD.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:RGD.::GO:0030331; F:estrogen receptor binding; IPI:RGD.::GO:0042802; F:identical protein binding; IDA:RGD.::GO:0051287; F:NAD binding; IDA:RGD.::GO:0005496; F:steroid binding; IDA:RGD. | | | | | | | | | | GO:0007569; P:cell aging; IEP:RGD.::GO:0033327; P:Leydig cell differentiation; IEP:RGD.::GO:0051289; P:protein homotetramerization; IDA:RGD.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. | 303 | Q9Z2M4 | 292 | DECR2_RAT Peroxisomal 2,4-dienoyl-CoA reducta... | 251 | 0.00000002 | 57.8 | 24 | 47 | GO:0005777; C:peroxisome; IDA:HGNC. | | | | | | | | | | GO:0008670; F:2,4-dienoyl-CoA reductase (NADPH) activity; IDA:RGD.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 304 | Q920P0 | 244 | DCXR_RAT L-xylulose reductase OS=Rattus norve... | 250 | 0.00000002 | 57 | 25 | 42 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050038; F:L-xylulose reductase (NADP+) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; IDA:UniProtKB.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0005997; P:xylulose metabolic process; IDA:UniProtKB. | 305 | Q8U8I2 | 249 | SDH_AGRT5 Serine 3-dehydrogenase OS=Agrobacte... | 232 | 0.00000002 | 57 | 25 | 41 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0031132; F:serine 3-dehydrogenase activity; IEA:EC. | | | | | | | | | | | 306 | O05730 | 284 | VDLC_HELPY Probable short-chain type dehydrog... | 190 | 0.00000002 | 57.4 | 27 | 46 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 307 | Q8VCC1 | 269 | PGDH_MOUSE 15-hydroxyprostaglandin dehydrogen... | 192 | 0.00000002 | 57.4 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0097070; P:ductus arteriosus closure; IMP:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; ISS:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB. | 308 | Q6PKH6 | 230 | DR4L2_HUMAN Dehydrogenase/reductase SDR famil... | 193 | 0.00000003 | 56.6 | 27 | 46 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 309 | O02691 | 261 | HCD2_BOVIN 3-hydroxyacyl-CoA dehydrogenase ty... | 261 | 0.00000003 | 56.6 | 29 | 46 | | | | | | | | | | | GO:0047015; F:3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity; IEA:EC.::GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. | 310 | Q9VXJ0 | 598 | DHB4_DROME Peroxisomal multifunctional enzyme... | 195 | 0.00000003 | 57.4 | 27 | 45 | GO:0005777; C:peroxisome; IC:FlyBase. | | | | | | | | | | GO:0080023; F:3R-hydroxyacyl-CoA dehydratase activity; IDA:FlyBase.::GO:0004300; F:enoyl-CoA hydratase activity; IDA:FlyBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:EC.::GO:0042803; F:protein homodimerization activity; IDA:FlyBase. | | | | | | | | | | GO:0033540; P:fatty acid beta-oxidation using acyl-CoA oxidase; IC:FlyBase. | 311 | Q5E9H7 | 312 | DHB12_BOVIN Estradiol 17-beta-dehydrogenase 1... | 190 | 0.00000004 | 57 | 27 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 312 | Q96NR8 | 316 | RDH12_HUMAN Retinol dehydrogenase 12 OS=Homo ... | 89 | 0.00000005 | 56.6 | 35 | 53 | GO:0005622; C:intracellular; IDA:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0045494; P:photoreceptor cell maintenance; TAS:UniProtKB.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0042572; P:retinol metabolic process; IDA:UniProtKB. | 313 | P54554 | 259 | YQJQ_BACSU Uncharacterized oxidoreductase yqj... | 225 | 0.00000005 | 56.2 | 24 | 46 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 314 | P05707 | 259 | SRLD_ECOLI Sorbitol-6-phosphate 2-dehydrogena... | 257 | 0.00000005 | 56.2 | 23 | 42 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0009010; F:sorbitol-6-phosphate 2-dehydrogenase activity; IEA:EC. | | | | | | | | | | | 315 | Q8NBQ5 | 300 | DHB11_HUMAN Estradiol 17-beta-dehydrogenase 1... | 241 | 0.00000005 | 56.2 | 25 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005811; C:lipid particle; IDA:UniProtKB. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006710; P:androgen catabolic process; IDA:HGNC.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 316 | A5PJJ7 | 316 | S16C6_BOVIN Short-chain dehydrogenase/reducta... | 198 | 0.00000006 | 56.2 | 23 | 44 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 317 | Q49WS9 | 246 | Y1627_STAS1 Uncharacterized oxidoreductase SS... | 148 | 0.00000006 | 55.8 | 26 | 47 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 318 | P31808 | 252 | YCIK_ECOLI Uncharacterized oxidoreductase yci... | 231 | 0.00000007 | 55.8 | 29 | 46 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 319 | Q9NKW1 | 441 | MFEA_DICDI Peroxisomal multifunctional enzyme... | 201 | 0.00000009 | 55.8 | 27 | 45 | GO:0005777; C:peroxisome; TAS:dictyBase. | | | | | | | | | | GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW. | 320 | Q83RE8 | 248 | YDFG_SHIFL NADP-dependent L-serine/L-allo-thr... | 235 | 0.0000001 | 55.1 | 24 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 321 | Q8FHD2 | 248 | YDFG_ECOL6 NADP-dependent L-serine/L-allo-thr... | 235 | 0.0000001 | 55.1 | 24 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 322 | Q9C826 | 285 | ABA2_ARATH Xanthoxin dehydrogenase OS=Arabido... | 263 | 0.0000002 | 55.1 | 25 | 47 | GO:0005829; C:cytosol; IDA:TAIR. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0010301; F:xanthoxin dehydrogenase activity; IDA:TAIR. | | | | | | | | | | GO:0009688; P:abscisic acid biosynthetic process; IMP:TAIR.::GO:0006561; P:proline biosynthetic process; IMP:TAIR.::GO:0010115; P:regulation of abscisic acid biosynthetic process; IMP:TAIR.::GO:0009750; P:response to fructose stimulus; IMP:TAIR.::GO:0009408; P:response to heat; IMP:TAIR.::GO:0009414; P:response to water deprivation; IMP:TAIR.::GO:0010182; P:sugar mediated signaling pathway; TAS:TAIR. | 323 | Q5NVG2 | 300 | DHB11_PONAB Estradiol 17-beta-dehydrogenase 1... | 241 | 0.0000002 | 55.1 | 24 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 324 | Q53GQ0 | 312 | DHB12_HUMAN Estradiol 17-beta-dehydrogenase 1... | 184 | 0.0000002 | 55.1 | 27 | 48 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0035338; P:long-chain fatty-acyl-CoA biosynthetic process; TAS:Reactome.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.::GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome. | 325 | Q9QYF1 | 316 | RDH11_MOUSE Retinol dehydrogenase 11 OS=Mus m... | 89 | 0.0000002 | 55.1 | 35 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0001917; C:photoreceptor inner segment; IDA:MGI. | | | | | | | | | | GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0016062; P:adaptation of rhodopsin mediated signaling; IMP:MGI.::GO:0042572; P:retinol metabolic process; ISS:UniProtKB. | 326 | Q4R5G7 | 312 | DHB12_MACFA Estradiol 17-beta-dehydrogenase 1... | 190 | 0.0000002 | 54.7 | 26 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 327 | Q8X505 | 248 | YDFG_ECO57 NADP-dependent L-serine/L-allo-thr... | 235 | 0.0000002 | 54.3 | 24 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 328 | P37959 | 280 | YUSZ_BACSU Uncharacterized oxidoreductase yus... | 199 | 0.0000002 | 54.7 | 24 | 47 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 329 | A0R518 | 279 | Y6031_MYCS2 Putative short-chain type dehydro... | 276 | 0.0000002 | 54.7 | 25 | 42 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 330 | Q99714 | 261 | HCD2_HUMAN 3-hydroxyacyl-CoA dehydrogenase ty... | 259 | 0.0000002 | 54.3 | 25 | 45 | GO:0005759; C:mitochondrial matrix; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0047015; F:3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity; IEA:EC.::GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; EXP:Reactome.::GO:0008709; F:cholate 7-alpha-dehydrogenase activity; TAS:ProtInc. | | | | | | | | | | GO:0009083; P:branched chain family amino acid catabolic process; TAS:Reactome.::GO:0006629; P:lipid metabolic process; TAS:ProtInc.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. | 331 | B0D8R3 | 338 | MKAR_LACBS 3-ketoacyl-CoA reductase OS=deceiv... | 231 | 0.0000003 | 54.3 | 27 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. |