| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
721 | P28649 | 503 | CP19A_MOUSE Cytochrome P450 19A1 OS=Mus muscu... | 181 | 0.000004 | 53.1 | 25 | 46 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | GO:0008209; P:androgen metabolic process; IMP:MGI.::GO:0060736; P:prostate gland growth; IMP:MGI. | 722 | Q9AXH9 | 499 | KAO1_HORVU Ent-kaurenoic acid oxidase 1 OS=Ho... | 204 | 0.000004 | 53.1 | 25 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 723 | Q9VWR2 | 490 | CP308_DROME Probable cytochrome P450 308a1 OS... | 390 | 0.000004 | 53.1 | 23 | 37 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 724 | P00187 | 516 | CP1A2_RABIT Cytochrome P450 1A2 OS=Oryctolagu... | 180 | 0.000004 | 53.1 | 23 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | | 725 | Q9VGH1 | 520 | CP315_DROME Cytochrome P450 315a1, mitochondr... | 184 | 0.000005 | 52.8 | 24 | 42 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042768; F:ecdysteroid 2-hydroxylase activity; IDA:FlyBase.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0007417; P:central nervous system development; IMP:FlyBase.::GO:0007391; P:dorsal closure; IMP:FlyBase.::GO:0006697; P:ecdysone biosynthetic process; IDA:FlyBase.::GO:0008258; P:head involution; IMP:FlyBase.::GO:0007494; P:midgut development; IMP:FlyBase.::GO:0008045; P:motor axon guidance; IMP:FlyBase. | 726 | Q5QQX7 | 503 | CP19A_CANFA Cytochrome P450 19A1 OS=Canis fam... | 282 | 0.000005 | 52.8 | 22 | 40 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | | 727 | Q6QHT9 | 511 | CP19A_ANGJA Cytochrome P450 19A1 OS=Anguilla ... | 174 | 0.000005 | 52.8 | 24 | 46 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 728 | Q7Z1V1 | 481 | CP51_TRYCC Sterol 14-alpha demethylase OS=Try... | 202 | 0.000006 | 52.4 | 26 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 729 | O35074 | 501 | PTGIS_MOUSE Prostacyclin synthase OS=Mus musc... | 295 | 0.000006 | 52.4 | 21 | 41 | GO:0005901; C:caveola; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:InterPro.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.::GO:0008116; F:prostaglandin-I synthase activity; ISS:UniProtKB. | | | | | | | | | | GO:0071456; P:cellular response to hypoxia; ISS:UniProtKB.::GO:0071347; P:cellular response to interleukin-1; ISS:UniProtKB.::GO:0071354; P:cellular response to interleukin-6; ISS:UniProtKB.::GO:0050728; P:negative regulation of inflammatory response; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0045019; P:negative regulation of nitric oxide biosynthetic process; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0035360; P:positive regulation of peroxisome proliferator activated receptor signaling pathway; ISS:UniProtKB.::GO:0001516; P:prostaglandin biosynthetic process; ISS:UniProtKB. | 730 | P11511 | 503 | CP19A_HUMAN Cytochrome P450 19A1 OS=Homo sapi... | 188 | 0.000006 | 52.4 | 23 | 44 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005624; C:membrane fraction; TAS:ProtInc. | | | | | | | | | | GO:0070330; F:aromatase activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0020037; F:heme binding; IDA:UniProtKB.::GO:0019825; F:oxygen binding; TAS:ProtInc. | | | | | | | | | | GO:0006703; P:estrogen biosynthetic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 731 | Q8CIM7 | 500 | CP2DQ_MOUSE Cytochrome P450 2D26 OS=Mus muscu... | 205 | 0.000007 | 52.4 | 24 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 732 | Q96SQ9 | 504 | CP2S1_HUMAN Cytochrome P450 2S1 OS=Homo sapie... | 179 | 0.000008 | 52.4 | 26 | 42 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 733 | P93846 | 492 | CP51_SORBI Obtusifoliol 14-alpha demethylase ... | 194 | 0.000008 | 52 | 24 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 734 | P00186 | 513 | CP1A2_MOUSE Cytochrome P450 1A2 OS=Mus muscul... | 173 | 0.000008 | 52 | 24 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:MGI. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | GO:0045333; P:cellular respiration; IMP:MGI.::GO:0071276; P:cellular response to cadmium ion; IDA:MGI.::GO:0018894; P:dibenzo-p-dioxin metabolic process; IMP:MGI.::GO:0050665; P:hydrogen peroxide biosynthetic process; IMP:MGI.::GO:0030324; P:lung development; IMP:MGI.::GO:0006778; P:porphyrin-containing compound metabolic process; IMP:MGI.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0010468; P:regulation of gene expression; IMP:MGI. | 735 | P22443 | 508 | CP19A_RAT Cytochrome P450 19A1 OS=Rattus norv... | 177 | 0.00001 | 51.6 | 24 | 45 | GO:0005829; C:cytosol; IDA:RGD.::GO:0043197; C:dendritic spine; IDA:RGD.::GO:0005783; C:endoplasmic reticulum; IDA:RGD.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0008021; C:synaptic vesicle; IDA:RGD.::GO:0043195; C:terminal button; IDA:RGD. | | | | | | | | | | GO:0070330; F:aromatase activity; IDA:RGD.::GO:0009055; F:electron carrier activity; IEA:InterPro. | | | | | | | | | | GO:0030325; P:adrenal gland development; IEP:RGD.::GO:0008209; P:androgen metabolic process; IMP:RGD.::GO:0008206; P:bile acid metabolic process; IEP:RGD.::GO:0018879; P:biphenyl metabolic process; IEP:RGD.::GO:0060348; P:bone development; IEP:RGD.::GO:0044344; P:cellular response to fibroblast growth factor stimulus; IEP:RGD.::GO:0071372; P:cellular response to follicle-stimulating hormone stimulus; IEP:RGD.::GO:0071333; P:cellular response to glucose stimulus; IEP:RGD.::GO:0071464; P:cellular response to hydrostatic pressure; IEP:RGD.::GO:0018894; P:dibenzo-p-dioxin metabolic process; IEP:RGD.::GO:0006703; P:estrogen biosynthetic process; IDA:RGD.::GO:0030851; P:granulocyte differentiation; IEP:RGD.::GO:0021766; P:hippocampus development; IEP:RGD.::GO:0021854; P:hypothalamus development; IEP:RGD.::GO:0008584; P:male gonad development; IEP:RGD.::GO:0030186; P:melatonin metabolic process; IEP:RGD.::GO:0018963; P:phthalate metabolic process; IEP:RGD.::GO:0042448; P:progesterone metabolic process; IEP:RGD.::GO:0050803; P:regulation of synapse structure and activity; IMP:RGD.::GO:0010164; P:response to cesium ion; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0009635; P:response to herbicide; IEP:RGD.::GO:0010212; P:response to ionizing radiation; IEP:RGD.::GO:0043278; P:response to morphine; IEP:RGD.::GO:0033574; P:response to testosterone stimulus; IEP:RGD. | 736 | P98181 | 515 | CP1A1_PAGMA Cytochrome P450 1A1 OS=Pagrus maj... | 174 | 0.00001 | 51.6 | 24 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 737 | Q5RBQ1 | 516 | CP1A2_PONAB Cytochrome P450 1A2 OS=Pongo abel... | 180 | 0.00001 | 51.6 | 24 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | | 738 | Q701P2 | 525 | KO1_GIBIN Ent-kaurene oxidase OS=proliferatum... | 204 | 0.00001 | 51.6 | 25 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0052617; F:ent-kaur-16-en-19-al oxidase activity; IEA:EC.::GO:0052616; F:ent-kaur-16-en-19-ol oxidase activity; IEA:EC.::GO:0052615; F:ent-kaurene oxidase activity; IEA:EC.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0010241; P:ent-kaurene oxidation to kaurenoic acid; IEA:EC. | 739 | Q29605 | 503 | CP19A_RABIT Cytochrome P450 19A1 OS=Oryctolag... | 241 | 0.00001 | 51.6 | 22 | 41 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro. | | | | | | | | | | | 740 | P63717 | 441 | CP138_MYCTU Putative cytochrome P450 138 OS=M... | 466 | 0.00001 | 51.2 | 23 | 39 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 741 | P63718 | 441 | CP138_MYCBO Putative cytochrome P450 138 OS=M... | 466 | 0.00001 | 51.2 | 23 | 39 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 742 | O77810 | 516 | CP1A2_CALJA Cytochrome P450 1A2 OS=Callithrix... | 173 | 0.00001 | 51.6 | 23 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | | 743 | P24457 | 505 | CP2DB_MOUSE Cytochrome P450 2D11 OS=Mus muscu... | 348 | 0.00002 | 51.2 | 21 | 37 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 744 | Q69FB6 | 503 | CP19A_LAGAC Cytochrome P450 19A1 OS=Lagenorhy... | 177 | 0.00002 | 51.2 | 24 | 46 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | | 745 | Q9M7B8 | 542 | C79D1_MANES Valine N-monooxygenase 1 OS=Manih... | 172 | 0.00002 | 51.2 | 21 | 44 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IDA:UniProtKB.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0019756; P:cyanogenic glycoside biosynthetic process; IDA:UniProtKB. | 746 | P22680 | 504 | CP7A1_HUMAN Cholesterol 7-alpha-monooxygenase... | 199 | 0.00002 | 51.2 | 25 | 45 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; ISS:UniProtKB. | | | | | | | | | | GO:0008123; F:cholesterol 7-alpha-monooxygenase activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0071397; P:cellular response to cholesterol; ISS:UniProtKB.::GO:0071333; P:cellular response to glucose stimulus; IDA:UniProtKB.::GO:0006707; P:cholesterol catabolic process; ISS:UniProtKB.::GO:0042632; P:cholesterol homeostasis; ISS:UniProtKB.::GO:0070857; P:regulation of bile acid biosynthetic process; IDA:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 747 | Q9M7B7 | 541 | C79D2_MANES Valine N-monooxygenase 2 OS=Manih... | 191 | 0.00002 | 50.8 | 21 | 42 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IDA:UniProtKB.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0019756; P:cyanogenic glycoside biosynthetic process; IDA:UniProtKB. | 748 | Q9VG17 | 510 | CP304_DROME Probable cytochrome P450 304a1 OS... | 165 | 0.00002 | 50.8 | 28 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 749 | P54781 | 538 | ERG5_YEAST Cytochrome P450 61 OS=Saccharomyce... | 135 | 0.00002 | 50.8 | 30 | 43 | GO:0005783; C:endoplasmic reticulum; IDA:SGD. | | | | | | | | | | GO:0000249; F:C-22 sterol desaturase activity; IDA:SGD.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:InterPro. | | | | | | | | | | GO:0006696; P:ergosterol biosynthetic process; IDA:SGD. | 750 | Q7YRB2 | 501 | CP8B1_PIG 5-beta-cholestane-3-alpha,7-alpha-d... | 198 | 0.00002 | 50.4 | 26 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0033779; F:5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 751 | Q43246 | 519 | C88A1_MAIZE Cytochrome P450 88A1 OS=Zea mays ... | 183 | 0.00003 | 50.4 | 25 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | |
