rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
661 | P10635 | 497 | CP2D6_HUMAN Cytochrome P450 2D6 OS=Homo sapie... | 237 | 0.0000003 | 57 | 24 | 40 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IDA:BHF-UCL.::GO:0005739; C:mitochondrion; IDA:BHF-UCL. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0008144; F:drug binding; IDA:BHF-UCL.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IDA:UniProtKB. | | | | | | | | | | GO:0009822; P:alkaloid catabolic process; IDA:BHF-UCL.::GO:0009804; P:coumarin metabolic process; IDA:BHF-UCL.::GO:0042737; P:drug catabolic process; IDA:BHF-UCL.::GO:0033076; P:isoquinoline alkaloid metabolic process; IDA:BHF-UCL.::GO:0016098; P:monoterpenoid metabolic process; IDA:BHF-UCL.::GO:0051100; P:negative regulation of binding; IDA:BHF-UCL.::GO:0090350; P:negative regulation of cellular organofluorine metabolic process; IDA:BHF-UCL.::GO:0070989; P:oxidative demethylation; IDA:BHF-UCL.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0008202; P:steroid metabolic process; IMP:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:BHF-UCL. | 662 | Q6J540 | 536 | C79D4_LOTJA Isoleucine N-monooxygenase 2 OS=L... | 239 | 0.0000003 | 57 | 24 | 40 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IDA:UniProtKB.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0019756; P:cyanogenic glycoside biosynthetic process; IDA:UniProtKB. | 663 | O42145 | 509 | C19AA_DANRE Cytochrome P450 19A1a OS=Danio re... | 229 | 0.0000003 | 57 | 24 | 45 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 664 | Q54WB9 | 519 | C513D_DICDI Probable cytochrome P450 513D1 OS... | 476 | 0.0000003 | 56.6 | 19 | 36 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 665 | Q6GUR1 | 512 | CP1A1_MACMU Cytochrome P450 1A1 OS=Macaca mul... | 345 | 0.0000003 | 56.6 | 21 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 666 | P33616 | 512 | CP1A1_MACFA Cytochrome P450 1A1 OS=Macaca fas... | 166 | 0.0000003 | 56.6 | 25 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 667 | Q55BU9 | 492 | C5133_DICDI Probable cytochrome P450 513A3 OS... | 188 | 0.0000004 | 56.6 | 24 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 668 | Q93ZB2 | 509 | KO1_ARATH Ent-kaurene oxidase, chloroplastic ... | 175 | 0.0000004 | 56.6 | 24 | 42 | GO:0009707; C:chloroplast outer membrane; IDA:TAIR.::GO:0005783; C:endoplasmic reticulum; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0052617; F:ent-kaur-16-en-19-al oxidase activity; IEA:EC.::GO:0052616; F:ent-kaur-16-en-19-ol oxidase activity; IEA:EC.::GO:0052615; F:ent-kaurene oxidase activity; IEA:EC.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0010241; P:ent-kaurene oxidation to kaurenoic acid; IMP:TAIR.::GO:0009740; P:gibberellic acid mediated signaling pathway; TAS:TAIR.::GO:0009686; P:gibberellin biosynthetic process; IDA:TAIR. | 669 | P79761 | 528 | CP1A5_CHICK Cytochrome P450 1A5 OS=Gallus gal... | 359 | 0.0000004 | 56.6 | 22 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 670 | Q92109 | 522 | CP1A3_ONCMY Cytochrome P450 1A3 OS=Oncorhynch... | 166 | 0.0000004 | 56.6 | 27 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 671 | Q9V557 | 520 | CP4P2_DROME Probable cytochrome P450 4p2 OS=D... | 269 | 0.0000004 | 56.2 | 22 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 672 | Q554S4 | 530 | C519A_DICDI Probable cytochrome P450 519A1 OS... | 244 | 0.0000004 | 56.6 | 23 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 673 | P79304 | 501 | CP193_PIG Cytochrome P450 19 type III OS=Sus ... | 241 | 0.0000004 | 56.2 | 25 | 42 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 674 | P30100 | 500 | C11B3_RAT Cytochrome P450 11B3, mitochondrial... | 189 | 0.0000005 | 56.2 | 25 | 43 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047783; F:corticosterone 18-monooxygenase activity; IDA:RGD.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004507; F:steroid 11-beta-monooxygenase activity; IDA:RGD. | | | | | | | | | | GO:0030325; P:adrenal gland development; IEP:RGD.::GO:0043434; P:response to peptide hormone stimulus; IEP:RGD. | 675 | P79430 | 503 | CP192_PIG Cytochrome P450 19 type II OS=Sus s... | 344 | 0.0000005 | 56.2 | 22 | 40 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 676 | P49602 | 561 | CP51_USTMA Lanosterol 14-alpha demethylase OS... | 265 | 0.0000005 | 55.8 | 28 | 41 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 677 | P79202 | 520 | CP11A_SHEEP Cholesterol side-chain cleavage e... | 371 | 0.0000006 | 55.8 | 24 | 42 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008386; F:cholesterol monooxygenase (side-chain-cleaving) activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 678 | P30099 | 510 | C11B2_RAT Cytochrome P450 11B2, mitochondrial... | 189 | 0.0000006 | 55.8 | 25 | 43 | GO:0030425; C:dendrite; IDA:RGD.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047783; F:corticosterone 18-monooxygenase activity; IDA:RGD.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004507; F:steroid 11-beta-monooxygenase activity; IDA:RGD. | | | | | | | | | | GO:0032342; P:aldosterone biosynthetic process; IDA:RGD.::GO:0071260; P:cellular response to mechanical stimulus; IEP:RGD.::GO:0031670; P:cellular response to nutrient; IEP:RGD.::GO:0071375; P:cellular response to peptide hormone stimulus; IEP:RGD.::GO:0051365; P:cellular response to potassium ion starvation; IEP:RGD.::GO:0006704; P:glucocorticoid biosynthetic process; IDA:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IEP:RGD. | 679 | P10634 | 500 | CP2DQ_RAT Cytochrome P450 2D26 OS=Rattus norv... | 178 | 0.0000006 | 55.8 | 25 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0007565; P:female pregnancy; IEP:RGD.::GO:0042493; P:response to drug; IDA:RGD. | 680 | Q8L7D5 | 477 | THAH_ARATH Cytochrome P450 708A2 OS=Arabidops... | 187 | 0.0000007 | 55.5 | 27 | 43 | GO:0005783; C:endoplasmic reticulum; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.::GO:0080014; F:thalianol hydroxylase activity; IMP:TAIR. | | | | | | | | | | GO:0048364; P:root development; IMP:TAIR.::GO:0080003; P:thalianol metabolic process; IMP:TAIR. | 681 | Q12664 | 515 | CP51_PENIT Eburicol 14-alpha-demethylase OS=P... | 184 | 0.0000007 | 55.5 | 25 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 682 | Q50EK0 | 497 | C16B2_PICSI Cytochrome P450 716B2 OS=Picea si... | 377 | 0.0000007 | 55.5 | 23 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 683 | Q95078 | 538 | CP18A_DROME Cytochrome P450 18a1 OS=Drosophil... | 178 | 0.0000008 | 55.5 | 30 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.::GO:0008395; F:steroid hydroxylase activity; IDA:FlyBase. | | | | | | | | | | GO:0046344; P:ecdysteroid catabolic process; IMP:FlyBase.::GO:0007480; P:imaginal disc-derived leg morphogenesis; IMP:FlyBase.::GO:0035210; P:prepupal development; IMP:FlyBase.::GO:0035074; P:pupation; IMP:FlyBase. | 684 | P11714 | 504 | CP2D9_MOUSE Cytochrome P450 2D9 OS=Mus muscul... | 512 | 0.0000008 | 55.5 | 21 | 37 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:MGI. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 685 | Q3LFU0 | 516 | CP1A1_BALAC Cytochrome P450 1A1 OS=Balaenopte... | 176 | 0.0000008 | 55.5 | 25 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 686 | Q9DBX6 | 501 | CP2S1_MOUSE Cytochrome P450 2S1 OS=Mus muscul... | 211 | 0.0000009 | 55.1 | 27 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 687 | P46194 | 503 | CP19A_BOVIN Cytochrome P450 19A1 OS=Bos tauru... | 241 | 0.0000009 | 55.1 | 24 | 42 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; ISS:UniProtKB. | | | | | | | | | | | 688 | Q29488 | 497 | CP2DH_MACFA Cytochrome P450 2D17 OS=Macaca fa... | 237 | 0.0000009 | 55.1 | 24 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 689 | P79760 | 530 | CP1A4_CHICK Cytochrome P450 1A4 OS=Gallus gal... | 173 | 0.0000009 | 55.1 | 24 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 690 | O64989 | 513 | C90B1_ARATH Cytochrome P450 90B1 OS=Arabidops... | 210 | 0.000001 | 55.1 | 26 | 42 | GO:0005783; C:endoplasmic reticulum; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.::GO:0010012; F:steroid 22-alpha hydroxylase activity; IDA:TAIR. | | | | | | | | | | GO:0016132; P:brassinosteroid biosynthetic process; IMP:TAIR.::GO:0009867; P:jasmonic acid mediated signaling pathway; IGI:TAIR.::GO:0010358; P:leaf shaping; IMP:TAIR.::GO:0009741; P:response to brassinosteroid stimulus; IEP:TAIR.::GO:0009826; P:unidimensional cell growth; IMP:TAIR. | 691 | O46658 | 500 | CP2DP_PIG Vitamin D(3) 25-hydroxylase OS=Sus ... | 249 | 0.000001 | 55.1 | 25 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047749; F:cholestanetriol 26-monooxygenase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro. | | | | | | | | | | |