| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | O08528 | 917 | HXK2_MOUSE Hexokinase-2 OS=Mus musculus (Mous... | 416 | 4e-31 | 132 | 27 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IDA:MGI. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0046324; P:regulation of glucose import; IMP:MGI. | 32 | P05708 | 918 | HXK1_RAT Hexokinase-1 OS=Rattus norvegicus (R... | 423 | 1e-26 | 119 | 26 | 43 | GO:0005901; C:caveola; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0043234; C:protein complex; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0016887; F:ATPase activity; IC:RGD.::GO:0004340; F:glucokinase activity; IDA:RGD.::GO:0005536; F:glucose binding; IDA:RGD.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0004672; F:protein kinase activity; IDA:RGD. | | | | | | | | | | GO:0006096; P:glycolysis; IDA:RGD.::GO:0043066; P:negative regulation of apoptotic process; IMP:RGD.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:RGD.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:RGD.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0010359; P:regulation of anion channel activity; IDA:RGD. | 33 | P50521 | 455 | HXK2_SCHPO Hexokinase-2 OS=Schizosaccharomyce... | 463 | 3e-32 | 132 | 26 | 44 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008865; F:fructokinase activity; IDA:PomBase.::GO:0004340; F:glucokinase activity; IDA:PomBase.::GO:0019158; F:mannokinase activity; IDA:PomBase. | | | | | | | | | | GO:0006002; P:fructose 6-phosphate metabolic process; IDA:PomBase.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006013; P:mannose metabolic process; IDA:PomBase. | 34 | P27881 | 917 | HXK2_RAT Hexokinase-2 OS=Rattus norvegicus (R... | 416 | 3e-31 | 132 | 27 | 45 | GO:0005741; C:mitochondrial outer membrane; TAS:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0005536; F:glucose binding; IDA:RGD.::GO:0004396; F:hexokinase activity; IDA:RGD. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0007595; P:lactation; IEP:RGD. | 35 | P17712 | 465 | HXK4_RAT Glucokinase OS=Rattus norvegicus (Ra... | 477 | 9e-32 | 131 | 27 | 44 | GO:0044448; C:cell cortex part; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0005654; C:nucleoplasm; IDA:RGD.::GO:0030141; C:secretory granule; IDA:RGD. | | | | | | | | | | GO:0043531; F:ADP binding; IDA:RGD.::GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004340; F:glucokinase activity; ISS:UniProtKB.::GO:0005536; F:glucose binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:RGD.::GO:0019903; F:protein phosphatase binding; IPI:RGD. | | | | | | | | | | GO:0001678; P:cellular glucose homeostasis; IMP:RGD.::GO:0042149; P:cellular response to glucose starvation; IMP:RGD.::GO:0032869; P:cellular response to insulin stimulus; IDA:BHF-UCL.::GO:0044320; P:cellular response to leptin stimulus; IDA:BHF-UCL.::GO:0051594; P:detection of glucose; ISS:UniProtKB.::GO:0007204; P:elevation of cytosolic calcium ion concentration; IDA:RGD.::GO:0006003; P:fructose 2,6-bisphosphate metabolic process; IDA:RGD.::GO:0005978; P:glycogen biosynthetic process; IDA:RGD.::GO:0006096; P:glycolysis; IDA:RGD.::GO:0032811; P:negative regulation of epinephrine secretion; IMP:RGD.::GO:0045721; P:negative regulation of gluconeogenesis; ISS:UniProtKB.::GO:0045725; P:positive regulation of glycogen biosynthetic process; ISS:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; IDA:RGD.::GO:0032024; P:positive regulation of insulin secretion; ISS:UniProtKB.::GO:0042327; P:positive regulation of phosphorylation; IDA:RGD.::GO:0019932; P:second-messenger-mediated signaling; IDA:RGD. | 36 | Q1W674 | 917 | HXK2_PIG Hexokinase-2 OS=Sus scrofa (Pig). GN... | 489 | 4e-31 | 132 | 26 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 37 | P52792 | 465 | HXK4_MOUSE Glucokinase OS=Mus musculus (Mouse... | 478 | 1e-31 | 131 | 28 | 44 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004340; F:glucokinase activity; ISS:UniProtKB.::GO:0005536; F:glucose binding; ISS:UniProtKB. | | | | | | | | | | GO:0070509; P:calcium ion import; IMP:UniProtKB.::GO:0001678; P:cellular glucose homeostasis; IMP:MGI.::GO:0051594; P:detection of glucose; ISS:UniProtKB.::GO:0031018; P:endocrine pancreas development; TAS:Reactome.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006739; P:NADP metabolic process; IMP:MGI.::GO:0045721; P:negative regulation of gluconeogenesis; ISS:UniProtKB.::GO:0045725; P:positive regulation of glycogen biosynthetic process; ISS:UniProtKB.::GO:0032024; P:positive regulation of insulin secretion; IMP:UniProtKB.::GO:0043266; P:regulation of potassium ion transport; IMP:MGI. | 38 | P52789 | 917 | HXK2_HUMAN Hexokinase-2 OS=Homo sapiens (Huma... | 516 | 2e-31 | 133 | 25 | 44 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005741; C:mitochondrial outer membrane; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; TAS:ProtInc. | | | | | | | | | | GO:0008637; P:apoptotic mitochondrial changes; IDA:MGI.::GO:0015758; P:glucose transport; TAS:Reactome.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0055085; P:transmembrane transport; TAS:Reactome. | 39 | A2PYL6 | 917 | HXK2_HORSE Hexokinase-2 OS=Equus caballus (Ho... | 492 | 1e-29 | 127 | 25 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 40 | A2PYL7 | 917 | HXK2_EQUZE Hexokinase-2 OS=Equus zebra (Mount... | 492 | 1e-29 | 127 | 25 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 41 | A2PYL8 | 917 | HXK2_EQUGR Hexokinase-2 OS=Equus grevyi (Grev... | 492 | 1e-29 | 127 | 25 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 42 | P27926 | 924 | HXK3_RAT Hexokinase-3 OS=Rattus norvegicus (R... | 378 | 7e-24 | 110 | 28 | 45 | GO:0043234; C:protein complex; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; IPI:RGD.::GO:0004396; F:hexokinase activity; IDA:RGD.::GO:0042562; F:hormone binding; IPI:RGD. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 43 | P35557 | 465 | HXK4_HUMAN Glucokinase OS=Homo sapiens (Human... | 474 | 3e-31 | 129 | 27 | 44 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004340; F:glucokinase activity; IDA:UniProtKB.::GO:0005536; F:glucose binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0032869; P:cellular response to insulin stimulus; ISS:BHF-UCL.::GO:0044320; P:cellular response to leptin stimulus; ISS:BHF-UCL.::GO:0051594; P:detection of glucose; IMP:UniProtKB.::GO:0031018; P:endocrine pancreas development; TAS:Reactome.::GO:0042593; P:glucose homeostasis; IMP:UniProtKB.::GO:0015758; P:glucose transport; TAS:Reactome.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0045721; P:negative regulation of gluconeogenesis; IMP:UniProtKB.::GO:0045725; P:positive regulation of glycogen biosynthetic process; IMP:UniProtKB.::GO:0032024; P:positive regulation of insulin secretion; IMP:UniProtKB.::GO:0010827; P:regulation of glucose transport; TAS:Reactome.::GO:0006110; P:regulation of glycolysis; NAS:BHF-UCL.::GO:0055085; P:transmembrane transport; TAS:Reactome. | 44 | P80581 | 490 | HXK_EMENI Hexokinase OS=194 / M139) (Aspergil... | 423 | 1e-30 | 128 | 26 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 45 | Q9LPS1 | 498 | HXK3_ARATH Hexokinase-3 OS=Arabidopsis thalia... | 360 | 2e-30 | 128 | 28 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0009536; C:plastid; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR. | 46 | Q3TRM8 | 922 | HXK3_MOUSE Hexokinase-3 OS=Mus musculus (Mous... | 296 | 2e-20 | 99.4 | 30 | 45 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 47 | P52790 | 923 | HXK3_HUMAN Hexokinase-3 OS=Homo sapiens (Huma... | 311 | 7e-21 | 100 | 30 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; NAS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0004396; F:hexokinase activity; NAS:UniProtKB. | | | | | | | | | | GO:0015758; P:glucose transport; TAS:Reactome.::GO:0006096; P:glycolysis; NAS:UniProtKB.::GO:0055085; P:transmembrane transport; TAS:Reactome. | 48 | Q56XE8 | 502 | HXK4_ARATH Hexokinase-4 OS=Arabidopsis thalia... | 312 | 5e-29 | 124 | 28 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 49 | P04806 | 485 | HXKA_YEAST Hexokinase-1 OS=Saccharomyces cere... | 471 | 2e-28 | 122 | 26 | 44 | GO:0005829; C:cytosol; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IDA:SGD. | | | | | | | | | | GO:0032445; P:fructose import; IGI:SGD.::GO:0006000; P:fructose metabolic process; IMP:SGD.::GO:0006096; P:glycolysis; IDA:SGD.::GO:0006013; P:mannose metabolic process; IDA:SGD. | 50 | Q6CUZ3 | 481 | HXKG_KLULA Glucokinase-1 OS=1267 / NRRL Y-114... | 426 | 3e-28 | 121 | 27 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004340; F:glucokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 51 | Q8LH82 | 498 | HXK1_ORYSJ Hexokinase-1 OS=Oryza sativa subsp... | 315 | 7e-26 | 114 | 31 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 52 | Q1WM15 | 458 | HXK8_ORYSJ Hexokinase-8 OS=Oryza sativa subsp... | 317 | 9e-26 | 114 | 29 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 53 | Q2KNB4 | 500 | HXK3_ORYSJ Hexokinase-3 OS=Oryza sativa subsp... | 416 | 3e-25 | 112 | 26 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 54 | Q969A8 | 468 | HXK_TOXGO Hexokinase OS=Toxoplasma gondii. GN... | 368 | 5e-25 | 111 | 29 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 55 | Q9NFT9 | 465 | HXK1_DROME Hexokinase type 1 OS=Drosophila me... | 375 | 2e-20 | 98.2 | 26 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 56 | Q2KNB5 | 504 | HXK10_ORYSJ Hexokinase-10 OS=Oryza sativa sub... | 312 | 3e-20 | 97.8 | 27 | 47 | GO:0009707; C:chloroplast outer membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 57 | O64390 | 498 | HXK1_SOLTU Hexokinase-1 OS=Solanum tuberosum ... | 402 | 8e-20 | 96.3 | 26 | 42 | GO:0009707; C:chloroplast outer membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 58 | Q02155 | 493 | HXK_PLAFA Hexokinase OS=Plasmodium falciparum... | 376 | 3e-19 | 94.4 | 26 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 59 | Q9T071 | 493 | HXKL2_ARATH Probable hexokinase-like 2 protei... | 311 | 0.00000000000008 | 77.8 | 25 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005739; C:mitochondrion; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0006974; P:response to DNA damage stimulus; IEP:TAIR.::GO:0009408; P:response to heat; IEP:TAIR.::GO:0006979; P:response to oxidative stress; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.::GO:0010224; P:response to UV-B; IEP:TAIR.::GO:0009414; P:response to water deprivation; IEP:TAIR. | 60 | Q06204 | 433 | YL446_YEAST Putative hexokinase YLR446W OS=Sa... | 282 | 0.000000004 | 62.4 | 24 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC. | | | | | | | | | | GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 61 | C1GXJ4 | 523 | MMM1_PARBA Maintenance of mitochondrial morph... | 116 | 6.2 | 33.5 | 29 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | |
