rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | P14061 | 328 | DHB1_HUMAN Estradiol 17-beta-dehydrogenase 1 ... | 188 | 7e-16 | 79.7 | 35 | 53 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; TAS:Reactome.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006703; P:estrogen biosynthetic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 62 | P51976 | 406 | DHI2_RABIT Corticosteroid 11-beta-dehydrogena... | 197 | 7e-16 | 80.5 | 31 | 49 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 63 | Q5HKG6 | 257 | BUTA_STAEQ Diacetyl reductase [(S)-acetoin fo... | 189 | 7e-16 | 78.6 | 31 | 48 | | | | | | | | | | | GO:0052588; F:diacetyl reductase ((S)-acetoin forming) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045150; P:acetoin catabolic process; IEA:InterPro. | 64 | P37059 | 387 | DHB2_HUMAN Estradiol 17-beta-dehydrogenase 2 ... | 207 | 7e-16 | 80.1 | 33 | 47 | GO:0005789; C:endoplasmic reticulum membrane; TAS:ProtInc.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; TAS:BHF-UCL.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IDA:UniProtKB. | | | | | | | | | | GO:0032526; P:response to retinoic acid; IDA:BHF-UCL. | 65 | Q9Y394 | 339 | DHRS7_HUMAN Dehydrogenase/reductase SDR famil... | 190 | 8e-16 | 79.3 | 31 | 54 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 66 | Q9X248 | 246 | FABG_THEMA 3-oxoacyl-[acyl-carrier-protein] r... | 217 | 9e-16 | 78.2 | 32 | 50 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.] | 67 | Q1JP75 | 244 | DCXR_BOVIN L-xylulose reductase OS=Bos taurus... | 239 | 0.000000000000001 | 77.8 | 31 | 48 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050038; F:L-xylulose reductase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW. | 68 | P54554 | 259 | YQJQ_BACSU Uncharacterized oxidoreductase yqj... | 194 | 0.000000000000001 | 77.8 | 30 | 50 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 69 | Q7Z4W1 | 244 | DCXR_HUMAN L-xylulose reductase OS=Homo sapie... | 226 | 0.000000000000001 | 77.8 | 31 | 51 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050038; F:L-xylulose reductase (NADP+) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB. | | | | | | | | | | GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; IDA:UniProtKB.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0005997; P:xylulose metabolic process; IDA:UniProtKB. | 70 | Q5ZJZ5 | 339 | BDH_CHICK D-beta-hydroxybutyrate dehydrogenas... | 198 | 0.000000000000001 | 79 | 29 | 49 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003858; F:3-hydroxybutyrate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 71 | Q9NYR8 | 311 | RDH8_HUMAN Retinol dehydrogenase 8 OS=Homo sa... | 226 | 0.000000000000001 | 78.6 | 30 | 50 | GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:InterPro.::GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; TAS:ProtInc. | | | | | | | | | | GO:0006703; P:estrogen biosynthetic process; IEA:InterPro.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; TAS:ProtInc. | 72 | Q6GDV6 | 231 | Y2567_STAAR Uncharacterized oxidoreductase SA... | 199 | 0.000000000000002 | 77 | 28 | 51 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 73 | Q4A054 | 234 | Y0419_STAS1 Uncharacterized oxidoreductase SS... | 185 | 0.000000000000002 | 76.6 | 30 | 53 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 74 | Q8VD48 | 319 | DHRS9_RAT Dehydrogenase/reductase SDR family ... | 194 | 0.000000000000002 | 77.8 | 34 | 49 | GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0005792; C:microsome; ISS:UniProtKB. | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB.::GO:0047035; F:testosterone dehydrogenase (NAD+) activity; ISS:UniProtKB. | | | | | | | | | | GO:0042904; P:9-cis-retinoic acid biosynthetic process; ISS:UniProtKB. | 75 | Q27979 | 318 | RDH1_BOVIN 11-cis retinol dehydrogenase OS=Bo... | 188 | 0.000000000000002 | 77.8 | 38 | 51 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 76 | Q48436 | 256 | BUDC_KLEPN Diacetyl reductase [(S)-acetoin fo... | 219 | 0.000000000000003 | 77 | 31 | 47 | | | | | | | | | | | GO:0052588; F:diacetyl reductase ((S)-acetoin forming) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045150; P:acetoin catabolic process; IEA:InterPro. | 77 | Q29529 | 244 | CBR2_PIG Carbonyl reductase [NADPH] 2 OS=Sus ... | 171 | 0.000000000000003 | 76.6 | 31 | 53 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 78 | Q8CQD2 | 257 | BUTA_STAES Diacetyl reductase [(S)-acetoin fo... | 189 | 0.000000000000003 | 76.6 | 30 | 48 | | | | | | | | | | | GO:0052588; F:diacetyl reductase ((S)-acetoin forming) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045150; P:acetoin catabolic process; IEA:InterPro. | 79 | Q3T0R4 | 325 | DRS7B_BOVIN Dehydrogenase/reductase SDR famil... | 208 | 0.000000000000004 | 77.4 | 28 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 80 | Q58NB6 | 319 | DHRS9_MOUSE Dehydrogenase/reductase SDR famil... | 194 | 0.000000000000004 | 77.4 | 35 | 48 | GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0005792; C:microsome; ISS:UniProtKB. | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB.::GO:0047035; F:testosterone dehydrogenase (NAD+) activity; ISS:UniProtKB. | | | | | | | | | | GO:0042904; P:9-cis-retinoic acid biosynthetic process; ISS:UniProtKB. | 81 | Q9N126 | 312 | RDH8_BOVIN Retinol dehydrogenase 8 OS=Bos tau... | 250 | 0.000000000000004 | 77 | 29 | 49 | GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:InterPro.::GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006703; P:estrogen biosynthetic process; IEA:InterPro.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 82 | P14802 | 238 | YOXD_BACSU Uncharacterized oxidoreductase yox... | 152 | 0.000000000000005 | 75.9 | 34 | 52 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 83 | Q8HYR6 | 319 | DHRS9_BOVIN Dehydrogenase/reductase SDR famil... | 241 | 0.000000000000005 | 77 | 31 | 46 | GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0005792; C:microsome; ISS:UniProtKB. | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB.::GO:0047035; F:testosterone dehydrogenase (NAD+) activity; ISS:UniProtKB. | | | | | | | | | | GO:0042904; P:9-cis-retinoic acid biosynthetic process; ISS:UniProtKB. | 84 | Q04520 | 241 | BUDC_RAOTE Diacetyl reductase [(S)-acetoin fo... | 239 | 0.000000000000006 | 75.5 | 30 | 45 | | | | | | | | | | | GO:0052588; F:diacetyl reductase ((S)-acetoin forming) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045150; P:acetoin catabolic process; IEA:InterPro. | 85 | Q49117 | 248 | Y182_METEA Uncharacterized oxidoreductase Mex... | 104 | 0.000000000000007 | 75.5 | 41 | 57 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 86 | Q49WS9 | 246 | Y1627_STAS1 Uncharacterized oxidoreductase SS... | 194 | 0.000000000000007 | 75.5 | 30 | 51 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 87 | Q11150 | 251 | Y484_MYCTU Uncharacterized oxidoreductase Rv0... | 181 | 0.00000000000001 | 75.1 | 35 | 51 | GO:0005886; C:plasma membrane; IDA:MTBBASE. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 88 | P50199 | 256 | GNO_GLUOX Gluconate 5-dehydrogenase OS=Glucon... | 185 | 0.00000000000001 | 74.7 | 33 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008874; F:gluconate 5-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 89 | P39577 | 252 | DLTE_BACSU Uncharacterized oxidoreductase dlt... | 224 | 0.00000000000002 | 73.9 | 31 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 90 | P08074 | 244 | CBR2_MOUSE Carbonyl reductase [NADPH] 2 OS=Mu... | 171 | 0.00000000000003 | 73.6 | 32 | 51 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0043621; F:protein self-association; IDA:MGI. | | | | | | | | | | GO:0006116; P:NADH oxidation; TAS:MGI.::GO:0051262; P:protein tetramerization; IDA:MGI. | 91 | Q8FHD2 | 248 | YDFG_ECOL6 NADP-dependent L-serine/L-allo-thr... | 181 | 0.00000000000003 | 73.6 | 31 | 55 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | |