rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | O14756 | 317 | H17B6_HUMAN 17-beta-hydroxysteroid dehydrogen... | 194 | 4e-17 | 82.8 | 35 | 51 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IEA:EC.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC. | | | | | | | | | | GO:0006702; P:androgen biosynthetic process; NAS:UniProtKB.::GO:0006710; P:androgen catabolic process; TAS:UniProtKB. | 32 | Q4L8Y1 | 231 | Y0585_STAHJ Uncharacterized oxidoreductase SH... | 183 | 4e-17 | 81.6 | 32 | 56 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 33 | Q9BPW9 | 319 | DHRS9_HUMAN Dehydrogenase/reductase SDR famil... | 241 | 4e-17 | 82.8 | 32 | 47 | GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016854; F:racemase and epimerase activity; NAS:UniProtKB.::GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB.::GO:0047035; F:testosterone dehydrogenase (NAD+) activity; IDA:UniProtKB. | | | | | | | | | | GO:0042904; P:9-cis-retinoic acid biosynthetic process; IDA:UniProtKB.::GO:0008209; P:androgen metabolic process; IDA:UniProtKB.::GO:0030855; P:epithelial cell differentiation; NAS:UniProtKB.::GO:0042448; P:progesterone metabolic process; IDA:UniProtKB.::GO:0042572; P:retinol metabolic process; NAS:UniProtKB. | 34 | Q8U8I2 | 249 | SDH_AGRT5 Serine 3-dehydrogenase OS=Agrobacte... | 184 | 4e-17 | 82 | 30 | 51 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0031132; F:serine 3-dehydrogenase activity; IEA:EC. | | | | | | | | | | | 35 | P51661 | 386 | DHI2_MOUSE Corticosteroid 11-beta-dehydrogena... | 188 | 4e-17 | 83.6 | 34 | 51 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 36 | Q2FVD5 | 231 | Y2778_STAA8 Uncharacterized oxidoreductase SA... | 203 | 5e-17 | 81.3 | 29 | 50 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 37 | Q5HD73 | 231 | Y2488_STAAC Uncharacterized oxidoreductase SA... | 203 | 5e-17 | 81.3 | 29 | 50 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 38 | Q2FE21 | 231 | Y2422_STAA3 Uncharacterized oxidoreductase SA... | 203 | 5e-17 | 81.3 | 29 | 50 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 39 | Q0IH28 | 323 | DRS7B_XENLA Dehydrogenase/reductase SDR famil... | 238 | 6e-17 | 82.4 | 29 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 40 | Q9ZKW1 | 271 | VDLC_HELPJ Probable short-chain type dehydrog... | 264 | 8e-17 | 81.3 | 30 | 47 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 41 | Q59787 | 256 | DHSO_RHOSH Sorbitol dehydrogenase OS=Rhodobac... | 182 | 9e-17 | 80.9 | 35 | 54 | | | | | | | | | | | GO:0003939; F:L-iditol 2-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 42 | Q5HLD8 | 230 | Y2049_STAEQ Uncharacterized oxidoreductase SE... | 205 | 1e-16 | 80.1 | 27 | 54 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 43 | Q8CN40 | 230 | Y2036_STAES Uncharacterized oxidoreductase SE... | 205 | 1e-16 | 80.1 | 27 | 54 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 44 | Q937L4 | 250 | CPNA_COMTE Cyclopentanol dehydrogenase OS=Com... | 135 | 1e-16 | 80.5 | 36 | 56 | | | | | | | | | | | GO:0055041; F:cyclopentanol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 45 | Q8GAV9 | 250 | CPNA_COMS9 Cyclopentanol dehydrogenase OS=Com... | 135 | 1e-16 | 80.5 | 36 | 56 | | | | | | | | | | | GO:0055041; F:cyclopentanol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 46 | Q5R6U1 | 325 | DRS7B_PONAB Dehydrogenase/reductase SDR famil... | 208 | 2e-16 | 81.3 | 28 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 47 | Q8NUV9 | 231 | Y2403_STAAW Uncharacterized oxidoreductase MW... | 185 | 2e-16 | 79.7 | 30 | 53 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 48 | Q6G6J1 | 231 | Y2370_STAAS Uncharacterized oxidoreductase SA... | 185 | 2e-16 | 79.7 | 30 | 53 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 49 | Q920P0 | 244 | DCXR_RAT L-xylulose reductase OS=Rattus norve... | 240 | 2e-16 | 80.1 | 31 | 49 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050038; F:L-xylulose reductase (NADP+) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; IDA:UniProtKB.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0005997; P:xylulose metabolic process; IDA:UniProtKB. | 50 | Q920N9 | 244 | DCXR_CAVPO L-xylulose reductase OS=Cavia porc... | 240 | 2e-16 | 79.7 | 31 | 49 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050038; F:L-xylulose reductase (NADP+) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; IDA:UniProtKB.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0005997; P:xylulose metabolic process; IDA:UniProtKB. | 51 | P42317 | 257 | YXJF_BACSU Uncharacterized oxidoreductase yxj... | 200 | 2e-16 | 79.7 | 32 | 50 | | | | | | | | | | | GO:0003858; F:3-hydroxybutyrate dehydrogenase activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 52 | Q9KWN1 | 249 | SDH_RHIRD Serine 3-dehydrogenase OS=radiobact... | 184 | 2e-16 | 79.7 | 30 | 49 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0031132; F:serine 3-dehydrogenase activity; IEA:EC. | | | | | | | | | | | 53 | Q6IAN0 | 325 | DRS7B_HUMAN Dehydrogenase/reductase SDR famil... | 208 | 3e-16 | 80.5 | 28 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 54 | Q1WNP0 | 328 | DHB1_PANTR Estradiol 17-beta-dehydrogenase 1 ... | 188 | 3e-16 | 80.5 | 36 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006703; P:estrogen biosynthetic process; IEA:InterPro. | 55 | Q99RF5 | 231 | Y2478_STAAM Uncharacterized oxidoreductase SA... | 185 | 3e-16 | 79 | 30 | 53 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 56 | Q7A3L9 | 231 | Y2266_STAAN Uncharacterized oxidoreductase SA... | 185 | 3e-16 | 79 | 30 | 53 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 57 | P39483 | 261 | DHG2_BACME Glucose 1-dehydrogenase 2 OS=Bacil... | 200 | 4e-16 | 79.3 | 30 | 52 | | | | | | | | | | | GO:0047936; F:glucose 1-dehydrogenase [NAD(P) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.] | | | | | | | | | | | 58 | Q05016 | 267 | YM71_YEAST Uncharacterized oxidoreductase YMR... | 211 | 5e-16 | 79 | 31 | 50 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:SGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IDA:SGD. | | | | | | | | | | | 59 | P50233 | 400 | DHI2_RAT Corticosteroid 11-beta-dehydrogenase... | 202 | 5e-16 | 80.9 | 32 | 49 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:RGD.::GO:0051287; F:NAD binding; IDA:RGD.::GO:0005496; F:steroid binding; IPI:RGD. | | | | | | | | | | GO:0007565; P:female pregnancy; IEP:RGD.::GO:0008211; P:glucocorticoid metabolic process; IDA:RGD.::GO:0002017; P:regulation of blood volume by renal aldosterone; IMP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032094; P:response to food; IEP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IEP:RGD.] | 60 | Q5RJY4 | 325 | DRS7B_RAT Dehydrogenase/reductase SDR family ... | 206 | 7e-16 | 79.3 | 27 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 61 | P14061 | 328 | DHB1_HUMAN Estradiol 17-beta-dehydrogenase 1 ... | 188 | 7e-16 | 79.7 | 35 | 53 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; TAS:Reactome.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006703; P:estrogen biosynthetic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. |