| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
901 | Q5S007 | 2527 | LRRK2_HUMAN Leucine-rich repeat serine/threon... | 134 | 0.026 | 38.5 | 22 | 43 | GO:0032473; C:external side of mitochondrial outer membrane; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0043005; C:neuron projection; IDA:BHF-UCL.::GO:0043025; C:neuronal cell body; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0034211; F:GTP-dependent protein kinase activity; IMP:UniProtKB.::GO:0005096; F:GTPase activator activity; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:BHF-UCL.::GO:0004708; F:MAP kinase kinase activity; IDA:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0017048; F:Rho GTPase binding; IPI:BHF-UCL.::GO:0015631; F:tubulin binding; IDA:BHF-UCL. | | | | | | | | | | GO:0000186; P:activation of MAPKK activity; IDA:BHF-UCL.::GO:0008340; P:determination of adult lifespan; IMP:BHF-UCL.::GO:0035640; P:exploration behavior; IMP:BHF-UCL.::GO:0048312; P:intracellular distribution of mitochondria; IMP:BHF-UCL.::GO:2000173; P:negative regulation of branching morphogenesis of a nerve; IMP:BHF-UCL.::GO:0061002; P:negative regulation of dendritic spine morphogenesis; IMP:BHF-UCL.::GO:0007406; P:negative regulation of neuroblast proliferation; IMP:BHF-UCL.::GO:0014043; P:negative regulation of neuron maturation; IMP:BHF-UCL.::GO:0007528; P:neuromuscular junction development; IMP:BHF-UCL.::GO:0070997; P:neuron death; IMP:BHF-UCL.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.::GO:0010508; P:positive regulation of autophagy; ISS:BHF-UCL.::GO:0060161; P:positive regulation of dopamine receptor signaling pathway; IMP:BHF-UCL.::GO:0043068; P:positive regulation of programmed cell death; IDA:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:BHF-UCL.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0035564; P:regulation of kidney size; ISS:BHF-UCL.::GO:0040012; P:regulation of locomotion; IMP:BHF-UCL.::GO:0042391; P:regulation of membrane potential; IMP:BHF-UCL.::GO:0006979; P:response to oxidative stress; IMP:BHF-UCL.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0022028; P:tangential migration from the subventricular zone to the olfactory bulb; IMP:BHF-UCL. | 902 | Q9BU20 | 258 | RSG1_HUMAN REM2- and Rab-like small GTPase 1 ... | 129 | 0.029 | 38.1 | 26 | 41 | GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0005932; C:microtubule basal body; ISS:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0034613; P:cellular protein localization; ISS:UniProtKB.::GO:0042384; P:cilium assembly; ISS:UniProtKB.::GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0017157; P:regulation of exocytosis; ISS:UniProtKB.::GO:0031338; P:regulation of vesicle fusion; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 903 | A6Q226 | 843 | IF2_NITSB Translation initiation factor IF-2 ... | 183 | 0.032 | 38.1 | 23 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 904 | O95661 | 229 | DIRA3_HUMAN GTP-binding protein Di-Ras3 OS=Ho... | 196 | 0.033 | 37.7 | 22 | 42 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc. | | | | | | | | | | GO:0000079; P:regulation of cyclin-dependent protein kinase activity; TAS:ProtInc.::GO:0006349; P:regulation of gene expression by genetic imprinting; TAS:ProtInc.::GO:0007264; P:small GTPase mediated signal transduction; TAS:ProtInc. | 905 | Q5S006 | 2527 | LRRK2_MOUSE Leucine-rich repeat serine/threon... | 134 | 0.039 | 38.1 | 22 | 43 | GO:0045121; C:membrane raft; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0008021; C:synaptic vesicle; IDA:MGI.::GO:0005802; C:trans-Golgi network; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017048; F:Rho GTPase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0010508; P:positive regulation of autophagy; IMP:BHF-UCL.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:BHF-UCL.::GO:0035564; P:regulation of kidney size; IMP:BHF-UCL.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 906 | Q54Y14 | 194 | SAR1B_DICDI GTP-binding protein Sar1B OS=Dict... | 172 | 0.046 | 37 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 907 | Q6CY37 | 659 | GEM1_KLULA Mitochondrial Rho GTPase 1 OS=1267... | 180 | 0.051 | 37.7 | 23 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0019725; P:cellular homeostasis; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 908 | Q55E58 | 3184 | PATS1_DICDI Probable serine/threonine-protein... | 108 | 0.051 | 37.7 | 27 | 46 | GO:0042641; C:actomyosin; IPI:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:dictyBase. | | | | | | | | | | GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 909 | A2A825 | 258 | RSG1_MOUSE REM2- and Rab-like small GTPase 1 ... | 207 | 0.06 | 37 | 24 | 37 | GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0005932; C:microtubule basal body; ISS:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0034613; P:cellular protein localization; ISS:UniProtKB.::GO:0042384; P:cilium assembly; ISS:UniProtKB.::GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0017157; P:regulation of exocytosis; ISS:UniProtKB.::GO:0031338; P:regulation of vesicle fusion; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 910 | Q99PE9 | 201 | ARL4D_MOUSE ADP-ribosylation factor-like prot... | 195 | 0.098 | 36.2 | 29 | 41 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 911 | P34212 | 178 | ARL5_CAEEL ADP-ribosylation factor-like prote... | 139 | 0.13 | 35.8 | 24 | 40 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0051729; P:germline cell cycle switching, mitotic to meiotic cell cycle; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0000226; P:microtubule cytoskeleton organization; IMP:WormBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW. | 912 | Q9NYS0 | 192 | KBRS1_HUMAN NF-kappa-B inhibitor-interacting ... | 141 | 0.18 | 35.4 | 28 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; NAS:UniProtKB. | | | | | | | | | | GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; NAS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 913 | Q9CR56 | 191 | KBRS2_MOUSE NF-kappa-B inhibitor-interacting ... | 136 | 0.18 | 35.4 | 27 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 914 | Q9BH04 | 192 | KBRS1_MACFA NF-kappa-B inhibitor-interacting ... | 141 | 0.18 | 35.4 | 28 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 915 | A6QP66 | 204 | RERGL_BOVIN Ras-related and estrogen-regulate... | 170 | 0.19 | 35.4 | 24 | 41 | GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 916 | O59781 | 630 | GEM1_SCHPO Mitochondrial Rho GTPase 1 OS=Schi... | 186 | 1.4 | 33.1 | 23 | 42 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; ISS:PomBase.::GO:0005635; C:nuclear envelope; IDA:PomBase. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IC:PomBase.::GO:0003924; F:GTPase activity; ISS:PomBase. | | | | | | | | | | GO:0019725; P:cellular homeostasis; IEA:InterPro.::GO:0007005; P:mitochondrion organization; ISS:PomBase.::GO:0007264; P:small GTPase mediated signal transduction; IC:PomBase. | 917 | Q9NYR9 | 191 | KBRS2_HUMAN NF-kappa-B inhibitor-interacting ... | 136 | 0.24 | 35 | 27 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; NAS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 918 | Q7RZA2 | 629 | GEM1_NEUCR Mitochondrial Rho GTPase 1 OS=1257... | 139 | 0.27 | 35.4 | 24 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0019725; P:cellular homeostasis; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 919 | Q758X6 | 661 | GEM1_ASHGO Mitochondrial Rho GTPase 1 OS=Y-10... | 118 | 0.31 | 35.4 | 25 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0019725; P:cellular homeostasis; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 920 | Q58735 | 154 | Y1339_METJA Uncharacterized protein MJ1339 OS... | 91 | 0.34 | 34.3 | 26 | 47 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 921 | Q4I2W2 | 627 | GEM1_GIBZE Mitochondrial Rho GTPase 1 OS=(Whe... | 121 | 0.43 | 34.7 | 25 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0019725; P:cellular homeostasis; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 922 | Q32NS2 | 163 | KBRS2_XENLA NF-kappa-B inhibitor-interacting ... | 133 | 0.52 | 33.9 | 26 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 923 | Q5SSG5 | 203 | RSLAB_MOUSE Ras-like protein family member 10... | 187 | 0.62 | 33.9 | 20 | 40 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 924 | Q96S79 | 203 | RSLAB_HUMAN Ras-like protein family member 10... | 187 | 0.62 | 33.9 | 20 | 40 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 925 | P38763 | 256 | YHI2_YEAST Uncharacterized protein YHR022C OS... | 137 | 0.97 | 33.5 | 23 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 926 | Q54WS5 | 2147 | ROCO6_DICDI Probable serine/threonine-protein... | 67 | 1.6 | 33.1 | 25 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 927 | Q0I7K2 | 1129 | IF2_SYNS3 Translation initiation factor IF-2 ... | 127 | 1.8 | 33.1 | 24 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 928 | Q8CEC5 | 192 | KBRS1_MOUSE NF-kappa-B inhibitor-interacting ... | 133 | 2.1 | 32 | 26 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 929 | P55043 | 306 | RAD_RAT GTP-binding protein RAD OS=Rattus nor... | 168 | 2.1 | 32.3 | 22 | 40 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0030308; P:negative regulation of cell growth; IMP:RGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 930 | P48010 | 464 | SPN5_SCHPO Septin homolog spn5 OS=Schizosacch... | 61 | 2.9 | 32 | 31 | 52 | GO:0005634; C:nucleus; IDA:PomBase.::GO:0031105; C:septin complex; IEA:InterPro. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007126; P:meiosis; NAS:PomBase. | 931 | Q6DGQ1 | 192 | KBRS1_DANRE NF-kappa-B inhibitor-interacting ... | 133 | 3 | 31.6 | 27 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. |
