| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q9R0X5 | 1001 | RPGR_MOUSE X-linked retinitis pigmentosa GTPa... | 180 | 0.31 | 39.7 | 26 | 42 | GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005929; C:cilium; IDA:MGI.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005932; C:microtubule basal body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0042462; P:eye photoreceptor cell development; IMP:MGI.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; ISS:UniProtKB. | 32 | P28745 | 539 | RCC1_SCHPO Protein pim1 OS=Schizosaccharomyce... | 69 | 4.7 | 35.4 | 32 | 48 | GO:0000790; C:nuclear chromatin; NAS:PomBase. | | | | | | | | | | GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; IGI:PomBase. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; IMP:PomBase.::GO:0006406; P:mRNA export from nucleus; IMP:PomBase.::GO:0031291; P:Ran protein signal transduction; IGI:PomBase.::GO:0060623; P:regulation of chromosome condensation; IGI:PomBase.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IMP:PomBase.::GO:0006407; P:rRNA export from nucleus; ISS:PomBase.::GO:0090307; P:spindle assembly involved in mitosis; TAS:PomBase. | 33 | Q90XC2 | 697 | NEK8_DANRE Serine/threonine-protein kinase Ne... | 111 | 1.3 | 37.4 | 32 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 34 | Q91ZR4 | 698 | NEK8_MOUSE Serine/threonine-protein kinase Ne... | 151 | 3.1 | 36.2 | 30 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0072372; C:primary cilium; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 35 | Q96I51 | 464 | WBS16_HUMAN Williams-Beuren syndrome chromoso... | 223 | 0.0004 | 48.5 | 28 | 45 | | | | | | | | | | | | | | | | | | | | | | 36 | Q8IS20 | 1457 | GEFC_DICDI Ras guanine nucleotide exchange fa... | 86 | 0.1 | 41.2 | 30 | 50 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 37 | Q8TD19 | 979 | NEK9_HUMAN Serine/threonine-protein kinase Ne... | 250 | 0.013 | 43.9 | 22 | 41 | GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 38 | Q8K1R7 | 984 | NEK9_MOUSE Serine/threonine-protein kinase Ne... | 250 | 0.005 | 45.4 | 23 | 41 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 39 | Q52KW8 | 513 | RCC2_XENLA Protein RCC2 homolog OS=Xenopus la... | 103 | 0.56 | 38.5 | 26 | 50 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 40 | Q717B4 | 365 | TDPZ3_MOUSE TD and POZ domain-containing prot... | 184 | 0.003 | 45.4 | 23 | 41 | | | | | | | | | | | | | | | | | | | | | | 41 | Q7ZZC8 | 944 | NEK9_XENLA Serine/threonine-protein kinase Ne... | 219 | 0.035 | 42.7 | 26 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 42 | Q8BTU7 | 377 | RCCD1_MOUSE RCC1 domain-containing protein 1 ... | 240 | 0.004 | 45.4 | 25 | 40 | | | | | | | | | | | | | | | | | | | | | | 43 | A6NED2 | 376 | RCCD1_HUMAN RCC1 domain-containing protein 1 ... | 27 | 4.2 | 35.4 | 56 | 63 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | | | | | | | | | | | | 44 | Q96Q42 | 1657 | ALS2_HUMAN Alsin OS=Homo sapiens (Human). GN=... | 107 | 5.4 | 35.4 | 27 | 47 | GO:0005813; C:centrosome; IDA:MGI.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0030426; C:growth cone; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0043234; C:protein complex; IDA:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0043539; F:protein serine/threonine kinase activator activity; IDA:UniProtKB.::GO:0017137; F:Rab GTPase binding; IDA:UniProtKB.::GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IDA:UniProtKB.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IDA:UniProtKB.::GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; NAS:UniProtKB. | | | | | | | | | | GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0007032; P:endosome organization; NAS:UniProtKB.::GO:0032855; P:positive regulation of Rac GTPase activity; IDA:UniProtKB.::GO:0035022; P:positive regulation of Rac protein signal transduction; IC:UniProtKB.::GO:0051036; P:regulation of endosome size; IEP:UniProtKB. | 45 | P0C5Y8 | 1651 | ALS2_RAT Alsin OS=Rattus norvegicus (Rat). GN... | 74 | 0.12 | 40.8 | 31 | 58 | GO:0030424; C:axon; IDA:RGD.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0030426; C:growth cone; IDA:UniProtKB.::GO:0016020; C:membrane; IDA:UniProtKB.::GO:0005792; C:microsome; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0043234; C:protein complex; ISS:UniProtKB.::GO:0019717; C:synaptosome; IDA:RGD. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043539; F:protein serine/threonine kinase activator activity; ISS:UniProtKB.::GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; ISS:UniProtKB.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007409; P:axonogenesis; IMP:RGD.::GO:0008219; P:cell death; IMP:RGD.::GO:0001701; P:in utero embryonic development; IEP:RGD.::GO:0032855; P:positive regulation of Rac GTPase activity; ISS:UniProtKB.::GO:0016601; P:Rac protein signal transduction; IDA:RGD.::GO:0051036; P:regulation of endosome size; ISS:UniProtKB. | 46 | Q5BIW4 | 1657 | ALS2_PANTR Alsin OS=Pan troglodytes (Chimpanz... | 107 | 4.6 | 35.8 | 27 | 47 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0043234; C:protein complex; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB.::GO:0042598; C:vesicular fraction; ISS:UniProtKB. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043539; F:protein serine/threonine kinase activator activity; ISS:UniProtKB.::GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; ISS:UniProtKB.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0001662; P:behavioral fear response; ISS:UniProtKB.::GO:0016197; P:endosome transport; ISS:UniProtKB.::GO:0007626; P:locomotory behavior; ISS:UniProtKB.::GO:0007528; P:neuromuscular junction development; ISS:UniProtKB.::GO:0048812; P:neuron projection morphogenesis; ISS:UniProtKB.::GO:0032855; P:positive regulation of Rac GTPase activity; ISS:UniProtKB.::GO:0008104; P:protein localization; ISS:UniProtKB.::GO:0001881; P:receptor recycling; ISS:UniProtKB.::GO:0051036; P:regulation of endosome size; ISS:UniProtKB.::GO:0032313; P:regulation of Rab GTPase activity; ISS:UniProtKB.::GO:0006979; P:response to oxidative stress; ISS:UniProtKB.::GO:0035249; P:synaptic transmission, glutamatergic; ISS:UniProtKB.::GO:0016050; P:vesicle organization; ISS:UniProtKB. | 47 | Q5UPG5 | 421 | YL093_MIMIV Putative ankyrin repeat protein L... | 77 | 0.41 | 38.9 | 39 | 55 | | | | | | | | | | | | | | | | | | | | | | 48 | Q4R828 | 376 | RCCD1_MACFA RCC1 domain-containing protein 1 ... | 32 | 1.8 | 36.6 | 50 | 59 | | | | | | | | | | | | | | | | | | | | | | 49 | Q920R0 | 1651 | ALS2_MOUSE Alsin OS=Mus musculus (Mouse). GN=... | 107 | 4.2 | 35.8 | 26 | 49 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0030426; C:growth cone; ISS:UniProtKB.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0014069; C:postsynaptic density; IDA:MGI.::GO:0043234; C:protein complex; ISS:UniProtKB.::GO:0001726; C:ruffle; IDA:UniProtKB.::GO:0042598; C:vesicular fraction; ISS:UniProtKB. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043539; F:protein serine/threonine kinase activator activity; ISS:UniProtKB.::GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; ISS:UniProtKB.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0001662; P:behavioral fear response; IMP:MGI.::GO:0016197; P:endosome transport; IMP:MGI.::GO:0007626; P:locomotory behavior; IMP:MGI.::GO:0007528; P:neuromuscular junction development; IMP:MGI.::GO:0048812; P:neuron projection morphogenesis; ISS:UniProtKB.::GO:0032855; P:positive regulation of Rac GTPase activity; ISS:UniProtKB.::GO:0008104; P:protein localization; IMP:MGI.::GO:0001881; P:receptor recycling; IMP:MGI.::GO:0051036; P:regulation of endosome size; ISS:UniProtKB.::GO:0032313; P:regulation of Rab GTPase activity; IDA:MGI.::GO:0006979; P:response to oxidative stress; IMP:MGI.::GO:0035249; P:synaptic transmission, glutamatergic; IMP:MGI.::GO:0016050; P:vesicle organization; IDA:MGI. | 50 | Q9NB71 | 5233 | HIW_DROME E3 ubiquitin-protein ligase highwir... | 99 | 0.01 | 44.7 | 35 | 54 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IDA:FlyBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:FlyBase. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007628; P:adult walking behavior; NAS:FlyBase.::GO:0006914; P:autophagy; IDA:FlyBase.::GO:0030509; P:BMP signaling pathway; IPI:UniProtKB.::GO:0040011; P:locomotion; NAS:FlyBase.::GO:0030514; P:negative regulation of BMP signaling pathway; IGI:UniProtKB.::GO:0045886; P:negative regulation of synaptic growth at neuromuscular junction; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050808; P:synapse organization; IDA:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 51 | Q717B2 | 364 | TDPZ2_MOUSE TD and POZ domain-containing prot... | 153 | 0.01 | 43.9 | 23 | 42 | | | | | | | | | | | | | | | | | | | | | | 52 | Q54Q89 | 487 | RCCDC_DICDI RCC1 repeat-containing protein DD... | 125 | 0.014 | 43.5 | 26 | 52 | | | | | | | | | | | | | | | | | | | | | | 53 | Q6P8B3 | 374 | SPOP_XENTR Speckle-type POZ protein OS=Xenopu... | 152 | 0.017 | 43.1 | 22 | 44 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 54 | Q7ZX06 | 374 | SPOPA_XENLA Speckle-type POZ protein A OS=Xen... | 152 | 0.017 | 43.1 | 22 | 44 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 55 | Q2M2N2 | 392 | SPOPL_MOUSE Speckle-type POZ protein-like OS=... | 152 | 0.022 | 42.7 | 21 | 42 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 56 | Q6IQ16 | 392 | SPOPL_HUMAN Speckle-type POZ protein-like OS=... | 152 | 0.022 | 42.7 | 21 | 43 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 57 | A6QL63 | 1104 | BTBDB_HUMAN Ankyrin repeat and BTB/POZ domain... | 211 | 0.024 | 43.1 | 21 | 37 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro. | | | | | | | | | | | 58 | Q1LVW0 | 1021 | BTBBA_DANRE Ankyrin repeat and BTB/POZ domain... | 133 | 0.026 | 43.1 | 26 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0000786; C:nucleosome; IEA:InterPro.::GO:0005634; C:nucleus; IEA:InterPro. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro. | | | | | | | | | | GO:0006334; P:nucleosome assembly; IEA:InterPro. | 59 | Q5BL35 | 392 | SPOLA_DANRE Speckle-type POZ protein-like A O... | 152 | 0.027 | 42.4 | 24 | 45 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 60 | Q54HT1 | 1336 | TIRA_DICDI Protein tirA OS=Dictyostelium disc... | 130 | 0.031 | 42.7 | 26 | 48 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | | | | | | | | | | | GO:0008283; P:cell proliferation; IMP:dictyBase.::GO:0006952; P:defense response; IMP:dictyBase.::GO:0007165; P:signal transduction; IEA:InterPro. | 61 | Q8SSY6 | 1887 | SPKUL_DICDI Bifunctional serine/threonine-pro... | 117 | 4.7 | 35.8 | 30 | 44 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | |