rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
601 | D9IVE5 | 432 | ANM2_XENLA Protein arginine N-methyltransfera... | 84 | 3.9 | 34.3 | 23 | 48 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0030331; F:estrogen receptor binding; ISS:UniProtKB.::GO:0008469; F:histone-arginine N-methyltransferase activity; IDA:UniProtKB. | | | | | | | | | | GO:0048588; P:developmental cell growth; IMP:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; ISS:UniProtKB. | 602 | Q5T2T1 | 576 | MPP7_HUMAN MAGUK p55 subfamily member 7 OS=Ho... | 43 | 4 | 34.3 | 33 | 56 | GO:0097025; C:MPP7-DLG1-LIN7 complex; IDA:BHF-UCL.::GO:0005923; C:tight junction; IDA:BHF-UCL. | | | | | | | | | | GO:0032947; F:protein complex scaffold; IDA:BHF-UCL.::GO:0019904; F:protein domain specific binding; IPI:BHF-UCL.::GO:0046982; F:protein heterodimerization activity; IDA:BHF-UCL.::GO:0035591; F:signaling adaptor activity; NAS:BHF-UCL. | | | | | | | | | | GO:0030010; P:establishment of cell polarity; TAS:BHF-UCL.::GO:0031334; P:positive regulation of protein complex assembly; IDA:BHF-UCL.::GO:0071896; P:protein localization to adherens junction; IMP:BHF-UCL.::GO:0070830; P:tight junction assembly; IDA:BHF-UCL. | 603 | C5DQY5 | 371 | SHO1_ZYGRC High osmolarity signaling protein ... | 57 | 4.3 | 34.3 | 33 | 56 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 604 | Q6CHN0 | 1136 | SLA1_YARLI Actin cytoskeleton-regulatory comp... | 106 | 4.7 | 34.3 | 28 | 43 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 605 | A8N2Y6 | 1277 | MYO1_COPC7 Myosin-1 OS=9003) (Inky cap fungus... | 52 | 4.8 | 34.3 | 31 | 50 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 606 | Q8C0R0 | 979 | UBP37_MOUSE Ubiquitin carboxyl-terminal hydro... | 28 | 4.8 | 34.3 | 61 | 82 | | | | | | | | | | | GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0035871; P:protein K11-linked deubiquitination; ISS:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 607 | P31693 | 523 | SRC_RSVPA Tyrosine-protein kinase transformin... | 105 | 4.9 | 34.3 | 31 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 608 | Q8BVD5 | 576 | MPP7_MOUSE MAGUK p55 subfamily member 7 OS=Mu... | 57 | 5.1 | 33.9 | 28 | 51 | GO:0097025; C:MPP7-DLG1-LIN7 complex; ISS:BHF-UCL.::GO:0005923; C:tight junction; ISS:BHF-UCL. | | | | | | | | | | GO:0032947; F:protein complex scaffold; ISS:BHF-UCL.::GO:0019904; F:protein domain specific binding; ISS:BHF-UCL.::GO:0046982; F:protein heterodimerization activity; ISS:BHF-UCL. | | | | | | | | | | GO:0031334; P:positive regulation of protein complex assembly; ISS:BHF-UCL.::GO:0071896; P:protein localization to adherens junction; ISS:BHF-UCL.::GO:0070830; P:tight junction assembly; ISS:BHF-UCL. | 609 | Q5ZIR1 | 366 | SHLB1_CHICK Endophilin-B1 OS=Gallus gallus (C... | 100 | 5.2 | 33.9 | 29 | 42 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 610 | A7TI28 | 358 | SHO1_VANPO High osmolarity signaling protein ... | 57 | 5.2 | 33.9 | 35 | 60 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 611 | P42687 | 497 | SPK1_DUGTI Tyrosine-protein kinase SPK-1 OS=D... | 75 | 5.3 | 33.9 | 35 | 53 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 612 | Q9Y5X1 | 595 | SNX9_HUMAN Sorting nexin-9 OS=Homo sapiens (H... | 66 | 5.4 | 33.9 | 30 | 52 | GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IDA:UniProtKB.::GO:0031234; C:extrinsic to internal side of plasma membrane; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.::GO:0005802; C:trans-Golgi network; IDA:UniProtKB. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0006886; P:intracellular protein transport; IMP:UniProtKB.::GO:0060988; P:lipid tube assembly; IDA:UniProtKB.::GO:0043547; P:positive regulation of GTPase activity; IDA:UniProtKB.::GO:0032461; P:positive regulation of protein oligomerization; IDA:UniProtKB.::GO:0006898; P:receptor-mediated endocytosis; IMP:UniProtKB. | 613 | E3RIP0 | 309 | SHO1_PYRTT High osmolarity signaling protein ... | 57 | 5.4 | 33.5 | 35 | 54 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 614 | Q7TNF8 | 1846 | RIMB1_MOUSE Peripheral-type benzodiazepine re... | 65 | 5.4 | 34.3 | 32 | 51 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 615 | B2VV00 | 295 | SHO1_PYRTR High osmolarity signaling protein ... | 57 | 5.6 | 33.5 | 35 | 54 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 616 | Q6AYE2 | 365 | SHLB1_RAT Endophilin-B1 OS=Rattus norvegicus ... | 61 | 6 | 33.5 | 30 | 46 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 617 | A7EK16 | 1230 | MYO1_SCLS1 Myosin-1 OS=mold) (Whetzelinia scl... | 52 | 7.8 | 33.5 | 29 | 46 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 618 | Q5RDQ2 | 675 | MPP5_PONAB MAGUK p55 subfamily member 5 OS=Po... | 51 | 7.9 | 33.5 | 33 | 55 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 619 | C5DE38 | 342 | SHO1_LACTC High osmolarity signaling protein ... | 57 | 8 | 33.1 | 35 | 60 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 620 | Q8N3R9 | 675 | MPP5_HUMAN MAGUK p55 subfamily member 5 OS=Ho... | 51 | 8 | 33.5 | 33 | 55 | GO:0005737; C:cytoplasm; IDA:LIFEdb.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0019904; F:protein domain specific binding; IPI:BHF-UCL. | | | | | | | | | | GO:0070830; P:tight junction assembly; TAS:Reactome. | 621 | Q8N4X5 | 818 | AF1L2_HUMAN Actin filament-associated protein... | 69 | 8.5 | 33.5 | 32 | 45 | GO:0016235; C:aggresome; IDA:HPA.::GO:0005737; C:cytoplasm; IDA:HGNC.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030296; F:protein tyrosine kinase activator activity; IDA:HGNC.::GO:0042169; F:SH2 domain binding; IPI:HGNC.::GO:0017124; F:SH3 domain binding; IPI:HGNC. | | | | | | | | | | GO:0006954; P:inflammatory response; IDA:HGNC.::GO:0045742; P:positive regulation of epidermal growth factor receptor signaling pathway; IDA:HGNC.::GO:0032757; P:positive regulation of interleukin-8 production; IDA:HGNC.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:HGNC.::GO:0032675; P:regulation of interleukin-6 production; IDA:HGNC.::GO:0007346; P:regulation of mitotic cell cycle; IDA:HGNC. | 622 | Q9JLB2 | 675 | MPP5_MOUSE MAGUK p55 subfamily member 5 OS=Mu... | 51 | 8.5 | 33.5 | 33 | 55 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0043219; C:lateral loop; IDA:BHF-UCL.::GO:0035749; C:myelin sheath adaxonal region; IDA:BHF-UCL.::GO:0043220; C:Schmidt-Lanterman incisure; IDA:BHF-UCL.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0032287; P:peripheral nervous system myelin maintenance; IMP:BHF-UCL.::GO:0035750; P:protein localization to myelin sheath abaxonal region; IMP:BHF-UCL. | 623 | Q07014 | 512 | LYN_RAT Tyrosine-protein kinase Lyn OS=Rattus... | 55 | 8.9 | 33.1 | 42 | 56 | GO:0034666; C:alpha2-beta1 integrin complex; IDA:RGD.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0030061; C:mitochondrial crista; IDA:RGD.::GO:0005758; C:mitochondrial intermembrane space; IDA:RGD.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043208; F:glycosphingolipid binding; IPI:RGD.::GO:0005178; F:integrin binding; IDA:RGD.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0051219; F:phosphoprotein binding; IPI:RGD.::GO:0005161; F:platelet-derived growth factor receptor binding; IPI:RGD.::GO:0031625; F:ubiquitin protein ligase binding; IPI:RGD. | | | | | | | | | | GO:0001782; P:B cell homeostasis; ISS:UniProtKB.::GO:0034605; P:cellular response to heat; IEP:RGD.::GO:0050663; P:cytokine secretion; IMP:RGD.::GO:0097028; P:dendritic cell differentiation; ISS:UniProtKB.::GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0002774; P:Fc receptor mediated inhibitory signaling pathway; ISS:UniProtKB.::GO:0002431; P:Fc receptor mediated stimulatory signaling pathway; ISS:UniProtKB.::GO:0002553; P:histamine secretion by mast cell; IMP:RGD.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0031663; P:lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0043407; P:negative regulation of MAP kinase activity; ISS:UniProtKB.::GO:0070667; P:negative regulation of mast cell proliferation; ISS:UniProtKB.::GO:0001933; P:negative regulation of protein phosphorylation; ISS:UniProtKB.::GO:0034136; P:negative regulation of toll-like receptor 2 signaling pathway; ISS:UniProtKB.::GO:0034144; P:negative regulation of toll-like receptor 4 signaling pathway; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; IEP:RGD.::GO:0002576; P:platelet degranulation; ISS:UniProtKB.::GO:2000670; P:positive regulation of dendritic cell apoptotic process; ISS:UniProtKB.::GO:0060369; P:positive regulation of Fc receptor mediated stimulatory signaling pathway; IMP:RGD.::GO:0060252; P:positive regulation of glial cell proliferation; IDA:RGD.::GO:0070447; P:positive regulation of oligodendrocyte progenitor proliferation; IMP:RGD.::GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; ISS:UniProtKB.::GO:0050855; P:regulation of B cell receptor signaling pathway; ISS:UniProtKB.::GO:0045646; P:regulation of erythrocyte differentiation; ISS:UniProtKB.::GO:0043304; P:regulation of mast cell degranulation; ISS:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.::GO:0051279; P:regulation of release of sequestered calcium ion into cytosol; IMP:RGD.::GO:0043200; P:response to amino acid stimulus; IEP:RGD.::GO:0048678; P:response to axon injury; IEP:RGD.::GO:0009743; P:response to carbohydrate stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0006991; P:response to sterol depletion; IEP:RGD.::GO:0009636; P:response to toxin; IEP:RGD.::GO:0002513; P:tolerance induction to self antigen; ISS:UniProtKB. | 624 | A1IGU3 | 676 | ARH37_RAT Rho guanine nucleotide exchange fac... | 69 | 9.1 | 33.5 | 32 | 49 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 625 | O08838 | 683 | AMPH_RAT Amphiphysin OS=Rattus norvegicus (Ra... | 125 | 9.1 | 33.5 | 30 | 41 | GO:0043679; C:axon terminus; IDA:RGD.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0046982; F:protein heterodimerization activity; IPI:RGD. | | | | | | | | | | GO:0045807; P:positive regulation of endocytosis; IMP:RGD.::GO:0043547; P:positive regulation of GTPase activity; IDA:RGD. | 626 | Q6DCZ7 | 543 | FBP1L_XENLA Formin-binding protein 1-like OS=... | 56 | 9.6 | 33.1 | 30 | 55 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. |