rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
331 | Q10410 | 510 | YD85_SCHPO Probable ADP-ribosylation factor-b... | 125 | 0.001 | 45.8 | 26 | 48 | GO:0030131; C:clathrin adaptor complex; IEA:InterPro.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0044431; C:Golgi apparatus part; IEA:InterPro.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005802; C:trans-Golgi network; ISS:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0006896; P:Golgi to vacuole transport; ISS:PomBase.::GO:0006886; P:intracellular protein transport; IC:PomBase. | 332 | P09769 | 529 | FGR_HUMAN Tyrosine-protein kinase Fgr OS=Homo... | 64 | 0.001 | 45.8 | 38 | 50 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0034988; F:Fc-gamma receptor I complex binding; IDA:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0001784; F:phosphotyrosine binding; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0050830; P:defense response to Gram-positive bacterium; ISS:UniProtKB.::GO:0002768; P:immune response-regulating cell surface receptor signaling pathway; TAS:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007229; P:integrin-mediated signaling pathway; IMP:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:0050715; P:positive regulation of cytokine secretion; ISS:UniProtKB.::GO:0043306; P:positive regulation of mast cell degranulation; ISS:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0045088; P:regulation of innate immune response; ISS:UniProtKB.::GO:0050764; P:regulation of phagocytosis; ISS:UniProtKB.::GO:0045859; P:regulation of protein kinase activity; ISS:UniProtKB.::GO:0009615; P:response to virus; TAS:ProtInc. | 333 | Q9DC07 | 270 | LNEBL_MOUSE LIM zinc-binding domain-containin... | 58 | 0.001 | 45.1 | 33 | 60 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 334 | P98171 | 946 | RHG04_HUMAN Rho GTPase-activating protein 4 O... | 37 | 0.001 | 45.8 | 43 | 59 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; TAS:ProtInc.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; TAS:ProtInc.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007266; P:Rho protein signal transduction; TAS:ProtInc. | 335 | A6H8I2 | 753 | SGSM3_XENLA Small G protein signaling modulat... | 54 | 0.001 | 45.8 | 39 | 56 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005097; F:Rab GTPase activator activity; IEA:InterPro. | | | | | | | | | | | 336 | Q92266 | 380 | PEX13_PICPA Peroxisomal membrane protein PEX1... | 60 | 0.001 | 45.4 | 40 | 57 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0016560; P:protein import into peroxisome matrix, docking; IEA:InterPro. | 337 | A5GFW5 | 784 | CASS4_PIG Cas scaffolding protein family memb... | 57 | 0.002 | 45.4 | 37 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 338 | P35991 | 659 | BTK_MOUSE Tyrosine-protein kinase BTK OS=Mus ... | 73 | 0.002 | 45.4 | 33 | 53 | GO:0031410; C:cytoplasmic vesicle; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0048469; P:cell maturation; IMP:MGI.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; IMP:MGI.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 339 | Q3UND0 | 358 | SKAP2_MOUSE Src kinase-associated phosphoprot... | 56 | 0.002 | 44.7 | 38 | 55 | GO:0005737; C:cytoplasm; IDA:MGI. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042113; P:B cell activation; IEA:UniProtKB-KW.::GO:0008285; P:negative regulation of cell proliferation; IMP:MGI. | 340 | Q5U597 | 330 | SKA2B_XENLA Src kinase-associated phosphoprot... | 74 | 0.002 | 44.7 | 31 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042113; P:B cell activation; IEA:UniProtKB-KW. | 341 | O74352 | 466 | HOB1_SCHPO Protein hob1 OS=Schizosaccharomyce... | 53 | 0.002 | 44.7 | 43 | 53 | GO:0051285; C:cell cortex of cell tip; TAS:PomBase.::GO:0031097; C:medial cortex; TAS:PomBase. | | | | | | | | | | GO:0051020; F:GTPase binding; NAS:PomBase. | | | | | | | | | | GO:0030702; P:chromatin silencing at centromere; IMP:PomBase.::GO:0006348; P:chromatin silencing at telomere; IMP:PomBase.::GO:0007163; P:establishment or maintenance of cell polarity; IGI:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0006974; P:response to DNA damage stimulus; IGI:PomBase.::GO:0000723; P:telomere maintenance; IMP:PomBase. | 342 | Q9P2A4 | 366 | ABI3_HUMAN ABI gene family member 3 OS=Homo s... | 57 | 0.002 | 44.7 | 39 | 49 | GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0030027; C:lamellipodium; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006928; P:cellular component movement; NAS:UniProtKB.::GO:0030334; P:regulation of cell migration; IDA:MGI. | 343 | P00526 | 526 | SRC_RSVP Tyrosine-protein kinase transforming... | 103 | 0.002 | 44.7 | 31 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 344 | Q8BYZ1 | 367 | ABI3_MOUSE ABI gene family member 3 OS=Mus mu... | 57 | 0.002 | 44.7 | 39 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 345 | Q4P3H6 | 1207 | SLA1_USTMA Actin cytoskeleton-regulatory comp... | 50 | 0.07 | 40.4 | 36 | 56 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 346 | Q06187 | 659 | BTK_HUMAN Tyrosine-protein kinase BTK OS=Homo... | 64 | 0.002 | 45.1 | 36 | 55 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0045121; C:membrane raft; IDA:HGNC.::GO:0005634; C:nucleus; TAS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; TAS:HGNC.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB. | | | | | | | | | | GO:0002250; P:adaptive immune response; TAS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042113; P:B cell activation; TAS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; TAS:UniProtKB.::GO:0019722; P:calcium-mediated signaling; TAS:HGNC.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:UniProtKB.::GO:0007498; P:mesoderm development; TAS:ProtInc.::GO:0045579; P:positive regulation of B cell differentiation; TAS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:UniProtKB.::GO:0002902; P:regulation of B cell apoptotic process; TAS:UniProtKB.::GO:0002721; P:regulation of B cell cytokine production; TAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 347 | O14302 | 886 | CYK3_SCHPO cytokinesis protein 3 OS=Schizosac... | 59 | 0.002 | 45.1 | 42 | 56 | GO:0005826; C:actomyosin contractile ring; NAS:PomBase.::GO:0051286; C:cell tip; IDA:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0033205; P:cell cycle cytokinesis; NAS:PomBase. | 348 | O14259 | 415 | YFP2_SCHPO SH3 domain-containing protein C7D4... | 57 | 0.002 | 44.7 | 35 | 54 | GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0005515; F:protein binding; IPI:PomBase. | | | | | | | | | | GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:2000157; P:negative regulation of ubiquitin-specific protease activity; IMP:PomBase. | 349 | O43281 | 561 | EFS_HUMAN Embryonal Fyn-associated substrate ... | 70 | 0.002 | 44.7 | 39 | 49 | GO:0005737; C:cytoplasm; TAS:ProtInc. | | | | | | | | | | GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; TAS:ProtInc. | 350 | P25020 | 526 | SRC_RSVH1 Tyrosine-protein kinase transformin... | 103 | 0.003 | 44.7 | 31 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 351 | Q8TC17 | 118 | GRAPL_HUMAN GRB2-related adapter protein-like... | 49 | 0.003 | 42 | 39 | 57 | | | | | | | | | | | | | | | | | | | | | | 352 | P27446 | 537 | FYN_XIPHE Tyrosine-protein kinase Fyn OS=Xiph... | 83 | 0.003 | 44.7 | 33 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 353 | Q9CX99 | 217 | GRAP_MOUSE GRB2-related adapter protein OS=Mu... | 49 | 0.029 | 40.4 | 39 | 57 | | | | | | | | | | | | | | | | | | | | | | 354 | Q812A2 | 1099 | SRGP3_MOUSE SLIT-ROBO Rho GTPase-activating p... | 81 | 0.003 | 44.7 | 32 | 49 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 355 | O76041 | 1014 | NEBL_HUMAN Nebulette OS=Homo sapiens (Human).... | 52 | 0.003 | 44.7 | 35 | 63 | GO:0001725; C:stress fiber; IDA:UniProtKB.::GO:0030018; C:Z disc; IDA:UniProtKB. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:UniProtKB.::GO:0031005; F:filamin binding; IPI:UniProtKB.::GO:0008307; F:structural constituent of muscle; NAS:UniProtKB.::GO:0005523; F:tropomyosin binding; IPI:UniProtKB. | | | | | | | | | | GO:0071691; P:cardiac muscle thin filament assembly; IMP:UniProtKB. | 356 | Q5XGP7 | 330 | SKA2A_XENLA Src kinase-associated phosphoprot... | 77 | 0.003 | 43.9 | 32 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042113; P:B cell activation; IEA:UniProtKB-KW. | 357 | Q9BVN2 | 902 | RUSC1_HUMAN RUN and SH3 domain-containing pro... | 50 | 0.003 | 44.7 | 36 | 58 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | | 358 | Q80U22 | 1514 | RUSC2_MOUSE Iporin OS=Mus musculus (Mouse). G... | 50 | 0.003 | 44.7 | 42 | 56 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 359 | Q9DDA9 | 477 | PACN2_XENLA Protein kinase C and casein kinas... | 56 | 0.003 | 44.3 | 43 | 63 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 360 | Q64355 | 560 | EFS_MOUSE Embryonal Fyn-associated substrate ... | 70 | 0.003 | 44.3 | 39 | 49 | | | | | | | | | | | GO:0017124; F:SH3 domain binding; IDA:MGI. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 361 | Q7Z6B7 | 1085 | SRGP1_HUMAN SLIT-ROBO Rho GTPase-activating p... | 69 | 0.003 | 44.7 | 35 | 49 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome. |