rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q9Y8A5 | 3038 | LNKS_ASPTE Lovastatin nonaketide synthase OS=... | 965 | 2e-73 | 277 | 28 | 43 | | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; NAS:UniProtKB.::GO:0050637; F:lovastatin nonaketide synthase activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0031177; F:phosphopantetheine binding; NAS:UniProtKB.::GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; NAS:UniProtKB. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0030639; P:polyketide biosynthetic process; IMP:UniProtKB. | 32 | Q54FI3 | 2968 | PKS37_DICDI Probable polyketide synthase 37 O... | 1128 | 4e-73 | 276 | 23 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IC:dictyBase. | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016210; F:naringenin-chalcone synthase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0031148; P:DIF-1 biosynthetic process; IMP:dictyBase.::GO:0030639; P:polyketide biosynthetic process; IDA:dictyBase.::GO:0031288; P:sorocarp morphogenesis; IMP:dictyBase.::GO:0031149; P:sorocarp stalk cell differentiation; IMP:dictyBase. | 33 | Q54B49 | 3092 | PKS45_DICDI Probable polyketide synthase 45 O... | 1005 | 2e-72 | 274 | 25 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 34 | P96204 | 1488 | PPSE_MYCTU Phthiocerol synthesis polyketide s... | 975 | 1e-71 | 270 | 28 | 42 | GO:0005618; C:cell wall; IDA:MTBBASE.::GO:0005886; C:plasma membrane; IDA:MTBBASE. | | | | | | | | | | GO:0004315; F:3-oxoacyl-[acyl-carrier-protein synthase activity; IDA:MTBBASE.::GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0071770; P:DIM/DIP cell wall layer assembly; IDA:MTBBASE.::GO:0006633; P:fatty acid biosynthetic process; IDA:MTBBASE.] | 35 | Q7TXL6 | 1488 | PPSE_MYCBO Phthiocerol/phenolphthiocerol synt... | 975 | 1e-71 | 270 | 28 | 42 | | | | | | | | | | | GO:0004315; F:3-oxoacyl-[acyl-carrier-protein synthase activity; IEA:EC.::GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0071766; P:Actinobacterium-type cell wall biogenesis; IMP:UniProtKB.::GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.::GO:0008610; P:lipid biosynthetic process; IMP:UniProtKB.] | 36 | Q54QD3 | 2499 | PKS22_DICDI Probable polyketide synthase 22 O... | 974 | 3e-71 | 270 | 24 | 43 | | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 37 | Q86JI5 | 2512 | PKS5_DICDI Probable polyketide synthase 5 OS=... | 878 | 6e-71 | 269 | 24 | 45 | | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 38 | Q54ED6 | 2542 | PKS41_DICDI Probable polyketide synthase 41 O... | 952 | 1e-70 | 268 | 25 | 43 | GO:0005615; C:extracellular space; IDA:dictyBase. | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 39 | B0G0Z9 | 2924 | PKS6_DICDI Probable polyketide synthase 6 OS=... | 917 | 2e-70 | 268 | 25 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 40 | B0G100 | 2513 | PKS7_DICDI Probable polyketide synthase 7 OS=... | 918 | 3e-70 | 267 | 24 | 44 | | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 41 | Q54QD1 | 2499 | PKS23_DICDI Probable polyketide synthase 23 O... | 965 | 5e-70 | 266 | 24 | 43 | | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 42 | Q558Y6 | 2998 | PKS14_DICDI Probable polyketide synthase 14 O... | 995 | 6e-70 | 266 | 26 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 43 | Q55DM7 | 3010 | PKS2_DICDI Probable polyketide synthase 2 OS=... | 974 | 1e-69 | 265 | 25 | 43 | | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 44 | Q86AE3 | 2931 | PKS9_DICDI Probable polyketide synthase 9/36 ... | 871 | 4e-69 | 263 | 25 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 45 | Q55CN6 | 2837 | PKS3_DICDI Probable polyketide synthase 3 OS=... | 938 | 7e-69 | 262 | 24 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 46 | Q54B51 | 3078 | PKS44_DICDI Probable polyketide synthase 44 O... | 980 | 3e-68 | 261 | 26 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 47 | P40872 | 4262 | PKSM_BACSU Polyketide synthase PksM OS=Bacill... | 563 | 1e-51 | 206 | 29 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.::GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro. | | | | | | | | | | GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW. | 48 | Q05470 | 4538 | PKSL_BACSU Polyketide synthase PksL OS=Bacill... | 435 | 3e-41 | 172 | 31 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.::GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW. | | | | | | | | | | GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW. | 49 | Q54ED7 | 2552 | PKS40_DICDI Probable polyketide synthase 40 O... | 953 | 1e-67 | 258 | 24 | 43 | GO:0005615; C:extracellular space; IDA:dictyBase. | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 50 | B0G101 | 2514 | PKS8_DICDI Probable polyketide synthase 8/35 ... | 877 | 1e-65 | 252 | 24 | 45 | | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 51 | B0G103 | 2485 | PKS10_DICDI Probable polyketide synthase 10 O... | 964 | 5e-65 | 249 | 25 | 45 | | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 52 | P40806 | 5043 | PKSJ_BACSU Polyketide synthase PksJ OS=Bacill... | 529 | 2e-41 | 173 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.::GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW. | | | | | | | | | | GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW. | 53 | P49327 | 2511 | FAS_HUMAN Fatty acid synthase OS=Homo sapiens... | 238 | 0.009 | 45.1 | 26 | 42 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0004317; F:3-hydroxypalmitoyl-[acyl-carrier-protein dehydratase activity; IEA:EC.::GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0004315; F:3-oxoacyl-[acyl-carrier-protein synthase activity; IEA:EC.::GO:0004313; F:[acyl-carrier-protein S-acetyltransferase activity; IEA:EC.::GO:0004314; F:[acyl-carrier-protein S-malonyltransferase activity; IEA:EC.::GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0004319; F:enoyl-[acyl-carrier-protein reductase (NADPH, B-specific) activity; IEA:EC.::GO:0016295; F:myristoyl-[acyl-carrier-protein hydrolase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004320; F:oleoyl-[acyl-carrier-protein hydrolase activity; IEA:EC.::GO:0016296; F:palmitoyl-[acyl-carrier-protein hydrolase activity; IEA:EC.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.]::GO:0005515; F:protein binding; IPI:UniProtKB.]::GO:0008270; F:zinc ion binding; IEA:InterPro.] | | | | | | | | | | GO:0006112; P:energy reserve metabolic process; TAS:Reactome.]::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]::GO:0035338; P:long-chain fatty-acyl-CoA biosynthetic process; TAS:Reactome.]::GO:0015939; P:pantothenate metabolic process; TAS:Reactome.]::GO:0031325; P:positive regulation of cellular metabolic process; TAS:Reactome.]::GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.] | 54 | P19096 | 2504 | FAS_MOUSE Fatty acid synthase OS=Mus musculus... | 218 | 0.27 | 40.4 | 27 | 43 | GO:0042587; C:glycogen granule; IDA:MGI.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0004317; F:3-hydroxypalmitoyl-[acyl-carrier-protein dehydratase activity; IEA:EC.::GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0004315; F:3-oxoacyl-[acyl-carrier-protein synthase activity; IEA:EC.::GO:0004313; F:[acyl-carrier-protein S-acetyltransferase activity; IEA:EC.::GO:0004314; F:[acyl-carrier-protein S-malonyltransferase activity; IEA:EC.::GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0004319; F:enoyl-[acyl-carrier-protein reductase (NADPH, B-specific) activity; IEA:EC.::GO:0016295; F:myristoyl-[acyl-carrier-protein hydrolase activity; IEA:EC.]::GO:0000166; F:nucleotide binding; IEA:InterPro.]::GO:0004320; F:oleoyl-[acyl-carrier-protein] hydrolase activity; IEA:EC.]::GO:0016296; F:palmitoyl-[acyl-carrier-protein] hydrolase activity; IEA:EC.]::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.]::GO:0008270; F:zinc ion binding; IEA:InterPro.] | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.] | 55 | Q54TW0 | 2999 | PKS18_DICDI Probable polyketide synthase 18 O... | 977 | 1e-63 | 245 | 25 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 56 | B0G170 | 2690 | PKS28_DICDI Probable polyketide synthase 28 O... | 851 | 2e-63 | 244 | 24 | 45 | | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 57 | P12276 | 2512 | FAS_CHICK Fatty acid synthase OS=Gallus gallu... | 916 | 3e-63 | 244 | 26 | 42 | | | | | | | | | | | GO:0004317; F:3-hydroxypalmitoyl-[acyl-carrier-protein dehydratase activity; IEA:EC.::GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0004315; F:3-oxoacyl-[acyl-carrier-protein synthase activity; IEA:EC.::GO:0004313; F:[acyl-carrier-protein S-acetyltransferase activity; IEA:EC.::GO:0004314; F:[acyl-carrier-protein S-malonyltransferase activity; IEA:EC.::GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0004319; F:enoyl-[acyl-carrier-protein reductase (NADPH, B-specific) activity; IEA:EC.::GO:0016295; F:myristoyl-[acyl-carrier-protein hydrolase activity; IEA:EC.]::GO:0000166; F:nucleotide binding; IEA:InterPro.]::GO:0004320; F:oleoyl-[acyl-carrier-protein] hydrolase activity; IEA:EC.]::GO:0016296; F:palmitoyl-[acyl-carrier-protein] hydrolase activity; IEA:EC.]::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.]::GO:0008270; F:zinc ion binding; IEA:InterPro.] | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.] | 58 | Q559A9 | 2551 | PKS13_DICDI Probable polyketide synthase 13 O... | 965 | 4e-63 | 244 | 23 | 42 | | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 59 | P96284 | 496 | PKS15_MYCTU Putative inactive phenolphthiocer... | 437 | 4e-63 | 231 | 34 | 50 | GO:0005829; C:cytosol; IDA:MTBBASE. | | | | | | | | | | GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:InterPro. | | | | | | | | | | GO:0009247; P:glycolipid biosynthetic process; IMP:MTBBASE. | 60 | Q54T36 | 2778 | PKS19_DICDI Probable polyketide synthase 19 O... | 988 | 6e-62 | 240 | 24 | 43 | | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. | 61 | O31782 | 5488 | PKSN_BACSU Polyketide synthase PksN OS=Bacill... | 541 | 6e-42 | 174 | 27 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.::GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro. |