rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q5R9W5 | 414 | WWOX_PONAB WW domain-containing oxidoreductas... | 263 | 3e-29 | 119 | 29 | 45 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 2 | Q91WL8 | 414 | WWOX_MOUSE WW domain-containing oxidoreductas... | 260 | 7e-29 | 118 | 30 | 47 | GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.::GO:0006917; P:induction of apoptosis; IDA:MGI.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0001649; P:osteoblast differentiation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0048705; P:skeletal system morphogenesis; IMP:MGI.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 3 | Q9NZC7 | 414 | WWOX_HUMAN WW domain-containing oxidoreductas... | 263 | 1e-28 | 117 | 29 | 45 | GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005739; C:mitochondrion; ISS:BHF-UCL.::GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0050662; F:coenzyme binding; TAS:UniProtKB.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; NAS:UniProtKB.::GO:0046983; F:protein dimerization activity; TAS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.::GO:0006917; P:induction of apoptosis; ISS:BHF-UCL.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0048705; P:skeletal system morphogenesis; ISS:BHF-UCL.::GO:0008202; P:steroid metabolic process; TAS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 4 | Q5F389 | 414 | WWOX_CHICK WW domain-containing oxidoreductas... | 260 | 5e-28 | 115 | 29 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 5 | A2RVM0 | 322 | TIC32_ARATH Short-chain dehydrogenase TIC 32,... | 261 | 1e-27 | 114 | 30 | 47 | GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 6 | Q8BYK4 | 316 | RDH12_MOUSE Retinol dehydrogenase 12 OS=Mus m... | 294 | 5e-26 | 109 | 30 | 44 | GO:0005622; C:intracellular; ISS:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0042572; P:retinol metabolic process; ISS:UniProtKB.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 7 | Q8TC12 | 318 | RDH11_HUMAN Retinol dehydrogenase 11 OS=Homo ... | 302 | 3e-24 | 103 | 28 | 44 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0052650; F:NADP-retinol dehydrogenase activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0042574; P:retinal metabolic process; IDA:MGI.::GO:0042572; P:retinol metabolic process; ISS:UniProtKB.::GO:0008202; P:steroid metabolic process; TAS:Reactome. | 8 | Q8CEE7 | 334 | RDH13_MOUSE Retinol dehydrogenase 13 OS=Mus m... | 298 | 3e-24 | 104 | 28 | 45 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 9 | Q8NBN7 | 331 | RDH13_HUMAN Retinol dehydrogenase 13 OS=Homo ... | 299 | 1e-23 | 102 | 28 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 10 | Q9VLU5 | 409 | WWOX_DROME WW domain-containing oxidoreductas... | 261 | 2e-23 | 102 | 28 | 43 | GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:FlyBase.::GO:0010212; P:response to ionizing radiation; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 11 | Q6RVV4 | 316 | TIC32_PEA Short-chain dehydrogenase TIC 32, c... | 292 | 7e-23 | 100 | 27 | 43 | GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 12 | Q803A8 | 412 | WWOX_DANRE WW domain-containing oxidoreductas... | 268 | 7e-23 | 100 | 29 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 13 | Q96NR8 | 316 | RDH12_HUMAN Retinol dehydrogenase 12 OS=Homo ... | 293 | 2e-22 | 98.2 | 28 | 43 | GO:0005622; C:intracellular; IDA:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0045494; P:photoreceptor cell maintenance; TAS:UniProtKB.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0042572; P:retinol metabolic process; IDA:UniProtKB. | 14 | P59837 | 316 | RDH12_BOVIN Retinol dehydrogenase 12 OS=Bos t... | 298 | 7e-22 | 97.1 | 28 | 43 | GO:0005622; C:intracellular; ISS:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0042572; P:retinol metabolic process; ISS:UniProtKB.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 15 | Q9QYF1 | 316 | RDH11_MOUSE Retinol dehydrogenase 11 OS=Mus m... | 295 | 1e-21 | 96.3 | 28 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0001917; C:photoreceptor inner segment; IDA:MGI. | | | | | | | | | | GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0016062; P:adaptation of rhodopsin mediated signaling; IMP:MGI.::GO:0042572; P:retinol metabolic process; ISS:UniProtKB. | 16 | Q9HBH5 | 336 | RDH14_HUMAN Retinol dehydrogenase 14 OS=Homo ... | 307 | 3e-21 | 95.5 | 31 | 41 | GO:0005783; C:endoplasmic reticulum; IDA:LIFEdb. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 17 | Q03326 | 298 | OXIR_STRAT Probable oxidoreductase OS=Strepto... | 286 | 1e-20 | 93.2 | 30 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 18 | Q9ERI6 | 334 | RDH14_MOUSE Retinol dehydrogenase 14 OS=Mus m... | 304 | 2e-20 | 92.8 | 30 | 41 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 19 | P35320 | 297 | OXIR_STRLI Probable oxidoreductase OS=Strepto... | 288 | 9e-20 | 90.5 | 31 | 44 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 20 | Q8N5I4 | 330 | DHRSX_HUMAN Dehydrogenase/reductase SDR famil... | 296 | 1e-19 | 90.1 | 26 | 45 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 21 | O74959 | 339 | YJCD_SCHPO Uncharacterized oxidoreductase C73... | 208 | 2e-18 | 87 | 29 | 48 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 22 | Q8VBZ0 | 335 | DHRSX_MOUSE Dehydrogenase/reductase SDR famil... | 292 | 7e-18 | 85.5 | 32 | 45 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 23 | Q08651 | 330 | ENV9_YEAST Probable oxidoreductase ENV9 OS=Sa... | 150 | 0.000000000006 | 68.6 | 35 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005811; C:lipid particle; IDA:SGD.::GO:0005773; C:vacuole; IMP:GOC. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006624; P:vacuolar protein processing; IMP:SGD.::GO:0007033; P:vacuole organization; IMP:SGD. | 24 | Q92247 | 412 | BLI4_NEUCR Putative oxidoreductase bli-4, mit... | 169 | 0.0000000002 | 64.7 | 30 | 44 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 25 | Q5SS80 | 376 | DHR13_MOUSE Dehydrogenase/reductase SDR famil... | 285 | 0.0000000003 | 63.9 | 27 | 42 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 26 | Q17QU7 | 377 | DHR13_BOVIN Dehydrogenase/reductase SDR famil... | 285 | 0.0000000007 | 62.8 | 27 | 42 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 27 | Q6UX07 | 377 | DHR13_HUMAN Dehydrogenase/reductase SDR famil... | 285 | 0.000000007 | 59.7 | 26 | 40 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 28 | Q62904 | 334 | DHB7_RAT 3-keto-steroid reductase OS=Rattus n... | 230 | 0.00000001 | 58.9 | 26 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000253; F:3-keto sterol reductase activity; IEA:EC.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005148; F:prolactin receptor binding; IMP:RGD. | | | | | | | | | | | 29 | O88736 | 334 | DHB7_MOUSE 3-keto-steroid reductase OS=Mus mu... | 229 | 0.0000004 | 54.3 | 26 | 42 | GO:0005783; C:endoplasmic reticulum; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000253; F:3-keto sterol reductase activity; IDA:MGI.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006695; P:cholesterol biosynthetic process; IDA:MGI. | 30 | Q8W3D9 | 402 | PORB_ORYSJ Protochlorophyllide reductase B, c... | 217 | 0.0000006 | 53.9 | 27 | 44 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016630; F:protochlorophyllide reductase activity; IEA:EC. | | | | | | | | | | GO:0015995; P:chlorophyll biosynthetic process; IEA:UniProtKB-KW.::GO:0015979; P:photosynthesis; IEA:UniProtKB-KW. | 31 | Q7Z9I4 | 253 | YCP6_SCHPO Uncharacterized oxidoreductase C66... | 267 | 0.0000007 | 53.1 | 23 | 37 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0033554; P:cellular response to stress; IEP:PomBase. |