rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q9VLU5 | 409 | WWOX_DROME WW domain-containing oxidoreductas... | 308 | 3e-24 | 105 | 29 | 45 | GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:FlyBase.::GO:0010212; P:response to ionizing radiation; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 2 | Q803A8 | 412 | WWOX_DANRE WW domain-containing oxidoreductas... | 307 | 4e-20 | 93.6 | 28 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 3 | Q5F389 | 414 | WWOX_CHICK WW domain-containing oxidoreductas... | 303 | 6e-20 | 92.8 | 28 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 4 | Q91WL8 | 414 | WWOX_MOUSE WW domain-containing oxidoreductas... | 305 | 2e-19 | 91.7 | 26 | 44 | GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.::GO:0006917; P:induction of apoptosis; IDA:MGI.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0001649; P:osteoblast differentiation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0048705; P:skeletal system morphogenesis; IMP:MGI.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 5 | Q8N5I4 | 330 | DHRSX_HUMAN Dehydrogenase/reductase SDR famil... | 308 | 7e-19 | 89 | 30 | 44 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 6 | Q5R9W5 | 414 | WWOX_PONAB WW domain-containing oxidoreductas... | 300 | 4e-18 | 87.8 | 28 | 43 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 7 | Q9NZC7 | 414 | WWOX_HUMAN WW domain-containing oxidoreductas... | 300 | 8e-18 | 87 | 28 | 43 | GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005739; C:mitochondrion; ISS:BHF-UCL.::GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0050662; F:coenzyme binding; TAS:UniProtKB.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; NAS:UniProtKB.::GO:0046983; F:protein dimerization activity; TAS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.::GO:0006917; P:induction of apoptosis; ISS:BHF-UCL.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0048705; P:skeletal system morphogenesis; ISS:BHF-UCL.::GO:0008202; P:steroid metabolic process; TAS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 8 | Q6RVV4 | 316 | TIC32_PEA Short-chain dehydrogenase TIC 32, c... | 311 | 0.00000000000002 | 76.3 | 24 | 44 | GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 9 | Q9ERI6 | 334 | RDH14_MOUSE Retinol dehydrogenase 14 OS=Mus m... | 312 | 0.00000000000003 | 75.9 | 27 | 47 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 10 | Q96NR8 | 316 | RDH12_HUMAN Retinol dehydrogenase 12 OS=Homo ... | 308 | 0.0000000000007 | 71.6 | 27 | 44 | GO:0005622; C:intracellular; IDA:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0045494; P:photoreceptor cell maintenance; TAS:UniProtKB.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0042572; P:retinol metabolic process; IDA:UniProtKB. | 11 | A2RVM0 | 322 | TIC32_ARATH Short-chain dehydrogenase TIC 32,... | 316 | 0.000000000002 | 70.5 | 23 | 41 | GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 12 | Q8BYK4 | 316 | RDH12_MOUSE Retinol dehydrogenase 12 OS=Mus m... | 304 | 0.00000000002 | 67.4 | 27 | 42 | GO:0005622; C:intracellular; ISS:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0042572; P:retinol metabolic process; ISS:UniProtKB.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 13 | Q9HBH5 | 336 | RDH14_HUMAN Retinol dehydrogenase 14 OS=Homo ... | 321 | 0.00000000002 | 67.4 | 23 | 42 | GO:0005783; C:endoplasmic reticulum; IDA:LIFEdb. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 14 | P59837 | 316 | RDH12_BOVIN Retinol dehydrogenase 12 OS=Bos t... | 311 | 0.00000000005 | 66.2 | 27 | 41 | GO:0005622; C:intracellular; ISS:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0042572; P:retinol metabolic process; ISS:UniProtKB.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 15 | Q8CEE7 | 334 | RDH13_MOUSE Retinol dehydrogenase 13 OS=Mus m... | 308 | 0.0000000003 | 64.3 | 26 | 43 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 16 | Q01289 | 399 | POR_PEA Protochlorophyllide reductase, chloro... | 278 | 0.000000003 | 61.2 | 26 | 44 | GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016630; F:protochlorophyllide reductase activity; IEA:EC. | | | | | | | | | | GO:0015995; P:chlorophyll biosynthetic process; IEA:UniProtKB-KW.::GO:0015979; P:photosynthesis; IEA:UniProtKB-KW. | 17 | Q8NBN7 | 331 | RDH13_HUMAN Retinol dehydrogenase 13 OS=Homo ... | 304 | 0.000000003 | 61.2 | 25 | 42 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 18 | Q42850 | 395 | PORB_HORVU Protochlorophyllide reductase B, c... | 279 | 0.000000004 | 60.8 | 25 | 42 | GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016630; F:protochlorophyllide reductase activity; IEA:EC. | | | | | | | | | | GO:0015995; P:chlorophyll biosynthetic process; IEA:UniProtKB-KW.::GO:0015979; P:photosynthesis; IEA:UniProtKB-KW. | 19 | Q9SDT1 | 398 | POR_DAUCA Protochlorophyllide reductase, chlo... | 251 | 0.000000007 | 60.1 | 27 | 45 | GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016630; F:protochlorophyllide reductase activity; IEA:EC. | | | | | | | | | | GO:0015995; P:chlorophyll biosynthetic process; IEA:UniProtKB-KW.::GO:0015979; P:photosynthesis; IEA:UniProtKB-KW. | 20 | Q42536 | 405 | PORA_ARATH Protochlorophyllide reductase A, c... | 247 | 0.000000008 | 60.1 | 26 | 43 | GO:0009941; C:chloroplast envelope; IDA:TAIR.::GO:0009534; C:chloroplast thylakoid; IDA:TAIR. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016630; F:protochlorophyllide reductase activity; NAS:TAIR. | | | | | | | | | | GO:0015995; P:chlorophyll biosynthetic process; IEA:UniProtKB-KW.::GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.::GO:0009723; P:response to ethylene stimulus; IEP:TAIR. | 21 | Q03326 | 298 | OXIR_STRAT Probable oxidoreductase OS=Strepto... | 285 | 0.000000009 | 59.3 | 27 | 42 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 22 | Q8VBZ0 | 335 | DHRSX_MOUSE Dehydrogenase/reductase SDR famil... | 310 | 0.00000002 | 58.9 | 30 | 41 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 23 | O74959 | 339 | YJCD_SCHPO Uncharacterized oxidoreductase C73... | 217 | 0.00000003 | 58.2 | 24 | 42 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 24 | P35320 | 297 | OXIR_STRLI Probable oxidoreductase OS=Strepto... | 299 | 0.00000005 | 57 | 28 | 40 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 25 | A0PJE2 | 317 | DHR12_HUMAN Dehydrogenase/reductase SDR famil... | 138 | 0.00000009 | 56.6 | 30 | 47 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 26 | Q9QYF1 | 316 | RDH11_MOUSE Retinol dehydrogenase 11 OS=Mus m... | 308 | 0.0000001 | 56.2 | 25 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0001917; C:photoreceptor inner segment; IDA:MGI. | | | | | | | | | | GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0016062; P:adaptation of rhodopsin mediated signaling; IMP:MGI.::GO:0042572; P:retinol metabolic process; ISS:UniProtKB. | 27 | Q41249 | 398 | PORA_CUCSA Protochlorophyllide reductase, chl... | 245 | 0.0000002 | 55.5 | 26 | 44 | GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016630; F:protochlorophyllide reductase activity; IEA:EC. | | | | | | | | | | GO:0015995; P:chlorophyll biosynthetic process; IEA:UniProtKB-KW.::GO:0015979; P:photosynthesis; IEA:UniProtKB-KW. | 28 | Q8TC12 | 318 | RDH11_HUMAN Retinol dehydrogenase 11 OS=Homo ... | 307 | 0.0000002 | 55.5 | 24 | 42 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0052650; F:NADP-retinol dehydrogenase activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0042574; P:retinal metabolic process; IDA:MGI.::GO:0042572; P:retinol metabolic process; ISS:UniProtKB.::GO:0008202; P:steroid metabolic process; TAS:Reactome. | 29 | Q8W3D9 | 402 | PORB_ORYSJ Protochlorophyllide reductase B, c... | 283 | 0.0000003 | 55.1 | 24 | 41 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016630; F:protochlorophyllide reductase activity; IEA:EC. | | | | | | | | | | GO:0015995; P:chlorophyll biosynthetic process; IEA:UniProtKB-KW.::GO:0015979; P:photosynthesis; IEA:UniProtKB-KW. | 30 | A6QP05 | 317 | DHR12_BOVIN Dehydrogenase/reductase SDR famil... | 139 | 0.000002 | 52.8 | 29 | 45 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 31 | Q39617 | 397 | POR_CHLRE Protochlorophyllide reductase, chlo... | 325 | 0.000003 | 52 | 25 | 41 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016630; F:protochlorophyllide reductase activity; IEA:EC. | | | | | | | | | | GO:0015995; P:chlorophyll biosynthetic process; IEA:UniProtKB-KW.::GO:0015979; P:photosynthesis; IEA:UniProtKB-KW. |