| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
361 | P51480 | 168 | CD2A1_MOUSE Cyclin-dependent kinase inhibitor... | 118 | 0.001 | 44.3 | 32 | 47 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005730; C:nucleolus; IDA:MGI.::GO:0005654; C:nucleoplasm; IDA:MGI. | | | | | | | | | | GO:0004861; F:cyclin-dependent protein kinase inhibitor activity; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI. | | | | | | | | | | GO:0007569; P:cell aging; IDA:MGI.::GO:0007050; P:cell cycle arrest; IDA:MGI.::GO:0008544; P:epidermis development; IMP:MGI.::GO:0045736; P:negative regulation of cyclin-dependent protein kinase activity; IDA:MGI.::GO:0033600; P:negative regulation of mammary gland epithelial cell proliferation; IMP:MGI.::GO:0060058; P:positive regulation of apoptotic process involved in mammary gland involution; IMP:MGI.::GO:2000111; P:positive regulation of macrophage apoptotic process; IGI:BHF-UCL.::GO:0034393; P:positive regulation of smooth muscle cell apoptotic process; IGI:BHF-UCL.::GO:0046822; P:regulation of nucleocytoplasmic transport; IGI:MGI.::GO:0009303; P:rRNA transcription; IGI:MGI.::GO:0035019; P:somatic stem cell maintenance; IGI:MGI. | 362 | Q8MJ50 | 214 | OSTF1_BOVIN Osteoclast-stimulating factor 1 O... | 108 | 0.001 | 45.1 | 36 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 363 | Q96AX9 | 1013 | MIB2_HUMAN E3 ubiquitin-protein ligase MIB2 O... | 185 | 0.09 | 40.4 | 26 | 41 | GO:0005768; C:endosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IMP:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB. | 364 | Q5UQ04 | 287 | YR791_MIMIV Putative ankyrin repeat protein R... | 156 | 0.001 | 45.4 | 29 | 47 | | | | | | | | | | | | | | | | | | | | | | 365 | Q8R516 | 973 | MIB2_MOUSE E3 ubiquitin-protein ligase MIB2 O... | 185 | 0.033 | 42 | 26 | 41 | GO:0005769; C:early endosome; IDA:MGI.::GO:0000151; C:ubiquitin ligase complex; IDA:MGI. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW. | 366 | Q17QS6 | 329 | ASB5_BOVIN Ankyrin repeat and SOCS box protei... | 94 | 0.11 | 39.7 | 36 | 49 | | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 367 | Q3SWY2 | 452 | ILK_BOVIN Integrin-linked protein kinase OS=B... | 98 | 0.001 | 45.8 | 33 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009966; P:regulation of signal transduction; IEA:InterPro. | 368 | Q13418 | 452 | ILK_HUMAN Integrin-linked protein kinase OS=H... | 98 | 0.002 | 45.8 | 33 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0034329; P:cell junction assembly; TAS:Reactome.::GO:0008283; P:cell proliferation; NAS:UniProtKB.::GO:0007160; P:cell-matrix adhesion; NAS:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; NAS:UniProtKB.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0042327; P:positive regulation of phosphorylation; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0034446; P:substrate adhesion-dependent cell spreading; IMP:UniProtKB. | 369 | Q91XL9 | 950 | OSBL1_MOUSE Oxysterol-binding protein-related... | 199 | 0.002 | 46.2 | 30 | 40 | GO:0005770; C:late endosome; ISS:UniProtKB. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0006869; P:lipid transport; IEA:UniProtKB-KW. | 370 | Q1RJR6 | 273 | Y317_RICBR Putative ankyrin repeat protein RB... | 170 | 0.15 | 38.9 | 28 | 45 | | | | | | | | | | | | | | | | | | | | | | 371 | Q5R5V4 | 452 | ILK_PONAB Integrin-linked protein kinase OS=P... | 98 | 0.002 | 45.8 | 33 | 47 | GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009966; P:regulation of signal transduction; IEA:InterPro. | 372 | Q90623 | 1004 | MYPT1_CHICK Protein phosphatase 1 regulatory ... | 94 | 1.2 | 37 | 33 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0072357; C:PTW/PP1 phosphatase complex; ISS:UniProtKB. | | | | | | | | | | GO:0071889; F:14-3-3 protein binding; ISS:UniProtKB.::GO:0019208; F:phosphatase regulator activity; ISS:UniProtKB. | | | | | | | | | | GO:0030155; P:regulation of cell adhesion; ISS:UniProtKB.::GO:0035507; P:regulation of myosin-light-chain-phosphatase activity; ISS:UniProtKB. | 373 | Q54HW1 | 232 | PSD10_DICDI 26S proteasome non-ATPase regulat... | 138 | 0.002 | 44.7 | 30 | 43 | | | | | | | | | | | | | | | | | | | | | | 374 | Q8WWX0 | 329 | ASB5_HUMAN Ankyrin repeat and SOCS box protei... | 99 | 0.41 | 37.7 | 34 | 45 | | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 375 | P57044 | 451 | ILK_CAVPO Integrin-linked protein kinase OS=C... | 98 | 0.002 | 45.8 | 33 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 376 | Q99J82 | 452 | ILK_RAT Integrin-linked protein kinase OS=Rat... | 98 | 0.002 | 45.8 | 33 | 47 | GO:0005911; C:cell-cell junction; IDA:RGD.::GO:0043034; C:costamere; IDA:RGD.::GO:0043198; C:dendritic shaft; IDA:RGD.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0043195; C:terminal button; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005178; F:integrin binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD.::GO:0017124; F:SH3 domain binding; IDA:RGD.::GO:0004871; F:signal transducer activity; IDA:RGD. | | | | | | | | | | GO:0007569; P:cell aging; IMP:RGD.::GO:0007050; P:cell cycle arrest; IMP:RGD.::GO:0043206; P:fibril organization; IMP:RGD.::GO:0007229; P:integrin-mediated signaling pathway; IMP:RGD.::GO:0032288; P:myelin assembly; IMP:RGD.::GO:0010667; P:negative regulation of cardiac muscle cell apoptotic process; IMP:RGD.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:RGD.::GO:0006469; P:negative regulation of protein kinase activity; IMP:RGD.::GO:0014912; P:negative regulation of smooth muscle cell migration; IMP:RGD.::GO:0048662; P:negative regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0048812; P:neuron projection morphogenesis; IMP:RGD.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:RGD.::GO:0045773; P:positive regulation of axon extension; IMP:RGD.::GO:0030335; P:positive regulation of cell migration; IMP:RGD.::GO:0008284; P:positive regulation of cell proliferation; IMP:RGD.::GO:0001954; P:positive regulation of cell-matrix adhesion; IMP:RGD.::GO:0050775; P:positive regulation of dendrite morphogenesis; IMP:RGD.::GO:0043406; P:positive regulation of MAP kinase activity; IMP:RGD.::GO:0043410; P:positive regulation of MAPK cascade; IMP:RGD.::GO:0045663; P:positive regulation of myoblast differentiation; IMP:RGD.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:RGD.::GO:0051291; P:protein heterooligomerization; IDA:RGD.::GO:0032956; P:regulation of actin cytoskeleton organization; IMP:RGD.::GO:0034446; P:substrate adhesion-dependent cell spreading; IMP:RGD. | 377 | O55222 | 452 | ILK_MOUSE Integrin-linked protein kinase OS=M... | 98 | 0.002 | 45.8 | 33 | 47 | GO:0005925; C:focal adhesion; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0001658; P:branching involved in ureteric bud morphogenesis; IDA:MGI.::GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; IMP:MGI.::GO:0030513; P:positive regulation of BMP signaling pathway; IMP:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IMP:MGI.::GO:0045669; P:positive regulation of osteoblast differentiation; IMP:BHF-UCL. | 378 | Q6RI86 | 1125 | TRPA1_RAT Transient receptor potential cation... | 129 | 2.3 | 35.8 | 27 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 379 | Q8C0J6 | 512 | SWAHC_MOUSE Ankyrin repeat domain-containing ... | 115 | 1 | 37 | 31 | 51 | | | | | | | | | | | | | | | | | | | | | | 380 | Q8K4M9 | 950 | OSBL1_RAT Oxysterol-binding protein-related p... | 199 | 0.002 | 45.8 | 30 | 41 | GO:0005770; C:late endosome; ISS:UniProtKB. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0006869; P:lipid transport; IEA:UniProtKB-KW. | 381 | Q9FY48 | 1625 | KEG_ARATH E3 ubiquitin-protein ligase KEG OS=... | 68 | 2 | 36.2 | 35 | 54 | GO:0005769; C:early endosome; IDA:TAIR.::GO:0005802; C:trans-Golgi network; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043621; F:protein self-association; IPI:TAIR.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009738; P:abscisic acid mediated signaling pathway; IMP:TAIR.::GO:0006952; P:defense response; IMP:TAIR.::GO:0048589; P:developmental growth; IMP:TAIR.::GO:0009788; P:negative regulation of abscisic acid mediated signaling pathway; IMP:TAIR. | 382 | Q5UPB4 | 222 | YL036_MIMIV Putative ankyrin repeat protein L... | 109 | 4 | 34.3 | 29 | 46 | | | | | | | | | | | | | | | | | | | | | | 383 | Q876L5 | 763 | AKR1_SACBA Palmitoyltransferase AKR1 OS=Sacch... | 94 | 0.002 | 45.8 | 34 | 51 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 384 | Q6P1S6 | 118 | MTPN_XENTR Myotrophin OS=Xenopus tropicalis (... | 88 | 0.002 | 42.7 | 36 | 52 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 385 | Q8CGB3 | 1411 | UACA_MOUSE Uveal autoantigen with coiled-coil... | 111 | 5.6 | 34.7 | 30 | 44 | GO:0043293; C:apoptosome; IDA:MGI.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005635; C:nuclear envelope; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IMP:MGI.::GO:0008631; P:induction of apoptosis by oxidative stress; IMP:MGI.::GO:0050728; P:negative regulation of inflammatory response; IMP:MGI.::GO:0042347; P:negative regulation of NF-kappaB import into nucleus; IMP:MGI.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:MGI.::GO:0042307; P:positive regulation of protein import into nucleus; IMP:MGI.::GO:0009411; P:response to UV; IMP:MGI. | 386 | Q80T11 | 461 | USH1G_MOUSE Usher syndrome type-1G protein ho... | 122 | 0.002 | 45.4 | 32 | 52 | GO:0015629; C:actin cytoskeleton; IDA:HGNC.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042803; F:protein homodimerization activity; IPI:MGI. | | | | | | | | | | GO:0042472; P:inner ear morphogenesis; IMP:MGI.::GO:0060113; P:inner ear receptor cell differentiation; IMP:MGI.::GO:0007605; P:sensory perception of sound; IMP:MGI. | 387 | Q9BXX2 | 1392 | AN30B_HUMAN Ankyrin repeat domain-containing ... | 134 | 1.1 | 37 | 30 | 44 | | | | | | | | | | | | | | | | | | | | | | 388 | Q8BLA8 | 1125 | TRPA1_MOUSE Transient receptor potential cati... | 97 | 0.017 | 43.1 | 32 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0032421; C:stereocilium bundle; IDA:MGI. | | | | | | | | | | GO:0005262; F:calcium channel activity; IDA:MGI. | | | | | | | | | | GO:0050968; P:detection of chemical stimulus involved in sensory perception of pain; IDA:MGI.::GO:0050966; P:detection of mechanical stimulus involved in sensory perception of pain; IMP:MGI.::GO:0009409; P:response to cold; IDA:MGI.::GO:0042493; P:response to drug; IDA:MGI.::GO:0042542; P:response to hydrogen peroxide; IMP:MGI.::GO:0048265; P:response to pain; IDA:MGI.::GO:0050955; P:thermoception; IDA:MGI. | 389 | Q5ZJJ9 | 202 | OSTF1_CHICK Osteoclast-stimulating factor 1 O... | 88 | 0.012 | 42 | 40 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 390 | Q8MJ49 | 214 | OSTF1_PIG Osteoclast-stimulating factor 1 OS=... | 108 | 0.003 | 43.9 | 35 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 391 | Q3UES3 | 1166 | TNKS2_MOUSE Tankyrase-2 OS=Mus musculus (Mous... | 79 | 0.98 | 37.4 | 33 | 52 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003950; F:NAD+ ADP-ribosyltransferase activity; ISS:UniProtKB. | | | | | | | | | | GO:0035264; P:multicellular organism growth; IMP:MGI.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0070213; P:protein auto-ADP-ribosylation; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0040014; P:regulation of multicellular organism growth; IMP:MGI.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. |
