| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
331 | Q2KJB5 | 505 | NOSTN_BOVIN Nostrin OS=Bos taurus (Bovine). G... | 60 | 0.0002 | 49.3 | 32 | 52 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 332 | P20929 | 6669 | NEBU_HUMAN Nebulin OS=Homo sapiens (Human). G... | 128 | 0.0002 | 49.7 | 29 | 41 | GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030018; C:Z disc; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0008307; F:structural constituent of muscle; TAS:ProtInc. | | | | | | | | | | GO:0030049; P:muscle filament sliding; TAS:Reactome.::GO:0007517; P:muscle organ development; TAS:ProtInc.::GO:0030832; P:regulation of actin filament length; NAS:UniProtKB.::GO:0007525; P:somatic muscle development; NAS:UniProtKB. | 333 | O93436 | 468 | STAM2_CHICK Signal transducing adapter molecu... | 49 | 0.0002 | 48.9 | 43 | 63 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 334 | Q5HYK7 | 790 | SH319_HUMAN SH3 domain-containing protein 19 ... | 55 | 0.039 | 42 | 33 | 53 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:BHF-UCL. | | | | | | | | | | GO:0070064; F:proline-rich region binding; IPI:BHF-UCL. | | | | | | | | | | GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IMP:BHF-UCL.::GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.::GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB. | 335 | Q08DP6 | 785 | RHG10_BOVIN Rho GTPase-activating protein 10 ... | 67 | 0.0002 | 49.3 | 37 | 55 | GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 336 | P09324 | 541 | YES_CHICK Tyrosine-protein kinase Yes OS=Gall... | 100 | 0.0002 | 48.9 | 33 | 47 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 337 | P0CF33 | 103 | SD25N_YEAST Truncated guanine nucleotide exch... | 61 | 0.0002 | 45.8 | 38 | 51 | | | | | | | | | | | | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. | 338 | Q80Y61 | 522 | BI2L2_MOUSE Brain-specific angiogenesis inhib... | 113 | 0.0002 | 48.9 | 31 | 48 | GO:0044291; C:cell-cell contact zone; ISS:UniProtKB.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IDA:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0016044; P:cellular membrane organization; IDA:UniProtKB.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 339 | A1A4S6 | 786 | RHG10_HUMAN Rho GTPase-activating protein 10 ... | 67 | 0.0003 | 48.9 | 37 | 55 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 340 | Q62662 | 506 | FRK_RAT Tyrosine-protein kinase FRK OS=Rattus... | 92 | 0.0003 | 48.9 | 33 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0030154; P:cell differentiation; IEP:RGD. | 341 | P07947 | 543 | YES_HUMAN Tyrosine-protein kinase Yes OS=Homo... | 55 | 0.0003 | 48.9 | 42 | 53 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0044325; F:ion channel binding; IPI:BHF-UCL.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:BHF-UCL. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0043114; P:regulation of vascular permeability; TAS:BHF-UCL.::GO:0031295; P:T cell costimulation; TAS:Reactome. | 342 | O89032 | 1124 | SPD2A_MOUSE SH3 and PX domain-containing prot... | 49 | 5.5 | 35 | 29 | 49 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0002102; C:podosome; ISS:UniProtKB. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 343 | O97902 | 1129 | ASAP1_BOVIN Arf-GAP with SH3 domain, ANK repe... | 68 | 0.0003 | 49.3 | 34 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 344 | O14259 | 415 | YFP2_SCHPO SH3 domain-containing protein C7D4... | 60 | 0.0003 | 48.5 | 38 | 55 | GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0005515; F:protein binding; IPI:PomBase. | | | | | | | | | | GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:2000157; P:negative regulation of ubiquitin-specific protease activity; IMP:PomBase. | 345 | F1LM93 | 541 | YES_RAT Tyrosine-protein kinase Yes OS=Rattus... | 55 | 0.0003 | 48.9 | 42 | 53 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005154; F:epidermal growth factor receptor binding; IPI:RGD.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; IDA:RGD. | 346 | Q5ZJJ9 | 202 | OSTF1_CHICK Osteoclast-stimulating factor 1 O... | 48 | 0.0003 | 47 | 42 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 347 | Q06449 | 215 | PIN3_YEAST [PSI+] inducibility protein 3 OS=S... | 59 | 0.0003 | 47 | 34 | 51 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IPI:SGD. | 348 | P10936 | 537 | YES_XENLA Tyrosine-protein kinase Yes OS=Xeno... | 97 | 0.0003 | 48.5 | 34 | 45 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 349 | Q04736 | 541 | YES_MOUSE Tyrosine-protein kinase Yes OS=Mus ... | 55 | 0.0003 | 48.5 | 42 | 53 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0015758; P:glucose transport; IDA:MGI. | 350 | P00527 | 528 | YES_AVISY Tyrosine-protein kinase transformin... | 107 | 0.0003 | 48.5 | 35 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 351 | P34416 | 335 | LASP1_CAEEL LIM and SH3 domain protein F42H10... | 51 | 0.0003 | 47.8 | 39 | 59 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 352 | A8PWF6 | 1322 | MYO1_MALGO Myosin-1 OS=(Dandruff-associated f... | 52 | 0.0004 | 48.5 | 37 | 58 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 353 | P16333 | 377 | NCK1_HUMAN Cytoplasmic protein NCK1 OS=Homo s... | 109 | 0.016 | 42.7 | 29 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; NAS:UniProtKB.::GO:0005102; F:receptor binding; IPI:UniProtKB.::GO:0030159; F:receptor signaling complex scaffold activity; NAS:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:UniProtKB.::GO:0042102; P:positive regulation of T cell proliferation; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0007172; P:signal complex assembly; NAS:UniProtKB.::GO:0042110; P:T cell activation; IMP:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. | 354 | O08539 | 588 | BIN1_MOUSE Myc box-dependent-interacting prot... | 126 | 0.0004 | 48.1 | 31 | 41 | GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0042692; P:muscle cell differentiation; IMP:MGI. | 355 | Q8WUF5 | 828 | IASPP_HUMAN RelA-associated inhibitor OS=Homo... | 92 | 0.0004 | 48.5 | 32 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:ProtInc. | | | | | | | | | | GO:0003714; F:transcription corepressor activity; TAS:ProtInc.::GO:0008134; F:transcription factor binding; TAS:ProtInc. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 356 | Q7Z8J6 | 1282 | MYO1_USTMA Myosin-1 OS=Ustilago maydis (strai... | 60 | 0.0004 | 48.5 | 38 | 57 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 357 | P12931 | 536 | SRC_HUMAN Proto-oncogene tyrosine-protein kin... | 101 | 0.0005 | 47.8 | 29 | 42 | GO:0005901; C:caveola; IDA:BHF-UCL.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005743; C:mitochondrial inner membrane; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0020037; F:heme binding; IDA:UniProtKB.::GO:0005178; F:integrin binding; TAS:BHF-UCL.::GO:0044325; F:ion channel binding; IPI:BHF-UCL.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:BHF-UCL.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0045453; P:bone resorption; ISS:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IDA:BHF-UCL.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.::GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0033625; P:positive regulation of integrin activation; TAS:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0045124; P:regulation of bone resorption; TAS:BHF-UCL.::GO:0043114; P:regulation of vascular permeability; TAS:BHF-UCL.::GO:0070555; P:response to interleukin-1; IMP:BHF-UCL.::GO:0007172; P:signal complex assembly; TAS:ProtInc.::GO:0031295; P:T cell costimulation; TAS:Reactome. | 358 | Q9UNF0 | 486 | PACN2_HUMAN Protein kinase C and casein kinas... | 55 | 0.0005 | 47.8 | 45 | 60 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005215; F:transporter activity; TAS:ProtInc. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 359 | P16885 | 1265 | PLCG2_HUMAN 1-phosphatidylinositol 4,5-bispho... | 55 | 0.0005 | 48.1 | 42 | 60 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0019722; P:calcium-mediated signaling; NAS:UniProtKB.::GO:0006661; P:phosphatidylinositol biosynthetic process; IDA:UniProtKB.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0051209; P:release of sequestered calcium ion into cytosol; IDA:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; TAS:UniProtKB. | 360 | Q6XZF7 | 1577 | DNMBP_HUMAN Dynamin-binding protein OS=Homo s... | 53 | 0.15 | 40 | 34 | 55 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 361 | B0BNA1 | 340 | SH3Y1_RAT SH3 domain-containing YSC84-like pr... | 54 | 0.0006 | 47.4 | 41 | 57 | | | | | | | | | | | | | | | | | | | | | |
