| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
301 | Q7TSG5 | 549 | SH321_MOUSE SH3 domain-containing protein 21 ... | 51 | 0.00004 | 51.6 | 37 | 61 | | | | | | | | | | | | | | | | | | | | | | 302 | Q5TCZ1 | 1133 | SPD2A_HUMAN SH3 and PX domain-containing prot... | 118 | 7.8 | 34.7 | 25 | 36 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0002102; C:podosome; IDA:UniProtKB. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0006801; P:superoxide metabolic process; IDA:UniProtKB. | 303 | P34092 | 1111 | MYOB_DICDI Myosin IB heavy chain OS=Dictyoste... | 52 | 0.00004 | 51.6 | 42 | 63 | GO:0042641; C:actomyosin; IDA:dictyBase.::GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0031252; C:cell leading edge; TAS:dictyBase.::GO:0097203; C:phagocytic cup lip; IDA:dictyBase.::GO:0030670; C:phagocytic vesicle membrane; IDA:dictyBase.::GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell.::GO:0016461; C:unconventional myosin complex; IDA:dictyBase. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:dictyBase.::GO:0030898; F:actin-dependent ATPase activity; IDA:dictyBase.::GO:0005524; F:ATP binding; IDA:dictyBase.::GO:0000146; F:microfilament motor activity; IDA:dictyBase.::GO:0032031; F:myosin I head/neck binding; IDA:dictyBase. | | | | | | | | | | GO:0033275; P:actin-myosin filament sliding; IDA:dictyBase.::GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0006887; P:exocytosis; IEP:dictyBase.::GO:0006909; P:phagocytosis; IMP:dictyBase.::GO:0051707; P:response to other organism; TAS:dictyBase. | 304 | P70297 | 548 | STAM1_MOUSE Signal transducing adapter molecu... | 96 | 0.00004 | 51.2 | 33 | 51 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 305 | P87379 | 229 | GRB2A_XENLA Growth factor receptor-bound prot... | 55 | 0.021 | 41.6 | 36 | 56 | GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005154; F:epidermal growth factor receptor binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB. | | | | | | | | | | GO:0007143; P:female meiosis; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 306 | O89100 | 322 | GRAP2_MOUSE GRB2-related adaptor protein 2 OS... | 90 | 0.00006 | 50.4 | 30 | 48 | GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | | 307 | Q8N157 | 1196 | AHI1_HUMAN Jouberin OS=Homo sapiens (Human). ... | 63 | 0.00006 | 51.2 | 43 | 56 | GO:0005912; C:adherens junction; IDA:UniProtKB.::GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; IDA:UniProtKB.::GO:0036038; C:TCTN-B9D complex; ISS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0042384; P:cilium assembly; ISS:UniProtKB.::GO:0035844; P:cloaca development; ISS:UniProtKB.::GO:0001947; P:heart looping; ISS:UniProtKB.::GO:0030902; P:hindbrain development; ISS:UniProtKB.::GO:0070121; P:Kupffer's vesicle development; ISS:UniProtKB.::GO:0070986; P:left/right axis specification; ISS:UniProtKB.::GO:0001738; P:morphogenesis of a polarized epithelium; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0071599; P:otic vesicle development; ISS:UniProtKB.::GO:0035845; P:photoreceptor cell outer segment organization; ISS:UniProtKB.::GO:0030862; P:positive regulation of polarized epithelial cell differentiation; ISS:UniProtKB.::GO:0002092; P:positive regulation of receptor internalization; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0039023; P:pronephric duct morphogenesis; ISS:UniProtKB.::GO:0039008; P:pronephric nephron tubule morphogenesis; ISS:UniProtKB.::GO:0050795; P:regulation of behavior; ISS:UniProtKB.::GO:0010842; P:retina layer formation; ISS:UniProtKB.::GO:0065001; P:specification of axis polarity; ISS:UniProtKB.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; ISS:UniProtKB.::GO:0016192; P:vesicle-mediated transport; ISS:UniProtKB. | 308 | O88811 | 523 | STAM2_MOUSE Signal transducing adapter molecu... | 53 | 0.00006 | 50.8 | 42 | 60 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 309 | Q9DC07 | 270 | LNEBL_MOUSE LIM zinc-binding domain-containin... | 80 | 0.00006 | 50.1 | 33 | 49 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 310 | P14317 | 486 | HCLS1_HUMAN Hematopoietic lineage cell-specif... | 51 | 0.00006 | 50.8 | 41 | 61 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc. | | | | | | | | | | GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; TAS:ProtInc.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; ISS:UniProtKB.::GO:0009725; P:response to hormone stimulus; ISS:UniProtKB. | 311 | P14234 | 517 | FGR_MOUSE Tyrosine-protein kinase Fgr OS=Mus ... | 120 | 0.00007 | 50.8 | 31 | 47 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0001784; F:phosphotyrosine binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IDA:UniProtKB. | | | | | | | | | | GO:0050830; P:defense response to Gram-positive bacterium; IMP:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007229; P:integrin-mediated signaling pathway; IMP:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.::GO:0050715; P:positive regulation of cytokine secretion; IDA:UniProtKB.::GO:0043306; P:positive regulation of mast cell degranulation; IDA:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; TAS:UniProtKB.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0045088; P:regulation of innate immune response; IMP:UniProtKB.::GO:0050764; P:regulation of phagocytosis; IMP:UniProtKB.::GO:0045859; P:regulation of protein kinase activity; IDA:UniProtKB. | 312 | Q9CX99 | 217 | GRAP_MOUSE GRB2-related adapter protein OS=Mu... | 64 | 0.33 | 37.7 | 28 | 55 | | | | | | | | | | | | | | | | | | | | | | 313 | Q6YKA8 | 211 | DRK_DROSI Protein E(sev)2B OS=Drosophila simu... | 55 | 0.00007 | 48.9 | 40 | 55 | GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005070; F:SH3/SH2 adaptor activity; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | | 314 | Q08012 | 211 | DRK_DROME Protein enhancer of sevenless 2B OS... | 55 | 0.00007 | 48.9 | 40 | 55 | GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005118; F:sevenless binding; IPI:FlyBase.::GO:0005070; F:SH3/SH2 adaptor activity; NAS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:FlyBase.::GO:0007256; P:activation of JNKK activity; NAS:UniProtKB.::GO:0008595; P:anterior/posterior axis specification, embryo; TAS:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; IGI:FlyBase.::GO:0008355; P:olfactory learning; IMP:FlyBase.::GO:0045678; P:positive regulation of R7 cell differentiation; IGI:FlyBase.::GO:0007265; P:Ras protein signal transduction; IPI:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0045500; P:sevenless signaling pathway; IGI:FlyBase.::GO:0007614; P:short-term memory; IMP:FlyBase.::GO:0008293; P:torso signaling pathway; TAS:FlyBase. | 315 | P39743 | 482 | RV167_YEAST Reduced viability upon starvation... | 54 | 0.00007 | 50.4 | 43 | 59 | GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051666; P:actin cortical patch localization; IMP:SGD.::GO:0006897; P:endocytosis; IMP:SGD.::GO:0060988; P:lipid tube assembly; IDA:SGD. | 316 | P27446 | 537 | FYN_XIPHE Tyrosine-protein kinase Fyn OS=Xiph... | 109 | 0.00008 | 50.4 | 28 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 317 | P42685 | 505 | FRK_HUMAN Tyrosine-protein kinase FRK OS=Homo... | 94 | 0.00009 | 50.4 | 34 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:ProtInc. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc. | 318 | Q3USJ8 | 740 | FCSD2_MOUSE FCH and double SH3 domains protei... | 75 | 0.00009 | 50.4 | 36 | 57 | | | | | | | | | | | | | | | | | | | | | | 319 | O75886 | 525 | STAM2_HUMAN Signal transducing adapter molecu... | 52 | 0.00009 | 50.4 | 42 | 62 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0016197; P:endosome transport; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome. | 320 | Q5A895 | 498 | HSE1_CANAL Class E vacuolar protein-sorting m... | 63 | 0.00009 | 50.1 | 48 | 59 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 321 | Q4P9Q7 | 335 | SHO1_USTMA High osmolarity signaling protein ... | 114 | 0.0001 | 49.7 | 32 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 322 | O77506 | 263 | LASP1_RABIT LIM and SH3 domain protein 1 OS=O... | 64 | 0.0001 | 49.3 | 38 | 52 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006811; P:ion transport; IEA:UniProtKB-KW. | 323 | Q5XHY7 | 523 | STAM2_RAT Signal transducing adapter molecule... | 52 | 0.0001 | 50.1 | 40 | 63 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 324 | O13154 | 448 | PACN2_CHICK Protein kinase C and casein kinas... | 63 | 0.0001 | 49.7 | 43 | 60 | GO:0005829; C:cytosol; ISS:AgBase.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; ISS:AgBase. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045806; P:negative regulation of endocytosis; ISS:AgBase. | 325 | Q3B7M5 | 260 | LASP1_BOVIN LIM and SH3 domain protein 1 OS=B... | 59 | 0.0001 | 48.9 | 41 | 54 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006811; P:ion transport; IEA:UniProtKB-KW. | 326 | P13406 | 537 | FYN_XENLA Tyrosine-protein kinase Fyn OS=Xeno... | 113 | 0.0001 | 49.7 | 27 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 327 | Q6TXD4 | 1580 | DNMBP_MOUSE Dynamin-binding protein OS=Mus mu... | 58 | 0.017 | 43.1 | 38 | 57 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 328 | Q6Y5D8 | 786 | RHG10_MOUSE Rho GTPase-activating protein 10 ... | 104 | 0.0002 | 49.7 | 31 | 47 | GO:0005829; C:cytosol; IMP:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; IPI:MGI.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; IMP:MGI.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 329 | P49710 | 486 | HCLS1_MOUSE Hematopoietic lineage cell-specif... | 50 | 0.0002 | 49.3 | 40 | 58 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0032403; F:protein complex binding; IPI:MGI.::GO:0017124; F:SH3 domain binding; IDA:MGI. | | | | | | | | | | GO:0030218; P:erythrocyte differentiation; IMP:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; IMP:UniProtKB.::GO:0009725; P:response to hormone stimulus; IDA:UniProtKB. | 330 | O94478 | 420 | MU137_SCHPO Meiotically up-regulated gene 137... | 65 | 0.0002 | 49.3 | 38 | 52 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0007126; P:meiosis; IEP:PomBase. | 331 | Q2KJB5 | 505 | NOSTN_BOVIN Nostrin OS=Bos taurus (Bovine). G... | 60 | 0.0002 | 49.3 | 32 | 52 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. |
