rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
181 | A1DFN5 | 603 | HSE1_NEOFI Class E vacuolar protein-sorting m... | 96 | 0.0000003 | 58.2 | 32 | 47 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 182 | Q1E878 | 612 | HSE1_COCIM Class E vacuolar protein-sorting m... | 55 | 0.0000004 | 57.8 | 42 | 60 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 183 | Q5BBL4 | 581 | HSE1_EMENI Class E vacuolar protein-sorting m... | 64 | 0.0000004 | 57.8 | 41 | 55 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 184 | Q8T390 | 369 | SH3G3_DROME Endophilin-A OS=Drosophila melano... | 61 | 0.0000005 | 57 | 38 | 64 | GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042171; F:lysophosphatidic acid acyltransferase activity; IDA:FlyBase. | | | | | | | | | | GO:0007269; P:neurotransmitter secretion; NAS:FlyBase.::GO:0050803; P:regulation of synapse structure and activity; IMP:FlyBase.::GO:0048488; P:synaptic vesicle endocytosis; IMP:FlyBase. | 185 | Q8I1I3 | 369 | SH3G3_DROER Endophilin-A OS=Drosophila erecta... | 61 | 0.0000005 | 57 | 38 | 64 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042171; F:lysophosphatidic acid acyltransferase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050803; P:regulation of synapse structure and activity; ISS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; ISS:UniProtKB. | 186 | O74352 | 466 | HOB1_SCHPO Protein hob1 OS=Schizosaccharomyce... | 55 | 0.0000005 | 57.4 | 45 | 65 | GO:0051285; C:cell cortex of cell tip; TAS:PomBase.::GO:0031097; C:medial cortex; TAS:PomBase. | | | | | | | | | | GO:0051020; F:GTPase binding; NAS:PomBase. | | | | | | | | | | GO:0030702; P:chromatin silencing at centromere; IMP:PomBase.::GO:0006348; P:chromatin silencing at telomere; IMP:PomBase.::GO:0007163; P:establishment or maintenance of cell polarity; IGI:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0006974; P:response to DNA damage stimulus; IGI:PomBase.::GO:0000723; P:telomere maintenance; IMP:PomBase. | 187 | Q2GT05 | 713 | HSE1_CHAGB Class E vacuolar protein-sorting m... | 55 | 0.0000005 | 57.8 | 44 | 56 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 188 | Q7S6J4 | 745 | HSE1_NEUCR Class E vacuolar protein-sorting m... | 60 | 0.0000006 | 57.8 | 45 | 57 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 189 | Q75DS3 | 443 | HSE1_ASHGO Class E vacuolar protein-sorting m... | 59 | 0.0000006 | 57 | 44 | 59 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 190 | Q09746 | 642 | BZZ1_SCHPO Protein BZZ1 OS=Schizosaccharomyce... | 74 | 0.0000006 | 57.4 | 41 | 57 | GO:0030479; C:actin cortical patch; ISS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007015; P:actin filament organization; ISS:PomBase.::GO:0006897; P:endocytosis; ISS:PomBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 191 | Q10199 | 670 | IMP2_SCHPO Septation protein imp2 OS=Schizosa... | 58 | 0.0000007 | 57.4 | 47 | 59 | GO:0005826; C:actomyosin contractile ring; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0005515; F:protein binding; IPI:PomBase. | | | | | | | | | | GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; IMP:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 192 | Q7T2D0 | 755 | SGSM3_DANRE Small G protein signaling modulat... | 54 | 0.0000007 | 57.4 | 41 | 67 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005097; F:Rab GTPase activator activity; IEA:InterPro. | | | | | | | | | | | 193 | Q9WVE9 | 1217 | ITSN1_RAT Intersectin-1 OS=Rattus norvegicus ... | 71 | 1.3 | 37 | 25 | 46 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0006887; P:exocytosis; TAS:RGD. | 194 | Q8C120 | 878 | SH3R3_MOUSE SH3 domain-containing RING finger... | 52 | 0.9 | 37.4 | 31 | 48 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 195 | Q8VCZ6 | 750 | SGSM3_MOUSE Small G protein signaling modulat... | 69 | 0.0000008 | 57.4 | 36 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005921; C:gap junction; IDA:UniProtKB. | | | | | | | | | | GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.::GO:0017137; F:Rab GTPase binding; ISS:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0045732; P:positive regulation of protein catabolic process; IDA:UniProtKB.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB. | 196 | Q6P6R7 | 749 | SGSM3_RAT Small G protein signaling modulator... | 69 | 0.0000008 | 57 | 36 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.::GO:0017137; F:Rab GTPase binding; ISS:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB. | 197 | Q8R550 | 709 | SH3K1_MOUSE SH3 domain-containing kinase-bind... | 53 | 0.00004 | 51.6 | 43 | 60 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB. | 198 | Q96B97 | 665 | SH3K1_HUMAN SH3 domain-containing kinase-bind... | 49 | 0.00008 | 50.4 | 41 | 59 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0007267; P:cell-cell signaling; NAS:UniProtKB.::GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB. | 199 | Q0U6X7 | 618 | HSE1_PHANO Class E vacuolar protein-sorting m... | 121 | 0.0000009 | 57 | 25 | 45 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 200 | O42287 | 1270 | ITSN1_XENLA Intersectin-1 OS=Xenopus laevis (... | 71 | 1.9 | 36.6 | 28 | 49 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 201 | O74749 | 373 | HSE1_SCHPO Class E vacuolar protein-sorting m... | 70 | 0.0000009 | 56.2 | 39 | 54 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0033565; C:ESCRT-0 complex; IPI:PomBase.::GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0031321; P:ascospore-type prospore assembly; IGI:PomBase.::GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0006900; P:membrane budding; IC:PomBase.::GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:PomBase. | 202 | Q925Q9 | 709 | SH3K1_RAT SH3 domain-containing kinase-bindin... | 53 | 0.00002 | 52.8 | 45 | 60 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0042981; P:regulation of apoptotic process; TAS:RGD.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB. | 203 | Q8I1C0 | 369 | SH3G3_DROPS Endophilin-A OS=Drosophila pseudo... | 63 | 0.0000009 | 56.2 | 35 | 62 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042171; F:lysophosphatidic acid acyltransferase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050803; P:regulation of synapse structure and activity; ISS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; ISS:UniProtKB. | 204 | A6H8I2 | 753 | SGSM3_XENLA Small G protein signaling modulat... | 69 | 0.0000009 | 57 | 36 | 59 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005097; F:Rab GTPase activator activity; IEA:InterPro. | | | | | | | | | | | 205 | P38753 | 452 | HSE1_YEAST Class E vacuolar protein-sorting m... | 53 | 0.000001 | 56.6 | 47 | 58 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0033565; C:ESCRT-0 complex; IPI:SGD. | | | | | | | | | | GO:0043130; F:ubiquitin binding; IDA:SGD. | | | | | | | | | | GO:0045324; P:late endosome to vacuole transport; IMP:SGD.::GO:0006623; P:protein targeting to vacuole; IMP:SGD. | 206 | Q8I190 | 369 | SH3G3_DROVI Endophilin-A OS=Drosophila virili... | 63 | 0.000001 | 55.8 | 35 | 62 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042171; F:lysophosphatidic acid acyltransferase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050803; P:regulation of synapse structure and activity; ISS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; ISS:UniProtKB. | 207 | Q4WHP5 | 584 | HSE1_ASPFU Class E vacuolar protein-sorting m... | 96 | 0.000001 | 56.6 | 31 | 46 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 208 | Q63356 | 1107 | MYO1E_RAT Unconventional myosin-Ie OS=Rattus ... | 53 | 0.000001 | 57 | 47 | 62 | GO:0005912; C:adherens junction; ISS:UniProtKB.::GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051015; F:actin filament binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042623; F:ATPase activity, coupled; ISS:UniProtKB.::GO:0005516; F:calmodulin binding; ISS:UniProtKB.::GO:0003774; F:motor activity; IEA:InterPro.::GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.::GO:0032403; F:protein complex binding; IDA:RGD. | | | | | | | | | | GO:0006897; P:endocytosis; ISS:UniProtKB.::GO:0032836; P:glomerular basement membrane development; ISS:UniProtKB.::GO:0003094; P:glomerular filtration; ISS:UniProtKB.::GO:0072015; P:glomerular visceral epithelial cell development; ISS:UniProtKB. | 209 | Q0CJU8 | 597 | HSE1_ASPTN Class E vacuolar protein-sorting m... | 55 | 0.000001 | 56.6 | 42 | 58 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 210 | Q96HU1 | 749 | SGSM3_HUMAN Small G protein signaling modulat... | 69 | 0.000001 | 56.6 | 35 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.::GO:0017137; F:Rab GTPase binding; IDA:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0032486; P:Rap protein signal transduction; IEP:UniProtKB. | 211 | Q9UKW4 | 847 | VAV3_HUMAN Guanine nucleotide exchange factor... | 50 | 0.000001 | 56.6 | 48 | 66 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; TAS:ProtInc.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0050853; P:B cell receptor signaling pathway; IMP:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0030890; P:positive regulation of B cell proliferation; IMP:UniProtKB.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0006974; P:response to DNA damage stimulus; IMP:UniProtKB.::GO:0042493; P:response to drug; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. |