| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q8K4D6 | 507 | CP4X1_RAT Cytochrome P450 4X1 OS=Rattus norve... | 312 | 1e-27 | 118 | 25 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 32 | P05183 | 504 | CP3A2_RAT Cytochrome P450 3A2 OS=Rattus norve... | 371 | 2e-27 | 118 | 26 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0032451; F:demethylase activity; IDA:RGD.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050649; F:testosterone 6-beta-hydroxylase activity; IMP:RGD. | | | | | | | | | | GO:0017144; P:drug metabolic process; IDA:RGD.::GO:0070989; P:oxidative demethylation; IDA:RGD. | 33 | P33268 | 503 | CP3A8_MACFA Cytochrome P450 3A8 OS=Macaca fas... | 468 | 2e-27 | 118 | 26 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 34 | Q86W10 | 505 | CP4Z1_HUMAN Cytochrome P450 4Z1 OS=Homo sapie... | 372 | 3e-27 | 117 | 25 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 35 | P79401 | 503 | CP3AT_PIG Cytochrome P450 3A29 OS=Sus scrofa ... | 348 | 4e-27 | 117 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 36 | P98187 | 520 | CP4F8_HUMAN Cytochrome P450 4F8 OS=Homo sapie... | 421 | 5e-27 | 117 | 24 | 44 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; TAS:ProtInc.::GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006693; P:prostaglandin metabolic process; TAS:ProtInc.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 37 | Q64581 | 497 | CP3AI_RAT Cytochrome P450 3A18 OS=Rattus norv... | 355 | 9e-27 | 116 | 25 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008390; F:testosterone 16-alpha-hydroxylase activity; IDA:RGD.::GO:0050649; F:testosterone 6-beta-hydroxylase activity; IDA:RGD. | | | | | | | | | | | 38 | P04800 | 504 | CP3A1_RAT Cytochrome P450 3A1 OS=Rattus norve... | 456 | 9e-27 | 116 | 25 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IDA:RGD.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0032451; F:demethylase activity; IDA:RGD.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050649; F:testosterone 6-beta-hydroxylase activity; IDA:RGD. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0017144; P:drug metabolic process; IDA:RGD.::GO:0070989; P:oxidative demethylation; IDA:RGD.::GO:0046686; P:response to cadmium ion; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD. | 39 | P79102 | 507 | CP3AS_BOVIN Cytochrome P450 3A28 OS=Bos tauru... | 352 | 2e-26 | 115 | 24 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 40 | O88833 | 509 | CP4AA_MOUSE Cytochrome P450 4A10 OS=Mus muscu... | 353 | 2e-26 | 115 | 24 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006631; P:fatty acid metabolic process; TAS:UniProtKB. | 41 | Q64409 | 503 | CP3AH_CAVPO Cytochrome P450 3A17 OS=Cavia por... | 348 | 2e-26 | 115 | 26 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 42 | Q9HB55 | 503 | CP343_HUMAN Cytochrome P450 3A43 OS=Homo sapi... | 482 | 2e-26 | 115 | 24 | 43 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 43 | Q07973 | 514 | CP24A_HUMAN 1,25-dihydroxyvitamin D(3) 24-hyd... | 454 | 2e-26 | 115 | 26 | 44 | GO:0005743; C:mitochondrial inner membrane; TAS:Reactome. | | | | | | | | | | GO:0030342; F:1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; TAS:UniProtKB. | | | | | | | | | | GO:0001649; P:osteoblast differentiation; IEP:BHF-UCL.::GO:0042369; P:vitamin D catabolic process; NAS:BHF-UCL.::GO:0070561; P:vitamin D receptor signaling pathway; IEP:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 44 | Q27518 | 515 | C13A2_CAEEL Putative cytochrome P450 CYP13A2 ... | 410 | 3e-26 | 115 | 23 | 44 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 45 | Q9W011 | 510 | C4D20_DROME Probable cytochrome P450 4d20 OS=... | 404 | 3e-26 | 114 | 21 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 46 | Q9VA27 | 535 | CP4C3_DROME Cytochrome P450 4c3 OS=Drosophila... | 241 | 3e-26 | 115 | 30 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 47 | Q9VYQ7 | 483 | CP311_DROME Probable cytochrome P450 311a1 OS... | 366 | 4e-26 | 114 | 24 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 48 | O16805 | 512 | CP4D1_DROSI Cytochrome P450 4d1 OS=Drosophila... | 373 | 5e-26 | 114 | 25 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 49 | O42563 | 518 | CP3AR_ONCMY Cytochrome P450 3A27 OS=Oncorhync... | 378 | 1e-25 | 113 | 27 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 50 | P78329 | 520 | CP4F2_HUMAN Leukotriene-B(4) omega-hydroxylas... | 402 | 2e-25 | 112 | 23 | 45 | GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; TAS:UniProtKB.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IDA:BHF-UCL.::GO:0052871; F:alpha-tocopherol omega-hydroxylase activity; IDA:UniProtKB.::GO:0008392; F:arachidonic acid epoxygenase activity; IDA:UniProtKB.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050051; F:leukotriene-B4 20-monooxygenase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0052872; F:tocotrienol omega-hydroxylase activity; IDA:UniProtKB.::GO:0047057; F:vitamin-K-epoxide reductase (warfarin-sensitive) activity; IMP:UniProtKB. | | | | | | | | | | GO:0017144; P:drug metabolic process; IMP:UniProtKB.::GO:0019373; P:epoxygenase P450 pathway; IDA:UniProtKB.::GO:0030195; P:negative regulation of blood coagulation; IMP:UniProtKB.::GO:0032304; P:negative regulation of icosanoid secretion; IMP:UniProtKB.::GO:0032305; P:positive regulation of icosanoid secretion; IMP:UniProtKB.::GO:0003095; P:pressure natriuresis; IEP:UniProtKB.::GO:0003091; P:renal water homeostasis; IEP:UniProtKB.::GO:0055078; P:sodium ion homeostasis; IEP:UniProtKB.::GO:0042360; P:vitamin E metabolic process; IDA:UniProtKB.::GO:0042371; P:vitamin K biosynthetic process; IMP:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 51 | P14580 | 510 | CP4A6_RABIT Cytochrome P450 4A6 OS=Oryctolagu... | 349 | 2e-25 | 112 | 23 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 52 | P20815 | 502 | CP3A5_HUMAN Cytochrome P450 3A5 OS=Homo sapie... | 459 | 3e-25 | 112 | 25 | 41 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; TAS:ProtInc. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0019825; F:oxygen binding; TAS:ProtInc. | | | | | | | | | | GO:0009822; P:alkaloid catabolic process; IDA:BHF-UCL.::GO:0042737; P:drug catabolic process; IDA:BHF-UCL.::GO:0070989; P:oxidative demethylation; IDA:BHF-UCL.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0008202; P:steroid metabolic process; TAS:ProtInc.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 53 | O46054 | 496 | C4AE1_DROME Cytochrome P450 4ae1 OS=Drosophil... | 395 | 3e-25 | 112 | 25 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 54 | A2RRT9 | 525 | CP4V2_RAT Cytochrome P450 4V2 OS=Rattus norve... | 396 | 3e-25 | 112 | 23 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0010430; P:fatty acid omega-oxidation; ISS:UniProtKB. | 55 | Q9VL92 | 526 | CP4E3_DROME Cytochrome P450 4e3 OS=Drosophila... | 380 | 3e-25 | 112 | 22 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 56 | Q08477 | 520 | CP4F3_HUMAN Leukotriene-B(4) omega-hydroxylas... | 465 | 4e-25 | 112 | 22 | 43 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0052871; F:alpha-tocopherol omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050051; F:leukotriene-B4 20-monooxygenase activity; IEA:EC. | | | | | | | | | | GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 57 | O70537 | 501 | CP3AV_MESAU Cytochrome P450 3A31 OS=Mesocrice... | 532 | 4e-25 | 111 | 23 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 58 | Q64417 | 503 | CP3AE_CAVPO Cytochrome P450 3A14 OS=Cavia por... | 361 | 5e-25 | 111 | 26 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 59 | Q64406 | 503 | CP3AF_CAVPO Cytochrome P450 3A15 OS=Cavia por... | 348 | 6e-25 | 111 | 25 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 60 | P33269 | 512 | CP4D1_DROME Cytochrome P450 4d1 OS=Drosophila... | 374 | 6e-25 | 111 | 25 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 61 | O09158 | 503 | CP3AP_MOUSE Cytochrome P450 3A25 OS=Mus muscu... | 511 | 7e-25 | 110 | 23 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | |
