| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P40977 | 899 | PLC1_SCHPO 1-phosphatidylinositol 4,5-bisphos... | 568 | 4e-49 | 187 | 28 | 44 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0044242; P:cellular lipid catabolic process; IC:PomBase.::GO:0034644; P:cellular response to UV; IMP:PomBase.::GO:0048017; P:inositol lipid-mediated signaling; IC:PomBase.::GO:0019220; P:regulation of phosphate metabolic process; ISS:PomBase. | 2 | Q2VRL0 | 637 | PLCZ1_CHICK 1-phosphatidylinositol 4,5-bispho... | 515 | 1e-45 | 175 | 29 | 42 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 3 | P10895 | 756 | PLCD1_BOVIN 1-phosphatidylinositol 4,5-bispho... | 515 | 2e-42 | 166 | 29 | 43 | | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 4 | P10688 | 756 | PLCD1_RAT 1-phosphatidylinositol 4,5-bisphosp... | 516 | 4e-42 | 165 | 29 | 42 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0031966; C:mitochondrial membrane; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD. | | | | | | | | | | GO:0005509; F:calcium ion binding; IDA:RGD.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:RGD.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:RGD.::GO:0005515; F:protein binding; IPI:RGD.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051482; P:elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger; IMP:RGD.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0032962; P:positive regulation of inositol trisphosphate biosynthetic process; IMP:RGD.::GO:0010701; P:positive regulation of norepinephrine secretion; IMP:RGD.::GO:0010044; P:response to aluminum ion; IEP:RGD.::GO:0051592; P:response to calcium ion; IMP:RGD.::GO:0055093; P:response to hyperoxia; IEP:RGD.::GO:0010243; P:response to organic nitrogen; IEP:RGD.::GO:0043434; P:response to peptide hormone stimulus; IMP:RGD.::GO:0034696; P:response to prostaglandin F stimulus; IEP:RGD. | 5 | P51178 | 756 | PLCD1_HUMAN 1-phosphatidylinositol 4,5-bispho... | 512 | 2e-41 | 163 | 28 | 43 | GO:0005737; C:cytoplasm; IDA:MGI. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0032794; F:GTPase activating protein binding; IPI:BHF-UCL.::GO:0004435; F:phosphatidylinositol phospholipase C activity; TAS:ProtInc.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0006644; P:phospholipid metabolic process; TAS:ProtInc. | 6 | O13433 | 1099 | PLC1_CANAX 1-phosphatidylinositol 4,5-bisphos... | 567 | 3e-41 | 164 | 26 | 40 | | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 7 | Q02158 | 801 | PLC_DICDI 1-phosphatidylinositol 4,5-bisphosp... | 541 | 1e-40 | 161 | 28 | 42 | | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IMP:dictyBase.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0032959; P:inositol trisphosphate biosynthetic process; IMP:dictyBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0050922; P:negative regulation of chemotaxis; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; TAS:dictyBase. | 8 | A5D6R3 | 784 | PLD3A_DANRE 1-phosphatidylinositol 4,5-bispho... | 507 | 3e-40 | 160 | 28 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 9 | Q8K2J0 | 785 | PLCD3_MOUSE 1-phosphatidylinositol 4,5-bispho... | 509 | 6e-39 | 156 | 28 | 42 | GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0001525; P:angiogenesis; IGI:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0060716; P:labyrinthine layer blood vessel development; IGI:MGI.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0042127; P:regulation of cell proliferation; IGI:MGI. | 10 | Q9NQ66 | 1216 | PLCB1_HUMAN 1-phosphatidylinositol 4,5-bispho... | 529 | 6e-39 | 157 | 28 | 42 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0000790; C:nuclear chromatin; ISS:BHF-UCL.::GO:0016607; C:nuclear speck; IDA:BHF-UCL. | | | | | | | | | | GO:0005516; F:calmodulin binding; IPI:BHF-UCL.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0005096; F:GTPase activator activity; IDA:BHF-UCL.::GO:0004435; F:phosphatidylinositol phospholipase C activity; NAS:UniProtKB.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:BHF-UCL.::GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0060466; P:activation of meiosis involved in egg activation; ISS:BHF-UCL.::GO:0021987; P:cerebral cortex development; ISS:BHF-UCL.::GO:0007213; P:G-protein coupled acetylcholine receptor signaling pathway; ISS:BHF-UCL.::GO:0051318; P:G1 phase; ISS:BHF-UCL.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:BHF-UCL.::GO:0007215; P:glutamate receptor signaling pathway; ISS:BHF-UCL.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:BHF-UCL.::GO:0070498; P:interleukin-1-mediated signaling pathway; IDA:BHF-UCL.::GO:0035722; P:interleukin-12-mediated signaling pathway; IDA:BHF-UCL.::GO:0035723; P:interleukin-15-mediated signaling pathway; IDA:BHF-UCL.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007613; P:memory; ISS:BHF-UCL.::GO:2000438; P:negative regulation of monocyte extravasation; ISS:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:BHF-UCL.::GO:0046488; P:phosphatidylinositol metabolic process; ISS:BHF-UCL.::GO:2000344; P:positive regulation of acrosome reaction; ISS:BHF-UCL.::GO:2000560; P:positive regulation of CD24 biosynthetic process; ISS:BHF-UCL.::GO:0048639; P:positive regulation of developmental growth; ISS:BHF-UCL.::GO:0040019; P:positive regulation of embryonic development; ISS:BHF-UCL.::GO:0032735; P:positive regulation of interleukin-12 production; ISS:BHF-UCL.::GO:0046330; P:positive regulation of JNK cascade; IDA:BHF-UCL.::GO:0045663; P:positive regulation of myoblast differentiation; ISS:BHF-UCL.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:BHF-UCL.::GO:0080154; P:regulation of fertilization; ISS:BHF-UCL.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; ISS:BHF-UCL.::GO:0007268; P:synaptic transmission; TAS:Reactome. | 11 | Q8R3B1 | 756 | PLCD1_MOUSE 1-phosphatidylinositol 4,5-bispho... | 513 | 9e-39 | 155 | 28 | 42 | GO:0005829; C:cytosol; IDA:MGI. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0001525; P:angiogenesis; IGI:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0060716; P:labyrinthine layer blood vessel development; IGI:MGI.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0042127; P:regulation of cell proliferation; IGI:MGI. | 12 | P10894 | 1216 | PLCB1_BOVIN 1-phosphatidylinositol 4,5-bispho... | 533 | 1e-38 | 156 | 29 | 43 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 13 | Q8N3E9 | 789 | PLCD3_HUMAN 1-phosphatidylinositol 4,5-bispho... | 502 | 1e-38 | 155 | 29 | 43 | GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 14 | Q9Z1B3 | 1216 | PLCB1_MOUSE 1-phosphatidylinositol 4,5-bispho... | 533 | 2e-38 | 155 | 29 | 43 | GO:0000790; C:nuclear chromatin; IDA:BHF-UCL.::GO:0016607; C:nuclear speck; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005516; F:calmodulin binding; ISS:BHF-UCL.::GO:0019899; F:enzyme binding; ISS:BHF-UCL.::GO:0005521; F:lamin binding; IPI:BHF-UCL.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:BHF-UCL.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:BHF-UCL.::GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0060466; P:activation of meiosis involved in egg activation; IDA:BHF-UCL.::GO:0007155; P:cell adhesion; IC:BHF-UCL.::GO:0021987; P:cerebral cortex development; IMP:BHF-UCL.::GO:0030218; P:erythrocyte differentiation; TAS:BHF-UCL.::GO:0045444; P:fat cell differentiation; IDA:BHF-UCL.::GO:0007213; P:G-protein coupled acetylcholine receptor signaling pathway; IMP:BHF-UCL.::GO:0051318; P:G1 phase; IDA:BHF-UCL.::GO:0000086; P:G2/M transition of mitotic cell cycle; IDA:BHF-UCL.::GO:0007215; P:glutamate receptor signaling pathway; IMP:BHF-UCL.::GO:0008286; P:insulin receptor signaling pathway; TAS:BHF-UCL.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; IDA:BHF-UCL.::GO:0035722; P:interleukin-12-mediated signaling pathway; ISS:BHF-UCL.::GO:0035723; P:interleukin-15-mediated signaling pathway; ISS:BHF-UCL.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0030225; P:macrophage differentiation; NAS:BHF-UCL.::GO:0007613; P:memory; IMP:BHF-UCL.::GO:0006397; P:mRNA processing; TAS:BHF-UCL.::GO:2000438; P:negative regulation of monocyte extravasation; IDA:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:BHF-UCL.::GO:0001556; P:oocyte maturation; NAS:BHF-UCL.::GO:0046488; P:phosphatidylinositol metabolic process; ISS:BHF-UCL.::GO:2000344; P:positive regulation of acrosome reaction; IMP:BHF-UCL.::GO:2000560; P:positive regulation of CD24 biosynthetic process; IDA:BHF-UCL.::GO:0048639; P:positive regulation of developmental growth; IMP:BHF-UCL.::GO:0040019; P:positive regulation of embryonic development; IMP:BHF-UCL.::GO:0032735; P:positive regulation of interleukin-12 production; IMP:BHF-UCL.::GO:0046330; P:positive regulation of JNK cascade; ISS:BHF-UCL.::GO:0045663; P:positive regulation of myoblast differentiation; IDA:BHF-UCL.::GO:0032417; P:positive regulation of sodium:hydrogen antiporter activity; NAS:BHF-UCL.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:BHF-UCL.::GO:0080154; P:regulation of fertilization; IMP:BHF-UCL.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IMP:BHF-UCL. | 15 | P21671 | 791 | PLCD4_BOVIN 1-phosphatidylinositol 4,5-bispho... | 536 | 2e-38 | 154 | 29 | 42 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 16 | P10687 | 1216 | PLCB1_RAT 1-phosphatidylinositol 4,5-bisphosp... | 377 | 4e-38 | 155 | 32 | 45 | GO:0005829; C:cytosol; IDA:RGD.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0016607; C:nuclear speck; ISS:BHF-UCL. | | | | | | | | | | GO:0005509; F:calcium ion binding; IDA:BHF-UCL.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:RGD.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0060466; P:activation of meiosis involved in egg activation; ISS:BHF-UCL.::GO:0021987; P:cerebral cortex development; ISS:BHF-UCL.::GO:0051318; P:G1 phase; ISS:BHF-UCL.::GO:0007215; P:glutamate receptor signaling pathway; ISS:BHF-UCL.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:BHF-UCL.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007612; P:learning; IEP:RGD.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007613; P:memory; IEP:RGD.::GO:2000438; P:negative regulation of monocyte extravasation; ISS:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:BHF-UCL.::GO:0046488; P:phosphatidylinositol metabolic process; IEP:RGD.::GO:2000560; P:positive regulation of CD24 biosynthetic process; ISS:BHF-UCL.::GO:0048639; P:positive regulation of developmental growth; ISS:BHF-UCL.::GO:0032735; P:positive regulation of interleukin-12 production; ISS:BHF-UCL.::GO:0045663; P:positive regulation of myoblast differentiation; ISS:BHF-UCL.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:BHF-UCL.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; ISS:BHF-UCL.::GO:0034284; P:response to monosaccharide stimulus; IDA:BHF-UCL.::GO:0010243; P:response to organic nitrogen; IEP:RGD.::GO:0043434; P:response to peptide hormone stimulus; IDA:BHF-UCL. | 17 | Q8SPR7 | 772 | PLCD4_PIG 1-phosphatidylinositol 4,5-bisphosp... | 507 | 5e-37 | 150 | 30 | 43 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 18 | Q86YW0 | 608 | PLCZ1_HUMAN 1-phosphatidylinositol 4,5-bispho... | 488 | 1e-36 | 148 | 28 | 41 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 19 | Q8K394 | 1128 | PLCL2_MOUSE Inactive phospholipase C-like pro... | 497 | 2e-36 | 149 | 27 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006629; P:lipid metabolic process; IEA:InterPro. | 20 | Q9UPR0 | 1127 | PLCL2_HUMAN Inactive phospholipase C-like pro... | 497 | 3e-36 | 149 | 27 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006629; P:lipid metabolic process; IEA:InterPro. | 21 | Q62711 | 772 | PLCD4_RAT 1-phosphatidylinositol 4,5-bisphosp... | 492 | 1e-35 | 146 | 28 | 43 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:RGD.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; TAS:RGD.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 22 | Q00722 | 1185 | PLCB2_HUMAN 1-phosphatidylinositol 4,5-bispho... | 492 | 2e-35 | 147 | 28 | 42 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; TAS:ProtInc.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; TAS:ProtInc.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0006644; P:phospholipid metabolic process; TAS:ProtInc.::GO:0007268; P:synaptic transmission; TAS:Reactome. | 23 | Q32NH8 | 758 | PLCD4_XENLA 1-phosphatidylinositol 4,5-bispho... | 519 | 2e-35 | 145 | 28 | 43 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 24 | Q8K4D7 | 647 | PLCZ1_MOUSE 1-phosphatidylinositol 4,5-bispho... | 470 | 4e-35 | 144 | 26 | 39 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006816; P:calcium ion transport; IDA:MGI.::GO:0007343; P:egg activation; IDA:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 25 | Q9BRC7 | 762 | PLCD4_HUMAN 1-phosphatidylinositol 4,5-bispho... | 517 | 6e-35 | 144 | 28 | 41 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 26 | Q5RET0 | 762 | PLCD4_PONAB 1-phosphatidylinositol 4,5-bispho... | 517 | 9e-35 | 143 | 28 | 41 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 27 | Q4R6L3 | 799 | PLCD4_MACFA 1-phosphatidylinositol 4,5-bispho... | 543 | 9e-35 | 144 | 27 | 39 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 28 | Q1RML2 | 634 | PLCZ1_BOVIN 1-phosphatidylinositol 4,5-bispho... | 372 | 2e-34 | 142 | 31 | 46 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 29 | Q5FX52 | 645 | PLCZ1_RAT 1-phosphatidylinositol 4,5-bisphosp... | 383 | 1e-33 | 139 | 29 | 43 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 30 | Q9QW07 | 1175 | PLCB4_RAT 1-phosphatidylinositol 4,5-bisphosp... | 416 | 5e-33 | 139 | 27 | 42 | GO:0005737; C:cytoplasm; IDA:RGD.::GO:0005626; C:insoluble fraction; IDA:RGD. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0051019; F:mitogen-activated protein kinase binding; IPI:RGD.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0043267; P:negative regulation of potassium ion transport; IMP:RGD.::GO:0007602; P:phototransduction; NAS:RGD. | 31 | Q15147 | 1175 | PLCB4_HUMAN 1-phosphatidylinositol 4,5-bispho... | 416 | 6e-33 | 138 | 27 | 42 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. |
