| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | A6N9I4 | 608 | GRP2_BOVIN RAS guanyl-releasing protein 2 OS=... | 204 | 0.0000000000001 | 79.3 | 29 | 49 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 92 | Q32N25 | 594 | GRP2A_XENLA RAS guanyl-releasing protein 2-A ... | 214 | 0.0000000000002 | 78.6 | 27 | 48 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 93 | Q7LDG7 | 609 | GRP2_HUMAN RAS guanyl-releasing protein 2 OS=... | 204 | 0.0000000000002 | 78.6 | 29 | 49 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; NAS:UniProtKB.::GO:0019992; F:diacylglycerol binding; NAS:UniProtKB.::GO:0005085; F:guanyl-nucleotide exchange factor activity; TAS:UniProtKB. | | | | | | | | | | GO:0030168; P:platelet activation; TAS:Reactome.::GO:0007265; P:Ras protein signal transduction; NAS:UniProtKB.::GO:0001558; P:regulation of cell growth; NAS:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro. | 94 | Q8VCC8 | 918 | RPGF3_MOUSE Rap guanine nucleotide exchange f... | 208 | 0.0000000000003 | 78.6 | 27 | 50 | GO:0005952; C:cAMP-dependent protein kinase complex; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.::GO:0008603; F:cAMP-dependent protein kinase regulator activity; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:MGI. | | | | | | | | | | GO:0001932; P:regulation of protein phosphorylation; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 95 | Q8N9B8 | 481 | RGF1A_HUMAN Ras-GEF domain-containing family ... | 386 | 0.0000000000006 | 76.6 | 23 | 43 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; IDA:UniProtKB. | | | | | | | | | | GO:0016477; P:cell migration; IDA:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 96 | Q8JZL7 | 473 | RGF1B_MOUSE Ras-GEF domain-containing family ... | 223 | 0.0000000000007 | 76.3 | 26 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 97 | P0C643 | 608 | GRP2_RAT RAS guanyl-releasing protein 2 OS=Ra... | 204 | 0.0000000000008 | 76.6 | 28 | 48 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 98 | Q6DCK3 | 594 | GRP2B_XENLA RAS guanyl-releasing protein 2-B ... | 214 | 0.0000000000008 | 76.3 | 27 | 48 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 99 | Q9QUG9 | 608 | GRP2_MOUSE RAS guanyl-releasing protein 2 OS=... | 204 | 0.000000000001 | 75.9 | 28 | 48 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 100 | Q5RC04 | 472 | RGF1B_PONAB Ras-GEF domain-containing family ... | 223 | 0.000000000003 | 74.3 | 26 | 46 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 101 | Q0VAM2 | 473 | RGF1B_HUMAN Ras-GEF domain-containing family ... | 223 | 0.000000000003 | 74.3 | 26 | 46 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; IDA:UniProtKB. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 102 | A4IFE4 | 472 | RGF1B_BOVIN Ras-GEF domain-containing family ... | 223 | 0.000000000004 | 73.9 | 26 | 46 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 103 | Q28EC1 | 472 | RGF1B_XENTR Ras-GEF domain-containing family ... | 223 | 0.000000000007 | 73.2 | 26 | 46 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 104 | P25300 | 642 | BUD5_YEAST Bud site selection protein 5 OS=Sa... | 39 | 0.17 | 40 | 46 | 69 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0000131; C:incipient cellular bud site; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; TAS:SGD. | | | | | | | | | | GO:0007120; P:axial cellular bud site selection; TAS:SGD.::GO:0007121; P:bipolar cellular bud site selection; TAS:SGD.::GO:0007124; P:pseudohyphal growth; TAS:SGD.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:SGD. | 105 | Q6CY10 | 1366 | LTE1_KLULA Guanine nucleotide exchange factor... | 185 | 0.0000000001 | 70.5 | 26 | 51 | GO:0005933; C:cellular bud; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 106 | P07866 | 1435 | LTE1_YEAST Guanine nucleotide exchange factor... | 190 | 0.000000001 | 67 | 27 | 48 | GO:0005933; C:cellular bud; IDA:SGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0031578; P:mitotic cell cycle spindle orientation checkpoint; TAS:SGD.::GO:0007096; P:regulation of exit from mitosis; TAS:SGD.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IGI:SGD. | 107 | Q6FT12 | 1318 | LTE1_CANGA Guanine nucleotide exchange factor... | 219 | 0.000000003 | 65.5 | 25 | 45 | GO:0005933; C:cellular bud; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 108 | Q75BH9 | 1439 | LTE1_ASHGO Guanine nucleotide exchange factor... | 229 | 0.00000001 | 63.5 | 23 | 45 | GO:0005933; C:cellular bud; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 109 | Q1LZ97 | 673 | GRP4_BOVIN RAS guanyl-releasing protein 4 OS=... | 169 | 0.00000002 | 62.4 | 29 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016049; P:cell growth; ISS:UniProtKB.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0046579; P:positive regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0009991; P:response to extracellular stimulus; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 110 | P34578 | 1038 | RPGF1_CAEEL Rap guanine nucleotide exchange f... | 179 | 0.00000005 | 61.6 | 25 | 49 | GO:0005952; C:cAMP-dependent protein kinase complex; IEA:InterPro. | | | | | | | | | | GO:0008603; F:cAMP-dependent protein kinase regulator activity; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0001932; P:regulation of protein phosphorylation; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 111 | Q8BTM9 | 673 | GRP4_MOUSE RAS guanyl-releasing protein 4 OS=... | 169 | 0.0000002 | 58.9 | 29 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016049; P:cell growth; ISS:UniProtKB.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0046579; P:positive regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0009991; P:response to extracellular stimulus; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 112 | Q8IV61 | 690 | GRP3_HUMAN Ras guanyl-releasing protein 3 OS=... | 180 | 0.0000006 | 57.8 | 26 | 47 | GO:0005887; C:integral to plasma membrane; NAS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; NAS:UniProtKB.::GO:0019992; F:diacylglycerol binding; NAS:UniProtKB.::GO:0046582; F:Rap GTPase activator activity; IDA:UniProtKB.::GO:0004871; F:signal transducer activity; TAS:UniProtKB. | | | | | | | | | | GO:0000165; P:MAPK cascade; NAS:UniProtKB. | 113 | Q8TDF6 | 673 | GRP4_HUMAN RAS guanyl-releasing protein 4 OS=... | 168 | 0.000001 | 57 | 29 | 47 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; TAS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0019992; F:diacylglycerol binding; TAS:UniProtKB.::GO:0030742; F:GTP-dependent protein binding; NAS:UniProtKB.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; IDA:UniProtKB. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; NAS:UniProtKB.::GO:0016049; P:cell growth; IDA:UniProtKB.::GO:0008283; P:cell proliferation; IDA:UniProtKB.::GO:0030099; P:myeloid cell differentiation; TAS:UniProtKB.::GO:0046579; P:positive regulation of Ras protein signal transduction; IDA:UniProtKB.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; NAS:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0009991; P:response to extracellular stimulus; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; NAS:UniProtKB. | 114 | Q8R5I4 | 678 | GRP4_RAT RAS guanyl-releasing protein 4 OS=Ra... | 169 | 0.000002 | 56.2 | 28 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016049; P:cell growth; ISS:UniProtKB.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0046579; P:positive regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0009991; P:response to extracellular stimulus; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 115 | Q76NI1 | 1749 | VKIND_HUMAN Protein very KIND OS=Homo sapiens... | 461 | 0.000009 | 54.3 | 21 | 37 | | | | | | | | | | | | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 116 | Q6NTL4 | 791 | GRP1_XENLA RAS guanyl-releasing protein 1 OS=... | 161 | 0.00007 | 50.8 | 27 | 47 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 117 | O95267 | 797 | GRP1_HUMAN RAS guanyl-releasing protein 1 OS=... | 170 | 0.00008 | 50.8 | 25 | 44 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005509; F:calcium ion binding; TAS:ProtInc.::GO:0005085; F:guanyl-nucleotide exchange factor activity; TAS:Reactome.::GO:0008289; F:lipid binding; TAS:ProtInc. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro. | 118 | A4IJ06 | 791 | GRP1_XENTR RAS guanyl-releasing protein 1 OS=... | 161 | 0.0001 | 50.4 | 27 | 47 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 119 | Q99P84 | 2281 | PLCE1_RAT 1-phosphatidylinositol 4,5-bisphosp... | 213 | 0.0002 | 50.1 | 24 | 42 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0004435; F:phosphatidylinositol phospholipase C activity; ISS:UniProtKB.::GO:0017016; F:Ras GTPase binding; IDA:RGD.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; ISS:UniProtKB.::GO:0007200; P:activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; ISS:UniProtKB.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007265; P:Ras protein signal transduction; IDA:RGD.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0046578; P:regulation of Ras protein signal transduction; ISS:UniProtKB. | 120 | Q8K4S1 | 2282 | PLCE1_MOUSE 1-phosphatidylinositol 4,5-bispho... | 213 | 0.0002 | 49.3 | 24 | 42 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0019899; F:enzyme binding; ISS:UniProtKB.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0004435; F:phosphatidylinositol phospholipase C activity; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; ISS:UniProtKB.::GO:0007200; P:activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger; ISS:UniProtKB.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.::GO:0046578; P:regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 121 | Q9R1K8 | 795 | GRP1_RAT RAS guanyl-releasing protein 1 OS=Ra... | 170 | 0.0003 | 48.9 | 25 | 43 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0017034; F:Rap guanyl-nucleotide exchange factor activity; TAS:RGD. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. |
