rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
151 | Q15811 | 1721 | ITSN1_HUMAN Intersectin-1 OS=Homo sapiens (Hu... | 97 | 0.15 | 40.4 | 32 | 43 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005905; C:coated pit; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; NAS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0070064; F:proline-rich region binding; IPI:UniProtKB.::GO:0032947; F:protein complex scaffold; IDA:UniProtKB.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0048488; P:synaptic vesicle endocytosis; TAS:ProtInc. | 152 | Q28E95 | 861 | SH3R1_XENTR E3 ubiquitin-protein ligase SH3RF... | 43 | 0.17 | 40 | 40 | 51 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 153 | Q12774 | 1597 | ARHG5_HUMAN Rho guanine nucleotide exchange f... | 39 | 0.19 | 40 | 38 | 56 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0005525; F:GTP binding; TAS:ProtInc.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 154 | Q9Z0R6 | 1659 | ITSN2_MOUSE Intersectin-2 OS=Mus musculus (Mo... | 49 | 0.2 | 40 | 39 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 155 | O42287 | 1270 | ITSN1_XENLA Intersectin-1 OS=Xenopus laevis (... | 46 | 0.21 | 39.7 | 39 | 52 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 156 | Q9NZM3 | 1697 | ITSN2_HUMAN Intersectin-2 OS=Homo sapiens (Hu... | 46 | 0.27 | 39.3 | 39 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 157 | A5D8S5 | 867 | SH3R1_DANRE E3 ubiquitin-protein ligase SH3RF... | 62 | 0.29 | 39.3 | 31 | 44 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 158 | A5D7F8 | 840 | SH3R1_BOVIN E3 ubiquitin-protein ligase SH3RF... | 43 | 0.31 | 39.3 | 40 | 51 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 159 | Q8TEJ3 | 882 | SH3R3_HUMAN SH3 domain-containing RING finger... | 39 | 0.4 | 38.9 | 38 | 54 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 160 | Q96DR7 | 871 | ARHGQ_HUMAN Rho guanine nucleotide exchange f... | 34 | 0.53 | 38.5 | 41 | 59 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 161 | A7TDZ8 | 1214 | MYO1_VANPO Myosin-1 OS=(Kluyveromyces polyspo... | 38 | 1.2 | 37.4 | 37 | 55 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 162 | P14564 | 717 | RPOC2_NOSCO DNA-directed RNA polymerase subun... | 100 | 1.2 | 37 | 28 | 47 | | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 163 | Q5UNW8 | 343 | YL719_MIMIV Uncharacterized protein L719 OS=A... | 90 | 2.2 | 35.8 | 28 | 44 | | | | | | | | | | | | | | | | | | | | | | 164 | Q99961 | 368 | SH3G1_HUMAN Endophilin-A2 OS=Homo sapiens (Hu... | 98 | 2.3 | 35.8 | 28 | 44 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:ProtInc. | 165 | Q28983 | 2476 | ZAN_PIG Zonadhesin OS=Sus scrofa (Pig). GN=ZA... | 159 | 2.3 | 36.6 | 28 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0050840; F:extracellular matrix binding; IDA:MGI. | | | | | | | | | | GO:0007339; P:binding of sperm to zona pellucida; IDA:MGI.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 166 | P29355 | 228 | SEM5_CAEEL Sex muscle abnormal protein 5 OS=C... | 77 | 2.4 | 35.4 | 30 | 44 | | | | | | | | | | | | | | | | | | | | | GO:0016477; P:cell migration; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0019915; P:lipid storage; IMP:WormBase.::GO:0030539; P:male genitalia development; IMP:WormBase.::GO:0007517; P:muscle organ development; IMP:WormBase.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0031344; P:regulation of cell projection organization; IMP:WormBase.::GO:0040028; P:regulation of vulval development; IMP:WormBase.::GO:0032940; P:secretion by cell; IMP:WormBase. | 167 | Q62419 | 368 | SH3G1_MOUSE Endophilin-A2 OS=Mus musculus (Mo... | 104 | 3.3 | 35.4 | 23 | 43 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 168 | O35964 | 368 | SH3G1_RAT Endophilin-A2 OS=Rattus norvegicus ... | 101 | 3.6 | 35.4 | 26 | 46 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0051020; F:GTPase binding; IPI:RGD.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0019902; F:phosphatase binding; IPI:RGD. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 169 | Q9LRR5 | 1424 | DRL21_ARATH Putative disease resistance prote... | 88 | 4.1 | 35.4 | 32 | 44 | | | | | | | | | | | GO:0043531; F:ADP binding; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006952; P:defense response; IEA:UniProtKB-KW. | 170 | P0CF33 | 103 | SD25N_YEAST Truncated guanine nucleotide exch... | 53 | 4.2 | 32.7 | 36 | 47 | | | | | | | | | | | | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. | 171 | Q6FN18 | 1217 | MYO5_CANGA Myosin-5 OS=NRRL Y-65) (Yeast) (To... | 37 | 4.9 | 35.4 | 35 | 54 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 172 | Q8BWA8 | 802 | ARHGJ_MOUSE Rho guanine nucleotide exchange f... | 37 | 5.3 | 35 | 35 | 62 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0032321; P:positive regulation of Rho GTPase activity; IGI:MGI.::GO:0042060; P:wound healing; IMP:MGI. | 173 | Q555L8 | 389 | Y4695_DICDI SH3 and FCH domain-containing pro... | 50 | 6 | 34.7 | 38 | 54 | | | | | | | | | | | | | | | | | | | | | | 174 | Q2KJA1 | 368 | SH3G1_BOVIN Endophilin-A2 OS=Bos taurus (Bovi... | 98 | 6.6 | 34.3 | 27 | 44 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 175 | Q9KC68 | 174 | RACA_BACHD Chromosome-anchoring protein racA ... | 61 | 7.2 | 33.5 | 33 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW. | 176 | B2UQR9 | 314 | FMT_AKKM8 Methionyl-tRNA formyltransferase OS... | 85 | 8 | 33.9 | 32 | 49 | | | | | | | | | | | GO:0004479; F:methionyl-tRNA formyltransferase activity; IEA:EC.::GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 177 | Q84L33 | 371 | RD23A_ARATH Putative DNA repair protein RAD23... | 89 | 9.2 | 33.9 | 27 | 54 | GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0070628; F:proteasome binding; IDA:TAIR.::GO:0043130; F:ubiquitin binding; IDA:TAIR. | | | | | | | | | | GO:0006289; P:nucleotide-excision repair; IEA:InterPro.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IEA:InterPro. |