| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | Q54JG7 | 485 | DST4_DICDI Serine/threonine-protein kinase ds... | 272 | 5e-38 | 154 | 33 | 53 | GO:0005737; C:cytoplasm; ISS:dictyBase.::GO:0005634; C:nucleus; ISS:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:dictyBase.::GO:0008283; P:cell proliferation; ISS:dictyBase.::GO:0007165; P:signal transduction; ISS:dictyBase. | 62 | Q8T0S6 | 669 | HIPPO_DROME Serine/threonine-protein kinase h... | 321 | 5e-38 | 156 | 32 | 51 | GO:0016020; C:membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004702; F:receptor signaling protein serine/threonine kinase activity; NAS:FlyBase. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:UniProtKB.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; IGI:FlyBase.::GO:0035329; P:hippo signaling cascade; TAS:UniProtKB.::GO:0002011; P:morphogenesis of an epithelial sheet; IMP:FlyBase.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; IMP:FlyBase.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:FlyBase.::GO:0046621; P:negative regulation of organ growth; TAS:FlyBase.::GO:0045464; P:R8 cell fate specification; IMP:FlyBase.::GO:0010212; P:response to ionizing radiation; IMP:FlyBase.::GO:0072089; P:stem cell proliferation; IDA:FlyBase. | 63 | Q6P3Q4 | 485 | STK4_XENTR Serine/threonine-protein kinase 4 ... | 274 | 6e-38 | 154 | 33 | 54 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB. | 64 | A4K2S1 | 487 | STK4_LEMCA Serine/threonine-protein kinase 4 ... | 272 | 6e-38 | 154 | 32 | 54 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB. | 65 | O55098 | 966 | STK10_MOUSE Serine/threonine-protein kinase 1... | 281 | 8e-38 | 158 | 35 | 52 | GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; IMP:UniProtKB. | 66 | Q802A6 | 491 | STK4_SQUAC Serine/threonine-protein kinase 3/... | 268 | 9e-38 | 154 | 33 | 54 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB. | 67 | O14305 | 471 | SID1_SCHPO Serine/threonine-protein kinase si... | 280 | 1e-37 | 153 | 37 | 55 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase. | | | | | | | | | | GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0031028; P:septation initiation signaling cascade; IMP:PomBase. | 68 | Q13188 | 491 | STK3_HUMAN Serine/threonine-protein kinase 3 ... | 270 | 1e-37 | 154 | 33 | 55 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0046983; F:protein dimerization activity; ISS:UniProtKB.::GO:0043539; F:protein serine/threonine kinase activator activity; IDA:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:UniProtKB.::GO:0035329; P:hippo signaling cascade; TAS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB. | 69 | Q94A06 | 354 | M2K1_ARATH Mitogen-activated protein kinase k... | 278 | 1e-37 | 151 | 35 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042742; P:defense response to bacterium; IDA:TAIR.::GO:0009814; P:defense response, incompatible interaction; IGI:TAIR.::GO:0042542; P:response to hydrogen peroxide; IDA:TAIR.::GO:0002237; P:response to molecule of bacterial origin; IDA:TAIR.::GO:0009414; P:response to water deprivation; IMP:TAIR.::GO:0009611; P:response to wounding; IEP:TAIR. | 70 | A4K2Q5 | 487 | STK4_OTOGA Serine/threonine-protein kinase 4 ... | 272 | 1e-37 | 154 | 32 | 54 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB. | 71 | Q9NB31 | 497 | CST1_CAEEL Serine/threonine-protein kinase cs... | 268 | 1e-37 | 153 | 34 | 54 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008340; P:determination of adult lifespan; IMP:UniProtKB.::GO:0048747; P:muscle fiber development; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 72 | P35465 | 544 | PAK1_RAT Serine/threonine-protein kinase PAK ... | 291 | 1e-37 | 154 | 33 | 53 | GO:0030424; C:axon; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0030425; C:dendrite; IDA:RGD.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0014704; C:intercalated disc; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0031965; C:nuclear membrane; IDA:RGD.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB.::GO:0030018; C:Z disc; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005518; F:collagen binding; ISS:UniProtKB.::GO:0004709; F:MAP kinase kinase kinase activity; TAS:RGD.::GO:0019901; F:protein kinase binding; IPI:RGD. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0048754; P:branching morphogenesis of a tube; ISS:UniProtKB.::GO:0032869; P:cellular response to insulin stimulus; IDA:RGD.::GO:0033554; P:cellular response to stress; IDA:RGD.::GO:0060244; P:negative regulation of cell proliferation involved in contact inhibition; ISS:UniProtKB.::GO:0048812; P:neuron projection morphogenesis; IMP:RGD.::GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; ISS:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0051496; P:positive regulation of stress fiber assembly; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0001666; P:response to hypoxia; IDA:RGD.::GO:0007264; P:small GTPase mediated signal transduction; TAS:RGD.::GO:0042060; P:wound healing; ISS:UniProtKB. | 73 | Q08E52 | 544 | PAK1_BOVIN Serine/threonine-protein kinase PA... | 291 | 2e-37 | 154 | 33 | 53 | GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005518; F:collagen binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0048754; P:branching morphogenesis of a tube; ISS:UniProtKB.::GO:0060244; P:negative regulation of cell proliferation involved in contact inhibition; ISS:UniProtKB.::GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; ISS:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0051496; P:positive regulation of stress fiber assembly; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0042060; P:wound healing; ISS:UniProtKB. | 74 | Q13153 | 545 | PAK1_HUMAN Serine/threonine-protein kinase PA... | 291 | 2e-37 | 154 | 33 | 53 | GO:0030424; C:axon; ISS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0014704; C:intercalated disc; ISS:UniProtKB.::GO:0031965; C:nuclear membrane; ISS:UniProtKB.::GO:0043234; C:protein complex; IDA:UniProtKB.::GO:0001726; C:ruffle; IDA:UniProtKB.::GO:0030018; C:Z disc; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005518; F:collagen binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; IDA:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0048754; P:branching morphogenesis of a tube; IMP:UniProtKB.::GO:0060244; P:negative regulation of cell proliferation involved in contact inhibition; IMP:UniProtKB.::GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; IDA:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; IMP:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0051496; P:positive regulation of stress fiber assembly; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0042060; P:wound healing; IMP:UniProtKB. | 75 | Q0IHQ8 | 951 | STK10_XENTR Serine/threonine-protein kinase 1... | 275 | 2e-37 | 157 | 35 | 52 | GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB. | 76 | Q869T7 | 1176 | PAKF_DICDI Serine/threonine-protein kinase pa... | 311 | 2e-37 | 157 | 30 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase. | | | | | | | | | | | 77 | Q8K3H5 | 1613 | MYO3A_MOUSE Myosin-IIIa OS=Mus musculus (Mous... | 299 | 2e-37 | 157 | 35 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0031941; C:filamentous actin; ISS:UniProtKB.::GO:0030175; C:filopodium; ISS:UniProtKB.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0030898; F:actin-dependent ATPase activity; ISS:UniProtKB.::GO:0043531; F:ADP binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; ISS:UniProtKB.::GO:0060002; F:plus-end directed microfilament motor activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007605; P:sensory perception of sound; ISS:UniProtKB.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 78 | Q7ZUQ3 | 492 | STK3_DANRE Serine/threonine-protein kinase 3 ... | 269 | 2e-37 | 153 | 33 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB. | 79 | Q5ZJK4 | 486 | STK4_CHICK Serine/threonine-protein kinase 4 ... | 272 | 3e-37 | 152 | 32 | 54 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB. | 80 | O54748 | 491 | STK3_RAT Serine/threonine-protein kinase 3 OS... | 268 | 4e-37 | 152 | 33 | 54 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB. | 81 | Q64303 | 524 | PAK2_RAT Serine/threonine-protein kinase PAK ... | 291 | 5e-37 | 152 | 32 | 53 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 82 | Q8CIN4 | 524 | PAK2_MOUSE Serine/threonine-protein kinase PA... | 291 | 6e-37 | 152 | 32 | 53 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW. | 83 | Q29502 | 524 | PAK2_RABIT Serine/threonine-protein kinase PA... | 291 | 6e-37 | 152 | 32 | 53 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0097194; P:execution phase of apoptosis; IMP:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB. | 84 | Q99683 | 1374 | M3K5_HUMAN Mitogen-activated protein kinase k... | 272 | 7e-37 | 155 | 36 | 56 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0019903; F:protein phosphatase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.::GO:0070301; P:cellular response to hydrogen peroxide; IDA:BHF-UCL.::GO:0010421; P:hydrogen peroxide-mediated programmed cell death; IDA:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:ProtInc.::GO:0008631; P:induction of apoptosis by oxidative stress; IDA:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW. | 85 | Q9JI10 | 497 | STK3_MOUSE Serine/threonine-protein kinase 3 ... | 268 | 7e-37 | 151 | 33 | 54 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0046983; F:protein dimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0060706; P:cell differentiation involved in embryonic placenta development; IGI:MGI.::GO:0007417; P:central nervous system development; IGI:MGI.::GO:0003157; P:endocardium development; IGI:MGI.::GO:0035329; P:hippo signaling cascade; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IGI:MGI.::GO:0008285; P:negative regulation of cell proliferation; IGI:MGI.::GO:0046621; P:negative regulation of organ growth; IGI:MGI.::GO:0001841; P:neural tube formation; IGI:MGI.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0060215; P:primitive hemopoiesis; IGI:MGI. | 86 | Q62829 | 544 | PAK3_RAT Serine/threonine-protein kinase PAK ... | 269 | 7e-37 | 152 | 33 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051020; F:GTPase binding; IDA:RGD.::GO:0004708; F:MAP kinase kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007409; P:axonogenesis; ISS:UniProtKB.::GO:0016358; P:dendrite development; ISS:UniProtKB.::GO:0030833; P:regulation of actin filament polymerization; ISS:UniProtKB. | 87 | Q13177 | 524 | PAK2_HUMAN Serine/threonine-protein kinase PA... | 317 | 8e-37 | 151 | 31 | 51 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:BHF-UCL.::GO:0030296; F:protein tyrosine kinase activator activity; IDA:BHF-UCL. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:2001271; P:negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis; IDA:UniProtKB.::GO:0006469; P:negative regulation of protein kinase activity; TAS:ProtInc.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.::GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome. | 88 | O35099 | 1380 | M3K5_MOUSE Mitogen-activated protein kinase k... | 267 | 9e-37 | 155 | 36 | 55 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; IDA:MGI.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW. | 89 | A4K2W5 | 487 | STK4_AOTNA Serine/threonine-protein kinase 4 ... | 272 | 9e-37 | 150 | 32 | 53 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 90 | Q61036 | 559 | PAK3_MOUSE Serine/threonine-protein kinase PA... | 291 | 1e-36 | 151 | 32 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0017048; F:Rho GTPase binding; IPI:BHF-UCL.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007409; P:axonogenesis; IMP:UniProtKB.::GO:0016358; P:dendrite development; IMP:UniProtKB.::GO:0030833; P:regulation of actin filament polymerization; ISS:UniProtKB. | 91 | Q7YQL3 | 559 | PAK3_PONPY Serine/threonine-protein kinase PA... | 291 | 1e-36 | 151 | 32 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007409; P:axonogenesis; ISS:UniProtKB.::GO:0016358; P:dendrite development; ISS:UniProtKB.::GO:0030833; P:regulation of actin filament polymerization; ISS:UniProtKB. |
