| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
511 | Q9HC98 | 313 | NEK6_HUMAN Serine/threonine-protein kinase Ne... | 260 | 1e-24 | 111 | 28 | 50 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0019894; F:kinesin binding; IPI:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004871; F:signal transducer activity; IMP:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IDA:UniProtKB.::GO:0000910; P:cytokinesis; TAS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000772; P:regulation of cellular senescence; TAS:UniProtKB.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IDA:UniProtKB.::GO:0051225; P:spindle assembly; TAS:UniProtKB. | 512 | O09110 | 347 | MP2K3_MOUSE Dual specificity mitogen-activate... | 281 | 1e-24 | 111 | 29 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; IDA:MGI.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0060048; P:cardiac muscle contraction; IMP:MGI.::GO:0006954; P:inflammatory response; IMP:MGI.::GO:0042035; P:regulation of cytokine biosynthetic process; IMP:MGI. | 513 | P16912 | 583 | KDC2_DROME Protein kinase DC2 OS=Drosophila m... | 272 | 1e-24 | 114 | 29 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IDA:FlyBase.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase. | 514 | Q63531 | 735 | KS6A1_RAT Ribosomal protein S6 kinase alpha-1... | 234 | 0.0000000000001 | 79.7 | 29 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004711; F:ribosomal protein S6 kinase activity; TAS:RGD.::GO:0008134; F:transcription factor binding; IDA:RGD. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:2000491; P:positive regulation of hepatic stellate cell activation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:RGD. | 515 | Q8SRF5 | 265 | Y823_ENCCU Probable cell division protein kin... | 215 | 1e-24 | 110 | 32 | 52 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 516 | O01427 | 305 | AIR2_CAEEL Aurora/IPL1-related protein kinase... | 278 | 1e-24 | 111 | 25 | 45 | GO:0000794; C:condensed nuclear chromosome; IDA:WormBase.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0051233; C:spindle midzone; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051117; F:ATPase binding; IPI:WormBase.::GO:0019894; F:kinesin binding; IPI:WormBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:WormBase.::GO:0004713; F:protein tyrosine kinase activity; IDA:WormBase. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0030261; P:chromosome condensation; IMP:WormBase.::GO:0007059; P:chromosome segregation; IMP:WormBase.::GO:0007109; P:cytokinesis, completion of separation; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0045184; P:establishment of protein localization; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0007126; P:meiosis; IMP:WormBase.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:WormBase.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:WormBase.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:WormBase.::GO:0046777; P:protein autophosphorylation; IDA:WormBase.::GO:0031991; P:regulation of contractile ring contraction involved in cell cycle cytokinesis; IMP:WormBase.::GO:0051256; P:spindle midzone assembly involved in mitosis; IMP:WormBase. | 517 | P31938 | 393 | MP2K1_MOUSE Dual specificity mitogen-activate... | 311 | 1e-24 | 112 | 30 | 45 | GO:0005829; C:cytosol; TAS:UniProtKB.::GO:0005769; C:early endosome; TAS:UniProtKB.::GO:0005925; C:focal adhesion; TAS:UniProtKB.::GO:0005794; C:Golgi apparatus; TAS:UniProtKB.::GO:0005770; C:late endosome; TAS:UniProtKB.::GO:0005739; C:mitochondrion; TAS:UniProtKB.::GO:0005634; C:nucleus; TAS:UniProtKB.::GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; IMP:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.::GO:0004728; F:receptor signaling protein tyrosine phosphatase activity; IMP:MGI. | | | | | | | | | | GO:0048870; P:cell motility; IMP:MGI.::GO:0030216; P:keratinocyte differentiation; IMP:MGI.::GO:0060711; P:labyrinthine layer development; IMP:MGI.::GO:0060674; P:placenta blood vessel development; IMP:MGI.::GO:0045597; P:positive regulation of cell differentiation; IDA:MGI.::GO:2000641; P:regulation of early endosome to late endosome transport; TAS:UniProtKB.::GO:0090170; P:regulation of Golgi inheritance; TAS:UniProtKB.::GO:0032872; P:regulation of stress-activated MAPK cascade; TAS:UniProtKB. | 518 | Q8ICR0 | 509 | CDPK2_PLAF7 Calcium-dependent protein kinase ... | 273 | 1e-24 | 113 | 27 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004683; F:calmodulin-dependent protein kinase activity; TAS:GeneDB_Pfalciparum. | | | | | | | | | | | 519 | P54646 | 552 | AAPK2_HUMAN 5'-AMP-activated protein kinase c... | 296 | 1e-24 | 113 | 29 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0004679; F:AMP-activated protein kinase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0035174; F:histone serine kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0006853; P:carnitine shuttle; TAS:Reactome.::GO:0007050; P:cell cycle arrest; TAS:Reactome.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0055089; P:fatty acid homeostasis; ISS:UniProtKB.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0032007; P:negative regulation of TOR signaling cascade; ISS:UniProtKB.::GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; ISS:UniProtKB.::GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.::GO:0042304; P:regulation of fatty acid biosynthetic process; TAS:Reactome.::GO:0046320; P:regulation of fatty acid oxidation; TAS:Reactome.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 520 | P25341 | 720 | KIN82_YEAST Serine/threonine-protein kinase K... | 298 | 1e-24 | 114 | 28 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006869; P:lipid transport; IEA:UniProtKB-KW.::GO:0019236; P:response to pheromone; IGI:SGD. | 521 | Q10664 | 387 | MEK2_CAEEL Dual specificity mitogen-activated... | 294 | 2e-24 | 111 | 30 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; IDA:WormBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0001703; P:gastrulation with mouth forming first; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0007265; P:Ras protein signal transduction; IGI:WormBase.::GO:0040025; P:vulval development; IGI:WormBase. | 522 | O15865 | 513 | CDPK2_PLAFK Calcium-dependent protein kinase ... | 273 | 2e-24 | 113 | 28 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 523 | Q9ES70 | 313 | NEK6_MOUSE Serine/threonine-protein kinase Ne... | 236 | 2e-24 | 110 | 29 | 51 | GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; ISS:UniProtKB. | 524 | Q05006 | 294 | CDC22_MEDSA Cell division control protein 2 h... | 302 | 2e-24 | 110 | 29 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 525 | Q04759 | 706 | KPCT_HUMAN Protein kinase C theta type OS=Hom... | 256 | 2e-24 | 114 | 31 | 48 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.::GO:0006509; P:membrane protein ectodomain proteolysis; ISS:BHF-UCL.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:UniProtKB.::GO:0070233; P:negative regulation of T cell apoptotic process; IMP:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0032740; P:positive regulation of interleukin-17 production; ISS:UniProtKB.::GO:0032753; P:positive regulation of interleukin-4 production; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:2000318; P:positive regulation of T-helper 17 type immune response; ISS:UniProtKB.::GO:2000570; P:positive regulation of T-helper 2 cell activation; ISS:UniProtKB.::GO:0001558; P:regulation of cell growth; NAS:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. | 526 | Q6DE08 | 361 | AUKBA_XENLA Aurora kinase B-A OS=Xenopus laev... | 317 | 2e-24 | 111 | 27 | 44 | | | | | | | | | | | | | | | | | | | | | | 527 | Q9NRP7 | 1315 | STK36_HUMAN Serine/threonine-protein kinase 3... | 270 | 2e-24 | 115 | 31 | 50 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0000287; F:magnesium ion binding; IC:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB.::GO:0008134; F:transcription factor binding; IDA:UniProtKB. | | | | | | | | | | GO:0042384; P:cilium assembly; ISS:UniProtKB.::GO:0007228; P:positive regulation of hh target transcription factor activity; ISS:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0009791; P:post-embryonic development; ISS:UniProtKB. | 528 | Q91ZR4 | 698 | NEK8_MOUSE Serine/threonine-protein kinase Ne... | 251 | 2e-24 | 114 | 30 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0072372; C:primary cilium; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 529 | O14965 | 403 | AURKA_HUMAN Aurora kinase A OS=Homo sapiens (... | 272 | 2e-24 | 111 | 28 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0030496; C:midbody; TAS:UniProtKB.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.::GO:0005876; C:spindle microtubule; IDA:BHF-UCL.::GO:0031616; C:spindle pole centrosome; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; TAS:UniProtKB. | | | | | | | | | | GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; TAS:ProtInc.::GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:UniProtKB.::GO:0045840; P:positive regulation of mitosis; TAS:UniProtKB.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0046605; P:regulation of centrosome cycle; TAS:UniProtKB.::GO:0031647; P:regulation of protein stability; IMP:UniProtKB.::GO:0007051; P:spindle organization; NAS:UniProtKB. | 530 | Q28948 | 552 | AAPK2_PIG 5'-AMP-activated protein kinase cat... | 294 | 2e-24 | 113 | 29 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 531 | Q09137 | 552 | AAPK2_RAT 5'-AMP-activated protein kinase cat... | 296 | 2e-24 | 113 | 29 | 47 | GO:0031588; C:AMP-activated protein kinase complex; IDA:RGD.::GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0004679; F:AMP-activated protein kinase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IDA:RGD.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0035174; F:histone serine kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0030674; F:protein binding, bridging; IDA:RGD. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0071417; P:cellular response to organic nitrogen; IEP:RGD.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0055089; P:fatty acid homeostasis; IDA:UniProtKB.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0032007; P:negative regulation of TOR signaling cascade; ISS:UniProtKB.::GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; IDA:UniProtKB.::GO:0051291; P:protein heterooligomerization; IDA:RGD.::GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; IDA:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; IDA:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0014823; P:response to activity; IDA:RGD.::GO:0031000; P:response to caffeine; IDA:RGD.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 532 | Q4R8T9 | 590 | CDKL3_MACFA Cyclin-dependent kinase-like 3 OS... | 295 | 2e-24 | 113 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 533 | Q63450 | 374 | KCC1A_RAT Calcium/calmodulin-dependent protei... | 290 | 2e-24 | 111 | 30 | 49 | GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0060999; P:positive regulation of dendritic spine development; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0071902; P:positive regulation of protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0051835; P:positive regulation of synapse structural plasticity; ISS:UniProtKB.::GO:0051147; P:regulation of muscle cell differentiation; ISS:UniProtKB.::GO:0043393; P:regulation of protein binding; ISS:UniProtKB.::GO:0032880; P:regulation of protein localization; ISS:UniProtKB. | 534 | Q7Z2Y5 | 1582 | NRK_HUMAN Nik-related protein kinase OS=Homo ... | 304 | 2e-24 | 115 | 30 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | | 535 | Q91YS8 | 374 | KCC1A_MOUSE Calcium/calmodulin-dependent prot... | 290 | 2e-24 | 111 | 30 | 49 | GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006913; P:nucleocytoplasmic transport; IDA:MGI.::GO:0060999; P:positive regulation of dendritic spine development; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0046827; P:positive regulation of protein export from nucleus; IDA:MGI.::GO:0071902; P:positive regulation of protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0051835; P:positive regulation of synapse structural plasticity; ISS:UniProtKB.::GO:0043393; P:regulation of protein binding; ISS:UniProtKB.::GO:0007165; P:signal transduction; IDA:MGI. | 536 | P52564 | 334 | MP2K6_HUMAN Dual specificity mitogen-activate... | 281 | 2e-24 | 110 | 28 | 48 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; TAS:ProtInc.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007050; P:cell cycle arrest; TAS:ProtInc.::GO:0006975; P:DNA damage induced protein phosphorylation; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0042692; P:muscle cell differentiation; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.::GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 537 | P18652 | 752 | KS6AA_CHICK Ribosomal protein S6 kinase 2 alp... | 222 | 0.000000000002 | 75.9 | 28 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro. | 538 | Q5R4L1 | 685 | PLK2_PONAB Serine/threonine-protein kinase PL... | 313 | 2e-24 | 114 | 27 | 45 | GO:0005814; C:centriole; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0060292; P:long term synaptic depression; ISS:UniProtKB.::GO:0060291; P:long-term synaptic potentiation; ISS:UniProtKB.::GO:0007613; P:memory; ISS:UniProtKB.::GO:0007093; P:mitotic cell cycle checkpoint; ISS:UniProtKB.::GO:0007052; P:mitotic spindle organization; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.::GO:0046599; P:regulation of centriole replication; ISS:UniProtKB. | 539 | Q8IVW4 | 592 | CDKL3_HUMAN Cyclin-dependent kinase-like 3 OS... | 295 | 2e-24 | 113 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 540 | Q9NYY3 | 685 | PLK2_HUMAN Serine/threonine-protein kinase PL... | 313 | 3e-24 | 114 | 27 | 45 | GO:0005814; C:centriole; IDA:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004871; F:signal transducer activity; IMP:UniProtKB. | | | | | | | | | | GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:UniProtKB.::GO:0060292; P:long term synaptic depression; ISS:UniProtKB.::GO:0060291; P:long-term synaptic potentiation; ISS:UniProtKB.::GO:0007613; P:memory; ISS:UniProtKB.::GO:0007093; P:mitotic cell cycle checkpoint; ISS:UniProtKB.::GO:0007052; P:mitotic spindle organization; IDA:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.::GO:0046599; P:regulation of centriole replication; IDA:UniProtKB. | 541 | P23573 | 314 | CDC2C_DROME Cell division control protein 2 c... | 248 | 3e-24 | 110 | 31 | 52 | GO:0005875; C:microtubule associated complex; IDA:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:FlyBase.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:FlyBase.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:FlyBase.::GO:0007259; P:JAK-STAT cascade; IPI:FlyBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. |
