rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P80667 | 386 | PEX13_YEAST Peroxisomal membrane protein PAS2... | 251 | 3e-57 | 199 | 43 | 60 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IDA:SGD. | | | | | | | | | | | | | | | | | | | | GO:0016560; P:protein import into peroxisome matrix, docking; IGI:SGD. | 2 | Q92266 | 380 | PEX13_PICPA Peroxisomal membrane protein PEX1... | 239 | 7e-43 | 160 | 38 | 60 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0016560; P:protein import into peroxisome matrix, docking; IEA:InterPro. | 3 | O14136 | 288 | PEX13_SCHPO Peroxisomal membrane protein pex1... | 235 | 3e-33 | 131 | 30 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; ISS:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0016560; P:protein import into peroxisome matrix, docking; IEA:InterPro. | 4 | Q92968 | 403 | PEX13_HUMAN Peroxisomal membrane protein PEX1... | 330 | 0.00000000002 | 68.9 | 23 | 41 | GO:0005779; C:integral to peroxisomal membrane; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0021795; P:cerebral cortex cell migration; ISS:UniProtKB.::GO:0001561; P:fatty acid alpha-oxidation; ISS:UniProtKB.::GO:0007626; P:locomotory behavior; ISS:UniProtKB.::GO:0060152; P:microtubule-based peroxisome localization; ISS:UniProtKB.::GO:0001764; P:neuron migration; ISS:UniProtKB.::GO:0016560; P:protein import into peroxisome matrix, docking; IMP:UniProtKB.::GO:0001967; P:suckling behavior; ISS:UniProtKB. | 5 | Q0P5B1 | 403 | PEX13_BOVIN Peroxisomal membrane protein PEX1... | 303 | 0.000000001 | 63.5 | 23 | 40 | GO:0005779; C:integral to peroxisomal membrane; ISS:UniProtKB.::GO:0005624; C:membrane fraction; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0016560; P:protein import into peroxisome matrix, docking; ISS:UniProtKB. | 6 | Q9D0K1 | 405 | PEX13_MOUSE Peroxisomal membrane protein PEX1... | 281 | 0.000000007 | 60.8 | 23 | 41 | | | | | | | | | | | GO:0000268; F:peroxisome targeting sequence binding; TAS:MGI. | | | | | | | | | | GO:0021795; P:cerebral cortex cell migration; IMP:MGI.::GO:0001561; P:fatty acid alpha-oxidation; IMP:MGI.::GO:0007626; P:locomotory behavior; IMP:MGI.::GO:0060152; P:microtubule-based peroxisome localization; IMP:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0016560; P:protein import into peroxisome matrix, docking; IMP:MGI.::GO:0001967; P:suckling behavior; IMP:MGI. | 7 | P47941 | 303 | CRKL_MOUSE Crk-like protein OS=Mus musculus (... | 146 | 0.0000004 | 55.1 | 28 | 44 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0009952; P:anterior/posterior pattern specification; IGI:MGI.::GO:0001568; P:blood vessel development; IGI:MGI.::GO:0007507; P:heart development; IGI:MGI.::GO:0009887; P:organ morphogenesis; IMP:MGI.::GO:0060017; P:parathyroid gland development; IGI:MGI.::GO:0048538; P:thymus development; IGI:MGI. | 8 | Q5U2U2 | 303 | CRKL_RAT Crk-like protein OS=Rattus norvegicu... | 136 | 0.0000005 | 54.7 | 28 | 43 | | | | | | | | | | | | | | | | | | | | | | 9 | Q19951 | 330 | PEX13_CAEEL Probable peroxisomal membrane pro... | 231 | 0.0000007 | 54.3 | 24 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0016560; P:protein import into peroxisome matrix, docking; IEA:InterPro. | 10 | P46109 | 303 | CRKL_HUMAN Crk-like protein OS=Homo sapiens (... | 146 | 0.000001 | 53.9 | 28 | 43 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.::GO:0004871; F:signal transducer activity; TAS:ProtInc. | | | | | | | | | | GO:0007254; P:JNK cascade; TAS:ProtInc.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc. | 11 | P53281 | 241 | LSB1_YEAST LAS seventeen-binding protein 1 OS... | 99 | 0.00005 | 48.1 | 32 | 51 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 12 | P43603 | 459 | LSB3_YEAST LAS seventeen-binding protein 3 OS... | 104 | 0.002 | 43.9 | 28 | 47 | GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0051666; P:actin cortical patch localization; IMP:SGD. | 13 | A7A261 | 459 | LSB3_YEAS7 LAS seventeen-binding protein 3 OS... | 104 | 0.002 | 43.9 | 28 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 14 | A6QLK6 | 217 | GRAP_BOVIN GRB2-related adapter protein OS=Bo... | 95 | 0.004 | 42.4 | 27 | 51 | | | | | | | | | | | | | | | | | | | | | | 15 | Q09014 | 390 | NCF1_MOUSE Neutrophil cytosol factor 1 OS=Mus... | 107 | 0.008 | 42 | 30 | 48 | GO:0005829; C:cytosol; TAS:MGI. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:MGI.::GO:0016175; F:superoxide-generating NADPH oxidase activity; IDA:MGI. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0008283; P:cell proliferation; IMP:MGI.::GO:0006968; P:cellular defense response; IMP:MGI.::GO:0050665; P:hydrogen peroxide biosynthetic process; IMP:MGI.::GO:0006954; P:inflammatory response; IMP:MGI.::GO:0006691; P:leukotriene metabolic process; IMP:MGI.::GO:0045986; P:negative regulation of smooth muscle contraction; IMP:MGI.::GO:0070947; P:neutrophil mediated killing of fungus; IMP:MGI.::GO:0070946; P:neutrophil mediated killing of gram-positive bacterium; IMP:MGI.::GO:0006612; P:protein targeting to membrane; ISS:UniProtKB.::GO:0002679; P:respiratory burst involved in defense response; IMP:MGI.::GO:0001878; P:response to yeast; IMP:MGI.::GO:0042554; P:superoxide anion generation; IMP:MGI. | 16 | Q99M51 | 377 | NCK1_MOUSE Cytoplasmic protein NCK1 OS=Mus mu... | 65 | 1.3 | 35 | 28 | 48 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0012506; C:vesicle membrane; IDA:MGI. | | | | | | | | | | GO:0019904; F:protein domain specific binding; IPI:MGI. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:MGI.::GO:0016477; P:cell migration; IMP:MGI.::GO:0030032; P:lamellipodium assembly; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. | 17 | P16333 | 377 | NCK1_HUMAN Cytoplasmic protein NCK1 OS=Homo s... | 65 | 1.4 | 34.7 | 28 | 48 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; NAS:UniProtKB.::GO:0005102; F:receptor binding; IPI:UniProtKB.::GO:0030159; F:receptor signaling complex scaffold activity; NAS:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:UniProtKB.::GO:0042102; P:positive regulation of T cell proliferation; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0007172; P:signal complex assembly; NAS:UniProtKB.::GO:0042110; P:T cell activation; IMP:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. | 18 | Q06449 | 215 | PIN3_YEAST [PSI+] inducibility protein 3 OS=S... | 99 | 0.012 | 40.8 | 32 | 44 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IPI:SGD. | 19 | Q5BBL4 | 581 | HSE1_EMENI Class E vacuolar protein-sorting m... | 69 | 0.018 | 41.2 | 33 | 51 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 20 | P87378 | 296 | CRK_XENLA Adapter molecule crk OS=Xenopus lae... | 70 | 0.031 | 39.7 | 29 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 21 | P42682 | 527 | TXK_MOUSE Tyrosine-protein kinase TXK OS=Mus ... | 62 | 0.032 | 40 | 32 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; IMP:UniProtKB.::GO:0002250; P:adaptive immune response; IMP:UniProtKB.::GO:0032609; P:interferon-gamma production; IGI:MGI.::GO:0032633; P:interleukin-4 production; IGI:MGI.::GO:0001865; P:NK T cell differentiation; IGI:MGI.::GO:0050852; P:T cell receptor signaling pathway; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 22 | Q8JH64 | 657 | BTK_CHICK Tyrosine-protein kinase BTK OS=Gall... | 51 | 0.033 | 40.4 | 39 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 23 | Q06187 | 659 | BTK_HUMAN Tyrosine-protein kinase BTK OS=Homo... | 77 | 0.046 | 39.7 | 29 | 52 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0045121; C:membrane raft; IDA:HGNC.::GO:0005634; C:nucleus; TAS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; TAS:HGNC.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB. | | | | | | | | | | GO:0002250; P:adaptive immune response; TAS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042113; P:B cell activation; TAS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; TAS:UniProtKB.::GO:0019722; P:calcium-mediated signaling; TAS:HGNC.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:UniProtKB.::GO:0007498; P:mesoderm development; TAS:ProtInc.::GO:0045579; P:positive regulation of B cell differentiation; TAS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:UniProtKB.::GO:0002902; P:regulation of B cell apoptotic process; TAS:UniProtKB.::GO:0002721; P:regulation of B cell cytokine production; TAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 24 | Q4WHP5 | 584 | HSE1_ASPFU Class E vacuolar protein-sorting m... | 69 | 0.046 | 39.7 | 32 | 51 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 25 | A1DFN5 | 603 | HSE1_NEOFI Class E vacuolar protein-sorting m... | 69 | 0.051 | 39.7 | 32 | 51 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 26 | A1CEK6 | 599 | HSE1_ASPCL Class E vacuolar protein-sorting m... | 69 | 0.051 | 39.7 | 32 | 51 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 27 | Q04929 | 305 | CRK_CHICK Adapter molecule crk OS=Gallus gall... | 85 | 0.053 | 39.3 | 25 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB. | 28 | P42690 | 506 | SRK4_SPOLA Tyrosine-protein kinase isoform SR... | 45 | 0.058 | 39.3 | 40 | 64 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 29 | A2QW93 | 611 | HSE1_ASPNC Class E vacuolar protein-sorting m... | 69 | 0.062 | 39.3 | 32 | 51 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 30 | P42686 | 505 | SRK1_SPOLA Tyrosine-protein kinase isoform SR... | 45 | 0.064 | 39.3 | 40 | 64 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 31 | Q0CJU8 | 597 | HSE1_ASPTN Class E vacuolar protein-sorting m... | 69 | 0.064 | 39.3 | 32 | 51 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. |