rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q08BS4 | 760 | EZH2_DANRE Histone-lysine N-methyltransferase... | 263 | 4e-36 | 151 | 38 | 49 | GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 2 | P70351 | 747 | EZH1_MOUSE Histone-lysine N-methyltransferase... | 263 | 1e-35 | 149 | 39 | 48 | GO:0035098; C:ESC/E(Z) complex; IDA:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0046976; F:histone methyltransferase activity (H3-K27 specific); IDA:MGI.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 3 | A7E2Z2 | 747 | EZH1_BOVIN Histone-lysine N-methyltransferase... | 263 | 1e-35 | 149 | 39 | 49 | GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 4 | Q92800 | 747 | EZH1_HUMAN Histone-lysine N-methyltransferase... | 263 | 2e-35 | 149 | 38 | 48 | GO:0035098; C:ESC/E(Z) complex; IDA:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; TAS:ProtInc.::GO:0003677; F:DNA binding; IEA:InterPro. | | | | | | | | | | GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 5 | Q98SM3 | 748 | EZH2A_XENLA Histone-lysine N-methyltransferas... | 322 | 2e-35 | 149 | 34 | 47 | GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 6 | Q28D84 | 748 | EZH2_XENTR Histone-lysine N-methyltransferase... | 322 | 4e-35 | 148 | 34 | 47 | GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 7 | Q61188 | 746 | EZH2_MOUSE Histone-lysine N-methyltransferase... | 263 | 4e-35 | 148 | 38 | 49 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0035098; C:ESC/E(Z) complex; IDA:UniProtKB.::GO:0045120; C:pronucleus; IDA:MGI. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0001047; F:core promoter binding; IDA:MGI.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI. | | | | | | | | | | GO:0021695; P:cerebellar cortex development; IMP:MGI.::GO:0070314; P:G1 to G0 transition; IMP:MGI.::GO:0070734; P:histone H3-K27 methylation; IMP:MGI.::GO:0045605; P:negative regulation of epidermal cell differentiation; IMP:MGI.::GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; ISS:UniProtKB.::GO:0051154; P:negative regulation of striated muscle cell differentiation; IDA:MGI.::GO:0034244; P:negative regulation of transcription elongation from RNA polymerase II promoter; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; IMP:MGI.::GO:0014013; P:regulation of gliogenesis; IMP:MGI.::GO:0001932; P:regulation of protein phosphorylation; IMP:MGI.::GO:0000084; P:S phase of mitotic cell cycle; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 8 | Q4R381 | 746 | EZH2_MACFA Histone-lysine N-methyltransferase... | 263 | 4e-35 | 148 | 38 | 49 | GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 9 | Q15910 | 746 | EZH2_HUMAN Histone-lysine N-methyltransferase... | 263 | 4e-35 | 148 | 38 | 49 | GO:0035098; C:ESC/E(Z) complex; IDA:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 10 | Q5RDS6 | 747 | EZH1_PONAB Histone-lysine N-methyltransferase... | 263 | 9e-35 | 147 | 38 | 48 | GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 11 | Q4V863 | 748 | EZH2B_XENLA Histone-lysine N-methyltransferas... | 322 | 3e-34 | 145 | 33 | 47 | GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 12 | P42124 | 760 | EZ_DROME Histone-lysine N-methyltransferase E... | 263 | 6e-33 | 141 | 37 | 49 | GO:0035098; C:ESC/E(Z) complex; IDA:FlyBase.::GO:0000790; C:nuclear chromatin; NAS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; NAS:UniProtKB.::GO:0046976; F:histone methyltransferase activity (H3-K27 specific); IDA:FlyBase.::GO:0046974; F:histone methyltransferase activity (H3-K9 specific); IDA:FlyBase.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0006723; P:cuticle hydrocarbon biosynthetic process; IMP:FlyBase.::GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0016458; P:gene silencing; NAS:UniProtKB.::GO:0007517; P:muscle organ development; IMP:FlyBase.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0035186; P:syncytial blastoderm mitotic cell cycle; IMP:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 13 | Q8S4P6 | 931 | EZ1_MAIZE Histone-lysine N-methyltransferase ... | 299 | 5e-27 | 123 | 32 | 44 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 14 | O65312 | 689 | MEDEA_ARATH Histone-lysine N-methyltransferas... | 239 | 1e-25 | 118 | 36 | 49 | GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0043565; F:sequence-specific DNA binding; IDA:TAIR. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:TAIR.::GO:2000014; P:regulation of endosperm development; IMP:TAIR.::GO:0006349; P:regulation of gene expression by genetic imprinting; IMP:TAIR.::GO:0009646; P:response to absence of light; IEP:TAIR.::GO:0048317; P:seed morphogenesis; IGI:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 15 | P93831 | 902 | CLF_ARATH Histone-lysine N-methyltransferase ... | 282 | 3e-25 | 117 | 33 | 45 | GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003727; F:single-stranded RNA binding; IDA:TAIR. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009294; P:DNA mediated transformation; IMP:TAIR.::GO:0009908; P:flower development; IEA:UniProtKB-KW.::GO:0009965; P:leaf morphogenesis; IMP:TAIR.::GO:0045857; P:negative regulation of molecular function, epigenetic; IMP:TAIR.::GO:0006349; P:regulation of gene expression by genetic imprinting; IMP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0010228; P:vegetative to reproductive phase transition of meristem; IMP:TAIR. | 16 | Q8S4P5 | 894 | EZ2_MAIZE Histone-lysine N-methyltransferase ... | 247 | 2e-23 | 111 | 34 | 48 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 17 | Q8S4P4 | 895 | EZ3_MAIZE Histone-lysine N-methyltransferase ... | 263 | 3e-23 | 110 | 32 | 48 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 18 | O17514 | 773 | MES2_CAEEL Histone-lysine N-methyltransferase... | 304 | 2e-22 | 107 | 30 | 44 | GO:0000786; C:nucleosome; IDA:WormBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0042078; P:germ-line stem cell division; IMP:WormBase.::GO:0070734; P:histone H3-K27 methylation; IMP:WormBase.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:WormBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 19 | Q9ZSM8 | 856 | EZA1_ARATH Histone-lysine N-methyltransferase... | 240 | 8e-21 | 102 | 33 | 48 | GO:0005634; C:nucleus; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0003727; F:single-stranded RNA binding; IDA:TAIR. | | | | | | | | | | GO:0009960; P:endosperm development; IGI:TAIR.::GO:0006349; P:regulation of gene expression by genetic imprinting; IMP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 20 | Q32PH7 | 410 | SUV92_BOVIN Histone-lysine N-methyltransferas... | 144 | 3e-16 | 85.9 | 40 | 56 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 21 | Q9EQQ0 | 477 | SUV92_MOUSE Histone-lysine N-methyltransferas... | 144 | 6e-16 | 85.9 | 39 | 56 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005720; C:nuclear heterochromatin; IDA:MGI. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0046974; F:histone methyltransferase activity (H3-K9 specific); ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006333; P:chromatin assembly or disassembly; ISS:UniProtKB.::GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0007140; P:male meiosis; IEP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 22 | Q2NL30 | 412 | SUV91_BOVIN Histone-lysine N-methyltransferas... | 142 | 0.000000000000004 | 82.8 | 38 | 58 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0000792; C:heterochromatin; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0046974; F:histone methyltransferase activity (H3-K9 specific); ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 23 | Q5F3W5 | 407 | SUV92_CHICK Histone-lysine N-methyltransferas... | 144 | 0.000000000000004 | 82.4 | 39 | 55 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 24 | Q5RB81 | 412 | SUV91_PONAB Histone-lysine N-methyltransferas... | 142 | 0.000000000000004 | 82.4 | 38 | 58 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0000792; C:heterochromatin; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0046974; F:histone methyltransferase activity (H3-K9 specific); ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 25 | O43463 | 412 | SUV91_HUMAN Histone-lysine N-methyltransferas... | 142 | 0.000000000000004 | 82.4 | 38 | 58 | GO:0005677; C:chromatin silencing complex; IDA:UniProtKB.::GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0000794; C:condensed nuclear chromosome; TAS:ProtInc.::GO:0033553; C:rDNA heterochromatin; IDA:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; TAS:ProtInc.::GO:0046974; F:histone methyltransferase activity (H3-K9 specific); IDA:UniProtKB.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0000183; P:chromatin silencing at rDNA; IDA:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 26 | O54864 | 412 | SUV91_MOUSE Histone-lysine N-methyltransferas... | 142 | 0.00000000000001 | 81.6 | 38 | 57 | GO:0005677; C:chromatin silencing complex; IDA:UniProtKB.::GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005720; C:nuclear heterochromatin; TAS:MGI. | | | | | | | | | | GO:0046974; F:histone methyltransferase activity (H3-K9 specific); IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006323; P:DNA packaging; TAS:MGI.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 27 | Q6DGD3 | 411 | SV91A_DANRE Histone-lysine N-methyltransferas... | 142 | 0.00000000000001 | 81.3 | 39 | 58 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0031017; P:exocrine pancreas development; IMP:ZFIN.::GO:0051567; P:histone H3-K9 methylation; IMP:ZFIN.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0060042; P:retina morphogenesis in camera-type eye; IMP:ZFIN.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 28 | Q4R3E0 | 410 | SUV92_MACFA Histone-lysine N-methyltransferas... | 144 | 0.00000000000002 | 80.5 | 39 | 54 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 29 | Q9H5I1 | 410 | SUV92_HUMAN Histone-lysine N-methyltransferas... | 144 | 0.00000000000002 | 80.5 | 39 | 54 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046974; F:histone methyltransferase activity (H3-K9 specific); IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006333; P:chromatin assembly or disassembly; IMP:UniProtKB.::GO:0006338; P:chromatin remodeling; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 30 | O88491 | 2588 | NSD1_MOUSE Histone-lysine N-methyltransferase... | 116 | 0.00000000000002 | 82.4 | 41 | 53 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0035097; C:histone methyltransferase complex; IC:UniProtKB. | | | | | | | | | | GO:0050681; F:androgen receptor binding; ISS:UniProtKB.::GO:0030331; F:estrogen receptor binding; IPI:UniProtKB.::GO:0046975; F:histone methyltransferase activity (H3-K36 specific); IDA:UniProtKB.::GO:0042799; F:histone methyltransferase activity (H4-K20 specific); IDA:UniProtKB.::GO:0016922; F:ligand-dependent nuclear receptor binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0046965; F:retinoid X receptor binding; IPI:UniProtKB.::GO:0046966; F:thyroid hormone receptor binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 31 | Q96L73 | 2696 | NSD1_HUMAN Histone-lysine N-methyltransferase... | 116 | 0.00000000000002 | 82.4 | 41 | 53 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050681; F:androgen receptor binding; IDA:UniProtKB.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0030331; F:estrogen receptor binding; ISS:UniProtKB.::GO:0046975; F:histone methyltransferase activity (H3-K36 specific); IDA:UniProtKB.::GO:0042799; F:histone methyltransferase activity (H4-K20 specific); ISS:UniProtKB.::GO:0016922; F:ligand-dependent nuclear receptor binding; ISS:UniProtKB.::GO:0046965; F:retinoid X receptor binding; ISS:UniProtKB.::GO:0046966; F:thyroid hormone receptor binding; ISS:UniProtKB.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |