rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | Q9BZ95 | 1437 | NSD3_HUMAN Histone-lysine N-methyltransferase... | 116 | 0.00000000002 | 72.8 | 40 | 52 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IC:UniProtKB. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; NAS:UniProtKB.::GO:0016049; P:cell growth; NAS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 62 | Q6CIT4 | 1000 | SET1_KLULA Histone-lysine N-methyltransferase... | 129 | 0.00000000002 | 72.4 | 39 | 51 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0048188; C:Set1C/COMPASS complex; IEA:InterPro. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | | 63 | Q99MY8 | 2958 | ASH1L_MOUSE Histone-lysine N-methyltransferas... | 193 | 0.00000000002 | 72.8 | 30 | 48 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 64 | P0CO26 | 1469 | SET1_CRYNJ Histone-lysine N-methyltransferase... | 134 | 0.00000000002 | 72.8 | 36 | 51 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 65 | P0CO27 | 1469 | SET1_CRYNB Histone-lysine N-methyltransferase... | 134 | 0.00000000002 | 72.8 | 36 | 51 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 66 | Q4WTT2 | 966 | SET2_ASPFU Histone-lysine N-methyltransferase... | 143 | 0.00000000002 | 72 | 38 | 51 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 67 | Q9NR48 | 2969 | ASH1L_HUMAN Histone-lysine N-methyltransferas... | 190 | 0.00000000003 | 72.4 | 29 | 48 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005923; C:tight junction; TAS:ProtInc. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0006323; P:DNA packaging; TAS:ProtInc.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc. | 68 | P55200 | 3966 | MLL1_MOUSE Histone-lysine N-methyltransferase... | 121 | 0.00000000003 | 72.4 | 34 | 54 | GO:0071339; C:MLL1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0070577; F:histone acetyl-lysine binding; ISS:UniProtKB.::GO:0042800; F:histone methyltransferase activity (H3-K4 specific); ISS:UniProtKB.::GO:0045322; F:unmethylated CpG binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0009952; P:anterior/posterior pattern specification; IMP:MGI.::GO:0006306; P:DNA methylation; IMP:MGI.::GO:0035162; P:embryonic hemopoiesis; IMP:MGI.::GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0051569; P:regulation of histone H3-K4 methylation; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 69 | Q6FKB1 | 1111 | SET1_CANGA Histone-lysine N-methyltransferase... | 129 | 0.00000000003 | 72 | 38 | 50 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0048188; C:Set1C/COMPASS complex; IEA:InterPro. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | | 70 | Q7RZU4 | 954 | SET2_NEUCR Histone-lysine N-methyltransferase... | 207 | 0.00000000003 | 71.6 | 30 | 43 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 71 | Q03164 | 3969 | MLL1_HUMAN Histone-lysine N-methyltransferase... | 121 | 0.00000000004 | 72 | 34 | 54 | GO:0071339; C:MLL1 complex; IDA:UniProtKB. | | | | | | | | | | GO:0003680; F:AT DNA binding; NAS:UniProtKB.::GO:0070577; F:histone acetyl-lysine binding; IDA:UniProtKB.::GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.::GO:0045322; F:unmethylated CpG binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035162; P:embryonic hemopoiesis; TAS:UniProtKB.::GO:0080182; P:histone H3-K4 trimethylation; IDA:BHF-UCL.::GO:0043984; P:histone H4-K16 acetylation; IMP:UniProtKB.::GO:2001040; P:positive regulation of cellular response to drug; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0032411; P:positive regulation of transporter activity; IMP:BHF-UCL.::GO:0006461; P:protein complex assembly; IDA:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc. | 72 | Q2H988 | 894 | SET2_CHAGB Histone-lysine N-methyltransferase... | 144 | 0.00000000004 | 71.6 | 36 | 50 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 73 | P46995 | 733 | SET2_YEAST Histone-lysine N-methyltransferase... | 249 | 0.00000000004 | 71.2 | 26 | 42 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IPI:SGD. | | | | | | | | | | GO:0046975; F:histone methyltransferase activity (H3-K36 specific); IMP:SGD. | | | | | | | | | | GO:0030437; P:ascospore formation; IMP:SGD.::GO:0016575; P:histone deacetylation; IMP:SGD.::GO:0060195; P:negative regulation of antisense RNA transcription; IMP:SGD.::GO:0071441; P:negative regulation of histone H3-K14 acetylation; IMP:SGD.::GO:2000616; P:negative regulation of histone H3-K9 acetylation; IMP:SGD.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IMP:SGD.::GO:0035066; P:positive regulation of histone acetylation; IGI:SGD.::GO:0030174; P:regulation of DNA-dependent DNA replication initiation; IMP:SGD.::GO:0006354; P:transcription elongation, DNA-dependent; IDA:SGD. | 74 | Q2UMH3 | 1229 | SET1_ASPOR Histone-lysine N-methyltransferase... | 129 | 0.00000000004 | 71.6 | 34 | 53 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0048188; C:Set1C/COMPASS complex; IEA:InterPro. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 75 | Q4WNH8 | 1241 | SET1_ASPFU Histone-lysine N-methyltransferase... | 129 | 0.00000000006 | 70.9 | 34 | 53 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0048188; C:Set1C/COMPASS complex; IEA:InterPro. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 76 | Q9Y7R4 | 920 | SET1_SCHPO Histone-lysine N-methyltransferase... | 136 | 0.0000000001 | 70.1 | 38 | 52 | GO:0005737; C:cytoplasm; IDA:PomBase.::GO:0000790; C:nuclear chromatin; NAS:PomBase.::GO:0048188; C:Set1C/COMPASS complex; IDA:PomBase. | | | | | | | | | | GO:0042800; F:histone methyltransferase activity (H3-K4 specific); TAS:PomBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006338; P:chromatin remodeling; ISS:PomBase.::GO:0000077; P:DNA damage checkpoint; IGI:PomBase.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0000723; P:telomere maintenance; IMP:PomBase. | 77 | Q5ASA5 | 980 | SET2_EMENI Histone-lysine N-methyltransferase... | 143 | 0.0000000001 | 69.7 | 39 | 50 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 78 | Q54HS3 | 1486 | SET1_DICDI Histone-lysine N-methyltransferase... | 123 | 0.0000000002 | 69.3 | 34 | 54 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IC:dictyBase. | | | | | | | | | | GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IMP:dictyBase.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0040029; P:regulation of gene expression, epigenetic; IMP:dictyBase. | 79 | Q6FX50 | 716 | SET2_CANGA Histone-lysine N-methyltransferase... | 209 | 0.0000000004 | 67.8 | 29 | 44 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 80 | O08550 | 2713 | MLL4_MOUSE Histone-lysine N-methyltransferase... | 121 | 0.0000000007 | 67.8 | 36 | 52 | GO:0035097; C:histone methyltransferase complex; IDA:MGI. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016458; P:gene silencing; IMP:MGI.::GO:0080182; P:histone H3-K4 trimethylation; IMP:MGI.::GO:0009994; P:oocyte differentiation; IMP:MGI.::GO:0001541; P:ovarian follicle development; IMP:MGI.::GO:0030728; P:ovulation; IMP:MGI.::GO:0051569; P:regulation of histone H3-K4 methylation; IMP:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 81 | Q294B9 | 633 | SUV39_DROPS Histone-lysine N-methyltransferas... | 208 | 0.0000000007 | 67 | 30 | 44 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030702; P:chromatin silencing at centromere; ISS:UniProtKB.::GO:0006348; P:chromatin silencing at telomere; ISS:UniProtKB.::GO:0051567; P:histone H3-K9 methylation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 82 | Q9UMN6 | 2715 | MLL4_HUMAN Histone-lysine N-methyltransferase... | 121 | 0.0000000008 | 67.4 | 36 | 52 | | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; NAS:UniProtKB. | | | | | | | | | | GO:0048096; P:chromatin-mediated maintenance of transcription; NAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 83 | Q4IB50 | 1051 | SET2_GIBZE Histone-lysine N-methyltransferase... | 144 | 0.0000000008 | 67 | 34 | 49 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 84 | Q6BM04 | 731 | SET2_DEBHA Histone-lysine N-methyltransferase... | 144 | 0.000000001 | 66.2 | 32 | 53 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 85 | Q6CXP5 | 702 | SET2_KLULA Histone-lysine N-methyltransferase... | 146 | 0.000000001 | 66.2 | 32 | 51 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 86 | Q4I5R3 | 1252 | SET1_GIBZE Histone-lysine N-methyltransferase... | 129 | 0.000000002 | 65.9 | 34 | 47 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0048188; C:Set1C/COMPASS complex; IEA:InterPro. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 87 | Q9SUE7 | 1027 | ATX4_ARATH Histone-lysine N-methyltransferase... | 157 | 0.000000003 | 65.5 | 33 | 50 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 88 | Q8GZ42 | 1043 | ATX5_ARATH Histone-lysine N-methyltransferase... | 157 | 0.000000004 | 65.1 | 33 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0009506; C:plasmodesma; IDA:TAIR. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009294; P:DNA mediated transformation; IMP:TAIR. | 89 | O64827 | 1382 | SUVR5_ARATH Histone-lysine N-methyltransferas... | 147 | 0.000000004 | 65.1 | 30 | 54 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 90 | Q8NEZ4 | 4911 | MLL3_HUMAN Histone-lysine N-methyltransferase... | 120 | 0.000000006 | 64.7 | 29 | 55 | | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 91 | Q8BRH4 | 4903 | MLL3_MOUSE Histone-lysine N-methyltransferase... | 120 | 0.000000007 | 64.3 | 29 | 55 | GO:0035097; C:histone methyltransferase complex; IDA:MGI. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |