| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
361 | A7XUJ6 | 541 | TRAF6_PIG TNF receptor-associated factor 6 OS... | 37 | 6.8 | 33.5 | 35 | 49 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 362 | Q1JPS1 | 232 | PCF5B_DANRE Polycomb group RING finger protei... | 48 | 6.8 | 33.1 | 31 | 38 | GO:0031519; C:PcG protein complex; ISS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 363 | Q9Y4K3 | 522 | TRAF6_HUMAN TNF receptor-associated factor 6 ... | 37 | 6.9 | 33.5 | 35 | 49 | GO:0035631; C:CD40 receptor complex; ISS:BHF-UCL.::GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0010008; C:endosome membrane; TAS:Reactome.::GO:0009898; C:internal side of plasma membrane; ISS:BHF-UCL.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL. | | | | | | | | | | GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:UniProtKB.::GO:0043422; F:protein kinase B binding; IPI:UniProtKB.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; TAS:Reactome.::GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IMP:UniProtKB.::GO:0006916; P:anti-apoptosis; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0007254; P:JNK cascade; TAS:Reactome.::GO:0031293; P:membrane protein intracellular domain proteolysis; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.::GO:0001503; P:ossification; IEA:UniProtKB-KW.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB.::GO:0032743; P:positive regulation of interleukin-2 production; IMP:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; NAS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0045672; P:positive regulation of osteoclast differentiation; IDA:UniProtKB.::GO:0050870; P:positive regulation of T cell activation; IC:UniProtKB.::GO:0002726; P:positive regulation of T cell cytokine production; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:2000679; P:positive regulation of transcription regulatory region DNA binding; IDA:BHF-UCL.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0070555; P:response to interleukin-1; IDA:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IMP:UniProtKB.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 364 | B3DK16 | 234 | PCF5A_DANRE Polycomb group RING finger protei... | 48 | 6.9 | 33.1 | 27 | 42 | GO:0031519; C:PcG protein complex; ISS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 365 | Q11096 | 347 | YWZ6_CAEEL Uncharacterized RING finger protei... | 52 | 6.9 | 33.5 | 25 | 46 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 366 | B6CJY5 | 522 | TRAF6_MACMU TNF receptor-associated factor 6 ... | 37 | 6.9 | 33.5 | 35 | 49 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro. | 367 | B6CJY4 | 522 | TRAF6_CERAT TNF receptor-associated factor 6 ... | 37 | 7.1 | 33.5 | 35 | 49 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 368 | A4SGR9 | 473 | MNME_PROVI tRNA modification GTPase MnmE OS=(... | 115 | 7.4 | 33.5 | 31 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006400; P:tRNA modification; IEA:InterPro. | 369 | Q1L721 | 222 | RN138_XENLA E3 ubiquitin-protein ligase RNF13... | 59 | 7.5 | 32.7 | 29 | 44 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 370 | Q9FVS2 | 660 | ORTH3_ARATH E3 ubiquitin-protein ligase ORTHR... | 63 | 7.7 | 33.5 | 30 | 40 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0008327; F:methyl-CpG binding; ISS:UniProtKB.::GO:0010428; F:methyl-CpNpG binding; ISS:UniProtKB.::GO:0010429; F:methyl-CpNpN binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0010424; P:DNA methylation on cytosine within a CG sequence; ISS:UniProtKB. | 371 | Q7T308 | 474 | RN168_DANRE E3 ubiquitin-protein ligase RNF16... | 56 | 7.9 | 33.5 | 32 | 36 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0070535; P:histone H2A K63-linked ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB. | 372 | Q9C029 | 511 | TRIM7_HUMAN Tripartite motif-containing prote... | 27 | 7.9 | 33.5 | 41 | 56 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 373 | P18520 | 520 | ION3_CARAU Intermediate filament protein ON3 ... | 71 | 8 | 33.5 | 37 | 59 | GO:0045095; C:keratin filament; IEA:InterPro. | | | | | | | | | | GO:0005198; F:structural molecule activity; IEA:InterPro. | | | | | | | | | | GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 374 | Q21443 | 566 | LMN1_CAEEL Lamin-1 OS=Caenorhabditis elegans.... | 380 | 8.1 | 33.5 | 26 | 43 | GO:0005638; C:lamin filament; ISS:WormBase.::GO:0005637; C:nuclear inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042393; F:histone binding; IDA:WormBase.::GO:0005198; F:structural molecule activity; IMP:WormBase. | | | | | | | | | | GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0000910; P:cytokinesis; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007281; P:germ cell development; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0007067; P:mitosis; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0031081; P:nuclear pore distribution; IMP:WormBase.::GO:0008284; P:positive regulation of cell proliferation; IMP:WormBase.::GO:0051983; P:regulation of chromosome segregation; IMP:WormBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:WormBase.::GO:0071688; P:striated muscle myosin thick filament assembly; IMP:WormBase. | 375 | B0BLU1 | 535 | RN168_XENTR E3 ubiquitin-protein ligase RNF16... | 43 | 9.2 | 33.1 | 30 | 37 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0070535; P:histone H2A K63-linked ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB. | 376 | B0URM0 | 966 | RAPA_HAES2 RNA polymerase-associated protein ... | 35 | 9.4 | 33.5 | 51 | 74 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 377 | O15230 | 3695 | LAMA5_HUMAN Laminin subunit alpha-5 OS=Homo s... | 90 | 9.5 | 33.5 | 30 | 50 | GO:0005615; C:extracellular space; IDA:UniProtKB.::GO:0005606; C:laminin-1 complex; IEA:InterPro.::GO:0043259; C:laminin-10 complex; IDA:UniProtKB.::GO:0043260; C:laminin-11 complex; TAS:BHF-UCL. | | | | | | | | | | GO:0005178; F:integrin binding; IDA:UniProtKB.::GO:0005198; F:structural molecule activity; IC:UniProtKB. | | | | | | | | | | GO:0001525; P:angiogenesis; NAS:UniProtKB.::GO:0008283; P:cell proliferation; NAS:UniProtKB.::GO:0008037; P:cell recognition; NAS:UniProtKB.::GO:0007010; P:cytoskeleton organization; NAS:UniProtKB.::GO:0045446; P:endothelial cell differentiation; NAS:UniProtKB.::GO:0048041; P:focal adhesion assembly; NAS:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; IMP:UniProtKB.::GO:0030155; P:regulation of cell adhesion; IEA:InterPro.::GO:0030334; P:regulation of cell migration; IEA:InterPro.::GO:0045995; P:regulation of embryonic development; IEA:InterPro.::GO:0034446; P:substrate adhesion-dependent cell spreading; IDA:BHF-UCL. | 378 | Q0I5G1 | 966 | RAPA_HAES1 RNA polymerase-associated protein ... | 35 | 9.6 | 33.5 | 51 | 74 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
