| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
331 | Q91829 | 1045 | RAG1_XENLA V(D)J recombination-activating pro... | 46 | 3.1 | 35 | 33 | 43 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0004519; F:endonuclease activity; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0030183; P:B cell differentiation; ISS:UniProtKB.::GO:0010390; P:histone monoubiquitination; ISS:UniProtKB.::GO:0033077; P:T cell differentiation in thymus; ISS:UniProtKB.::GO:0033151; P:V(D)J recombination; ISS:UniProtKB. | 332 | P78317 | 190 | RNF4_HUMAN E3 ubiquitin-protein ligase RNF4 O... | 51 | 3.5 | 33.9 | 33 | 49 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050681; F:androgen receptor binding; NAS:UniProtKB.::GO:0003677; F:DNA binding; ISS:UniProtKB.::GO:0031491; F:nucleosome binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0032184; F:SUMO polymer binding; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:ProtInc. | | | | | | | | | | GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0090234; P:regulation of kinetochore assembly; IMP:UniProtKB.::GO:0090169; P:regulation of spindle assembly; IMP:UniProtKB.::GO:0046685; P:response to arsenic-containing substance; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 333 | Q6NWF6 | 520 | K2C8_DANRE Keratin, type II cytoskeletal 8 OS... | 69 | 3.6 | 34.7 | 38 | 59 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0045095; C:keratin filament; IEA:InterPro.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005198; F:structural molecule activity; IEA:InterPro. | | | | | | | | | | | 334 | Q8BIJ7 | 712 | RUFY1_MOUSE RUN and FYVE domain-containing pr... | 48 | 3.6 | 34.7 | 33 | 44 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008565; F:protein transporter activity; IDA:MGI. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0030100; P:regulation of endocytosis; IDA:MGI. | 335 | A9VN46 | 116 | YABA_BACWK Initiation-control protein yabA OS... | 42 | 3.7 | 32.7 | 36 | 64 | | | | | | | | | | | | | | | | | | | | | GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 336 | B3P8A3 | 758 | SPAST_DROER Spastin OS=Drosophila erecta (Fru... | 61 | 4 | 34.7 | 36 | 49 | GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0008568; F:microtubule-severing ATPase activity; ISS:UniProtKB. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051013; P:microtubule severing; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW. | 337 | A7GJU5 | 116 | YABA_BACCN Initiation-control protein yabA OS... | 37 | 4 | 32.3 | 41 | 65 | | | | | | | | | | | | | | | | | | | | | GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 338 | Q9P1Y6 | 1649 | PHRF1_HUMAN PHD and RING finger domain-contai... | 42 | 4.1 | 34.7 | 36 | 52 | | | | | | | | | | | GO:0070063; F:RNA polymerase binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 339 | O08863 | 600 | BIRC3_MOUSE Baculoviral IAP repeat-containing... | 52 | 4.4 | 34.3 | 40 | 46 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0070266; P:necroptosis; IDA:UniProtKB.::GO:0060546; P:negative regulation of necroptosis; IMP:UniProtKB.::GO:0042326; P:negative regulation of phosphorylation; IMP:UniProtKB.::GO:2000378; P:negative regulation of reactive oxygen species metabolic process; IMP:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro. | 340 | O94264 | 482 | YORF_SCHPO Uncharacterized RING finger protei... | 40 | 4.7 | 34.3 | 33 | 55 | GO:0005847; C:mRNA cleavage and polyadenylation specificity factor complex; ISS:PomBase. | | | | | | | | | | GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006379; P:mRNA cleavage; ISS:PomBase.::GO:0006378; P:mRNA polyadenylation; ISS:PomBase.::GO:0016567; P:protein ubiquitination; NAS:PomBase. | 341 | O15541 | 343 | R113A_HUMAN RING finger protein 113A OS=Homo ... | 24 | 4.7 | 33.9 | 42 | 54 | | | | | | | | | | | GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 342 | B5DF45 | 530 | TRAF6_RAT TNF receptor-associated factor 6 OS... | 37 | 4.9 | 34.3 | 35 | 49 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070498; P:interleukin-1-mediated signaling pathway; IMP:RGD.::GO:0007254; P:JNK cascade; IMP:RGD.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:RGD.::GO:0006461; P:protein complex assembly; IMP:RGD.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro. | 343 | Q7M3S9 | 943 | RNGB_DICDI RING finger protein B OS=Dictyoste... | 124 | 5 | 34.3 | 29 | 41 | GO:0005737; C:cytoplasm; TAS:dictyBase. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 344 | Q28DL4 | 558 | TRAF6_XENTR TNF receptor-associated factor 6 ... | 37 | 5.1 | 34.3 | 35 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 345 | P31244 | 790 | RAD16_YEAST DNA repair protein RAD16 OS=Sacch... | 46 | 5.1 | 34.3 | 28 | 46 | GO:0031463; C:Cul3-RING ubiquitin ligase complex; IDA:SGD.::GO:0000113; C:nucleotide-excision repair factor 4 complex; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000715; P:nucleotide-excision repair, DNA damage recognition; IDA:SGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:SGD. | 346 | Q55G16 | 355 | RN113_DICDI RING finger protein 113 homolog O... | 44 | 5.3 | 33.9 | 39 | 55 | | | | | | | | | | | GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 347 | P23799 | 630 | ESAG8_TRYBB Putative adenylate cyclase regula... | 44 | 5.3 | 33.9 | 34 | 50 | | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006171; P:cAMP biosynthetic process; IEA:UniProtKB-KW. | 348 | Q05A36 | 652 | MEX3C_MOUSE RNA-binding protein MEX3C OS=Mus ... | 43 | 5.4 | 33.9 | 37 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 349 | Q9BRZ2 | 755 | TRI56_HUMAN E3 ubiquitin-protein ligase TRIM5... | 42 | 5.4 | 33.9 | 29 | 43 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051607; P:defense response to virus; ISS:UniProtKB.::GO:0032608; P:interferon-beta production; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0034340; P:response to type I interferon; ISS:UniProtKB. | 350 | Q13490 | 618 | BIRC2_HUMAN Baculoviral IAP repeat-containing... | 56 | 5.6 | 33.9 | 38 | 46 | GO:0035631; C:CD40 receptor complex; ISS:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0009898; C:internal side of plasma membrane; ISS:BHF-UCL.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0003713; F:transcription coactivator activity; IMP:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0006916; P:anti-apoptosis; TAS:UniProtKB.::GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.::GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0038061; P:NIK/NF-kappaB cascade; TAS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IEP:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0051726; P:regulation of cell cycle; IDA:UniProtKB.::GO:0045595; P:regulation of cell differentiation; TAS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.::GO:2000116; P:regulation of cysteine-type endopeptidase activity; TAS:UniProtKB.::GO:0050727; P:regulation of inflammatory response; TAS:UniProtKB.::GO:0045088; P:regulation of innate immune response; TAS:UniProtKB.::GO:0070424; P:regulation of nucleotide-binding oligomerization domain containing signaling pathway; TAS:UniProtKB.::GO:0039535; P:regulation of RIG-I signaling pathway; TAS:UniProtKB.::GO:0034121; P:regulation of toll-like receptor signaling pathway; TAS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 351 | Q923T7 | 510 | TRIM7_MOUSE Tripartite motif-containing prote... | 27 | 5.6 | 33.9 | 41 | 56 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 352 | Q3ZCC3 | 542 | TRAF6_BOVIN TNF receptor-associated factor 6 ... | 37 | 5.8 | 33.9 | 35 | 49 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro. | 353 | Q5A4N5 | 378 | RAD18_CANAL Postreplication repair E3 ubiquit... | 40 | 5.8 | 33.9 | 35 | 58 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 354 | Q6INS5 | 557 | RN168_XENLA E3 ubiquitin-protein ligase RNF16... | 46 | 5.8 | 33.9 | 30 | 37 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0070535; P:histone H2A K63-linked ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB. | 355 | Q5M7X9 | 341 | MUL1A_DANRE Mitochondrial ubiquitin ligase ac... | 65 | 5.9 | 33.5 | 32 | 46 | GO:0031307; C:integral to mitochondrial outer membrane; ISS:UniProtKB.::GO:0005777; C:peroxisome; ISS:UniProtKB. | | | | | | | | | | GO:0042802; F:identical protein binding; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0000266; P:mitochondrial fission; ISS:UniProtKB.::GO:0051646; P:mitochondrion localization; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB. | 356 | Q5U5Q3 | 659 | MEX3C_HUMAN RNA-binding protein MEX3C OS=Homo... | 43 | 6 | 33.9 | 37 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 357 | E1BD59 | 732 | TRI56_BOVIN E3 ubiquitin-protein ligase TRIM5... | 42 | 6 | 33.9 | 29 | 43 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051607; P:defense response to virus; ISS:UniProtKB.::GO:0032608; P:interferon-beta production; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0034340; P:response to type I interferon; ISS:UniProtKB. | 358 | P70196 | 530 | TRAF6_MOUSE TNF receptor-associated factor 6 ... | 37 | 6.2 | 33.9 | 35 | 49 | GO:0035631; C:CD40 receptor complex; IDA:BHF-UCL.::GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0009898; C:internal side of plasma membrane; IDA:BHF-UCL.::GO:0005624; C:membrane fraction; IDA:UniProtKB. | | | | | | | | | | GO:0004871; F:signal transducer activity; TAS:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; IMP:MGI.::GO:0045453; P:bone resorption; IMP:UniProtKB.::GO:0048468; P:cell development; IMP:MGI.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0070498; P:interleukin-1-mediated signaling pathway; IMP:UniProtKB.::GO:0043011; P:myeloid dendritic cell differentiation; IMP:MGI.::GO:0001843; P:neural tube closure; IMP:UniProtKB.::GO:0042475; P:odontogenesis of dentin-containing tooth; IMP:MGI.::GO:0001503; P:ossification; IMP:MGI.::GO:0030316; P:osteoclast differentiation; IMP:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0045084; P:positive regulation of interleukin-12 biosynthetic process; IMP:MGI.::GO:0045410; P:positive regulation of interleukin-6 biosynthetic process; IMP:MGI.::GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; IMP:UniProtKB.::GO:0042102; P:positive regulation of T cell proliferation; IMP:UniProtKB.::GO:0051865; P:protein autoubiquitination; TAS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0051023; P:regulation of immunoglobulin secretion; IDA:MGI.::GO:0042088; P:T-helper 1 type immune response; IMP:MGI. | 359 | Q5EBN2 | 209 | TRI61_HUMAN Putative tripartite motif-contain... | 37 | 6.3 | 33.1 | 41 | 54 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 360 | Q6BYU0 | 232 | CWC24_DEBHA Pre-mRNA-splicing factor CWC24 OS... | 42 | 6.7 | 33.1 | 33 | 55 | GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 361 | A7XUJ6 | 541 | TRAF6_PIG TNF receptor-associated factor 6 OS... | 37 | 6.8 | 33.5 | 35 | 49 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. |
