rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | O43024 | 963 | YGVA_SCHPO CUE domain-containing protein C354... | 326 | 0.000000002 | 65.5 | 26 | 40 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; ISS:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0000723; P:telomere maintenance; ISS:PomBase.::GO:0006283; P:transcription-coupled nucleotide-excision repair; ISS:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:PomBase. | 2 | Q6FIN4 | 592 | DEF1_CANGA RNA polymerase II degradation fact... | 54 | 0.0002 | 48.9 | 35 | 57 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 3 | C5DGU9 | 733 | DEF1_LACTC RNA polymerase II degradation fact... | 56 | 0.001 | 46.6 | 34 | 63 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 4 | Q75DE9 | 705 | DEF1_ASHGO RNA polymerase II degradation fact... | 63 | 0.003 | 45.1 | 30 | 57 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 5 | A2ASS6 | 35213 | TITIN_MOUSE Titin OS=Mus musculus (Mouse). GN... | 146 | 1.5 | 36.6 | 23 | 40 | GO:0031430; C:M band; IDA:MGI.::GO:0005859; C:muscle myosin complex; TAS:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IDA:MGI. | | | | | | | | | | GO:0030506; F:ankyrin binding; IPI:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005200; F:structural constituent of cytoskeleton; TAS:MGI. | | | | | | | | | | GO:0007512; P:adult heart development; IMP:MGI.::GO:0055003; P:cardiac myofibril assembly; IMP:MGI.::GO:0043056; P:forward locomotion; IMP:MGI.::GO:0003007; P:heart morphogenesis; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0006936; P:muscle contraction; IMP:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0045214; P:sarcomere organization; IMP:MGI.::GO:0001756; P:somitogenesis; IEP:BHF-UCL. | 6 | Q6CTH5 | 645 | DEF1_KLULA RNA polymerase II degradation fact... | 54 | 0.014 | 42.7 | 33 | 61 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 7 | Q8WZ42 | 34350 | TITIN_HUMAN Titin OS=Homo sapiens (Human). GN... | 89 | 3.3 | 35.4 | 26 | 43 | GO:0000794; C:condensed nuclear chromosome; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005576; C:extracellular region; TAS:Reactome.::GO:0031430; C:M band; IDA:BHF-UCL.::GO:0005865; C:striated muscle thin filament; IDA:BHF-UCL.::GO:0030018; C:Z disc; IDA:UniProtKB. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:BHF-UCL.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IDA:BHF-UCL.::GO:0005516; F:calmodulin binding; TAS:UniProtKB.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0051371; F:muscle alpha-actinin binding; IPI:BHF-UCL.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0002020; F:protease binding; IPI:UniProtKB.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0043621; F:protein self-association; IDA:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0008307; F:structural constituent of muscle; TAS:UniProtKB.::GO:0031433; F:telethonin binding; ISS:BHF-UCL. | | | | | | | | | | GO:0048739; P:cardiac muscle fiber development; IMP:BHF-UCL.::GO:0055008; P:cardiac muscle tissue morphogenesis; IMP:BHF-UCL.::GO:0055003; P:cardiac myofibril assembly; IMP:BHF-UCL.::GO:0007076; P:mitotic chromosome condensation; IEP:BHF-UCL.::GO:0030049; P:muscle filament sliding; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0002576; P:platelet degranulation; TAS:Reactome.::GO:0045859; P:regulation of protein kinase activity; IMP:BHF-UCL.::GO:0051592; P:response to calcium ion; IDA:BHF-UCL.::GO:0045214; P:sarcomere organization; IMP:BHF-UCL.::GO:0048769; P:sarcomerogenesis; IMP:BHF-UCL.::GO:0030241; P:skeletal muscle myosin thick filament assembly; IMP:BHF-UCL.::GO:0030240; P:skeletal muscle thin filament assembly; IMP:BHF-UCL.::GO:0006941; P:striated muscle contraction; TAS:UniProtKB. | 8 | C7GP20 | 738 | DEF1_YEAS2 RNA polymerase II degradation fact... | 55 | 0.031 | 42 | 33 | 56 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 9 | O01761 | 8081 | UNC89_CAEEL Muscle M-line assembly protein un... | 125 | 0.33 | 38.9 | 29 | 51 | GO:0005887; C:integral to plasma membrane; IEA:InterPro.::GO:0031430; C:M band; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:InterPro.::GO:0019902; F:phosphatase binding; IPI:WormBase.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017048; F:Rho GTPase binding; IPI:WormBase.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IDA:WormBase.::GO:0005021; F:vascular endothelial growth factor-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0040011; P:locomotion; IMP:WormBase.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0030241; P:skeletal muscle myosin thick filament assembly; IMP:WormBase.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IEA:InterPro. | 10 | P35732 | 738 | DEF1_YEAST RNA polymerase II degradation fact... | 55 | 0.033 | 41.6 | 33 | 56 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IMP:SGD. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0000723; P:telomere maintenance; IMP:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:SGD. | 11 | A6ZZR2 | 733 | DEF1_YEAS7 RNA polymerase II degradation fact... | 47 | 0.035 | 41.6 | 32 | 60 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 12 | Q008X6 | 6872 | R1AB_WBV24 Replicase polyprotein 1ab OS=White... | 81 | 0.097 | 40.4 | 33 | 44 | GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0032774; P:RNA biosynthetic process; IEA:UniProtKB-KW. | 13 | Q008X5 | 4555 | R1A_WBV24 Replicase polyprotein 1a OS=White b... | 81 | 0.12 | 40 | 33 | 44 | GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 14 | Q9WVL2 | 923 | STAT2_MOUSE Signal transducer and activator o... | 119 | 0.8 | 37.4 | 31 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 15 | Q12639 | 299 | PELA_MYCPO Pectin lyase OS=Mycosphaerella pin... | 143 | 0.82 | 36.6 | 24 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047490; F:pectin lyase activity; IEA:EC. | | | | | | | | | | | 16 | Q3KR59 | 794 | UBP10_RAT Ubiquitin carboxyl-terminal hydrola... | 172 | 2.2 | 35.8 | 29 | 39 | GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0042980; F:cystic fibrosis transmembrane conductance regulator binding; ISS:UniProtKB.::GO:0002039; F:p53 binding; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB. | | | | | | | | | | GO:0030330; P:DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 17 | Q2NL57 | 791 | UB10A_XENLA Ubiquitin carboxyl-terminal hydro... | 131 | 4 | 35 | 31 | 43 | GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0042980; F:cystic fibrosis transmembrane conductance regulator binding; ISS:UniProtKB.::GO:0002039; F:p53 binding; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB. | | | | | | | | | | GO:0030330; P:DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 18 | Q5UQ88 | 1441 | UBC3_MIMIV Probable ubiquitin-conjugating enz... | 46 | 5.5 | 34.7 | 43 | 65 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC. | | | | | | | | | | GO:0042262; P:DNA protection; IEA:InterPro. | 19 | C5M2B8 | 769 | DEF1_CANTT RNA polymerase II degradation fact... | 39 | 6.3 | 34.3 | 28 | 51 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 20 | Q6BRB3 | 742 | DEF1_DEBHA RNA polymerase II degradation fact... | 42 | 6.7 | 34.3 | 31 | 55 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 21 | Q50360 | 672 | HMW3_MYCPN Cytadherence high molecular weight... | 129 | 9.9 | 33.5 | 30 | 38 | GO:0033111; C:attachment organelle membrane; IEA:UniProtKB-SubCell.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0020035; P:cytoadherence to microvasculature, mediated by symbiont protein; IEA:UniProtKB-KW.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW. |