rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | Q04520 | 241 | BUDC_RAOTE Diacetyl reductase [(S)-acetoin fo... | 218 | 2e-21 | 94.7 | 35 | 52 | | | | | | | | | | | GO:0052588; F:diacetyl reductase ((S)-acetoin forming) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045150; P:acetoin catabolic process; IEA:InterPro. | 92 | Q8VCC1 | 269 | PGDH_MOUSE 15-hydroxyprostaglandin dehydrogen... | 205 | 2e-21 | 95.1 | 32 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0097070; P:ductus arteriosus closure; IMP:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; ISS:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB. | 93 | P69167 | 260 | HSD_MYCTU 3-alpha-(or 20-beta)-hydroxysteroid... | 262 | 3e-21 | 94.4 | 34 | 50 | GO:0005886; C:plasma membrane; IDA:MTBBASE. | | | | | | | | | | GO:0047044; F:androstan-3-alpha,17-beta-diol dehydrogenase activity; IDA:MTBBASE.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IDA:MTBBASE. | 94 | P69166 | 260 | HSD_MYCBO 3-alpha-(or 20-beta)-hydroxysteroid... | 262 | 3e-21 | 94.4 | 34 | 50 | | | | | | | | | | | GO:0047044; F:androstan-3-alpha,17-beta-diol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 95 | P55541 | 278 | Y4LA_RHISN Uncharacterized short-chain type d... | 262 | 3e-21 | 94.7 | 30 | 48 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 96 | C1C4R8 | 245 | BDH2_LITCT 3-hydroxybutyrate dehydrogenase ty... | 261 | 4e-21 | 93.6 | 31 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003858; F:3-hydroxybutyrate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; ISS:UniProtKB. | | | | | | | | | | GO:0042168; P:heme metabolic process; ISS:UniProtKB.::GO:0055072; P:iron ion homeostasis; ISS:UniProtKB.::GO:0019290; P:siderophore biosynthetic process; ISS:UniProtKB. | 97 | Q9WVK3 | 303 | PECR_RAT Peroxisomal trans-2-enoyl-CoA reduct... | 273 | 4e-21 | 94.4 | 30 | 48 | GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005777; C:peroxisome; IDA:HGNC. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0019166; F:trans-2-enoyl-CoA reductase (NADPH) activity; IEA:EC. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 98 | O67610 | 248 | FABG_AQUAE 3-oxoacyl-[acyl-carrier-protein] r... | 256 | 4e-21 | 93.6 | 28 | 50 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.] | 99 | Q7TS56 | 236 | CBR4_RAT Carbonyl reductase family member 4 O... | 247 | 6e-21 | 93.2 | 29 | 47 | GO:0005759; C:mitochondrial matrix; ISS:UniProtKB. | | | | | | | | | | GO:0070402; F:NADPH binding; ISS:UniProtKB.::GO:0008753; F:NADPH dehydrogenase (quinone) activity; ISS:UniProtKB.::GO:0048038; F:quinone binding; ISS:UniProtKB. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 100 | P37769 | 253 | KDUD_ECOLI 2-dehydro-3-deoxy-D-gluconate 5-de... | 266 | 7e-21 | 93.2 | 31 | 49 | | | | | | | | | | | GO:0047001; F:2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase activity; IEA:EC.::GO:0008678; F:2-deoxy-D-gluconate 3-dehydrogenase activity; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 101 | P19871 | 254 | 3BHD_COMTE 3-beta-hydroxysteroid dehydrogenas... | 264 | 1e-20 | 92.4 | 33 | 49 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0030283; F:testosterone dehydrogenase [NAD(P) activity; IEA:EC. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW.] | 102 | O31680 | 248 | YKVO_BACSU Uncharacterized oxidoreductase ykv... | 258 | 1e-20 | 92.4 | 29 | 46 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 103 | Q68VY7 | 241 | FABG_RICTY 3-oxoacyl-[acyl-carrier-protein] r... | 256 | 1e-20 | 92 | 29 | 50 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.] | 104 | P43713 | 242 | FABG_HAEIN 3-oxoacyl-[acyl-carrier-protein] r... | 257 | 1e-20 | 92 | 29 | 51 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.] | 105 | P73574 | 247 | FABG1_SYNY3 3-oxoacyl-[acyl-carrier-protein] ... | 263 | 1e-20 | 92 | 32 | 49 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.] | 106 | P66776 | 258 | BUTA_STAAW Diacetyl reductase [(S)-acetoin fo... | 263 | 2e-20 | 92 | 32 | 48 | | | | | | | | | | | GO:0052588; F:diacetyl reductase ((S)-acetoin forming) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045150; P:acetoin catabolic process; IEA:InterPro. | 107 | Q6GCZ8 | 258 | BUTA_STAAS Diacetyl reductase [(S)-acetoin fo... | 263 | 2e-20 | 92 | 32 | 48 | | | | | | | | | | | GO:0052588; F:diacetyl reductase ((S)-acetoin forming) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045150; P:acetoin catabolic process; IEA:InterPro. | 108 | Q6GKH9 | 258 | BUTA_STAAR Diacetyl reductase [(S)-acetoin fo... | 263 | 2e-20 | 92 | 32 | 48 | | | | | | | | | | | GO:0052588; F:diacetyl reductase ((S)-acetoin forming) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045150; P:acetoin catabolic process; IEA:InterPro. | 109 | P99120 | 258 | BUTA_STAAN Diacetyl reductase [(S)-acetoin fo... | 263 | 2e-20 | 92 | 32 | 48 | | | | | | | | | | | GO:0052588; F:diacetyl reductase ((S)-acetoin forming) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045150; P:acetoin catabolic process; IEA:InterPro. | 110 | P66775 | 258 | BUTA_STAAM Diacetyl reductase [(S)-acetoin fo... | 263 | 2e-20 | 92 | 32 | 48 | | | | | | | | | | | GO:0052588; F:diacetyl reductase ((S)-acetoin forming) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045150; P:acetoin catabolic process; IEA:InterPro. | 111 | Q5HJP2 | 258 | BUTA_STAAC Diacetyl reductase [(S)-acetoin fo... | 263 | 2e-20 | 92 | 32 | 48 | | | | | | | | | | | GO:0052588; F:diacetyl reductase ((S)-acetoin forming) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045150; P:acetoin catabolic process; IEA:InterPro. | 112 | Q05528 | 253 | KDUD_DICD3 2-dehydro-3-deoxy-D-gluconate 5-de... | 260 | 2e-20 | 91.7 | 29 | 50 | | | | | | | | | | | GO:0047001; F:2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase activity; IEA:EC.::GO:0008678; F:2-deoxy-D-gluconate 3-dehydrogenase activity; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 113 | Q45219 | 281 | Y2146_BRAJA Probable short-chain type dehydro... | 265 | 2e-20 | 92 | 30 | 48 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 114 | Q8K9J5 | 244 | FABG_BUCAP 3-oxoacyl-[acyl-carrier-protein] r... | 261 | 3e-20 | 91.3 | 27 | 51 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.] | 115 | A0R518 | 279 | Y6031_MYCS2 Putative short-chain type dehydro... | 284 | 5e-20 | 90.9 | 29 | 47 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 116 | Q6NUE2 | 236 | CBR4_XENLA Carbonyl reductase family member 4... | 239 | 6e-20 | 90.1 | 28 | 48 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 117 | Q9BTZ2 | 278 | DHRS4_HUMAN Dehydrogenase/reductase SDR famil... | 263 | 6e-20 | 90.5 | 32 | 48 | GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005777; C:peroxisome; IDA:UniProtKB. | | | | | | | | | | GO:0000253; F:3-keto sterol reductase activity; IDA:UniProtKB.::GO:0018455; F:alcohol dehydrogenase [NAD(P)+ activity; IDA:UniProtKB.::GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IDA:UniProtKB.::GO:0042180; P:cellular ketone metabolic process; IDA:UniProtKB.::GO:0051262; P:protein tetramerization; IDA:UniProtKB.::GO:0008202; P:steroid metabolic process; IDA:UniProtKB.] | 118 | Q5RCF8 | 278 | DHRS4_PONAB Dehydrogenase/reductase SDR famil... | 263 | 7e-20 | 90.5 | 32 | 48 | GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 119 | Q5TJF5 | 259 | DHB8_CANFA Estradiol 17-beta-dehydrogenase 8 ... | 262 | 7e-20 | 90.1 | 31 | 48 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC. | | | | | | | | | | GO:0006703; P:estrogen biosynthetic process; ISS:UniProtKB.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 120 | Q92506 | 261 | DHB8_HUMAN Estradiol 17-beta-dehydrogenase 8 ... | 262 | 7e-20 | 90.1 | 31 | 48 | GO:0005759; C:mitochondrial matrix; IDA:UniProtKB. | | | | | | | | | | GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IDA:UniProtKB.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC. | | | | | | | | | | GO:0006703; P:estrogen biosynthetic process; IDA:UniProtKB.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 121 | P50941 | 241 | FABG_RICPR 3-oxoacyl-[acyl-carrier-protein] r... | 256 | 7e-20 | 89.7 | 30 | 50 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.] |