| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q08023 | 583 | FMP25_YEAST Protein FMP25, mitochondrial OS=S... | 428 | 2e-23 | 108 | 25 | 42 | GO:0031305; C:integral to mitochondrial inner membrane; IDA:SGD. | | | | | | | | | | | | | | | | | | | | GO:0034551; P:mitochondrial respiratory chain complex III assembly; IMP:SGD. | 2 | Q5PQN1 | 1057 | HERC4_RAT Probable E3 ubiquitin-protein ligas... | 415 | 0.002 | 45.1 | 24 | 36 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; ISS:UniProtKB. | 3 | Q6PAV2 | 1057 | HERC4_MOUSE Probable E3 ubiquitin-protein lig... | 251 | 0.18 | 38.5 | 22 | 39 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; TAS:UniProtKB. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; IMP:UniProtKB. | 4 | Q8IVU3 | 1022 | HERC6_HUMAN Probable E3 ubiquitin-protein lig... | 243 | 0.057 | 40 | 23 | 39 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 5 | Q3MHW0 | 464 | SRGEF_BOVIN Secretion-regulating guanine nucl... | 322 | 0.014 | 42 | 25 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 6 | Q5GLZ8 | 1057 | HERC4_HUMAN Probable E3 ubiquitin-protein lig... | 251 | 0.91 | 36.2 | 22 | 39 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; ISS:UniProtKB. | 7 | P21827 | 482 | RCC1_YEAST Guanine nucleotide exchange factor... | 95 | 4.5 | 33.9 | 27 | 44 | GO:0000790; C:nuclear chromatin; IDA:SGD. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IMP:SGD. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.::GO:0000054; P:ribosomal subunit export from nucleus; IMP:SGD.::GO:0006407; P:rRNA export from nucleus; IMP:SGD. | 8 | Q15034 | 1050 | HERC3_HUMAN Probable E3 ubiquitin-protein lig... | 251 | 0.0005 | 47 | 25 | 40 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 9 | Q5BIW4 | 1657 | ALS2_PANTR Alsin OS=Pan troglodytes (Chimpanz... | 211 | 0.11 | 39.3 | 24 | 40 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0043234; C:protein complex; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB.::GO:0042598; C:vesicular fraction; ISS:UniProtKB. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043539; F:protein serine/threonine kinase activator activity; ISS:UniProtKB.::GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; ISS:UniProtKB.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0001662; P:behavioral fear response; ISS:UniProtKB.::GO:0016197; P:endosome transport; ISS:UniProtKB.::GO:0007626; P:locomotory behavior; ISS:UniProtKB.::GO:0007528; P:neuromuscular junction development; ISS:UniProtKB.::GO:0048812; P:neuron projection morphogenesis; ISS:UniProtKB.::GO:0032855; P:positive regulation of Rac GTPase activity; ISS:UniProtKB.::GO:0008104; P:protein localization; ISS:UniProtKB.::GO:0001881; P:receptor recycling; ISS:UniProtKB.::GO:0051036; P:regulation of endosome size; ISS:UniProtKB.::GO:0032313; P:regulation of Rab GTPase activity; ISS:UniProtKB.::GO:0006979; P:response to oxidative stress; ISS:UniProtKB.::GO:0035249; P:synaptic transmission, glutamatergic; ISS:UniProtKB.::GO:0016050; P:vesicle organization; ISS:UniProtKB. | 10 | Q8VE37 | 421 | RCC1_MOUSE Regulator of chromosome condensati... | 383 | 0.00001 | 51.6 | 23 | 36 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0031492; F:nucleosomal DNA binding; ISS:UniProtKB.::GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; IDA:MGI. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051225; P:spindle assembly; ISS:UniProtKB. | 11 | Q96Q42 | 1657 | ALS2_HUMAN Alsin OS=Homo sapiens (Human). GN=... | 211 | 0.12 | 39.3 | 24 | 40 | GO:0005813; C:centrosome; IDA:MGI.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0030426; C:growth cone; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0043234; C:protein complex; IDA:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0043539; F:protein serine/threonine kinase activator activity; IDA:UniProtKB.::GO:0017137; F:Rab GTPase binding; IDA:UniProtKB.::GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IDA:UniProtKB.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IDA:UniProtKB.::GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; NAS:UniProtKB. | | | | | | | | | | GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0007032; P:endosome organization; NAS:UniProtKB.::GO:0032855; P:positive regulation of Rac GTPase activity; IDA:UniProtKB.::GO:0035022; P:positive regulation of Rac protein signal transduction; IC:UniProtKB.::GO:0051036; P:regulation of endosome size; IEP:UniProtKB. | 12 | P23800 | 421 | RCC1_MESAU Regulator of chromosome condensati... | 384 | 0.00002 | 51.2 | 23 | 37 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0031492; F:nucleosomal DNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051225; P:spindle assembly; ISS:UniProtKB. | 13 | P18754 | 421 | RCC1_HUMAN Regulator of chromosome condensati... | 384 | 0.00003 | 50.4 | 23 | 37 | GO:0000794; C:condensed nuclear chromosome; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0000790; C:nuclear chromatin; IDA:UniProtKB.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0031492; F:nucleosomal DNA binding; IDA:UniProtKB.::GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; IDA:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IMP:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007052; P:mitotic spindle organization; IDA:UniProtKB.::GO:0007088; P:regulation of mitosis; IDA:UniProtKB.::GO:0007090; P:regulation of S phase of mitotic cell cycle; IMP:UniProtKB.::GO:0051225; P:spindle assembly; IMP:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome. | 14 | Q4U2R1 | 4836 | HERC2_MOUSE E3 ubiquitin-protein ligase HERC2... | 271 | 2.9 | 34.7 | 26 | 39 | GO:0005743; C:mitochondrial inner membrane; IDA:MGI.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; IMP:MGI. | 15 | O95714 | 4834 | HERC2_HUMAN E3 ubiquitin-protein ligase HERC2... | 271 | 8.6 | 33.1 | 26 | 39 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; NAS:UniProtKB.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IDA:UniProtKB.::GO:0006886; P:intracellular protein transport; NAS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 16 | Q8TD19 | 979 | NEK9_HUMAN Serine/threonine-protein kinase Ne... | 206 | 0.068 | 40 | 23 | 40 | GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 17 | Q9UGK8 | 458 | SRGEF_HUMAN Secretion-regulating guanine nucl... | 133 | 3.3 | 34.3 | 33 | 44 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; TAS:UniProtKB. | | | | | | | | | | GO:0050709; P:negative regulation of protein secretion; IDA:HGNC.::GO:0007165; P:signal transduction; TAS:UniProtKB. | 18 | P28745 | 539 | RCC1_SCHPO Protein pim1 OS=Schizosaccharomyce... | 324 | 0.00008 | 49.3 | 25 | 39 | GO:0000790; C:nuclear chromatin; NAS:PomBase. | | | | | | | | | | GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; IGI:PomBase. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; IMP:PomBase.::GO:0006406; P:mRNA export from nucleus; IMP:PomBase.::GO:0031291; P:Ran protein signal transduction; IGI:PomBase.::GO:0060623; P:regulation of chromosome condensation; IGI:PomBase.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IMP:PomBase.::GO:0006407; P:rRNA export from nucleus; ISS:PomBase.::GO:0090307; P:spindle assembly involved in mitosis; TAS:PomBase. | 19 | Q8K1R7 | 984 | NEK9_MOUSE Serine/threonine-protein kinase Ne... | 207 | 0.088 | 39.7 | 23 | 39 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 20 | Q54X24 | 512 | RCCDA_DICDI RCC1 domain-containing protein DD... | 36 | 3 | 34.3 | 47 | 64 | | | | | | | | | | | | | | | | | | | | | | 21 | P0C5Y8 | 1651 | ALS2_RAT Alsin OS=Rattus norvegicus (Rat). GN... | 230 | 0.4 | 37.7 | 25 | 41 | GO:0030424; C:axon; IDA:RGD.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0030426; C:growth cone; IDA:UniProtKB.::GO:0016020; C:membrane; IDA:UniProtKB.::GO:0005792; C:microsome; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0043234; C:protein complex; ISS:UniProtKB.::GO:0019717; C:synaptosome; IDA:RGD. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043539; F:protein serine/threonine kinase activator activity; ISS:UniProtKB.::GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; ISS:UniProtKB.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007409; P:axonogenesis; IMP:RGD.::GO:0008219; P:cell death; IMP:RGD.::GO:0001701; P:in utero embryonic development; IEP:RGD.::GO:0032855; P:positive regulation of Rac GTPase activity; ISS:UniProtKB.::GO:0016601; P:Rac protein signal transduction; IDA:RGD.::GO:0051036; P:regulation of endosome size; ISS:UniProtKB. | 22 | Q920R0 | 1651 | ALS2_MOUSE Alsin OS=Mus musculus (Mouse). GN=... | 229 | 0.51 | 37.4 | 26 | 42 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0030426; C:growth cone; ISS:UniProtKB.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0014069; C:postsynaptic density; IDA:MGI.::GO:0043234; C:protein complex; ISS:UniProtKB.::GO:0001726; C:ruffle; IDA:UniProtKB.::GO:0042598; C:vesicular fraction; ISS:UniProtKB. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043539; F:protein serine/threonine kinase activator activity; ISS:UniProtKB.::GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; ISS:UniProtKB.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0001662; P:behavioral fear response; IMP:MGI.::GO:0016197; P:endosome transport; IMP:MGI.::GO:0007626; P:locomotory behavior; IMP:MGI.::GO:0007528; P:neuromuscular junction development; IMP:MGI.::GO:0048812; P:neuron projection morphogenesis; ISS:UniProtKB.::GO:0032855; P:positive regulation of Rac GTPase activity; ISS:UniProtKB.::GO:0008104; P:protein localization; IMP:MGI.::GO:0001881; P:receptor recycling; IMP:MGI.::GO:0051036; P:regulation of endosome size; ISS:UniProtKB.::GO:0032313; P:regulation of Rab GTPase activity; IDA:MGI.::GO:0006979; P:response to oxidative stress; IMP:MGI.::GO:0035249; P:synaptic transmission, glutamatergic; IMP:MGI.::GO:0016050; P:vesicle organization; IDA:MGI. | 23 | Q80YD6 | 464 | SRGEF_MOUSE Secretion-regulating guanine nucl... | 444 | 0.0004 | 46.6 | 23 | 35 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 24 | Q9VR91 | 4912 | HERC2_DROME Probable E3 ubiquitin-protein lig... | 67 | 2.7 | 35 | 36 | 45 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome. | 25 | Q6P798 | 551 | RCBT2_RAT RCC1 and BTB domain-containing prot... | 174 | 0.007 | 43.1 | 30 | 43 | | | | | | | | | | | | | | | | | | | | | | 26 | Q8SSY6 | 1887 | SPKUL_DICDI Bifunctional serine/threonine-pro... | 171 | 0.023 | 41.6 | 27 | 43 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 27 | Q15751 | 4861 | HERC1_HUMAN Probable E3 ubiquitin-protein lig... | 429 | 0.27 | 38.1 | 21 | 37 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; TAS:ProtInc.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; TAS:ProtInc. | | | | | | | | | | GO:0006464; P:protein modification process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 28 | Q8BTU7 | 377 | RCCD1_MOUSE RCC1 domain-containing protein 1 ... | 153 | 0.002 | 44.3 | 29 | 44 | | | | | | | | | | | | | | | | | | | | | | 29 | Q99LJ7 | 551 | RCBT2_MOUSE RCC1 and BTB domain-containing pr... | 174 | 0.005 | 43.1 | 30 | 43 | | | | | | | | | | | | | | | | | | | | | | 30 | P0C7G9 | 704 | RCCDB_DICDI RCC1 domain-containing protein DD... | 63 | 0.004 | 43.9 | 41 | 57 | | | | | | | | | | | | | | | | | | | | | | 31 | Q5RCZ7 | 551 | RCBT2_PONAB RCC1 and BTB domain-containing pr... | 173 | 0.007 | 42.7 | 31 | 45 | | | | | | | | | | | | | | | | | | | | | |
