rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q07703 | 396 | METC_BORAV Cystathionine beta-lyase OS=Bordet... | 348 | 0.0002 | 47.8 | 24 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 32 | O31631 | 373 | METI_BACSU Cystathionine gamma-synthase/O-ace... | 255 | 0.0003 | 47.4 | 25 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 33 | Q59829 | 392 | CYSA_STRCO Putative cystathionine gamma-lyase... | 251 | 0.0003 | 47.4 | 26 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004123; F:cystathionine gamma-lyase activity; IEA:EC.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW. | 34 | P38716 | 378 | YHR2_YEAST Uncharacterized trans-sulfuration ... | 283 | 0.0003 | 47 | 22 | 41 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0016829; F:lyase activity; IEA:UniProtKB-KW.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro. | 35 | O13326 | 429 | CYSD_SCHPO O-acetylhomoserine (thiol)-lyase O... | 284 | 0.0005 | 46.6 | 24 | 37 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0004124; F:cysteine synthase activity; ISS:PomBase.::GO:0003961; F:O-acetylhomoserine aminocarboxypropyltransferase activity; TAS:PomBase.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | | 36 | P31373 | 394 | CYS3_YEAST Cystathionine gamma-lyase OS=Sacch... | 255 | 0.0006 | 46.2 | 28 | 43 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0004123; F:cystathionine gamma-lyase activity; IDA:SGD.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0019343; P:cysteine biosynthetic process via cystathionine; IMP:SGD.::GO:0019346; P:transsulfuration; IMP:SGD. | 37 | Q92441 | 444 | MET17_KLULA Protein MET17 OS=1267 / NRRL Y-11... | 298 | 0.003 | 43.9 | 26 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0003961; F:O-acetylhomoserine aminocarboxypropyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | | 38 | Q60HG7 | 405 | CGL_MACFA Cystathionine gamma-lyase OS=Macaca... | 257 | 0.006 | 43.1 | 23 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004123; F:cystathionine gamma-lyase activity; ISS:UniProtKB.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB. | | | | | | | | | | GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0019344; P:cysteine biosynthetic process; ISS:UniProtKB.::GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0044524; P:protein sulfhydration; ISS:UniProtKB.::GO:0018272; P:protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; ISS:UniProtKB. | 39 | P44527 | 396 | METC_HAEIN Cystathionine beta-lyase OS=Haemop... | 224 | 0.012 | 42 | 24 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 40 | P06721 | 395 | METC_ECOLI Cystathionine beta-lyase metC OS=E... | 337 | 0.016 | 41.6 | 23 | 37 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004121; F:cystathionine beta-lyase activity; IDA:EcoCyc.::GO:0080146; F:L-cysteine desulfhydrase activity; IMP:EcoCyc.::GO:0030170; F:pyridoxal phosphate binding; IDA:EcoCyc. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 41 | P32929 | 405 | CGL_HUMAN Cystathionine gamma-lyase OS=Homo s... | 257 | 0.09 | 39.3 | 24 | 41 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004123; F:cystathionine gamma-lyase activity; IDA:UniProtKB.::GO:0047982; F:homocysteine desulfhydrase activity; TAS:Reactome.::GO:0080146; F:L-cysteine desulfhydrase activity; TAS:Reactome.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IMP:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IDA:UniProtKB. | | | | | | | | | | GO:0019344; P:cysteine biosynthetic process; IDA:UniProtKB.::GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:UniProtKB.::GO:0070814; P:hydrogen sulfide biosynthetic process; IDA:UniProtKB.::GO:0051289; P:protein homotetramerization; IPI:UniProtKB.::GO:0044524; P:protein sulfhydration; IMP:UniProtKB.::GO:0018272; P:protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; IDA:UniProtKB.::GO:0000098; P:sulfur amino acid catabolic process; TAS:Reactome.::GO:0019346; P:transsulfuration; TAS:Reactome. | 42 | Q58DW2 | 405 | CGL_BOVIN Cystathionine gamma-lyase OS=Bos ta... | 234 | 0.17 | 38.5 | 24 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004123; F:cystathionine gamma-lyase activity; ISS:UniProtKB.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB. | | | | | | | | | | GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0019344; P:cysteine biosynthetic process; ISS:UniProtKB.::GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0044524; P:protein sulfhydration; ISS:UniProtKB.::GO:0018272; P:protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; ISS:UniProtKB. | 43 | P53101 | 465 | STR3_YEAST Cystathionine beta-lyase OS=Saccha... | 94 | 0.21 | 38.1 | 30 | 48 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005777; C:peroxisome; IDA:SGD. | | | | | | | | | | GO:0004121; F:cystathionine beta-lyase activity; IMP:SGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0071266; P:'de novo' L-methionine biosynthetic process; IEA:InterPro.::GO:0019346; P:transsulfuration; IMP:SGD. | 44 | O94350 | 390 | CBL_SCHPO Cystathionine beta-lyase OS=Schizos... | 258 | 0.35 | 37.4 | 23 | 40 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005777; C:peroxisome; ISS:PomBase. | | | | | | | | | | GO:0004121; F:cystathionine beta-lyase activity; ISS:PomBase.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0019279; P:L-methionine biosynthetic process from L-homoserine via cystathionine; IC:PomBase. | 45 | P50125 | 437 | CYSD_EMENI O-acetylhomoserine (thiol)-lyase O... | 280 | 0.5 | 37 | 25 | 35 | | | | | | | | | | | GO:0003961; F:O-acetylhomoserine aminocarboxypropyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW. | 46 | Q52811 | 396 | METC_RHIL3 Putative cystathionine beta-lyase ... | 253 | 1.2 | 35.8 | 23 | 40 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 47 | Q9S3K3 | 467 | SELA_EUBAC L-seryl-tRNA(Sec) selenium transfe... | 64 | 1.2 | 35.8 | 36 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004125; F:L-seryl-tRNASec selenium transferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0001514; P:selenocysteine incorporation; IEA:InterPro. | 48 | P06106 | 444 | MET17_YEAST Protein MET17 OS=Saccharomyces ce... | 148 | 1.7 | 35.4 | 27 | 42 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD. | | | | | | | | | | GO:0004124; F:cysteine synthase activity; IDA:SGD.::GO:0003961; F:O-acetylhomoserine aminocarboxypropyltransferase activity; IDA:SGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | | 49 | Q5P1A9 | 350 | PYRD_AROAE Dihydroorotate dehydrogenase (quin... | 135 | 1.5 | 35.4 | 28 | 43 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro. | 50 | Q9JYH7 | 365 | HIS8_NEIMB Histidinol-phosphate aminotransfer... | 66 | 4.3 | 33.9 | 36 | 48 | | | | | | | | | | | GO:0004400; F:histidinol-phosphate transaminase activity; IEA:EC.::GO:0080130; F:L-phenylalanine:2-oxoglutarate aminotransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW. | 51 | Q75EK2 | 452 | NMT_ASHGO Glycylpeptide N-tetradecanoyltransf... | 95 | 5.3 | 33.5 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004379; F:glycylpeptide N-tetradecanoyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006499; P:N-terminal protein myristoylation; IEA:InterPro. | 52 | B4RJ05 | 359 | HIS8_NEIG2 Histidinol-phosphate aminotransfer... | 66 | 8.4 | 32.7 | 36 | 47 | | | | | | | | | | | GO:0004400; F:histidinol-phosphate transaminase activity; IEA:EC.::GO:0080130; F:L-phenylalanine:2-oxoglutarate aminotransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW. | 53 | Q5F7D7 | 359 | HIS8_NEIG1 Histidinol-phosphate aminotransfer... | 66 | 8.4 | 32.7 | 36 | 47 | | | | | | | | | | | GO:0004400; F:histidinol-phosphate transaminase activity; IEA:EC.::GO:0080130; F:L-phenylalanine:2-oxoglutarate aminotransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW. |