| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
181 | P77212 | 441 | YKGC_ECOLI Probable pyridine nucleotide-disul... | 455 | 3e-46 | 172 | 28 | 51 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016668; F:oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 182 | P43783 | 456 | GSHR_HAEIN Glutathione reductase OS=Haemophil... | 450 | 5e-46 | 172 | 29 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro. | 183 | D0VWY5 | 463 | GASHR_MARGR Glutathione amide reductase OS=Ma... | 458 | 8e-46 | 171 | 30 | 47 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro. | 184 | P48638 | 459 | GSHR_NOSS1 Glutathione reductase OS=Nostoc sp... | 468 | 2e-45 | 170 | 29 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro. | 185 | C4K3I8 | 468 | STHA_HAMD5 Soluble pyridine nucleotide transh... | 472 | 1e-44 | 168 | 29 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 186 | A2TIL1 | 522 | GSHR_CALJA Glutathione reductase, mitochondri... | 533 | 3e-44 | 168 | 28 | 47 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro. | 187 | Q99MD6 | 697 | TRXR3_MOUSE Thioredoxin reductase 3 OS=Mus mu... | 436 | 1e-43 | 167 | 31 | 48 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:MGI. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006749; P:glutathione metabolic process; IDA:MGI.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 188 | P47791 | 500 | GSHR_MOUSE Glutathione reductase, mitochondri... | 477 | 2e-43 | 165 | 27 | 49 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0004362; F:glutathione-disulfide reductase activity; IDA:MGI. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IC:MGI. | 189 | Q9Z0J5 | 526 | TRXR2_RAT Thioredoxin reductase 2, mitochondr... | 465 | 2e-43 | 165 | 29 | 48 | GO:0030424; C:axon; IDA:RGD.::GO:0030425; C:dendrite; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0043025; C:neuronal cell body; IDA:RGD. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:UniProtKB. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0042493; P:response to drug; IEP:RGD.::GO:0042542; P:response to hydrogen peroxide; TAS:RGD.::GO:0000305; P:response to oxygen radical; TAS:UniProtKB.::GO:0010269; P:response to selenium ion; IEP:RGD. | 190 | Q9JLT4 | 524 | TRXR2_MOUSE Thioredoxin reductase 2, mitochon... | 485 | 6e-43 | 164 | 29 | 48 | GO:0005739; C:mitochondrion; IDA:UniProtKB. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004791; F:thioredoxin-disulfide reductase activity; ISS:UniProtKB. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0007507; P:heart development; IMP:MGI.::GO:0030097; P:hemopoiesis; IMP:MGI.::GO:0000305; P:response to oxygen radical; TAS:UniProtKB. | 191 | P06715 | 450 | GSHR_ECOLI Glutathione reductase OS=Escherich... | 444 | 1e-42 | 162 | 30 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IDA:UniProtKB. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro. | 192 | P78965 | 464 | GSHR_SCHPO Glutathione reductase OS=Schizosac... | 470 | 1e-42 | 162 | 30 | 47 | GO:0005739; C:mitochondrion; IDA:PomBase. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IMP:PomBase.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0034599; P:cellular response to oxidative stress; IMP:PomBase.::GO:0006749; P:glutathione metabolic process; IMP:PomBase. | 193 | Q86VQ6 | 682 | TRXR3_HUMAN Thioredoxin reductase 3 OS=Homo s... | 436 | 2e-42 | 164 | 30 | 48 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; NAS:UniProtKB. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045454; P:cell redox homeostasis; NAS:UniProtKB.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 194 | P00390 | 522 | GSHR_HUMAN Glutathione reductase, mitochondri... | 464 | 2e-42 | 162 | 28 | 51 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0004362; F:glutathione-disulfide reductase activity; TAS:Reactome. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome. | 195 | P91938 | 596 | TRXR1_DROME Thioredoxin reductase 1, mitochon... | 479 | 5e-42 | 162 | 29 | 49 | GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005739; C:mitochondrion; IDA:UniProtKB. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IMP:FlyBase.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:FlyBase.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:UniProtKB. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IMP:UniProtKB.::GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0001666; P:response to hypoxia; IMP:FlyBase. | 196 | O62768 | 499 | TRXR1_BOVIN Thioredoxin reductase 1, cytoplas... | 433 | 5e-42 | 161 | 29 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 197 | Q5NVA2 | 499 | TRXR1_PONAB Thioredoxin reductase 1, cytoplas... | 460 | 2e-41 | 159 | 28 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 198 | Q9JMH6 | 613 | TRXR1_MOUSE Thioredoxin reductase 1, cytoplas... | 435 | 2e-41 | 160 | 29 | 50 | GO:0005829; C:cytosol; IDA:MGI.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:MGI. | | | | | | | | | | GO:0008283; P:cell proliferation; IMP:MGI.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0001707; P:mesoderm formation; IMP:MGI. | 199 | O89049 | 499 | TRXR1_RAT Thioredoxin reductase 1, cytoplasmi... | 434 | 2e-41 | 159 | 29 | 50 | GO:0005829; C:cytosol; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0045340; F:mercury ion binding; IDA:RGD.::GO:0016174; F:NAD(P)H oxidase activity; IDA:RGD.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0033797; F:selenate reductase activity; IDA:RGD.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:RGD. | | | | | | | | | | GO:0042537; P:benzene-containing compound metabolic process; IDA:RGD.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0071280; P:cellular response to copper ion; IEP:RGD.::GO:0071455; P:cellular response to hyperoxia; IEP:RGD.::GO:0006749; P:glutathione metabolic process; IEP:RGD.::GO:0070276; P:halogen metabolic process; IEP:RGD.::GO:0042744; P:hydrogen peroxide catabolic process; IMP:RGD.::GO:0042191; P:methylmercury metabolic process; IEP:RGD.::GO:0070995; P:NADPH oxidation; IDA:RGD.::GO:0001890; P:placenta development; IEP:RGD.::GO:0010942; P:positive regulation of cell death; IMP:RGD.::GO:0051262; P:protein tetramerization; IDA:RGD.::GO:0048678; P:response to axon injury; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0010269; P:response to selenium ion; IEP:RGD.::GO:0016259; P:selenocysteine metabolic process; IMP:RGD. | 200 | Q16881 | 649 | TRXR1_HUMAN Thioredoxin reductase 1, cytoplas... | 460 | 7e-41 | 159 | 28 | 48 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; EXP:Reactome. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.::GO:0007165; P:signal transduction; NAS:ProtInc.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 201 | Q6FRV2 | 476 | GSHR_CANGA Glutathione reductase OS=NRRL Y-65... | 477 | 1e-40 | 157 | 27 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro. | 202 | Q873E8 | 468 | GSHR_NEUCR Glutathione reductase OS=1257 / FG... | 467 | 3e-40 | 155 | 29 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro. | 203 | B9A1H3 | 495 | TRXR1_EMIHU Thioredoxin reductase SEP1 OS=Emi... | 482 | 5e-40 | 155 | 29 | 46 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 204 | P41921 | 483 | GSHR_YEAST Glutathione reductase OS=Saccharom... | 472 | 5e-40 | 155 | 27 | 49 | GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IDA:SGD.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0034599; P:cellular response to oxidative stress; IMP:SGD.::GO:0006749; P:glutathione metabolic process; IEA:InterPro.::GO:0010731; P:protein glutathionylation; IGI:SGD. | 205 | Q9MYY8 | 499 | TRXR1_PIG Thioredoxin reductase 1, cytoplasmi... | 438 | 5e-40 | 155 | 28 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:EC. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 206 | Q9N2I8 | 511 | TRXR2_BOVIN Thioredoxin reductase 2, mitochon... | 470 | 3e-39 | 153 | 28 | 46 | GO:0005739; C:mitochondrion; IDA:UniProtKB. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:UniProtKB. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0000305; P:response to oxygen radical; TAS:UniProtKB. | 207 | P13110 | 492 | TYTR_TRYCO Trypanothione reductase OS=Trypano... | 473 | 7e-39 | 152 | 29 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015042; F:trypanothione-disulfide reductase activity; IEA:EC. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. | 208 | Q6C5H4 | 470 | GSHR_YARLI Glutathione reductase OS=lipolytic... | 471 | 8e-39 | 151 | 30 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro. | 209 | Q8T137 | 465 | GSHR_DICDI Glutathione reductase OS=Dictyoste... | 433 | 1e-38 | 150 | 29 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IDA:dictyBase. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0043295; F:glutathione binding; IDA:dictyBase.::GO:0004362; F:glutathione-disulfide reductase activity; IMP:dictyBase.::GO:0050661; F:NADP binding; IDA:dictyBase. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IMP:dictyBase.::GO:0031154; P:culmination involved in sorocarp development; IMP:dictyBase.::GO:0006749; P:glutathione metabolic process; IMP:dictyBase. | 210 | O53355 | 493 | LPDA_MYCTU NAD(P)H dehydrogenase (quinone) OS... | 465 | 2e-38 | 151 | 27 | 47 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0050660; F:flavin adenine dinucleotide binding; IDA:MTBBASE.::GO:0003955; F:NAD(P)H dehydrogenase (quinone) activity; IDA:MTBBASE.::GO:0070401; F:NADP+ binding; IDA:MTBBASE. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0009405; P:pathogenesis; IMP:MTBBASE.::GO:0051289; P:protein homotetramerization; IPI:MTBBASE. | 211 | P39040 | 491 | TYTR_CRIFA Trypanothione reductase OS=Crithid... | 473 | 5e-38 | 149 | 27 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015042; F:trypanothione-disulfide reductase activity; IEA:EC. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro. |
