rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | P42345 | 2549 | MTOR_HUMAN Serine/threonine-protein kinase mT... | 135 | 2.5 | 36.2 | 26 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0005942; C:phosphatidylinositol 3-kinase complex; NAS:UniProtKB.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0031931; C:TORC1 complex; IDA:UniProtKB.::GO:0031932; C:TORC2 complex; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051219; F:phosphoprotein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0001030; F:RNA polymerase III type 1 promoter DNA binding; IDA:UniProtKB.::GO:0001031; F:RNA polymerase III type 2 promoter DNA binding; IDA:UniProtKB.::GO:0001032; F:RNA polymerase III type 3 promoter DNA binding; IDA:UniProtKB.::GO:0001156; F:TFIIIC-class transcription factor binding; IDA:UniProtKB. | | | | | | | | | | GO:0016049; P:cell growth; IDA:UniProtKB.::GO:0071456; P:cellular response to hypoxia; ISS:UniProtKB.::GO:0031669; P:cellular response to nutrient levels; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0046889; P:positive regulation of lipid biosynthetic process; IMP:UniProtKB.::GO:0045945; P:positive regulation of transcription from RNA polymerase III promoter; IMP:UniProtKB.::GO:0045727; P:positive regulation of translation; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0030163; P:protein catabolic process; TAS:UniProtKB.::GO:0043200; P:response to amino acid stimulus; IDA:UniProtKB.::GO:0007584; P:response to nutrient; NAS:UniProtKB.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0031929; P:TOR signaling cascade; IMP:UniProtKB. | 32 | Q92973 | 898 | TNPO1_HUMAN Transportin-1 OS=Homo sapiens (Hu... | 319 | 2.6 | 35.8 | 21 | 36 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; TAS:ProtInc. | | | | | | | | | | GO:0008139; F:nuclear localization sequence binding; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0010467; P:gene expression; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0000060; P:protein import into nucleus, translocation; TAS:ProtInc. | 33 | Q3SYU7 | 898 | TNPO1_BOVIN Transportin-1 OS=Bos taurus (Bovi... | 319 | 2.6 | 35.8 | 21 | 36 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 34 | Q92616 | 2671 | GCN1L_HUMAN Translational activator GCN1 OS=H... | 277 | 3.1 | 35.8 | 22 | 43 | GO:0005840; C:ribosome; NAS:UniProtKB. | | | | | | | | | | GO:0008135; F:translation factor activity, nucleic acid binding; NAS:UniProtKB. | | | | | | | | | | GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. | 35 | Q43052 | 710 | PAL2_POPKI Phenylalanine ammonia-lyase G2B OS... | 163 | 3.2 | 35.4 | 25 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0045548; F:phenylalanine ammonia-lyase activity; IEA:EC. | | | | | | | | | | GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0006559; P:L-phenylalanine catabolic process; IEA:InterPro.::GO:0009698; P:phenylpropanoid metabolic process; IEA:UniProtKB-KW. | 36 | C1JZ66 | 522 | IMA8_BOVIN Importin subunit alpha-8 OS=Bos ta... | 157 | 3.3 | 35.4 | 24 | 43 | GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006606; P:protein import into nucleus; IEA:InterPro. | 37 | Q8BFY9 | 898 | TNPO1_MOUSE Transportin-1 OS=Mus musculus (Mo... | 244 | 3.7 | 35.4 | 20 | 36 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 38 | O18388 | 884 | IMB_DROME Importin subunit beta OS=Drosophila... | 181 | 3.9 | 35.4 | 23 | 42 | GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005643; C:nuclear pore; ISS:FlyBase. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0008320; F:protein transmembrane transporter activity; ISS:FlyBase. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:FlyBase.::GO:0007304; P:chorion-containing eggshell formation; IMP:FlyBase.::GO:0007067; P:mitosis; IMP:FlyBase.::GO:0006607; P:NLS-bearing substrate import into nucleus; IDA:FlyBase.::GO:0051533; P:positive regulation of NFAT protein import into nucleus; IMP:FlyBase.::GO:0000059; P:protein import into nucleus, docking; IDA:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase. | 39 | Q91YE6 | 1041 | IPO9_MOUSE Importin-9 OS=Mus musculus (Mouse)... | 105 | 4.3 | 35 | 27 | 49 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; ISS:UniProtKB. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 40 | O14356 | 2335 | TOR1_SCHPO Phosphatidylinositol 3-kinase tor1... | 254 | 4.4 | 35.4 | 21 | 42 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0031932; C:TORC2 complex; IDA:PomBase. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; TAS:PomBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007569; P:cell aging; TAS:PomBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071470; P:cellular response to osmotic stress; IMP:PomBase.::GO:0031142; P:induction of conjugation upon nitrogen starvation; IMP:PomBase.::GO:0043091; P:L-arginine import; IMP:PomBase.::GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:PomBase.::GO:0060357; P:regulation of leucine import; IMP:PomBase.::GO:0009266; P:response to temperature stimulus; IMP:PomBase.::GO:0031929; P:TOR signaling cascade; TAS:PomBase. | 41 | Q96P70 | 1041 | IPO9_HUMAN Importin-9 OS=Homo sapiens (Human)... | 105 | 4.4 | 35 | 27 | 49 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0008565; F:protein transporter activity; IDA:UniProtKB. | | | | | | | | | | GO:0006606; P:protein import into nucleus; NAS:UniProtKB. | 42 | Q76P29 | 516 | IMAB_DICDI Importin subunit alpha-B OS=Dictyo... | 139 | 5.7 | 34.7 | 24 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005635; C:nuclear envelope; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006606; P:protein import into nucleus; IEA:InterPro. | 43 | P08032 | 2415 | SPTA1_MOUSE Spectrin alpha chain, erythrocyte... | 92 | 5.9 | 34.7 | 29 | 53 | GO:0032437; C:cuticular plate; IDA:MGI.::GO:0016020; C:membrane; IDA:MGI.::GO:0008091; C:spectrin; IMP:MGI.::GO:0014731; C:spectrin-associated cytoskeleton; IMP:MGI. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0046982; F:protein heterodimerization activity; IPI:MGI. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IMP:MGI.::GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.::GO:0030097; P:hemopoiesis; IMP:MGI.::GO:0002260; P:lymphocyte homeostasis; IMP:MGI.::GO:0007009; P:plasma membrane organization; IMP:MGI.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IMP:MGI.::GO:0042102; P:positive regulation of T cell proliferation; IMP:MGI.::GO:0008360; P:regulation of cell shape; IMP:MGI. | 44 | P51111 | 3110 | HD_RAT Huntingtin OS=Rattus norvegicus (Rat).... | 204 | 7.7 | 34.3 | 21 | 42 | GO:0005634; C:nucleus; IBA:RefGenome.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | | 45 | P39968 | 578 | VAC8_YEAST Vacuolar protein 8 OS=Saccharomyce... | 160 | 8.7 | 33.9 | 24 | 44 | GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0071563; C:Myo2p-Vac17p-Vac8p transport complex; IDA:SGD.::GO:0071561; C:nucleus-vacuole junction; IDA:SGD. | | | | | | | | | | GO:0043495; F:protein anchor; IMP:SGD. | | | | | | | | | | GO:0071255; P:CVT vesicle assembly; IMP:SGD.::GO:0016236; P:macroautophagy; IMP:SGD.::GO:0071562; P:nucleus-vacuole junction assembly; IMP:SGD.::GO:0042144; P:vacuole fusion, non-autophagic; IMP:SGD.::GO:0000011; P:vacuole inheritance; IMP:SGD. |