| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q5RGL7 | 434 | SMY2B_DANRE N-lysine methyltransferase SMYD2-... | 104 | 0.000000006 | 61.6 | 38 | 52 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0046975; F:histone methyltransferase activity (H3-K36 specific); ISS:UniProtKB.::GO:0000993; F:RNA polymerase II core binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0018027; P:peptidyl-lysine dimethylation; ISS:UniProtKB.::GO:0018026; P:peptidyl-lysine monomethylation; ISS:UniProtKB.::GO:0043516; P:regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 2 | O74467 | 319 | SET5_SCHPO SET domain-containing protein 5 OS... | 280 | 0.00000001 | 60.1 | 23 | 43 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; TAS:PomBase. | | | | | | | | | | | 3 | E1C5V0 | 436 | SMYD2_CHICK N-lysine methyltransferase SMYD2 ... | 187 | 0.00000008 | 57.8 | 27 | 45 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0046975; F:histone methyltransferase activity (H3-K36 specific); ISS:UniProtKB.::GO:0000993; F:RNA polymerase II core binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0018027; P:peptidyl-lysine dimethylation; ISS:UniProtKB.::GO:0018026; P:peptidyl-lysine monomethylation; ISS:UniProtKB.::GO:0043516; P:regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 4 | Q9NRG4 | 433 | SMYD2_HUMAN N-lysine methyltransferase SMYD2 ... | 185 | 0.0000001 | 57.4 | 27 | 46 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0046975; F:histone methyltransferase activity (H3-K36 specific); ISS:UniProtKB.::GO:0002039; F:p53 binding; IPI:UniProtKB.::GO:0000993; F:RNA polymerase II core binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0018027; P:peptidyl-lysine dimethylation; ISS:UniProtKB.::GO:0018026; P:peptidyl-lysine monomethylation; IDA:UniProtKB.::GO:0043516; P:regulation of DNA damage response, signal transduction by p53 class mediator; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 5 | Q9H7B4 | 428 | SMYD3_HUMAN SET and MYND domain-containing pr... | 118 | 0.0000001 | 57.4 | 30 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 6 | Q0P585 | 433 | SMYD2_BOVIN N-lysine methyltransferase SMYD2 ... | 185 | 0.0000002 | 56.6 | 29 | 46 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0046975; F:histone methyltransferase activity (H3-K36 specific); ISS:UniProtKB.::GO:0000993; F:RNA polymerase II core binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0018027; P:peptidyl-lysine dimethylation; ISS:UniProtKB.::GO:0018026; P:peptidyl-lysine monomethylation; ISS:UniProtKB.::GO:0043516; P:regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 7 | Q7M6Z3 | 433 | SMYD2_RAT N-lysine methyltransferase SMYD2 OS... | 185 | 0.0000003 | 56.2 | 29 | 46 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0046975; F:histone methyltransferase activity (H3-K36 specific); ISS:UniProtKB.::GO:0000993; F:RNA polymerase II core binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0018027; P:peptidyl-lysine dimethylation; ISS:UniProtKB.::GO:0018026; P:peptidyl-lysine monomethylation; ISS:UniProtKB.::GO:0043516; P:regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 8 | C3RZA1 | 433 | SMYD2_PIG N-lysine methyltransferase SMYD2 OS... | 185 | 0.0000003 | 55.8 | 29 | 46 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0046975; F:histone methyltransferase activity (H3-K36 specific); ISS:UniProtKB.::GO:0000993; F:RNA polymerase II core binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0018027; P:peptidyl-lysine dimethylation; ISS:UniProtKB.::GO:0018026; P:peptidyl-lysine monomethylation; ISS:UniProtKB.::GO:0043516; P:regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 9 | Q8R5A0 | 433 | SMYD2_MOUSE N-lysine methyltransferase SMYD2 ... | 153 | 0.0000003 | 55.8 | 30 | 48 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0046975; F:histone methyltransferase activity (H3-K36 specific); IDA:UniProtKB.::GO:0000993; F:RNA polymerase II core binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0018027; P:peptidyl-lysine dimethylation; IDA:UniProtKB.::GO:0018026; P:peptidyl-lysine monomethylation; ISS:UniProtKB.::GO:0043516; P:regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 10 | Q5BJI7 | 435 | SMY2A_DANRE N-lysine methyltransferase SMYD2-... | 137 | 0.0000004 | 55.8 | 29 | 50 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0046975; F:histone methyltransferase activity (H3-K36 specific); ISS:UniProtKB.::GO:0000993; F:RNA polymerase II core binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0018027; P:peptidyl-lysine dimethylation; ISS:UniProtKB.::GO:0018026; P:peptidyl-lysine monomethylation; ISS:UniProtKB.::GO:0043516; P:regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 11 | Q9CWR2 | 428 | SMYD3_MOUSE SET and MYND domain-containing pr... | 192 | 0.0000006 | 55.1 | 25 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 12 | Q6CX91 | 492 | SET5_KLULA Potential protein lysine methyltra... | 89 | 0.0000009 | 54.7 | 40 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 13 | Q54DL6 | 521 | Y2140_DICDI SET and MYND domain-containing pr... | 78 | 0.000002 | 53.5 | 37 | 55 | | | | | | | | | | | GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 14 | Q6GN68 | 430 | SMY2B_XENLA N-lysine methyltransferase SMYD2-... | 200 | 0.000003 | 53.1 | 27 | 44 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0046975; F:histone methyltransferase activity (H3-K36 specific); ISS:UniProtKB.::GO:0000993; F:RNA polymerase II core binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0018027; P:peptidyl-lysine dimethylation; ISS:UniProtKB.::GO:0018026; P:peptidyl-lysine monomethylation; ISS:UniProtKB.::GO:0043516; P:regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 15 | Q7ZXV5 | 430 | SMY2A_XENLA N-lysine methyltransferase SMYD2-... | 172 | 0.000003 | 53.1 | 27 | 48 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0046975; F:histone methyltransferase activity (H3-K36 specific); ISS:UniProtKB.::GO:0000993; F:RNA polymerase II core binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0018027; P:peptidyl-lysine dimethylation; ISS:UniProtKB.::GO:0018026; P:peptidyl-lysine monomethylation; ISS:UniProtKB.::GO:0043516; P:regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 16 | O94256 | 483 | SET6_SCHPO SET domain and MYND-type zinc fing... | 100 | 0.000003 | 53.1 | 30 | 53 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016571; P:histone methylation; IC:PomBase. | 17 | Q3TYX3 | 416 | SMYD5_MOUSE SET and MYND domain-containing pr... | 57 | 1.9 | 34.7 | 39 | 49 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 18 | Q54D67 | 343 | Y2454_DICDI SET and MYND domain-containing pr... | 74 | 0.000004 | 52.4 | 41 | 54 | | | | | | | | | | | GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 19 | Q6FTT0 | 515 | SET5_CANGA Potential protein lysine methyltra... | 74 | 0.000004 | 52.8 | 43 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 20 | A5DQN2 | 483 | SET5_PICGU Potential protein lysine methyltra... | 109 | 0.4 | 36.6 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 21 | Q75BF1 | 488 | SET5_ASHGO Potential protein lysine methyltra... | 82 | 0.000006 | 52 | 34 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 22 | P97443 | 490 | SMYD1_MOUSE SET and MYND domain-containing pr... | 111 | 0.000006 | 52 | 29 | 50 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0003714; F:transcription corepressor activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006338; P:chromatin remodeling; IPI:MGI.::GO:0007507; P:heart development; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 23 | P0CR43 | 449 | SET5_CRYNB Potential protein lysine methyltra... | 65 | 1.2 | 35 | 34 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 24 | P0CR42 | 449 | SET5_CRYNJ Potential protein lysine methyltra... | 65 | 1.2 | 35 | 34 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 25 | Q6GMV2 | 418 | SMYD5_HUMAN SET and MYND domain-containing pr... | 123 | 0.00001 | 50.8 | 30 | 47 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 26 | Q8NB12 | 490 | SMYD1_HUMAN SET and MYND domain-containing pr... | 111 | 0.00002 | 50.8 | 28 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 27 | Q54ZX8 | 549 | Y7331_DICDI SET and MYND domain-containing pr... | 79 | 0.00002 | 50.8 | 34 | 52 | | | | | | | | | | | GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 28 | Q6GPQ4 | 421 | SMYD5_XENLA SET and MYND domain-containing pr... | 61 | 0.42 | 36.6 | 34 | 54 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 29 | Q6C9E7 | 438 | SET5_YARLI Potential protein lysine methyltra... | 74 | 0.00007 | 48.5 | 35 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 30 | Q9ZUM9 | 398 | ASHR2_ARATH Histone-lysine N-methyltransferas... | 97 | 0.0001 | 47.8 | 29 | 47 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC. | | | | | | | | | | | 31 | Q5PP37 | 473 | ATXR2_ARATH Histone-lysine N-methyltransferas... | 75 | 0.0002 | 47.4 | 32 | 53 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | |
