| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | P42684 | 1182 | ABL2_HUMAN Abelson tyrosine-protein kinase 2 ... | 168 | 0.5 | 37.7 | 23 | 40 | GO:0015629; C:actin cytoskeleton; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0051015; F:actin filament binding; TAS:UniProtKB.::GO:0003785; F:actin monomer binding; TAS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0030145; F:manganese ion binding; IDA:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.::GO:0051353; P:positive regulation of oxidoreductase activity; IDA:BHF-UCL.::GO:2000249; P:regulation of actin cytoskeleton reorganization; TAS:UniProtKB.::GO:0010506; P:regulation of autophagy; TAS:UniProtKB.::GO:0030155; P:regulation of cell adhesion; TAS:UniProtKB.::GO:2000145; P:regulation of cell motility; TAS:UniProtKB.::GO:0030100; P:regulation of endocytosis; TAS:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc. | 32 | Q04736 | 541 | YES_MOUSE Tyrosine-protein kinase Yes OS=Mus ... | 160 | 0.53 | 37.4 | 24 | 38 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0015758; P:glucose transport; IDA:MGI. | 33 | P13115 | 532 | SRC1_XENLA Tyrosine-protein kinase Src-1 OS=X... | 156 | 0.54 | 37.4 | 23 | 38 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 34 | O19004 | 606 | ARAF_PIG Serine/threonine-protein kinase A-Ra... | 103 | 0.57 | 37.4 | 27 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 35 | Q66H50 | 515 | FACR1_RAT Fatty acyl-CoA reductase 1 OS=Rattu... | 99 | 0.58 | 37.4 | 32 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:EC. | | | | | | | | | | GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW. | 36 | Q8MVR1 | 2631 | GBPC_DICDI Cyclic GMP-binding protein C OS=Di... | 114 | 0.6 | 37.4 | 31 | 43 | GO:0005737; C:cytoplasm; IDA:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030553; F:cGMP binding; IDA:dictyBase.::GO:0005525; F:GTP binding; IDA:dictyBase.::GO:0005543; F:phospholipid binding; IDA:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; IDA:dictyBase. | | | | | | | | | | GO:0031589; P:cell-substrate adhesion; IMP:dictyBase.::GO:0019934; P:cGMP-mediated signaling; IDA:dictyBase.::GO:0007163; P:establishment or maintenance of cell polarity; IMP:dictyBase.::GO:0051272; P:positive regulation of cellular component movement; TAS:dictyBase.::GO:0045860; P:positive regulation of protein kinase activity; IMP:dictyBase.::GO:0046579; P:positive regulation of Ras protein signal transduction; IDA:dictyBase.::GO:0050920; P:regulation of chemotaxis; IMP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 37 | Q00944 | 1053 | FAK1_CHICK Focal adhesion kinase 1 OS=Gallus ... | 228 | 0.74 | 37 | 22 | 38 | GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0007172; P:signal complex assembly; IEA:InterPro. | 38 | F1LM93 | 541 | YES_RAT Tyrosine-protein kinase Yes OS=Rattus... | 160 | 0.76 | 37 | 24 | 38 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005154; F:epidermal growth factor receptor binding; IPI:RGD.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; IDA:RGD. | 39 | P27447 | 544 | YES_XIPHE Tyrosine-protein kinase Yes OS=Xiph... | 156 | 0.79 | 36.6 | 23 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 40 | P07947 | 543 | YES_HUMAN Tyrosine-protein kinase Yes OS=Homo... | 160 | 0.81 | 36.6 | 24 | 38 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0044325; F:ion channel binding; IPI:BHF-UCL.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:BHF-UCL. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0043114; P:regulation of vascular permeability; TAS:BHF-UCL.::GO:0031295; P:T cell costimulation; TAS:Reactome. | 41 | Q15375 | 998 | EPHA7_HUMAN Ephrin type-A receptor 7 OS=Homo ... | 105 | 0.86 | 37 | 26 | 50 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008046; F:axon guidance receptor activity; ISS:UniProtKB.::GO:0045499; F:chemorepellent activity; ISS:UniProtKB.::GO:0005004; F:GPI-linked ephrin receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007420; P:brain development; ISS:UniProtKB.::GO:0048755; P:branching morphogenesis of a nerve; ISS:UniProtKB.::GO:0043525; P:positive regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0022407; P:regulation of cell-cell adhesion; ISS:UniProtKB.::GO:0043281; P:regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0070372; P:regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.::GO:0050730; P:regulation of peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0031952; P:regulation of protein autophosphorylation; ISS:UniProtKB. | 42 | P14085 | 557 | SRC_AVIST Tyrosine-protein kinase transformin... | 159 | 0.92 | 36.6 | 23 | 38 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 43 | A7KAL2 | 960 | ATG1_PENCW Serine/threonine-protein kinase AT... | 325 | 0.98 | 36.6 | 24 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 44 | Q5ZM72 | 515 | FACR1_CHICK Fatty acyl-CoA reductase 1 OS=Gal... | 72 | 1.1 | 36.2 | 35 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:EC. | | | | | | | | | | GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW. | 45 | Q02977 | 536 | YRK_CHICK Proto-oncogene tyrosine-protein kin... | 157 | 1.1 | 36.2 | 20 | 39 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 46 | Q61772 | 998 | EPHA7_MOUSE Ephrin type-A receptor 7 OS=Mus m... | 105 | 1.2 | 36.6 | 26 | 50 | GO:0005887; C:integral to plasma membrane; IC:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008046; F:axon guidance receptor activity; IMP:UniProtKB.::GO:0045499; F:chemorepellent activity; IDA:MGI.::GO:0005004; F:GPI-linked ephrin receptor activity; IDA:UniProtKB. | | | | | | | | | | GO:0007420; P:brain development; IMP:UniProtKB.::GO:0048755; P:branching morphogenesis of a nerve; IMP:MGI.::GO:0043525; P:positive regulation of neuron apoptotic process; IMP:MGI.::GO:0022407; P:regulation of cell-cell adhesion; IDA:UniProtKB.::GO:0043281; P:regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.::GO:0070372; P:regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0050730; P:regulation of peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0031952; P:regulation of protein autophosphorylation; IDA:UniProtKB.::GO:0031290; P:retinal ganglion cell axon guidance; IMP:MGI. | 47 | O64771 | 809 | Y1148_ARATH G-type lectin S-receptor-like ser... | 184 | 1.2 | 36.2 | 23 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0044459; C:plasma membrane part; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0048544; P:recognition of pollen; IEA:InterPro. | 48 | Q5R834 | 515 | FACR1_PONAB Fatty acyl-CoA reductase 1 OS=Pon... | 79 | 1.2 | 36.2 | 35 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:EC. | | | | | | | | | | GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW. | 49 | Q8WVX9 | 515 | FACR1_HUMAN Fatty acyl-CoA reductase 1 OS=Hom... | 79 | 1.2 | 36.2 | 35 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005782; C:peroxisomal matrix; TAS:Reactome.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008611; P:ether lipid biosynthetic process; TAS:Reactome. | 50 | P14084 | 568 | SRC_AVISS Tyrosine-protein kinase transformin... | 156 | 1.3 | 36.2 | 22 | 38 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 51 | P05625 | 647 | RAF1_CHICK RAF proto-oncogene serine/threonin... | 151 | 1.3 | 36.2 | 23 | 42 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 52 | P00531 | 380 | MIL_AVIMH Serine/threonine-protein kinase-tra... | 146 | 1.3 | 35.8 | 23 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 53 | Q9FFW5 | 681 | PERK8_ARATH Proline-rich receptor-like protei... | 156 | 1.4 | 36.2 | 22 | 38 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005199; F:structural constituent of cell wall; IEA:InterPro. | | | | | | | | | | | 54 | Q922J9 | 515 | FACR1_MOUSE Fatty acyl-CoA reductase 1 OS=Mus... | 79 | 1.4 | 35.8 | 35 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050062; F:long-chain-fatty-acyl-CoA reductase activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0010025; P:wax biosynthetic process; IDA:UniProtKB. | 55 | Q7ZXF5 | 515 | FACR1_XENLA Fatty acyl-CoA reductase 1 OS=Xen... | 79 | 1.5 | 35.8 | 33 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:EC. | | | | | | | | | | GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW. | 56 | Q91738 | 1068 | FAK1_XENLA Focal adhesion kinase 1 OS=Xenopus... | 228 | 1.5 | 36.2 | 21 | 38 | GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007172; P:signal complex assembly; IEA:InterPro. | 57 | O42422 | 993 | EPHA7_CHICK Ephrin type-A receptor 7 OS=Gallu... | 105 | 1.6 | 35.8 | 26 | 50 | GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008046; F:axon guidance receptor activity; ISS:UniProtKB.::GO:0005004; F:GPI-linked ephrin receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007420; P:brain development; ISS:UniProtKB.::GO:0022407; P:regulation of cell-cell adhesion; ISS:UniProtKB.::GO:0043281; P:regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0070372; P:regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0050730; P:regulation of peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0031952; P:regulation of protein autophosphorylation; ISS:UniProtKB. | 58 | P15054 | 587 | SRC_AVIS2 Tyrosine-protein kinase transformin... | 156 | 1.6 | 35.8 | 22 | 38 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 59 | P00523 | 533 | SRC_CHICK Proto-oncogene tyrosine-protein kin... | 156 | 1.7 | 35.8 | 22 | 38 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0020037; F:heme binding; ISS:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 60 | Q6XUX1 | 927 | DUSTY_MOUSE Dual serine/threonine and tyrosin... | 102 | 2 | 35.8 | 25 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 61 | P03949 | 1224 | ABL1_CAEEL Tyrosine-protein kinase abl-1 OS=C... | 177 | 2 | 35.8 | 23 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0019901; F:protein kinase binding; IPI:WormBase. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0000077; P:DNA damage checkpoint; IGI:WormBase.::GO:0043066; P:negative regulation of apoptotic process; IMP:WormBase.::GO:0030336; P:negative regulation of cell migration; IGI:WormBase.::GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; IMP:WormBase.::GO:0060101; P:negative regulation of phagocytosis, engulfment; IGI:WormBase.::GO:0010212; P:response to ionizing radiation; IMP:WormBase.::GO:0007283; P:spermatogenesis; IMP:WormBase. |
