| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | Q96QV1 | 700 | HHIP_HUMAN Hedgehog-interacting protein OS=Ho... | 64 | 0.037 | 41.2 | 36 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; ISS:BHF-UCL. | | | | | | | | | | GO:0097108; F:hedgehog family protein binding; IPI:BHF-UCL.::GO:0016901; F:oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor; IEA:InterPro.::GO:0048038; F:quinone binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.::GO:0045879; P:negative regulation of smoothened signaling pathway; ISS:BHF-UCL.::GO:0048705; P:skeletal system morphogenesis; ISS:BHF-UCL. | 62 | Q6GUQ1 | 293 | EGFL8_MOUSE Epidermal growth factor-like prot... | 28 | 0.041 | 40.4 | 54 | 64 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; NAS:UniProtKB. | | | | | | | | | | | 63 | A5A8Y8 | 295 | EGFL8_PIG Epidermal growth factor-like protei... | 33 | 0.05 | 40 | 45 | 52 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | | 64 | P25371 | 1049 | ADP1_YEAST Probable ATP-dependent permease OS... | 51 | 0.064 | 40.4 | 39 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro. | | | | | | | | | | GO:0006810; P:transport; IEA:UniProtKB-KW. | 65 | Q8CFM6 | 1431 | STAB2_RAT Stabilin-2 OS=Rattus norvegicus (Ra... | 74 | 0.067 | 40.4 | 35 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0009897; C:external side of plasma membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051636; F:Gram-negative bacterial cell surface binding; ISS:UniProtKB.::GO:0005540; F:hyaluronic acid binding; IDA:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:InterPro.::GO:0006897; P:endocytosis; IDA:UniProtKB. | 66 | Q91ZI0 | 3301 | CELR3_MOUSE Cadherin EGF LAG seven-pass G-typ... | 103 | 0.083 | 40 | 30 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007413; P:axonal fasciculation; IMP:MGI.::GO:0007156; P:homophilic cell adhesion; IEA:InterPro.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro. | 67 | P68827 | 527 | NAGPA_BOVIN N-acetylglucosamine-1-phosphodies... | 58 | 0.09 | 39.7 | 40 | 52 | GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003944; F:N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity; IEA:EC. | | | | | | | | | | | 68 | O57409 | 615 | DLLB_DANRE Delta-like protein B OS=Danio reri... | 64 | 2.9 | 35 | 38 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW. | 69 | Q02858 | 1122 | TIE2_MOUSE Angiopoietin-1 receptor OS=Mus mus... | 87 | 0.17 | 38.9 | 30 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IGI:MGI.::GO:0016337; P:cell-cell adhesion; IMP:MGI.::GO:0007160; P:cell-matrix adhesion; IMP:MGI.::GO:0001935; P:endothelial cell proliferation; IMP:UniProtKB.::GO:0060347; P:heart trabecula formation; IMP:UniProtKB.::GO:0030097; P:hemopoiesis; IMP:MGI.::GO:0016525; P:negative regulation of angiogenesis; ISS:UniProtKB.::GO:2000352; P:negative regulation of endothelial cell apoptotic process; IMP:UniProtKB.::GO:0001569; P:patterning of blood vessels; TAS:DFLAT.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0010595; P:positive regulation of endothelial cell migration; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0051894; P:positive regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IGI:MGI.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; ISS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; TAS:DFLAT.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0001936; P:regulation of endothelial cell proliferation; TAS:DFLAT.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; ISS:UniProtKB.::GO:0032526; P:response to retinoic acid; IDA:BHF-UCL.::GO:0002040; P:sprouting angiogenesis; ISS:UniProtKB.::GO:0034446; P:substrate adhesion-dependent cell spreading; ISS:UniProtKB.::GO:0048014; P:Tie receptor signaling pathway; ISS:UniProtKB.::GO:0001570; P:vasculogenesis; IMP:UniProtKB. | 70 | Q60841 | 3461 | RELN_MOUSE Reelin OS=Mus musculus (Mouse). GN... | 54 | 8.3 | 33.5 | 30 | 46 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0030425; C:dendrite; IDA:MGI.::GO:0005615; C:extracellular space; IDA:MGI.::GO:0005578; C:proteinaceous extracellular matrix; TAS:MGI. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW.::GO:0070326; F:very-low-density lipoprotein particle receptor binding; IPI:BHF-UCL. | | | | | | | | | | GO:0007411; P:axon guidance; IMP:MGI.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0021800; P:cerebral cortex tangential migration; IMP:MGI.::GO:0016358; P:dendrite development; IMP:MGI.::GO:0010001; P:glial cell differentiation; IMP:MGI.::GO:0021766; P:hippocampus development; IDA:BHF-UCL.::GO:0097114; P:N-methyl-D-aspartate receptor clustering; IMP:BHF-UCL.::GO:0001764; P:neuron migration; IMP:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI.::GO:2000969; P:positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; IDA:BHF-UCL.::GO:0061003; P:positive regulation of dendritic spine morphogenesis; IMP:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; IDA:BHF-UCL.::GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.::GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:BHF-UCL.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IDA:BHF-UCL.::GO:0045860; P:positive regulation of protein kinase activity; IDA:MGI.::GO:0051057; P:positive regulation of small GTPase mediated signal transduction; IDA:MGI.::GO:0090129; P:positive regulation of synapse maturation; IDA:BHF-UCL.::GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; IDA:BHF-UCL.::GO:0032008; P:positive regulation of TOR signaling cascade; IDA:BHF-UCL.::GO:0097107; P:postsynaptic density assembly; IC:BHF-UCL.::GO:0097119; P:postsynaptic density protein 95 clustering; IMP:BHF-UCL.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0097120; P:receptor localization to synapse; IMP:BHF-UCL.::GO:0038026; P:reelin-mediated signaling pathway; IDA:BHF-UCL.::GO:0048265; P:response to pain; IMP:MGI.::GO:0021511; P:spinal cord patterning; IMP:MGI.::GO:0021517; P:ventral spinal cord development; IEP:UniProtKB. | 71 | Q90Y54 | 1213 | JAG1B_DANRE Protein jagged-1b OS=Danio rerio ... | 51 | 0.13 | 39.3 | 39 | 51 | GO:0016021; C:integral to membrane; NAS:ZFIN. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0060351; P:cartilage development involved in endochondral bone morphogenesis; IMP:ZFIN.::GO:0009953; P:dorsal/ventral pattern formation; IMP:ZFIN.::GO:0060325; P:face morphogenesis; IMP:ZFIN.::GO:0001889; P:liver development; IGI:ZFIN.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW. | 72 | P58751 | 3462 | RELN_RAT Reelin OS=Rattus norvegicus (Rat). G... | 50 | 8.1 | 33.5 | 30 | 40 | GO:0030424; C:axon; IDA:RGD.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0005615; C:extracellular space; ISS:UniProtKB.::GO:0043204; C:perikaryon; IDA:RGD.::GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; ISS:UniProtKB.::GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007411; P:axon guidance; ISS:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0071549; P:cellular response to dexamethasone stimulus; IEP:RGD.::GO:0021800; P:cerebral cortex tangential migration; ISS:UniProtKB.::GO:0021542; P:dentate gyrus development; IMP:RGD.::GO:0010001; P:glial cell differentiation; ISS:UniProtKB.::GO:0021854; P:hypothalamus development; IEP:RGD.::GO:0007626; P:locomotory behavior; IMP:RGD.::GO:0007613; P:memory; IEP:RGD.::GO:0007494; P:midgut development; IEP:RGD.::GO:0001764; P:neuron migration; IMP:UniProtKB.::GO:0021769; P:orbitofrontal cortex development; IEP:RGD.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0045860; P:positive regulation of protein kinase activity; ISS:UniProtKB.::GO:0051057; P:positive regulation of small GTPase mediated signal transduction; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0043200; P:response to amino acid stimulus; IEP:RGD.::GO:0048678; P:response to axon injury; IEP:RGD.::GO:0051412; P:response to corticosterone stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0051602; P:response to electrical stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0070542; P:response to fatty acid; IEP:RGD.::GO:0017085; P:response to insecticide; IEP:RGD.::GO:0010226; P:response to lithium ion; IEP:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0048265; P:response to pain; ISS:UniProtKB.::GO:0032570; P:response to progesterone stimulus; IEP:RGD.::GO:0035176; P:social behavior; IEP:RGD.::GO:0021511; P:spinal cord patterning; ISS:UniProtKB. | 73 | Q6MG84 | 291 | EGFL8_RAT Epidermal growth factor-like protei... | 28 | 0.15 | 38.5 | 50 | 61 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | | 74 | B0WH58 | 658 | CUE_CULQU Protein cueball OS=Culex quinquefas... | 52 | 0.17 | 38.9 | 31 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0048477; P:oogenesis; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB. | 75 | Q9IAT6 | 664 | DLLC_DANRE Delta-like protein C OS=Danio reri... | 46 | 0.18 | 38.9 | 41 | 54 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IGI:ZFIN.::GO:0005886; C:plasma membrane; IDA:ZFIN. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0042802; F:identical protein binding; IDA:ZFIN.::GO:0030165; F:PDZ domain binding; IDA:ZFIN. | | | | | | | | | | GO:0048666; P:neuron development; IMP:ZFIN.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0001756; P:somitogenesis; IMP:ZFIN. | 76 | Q27591 | 799 | ITBN_DROME Integrin beta-nu OS=Drosophila mel... | 81 | 0.19 | 38.9 | 32 | 40 | GO:0008305; C:integrin complex; ISS:FlyBase. | | | | | | | | | | GO:0050839; F:cell adhesion molecule binding; TAS:FlyBase.::GO:0004872; F:receptor activity; TAS:FlyBase. | | | | | | | | | | GO:0007160; P:cell-matrix adhesion; TAS:FlyBase.::GO:0007157; P:heterophilic cell-cell adhesion; TAS:FlyBase.::GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:InterPro.::GO:0042048; P:olfactory behavior; IMP:FlyBase. | 77 | Q9R172 | 2319 | NOTC3_RAT Neurogenic locus notch homolog prot... | 65 | 0.24 | 38.5 | 40 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007219; P:Notch signaling pathway; IDA:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IDA:RGD.::GO:0042246; P:tissue regeneration; IEP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 78 | P10041 | 833 | DL_DROME Neurogenic locus protein delta OS=Dr... | 47 | 4 | 34.7 | 38 | 55 | GO:0005912; C:adherens junction; IDA:FlyBase.::GO:0009986; C:cell surface; IDA:FlyBase.::GO:0030139; C:endocytic vesicle; IDA:FlyBase.::GO:0016021; C:integral to membrane; NAS:FlyBase.::GO:0035003; C:subapical complex; IDA:FlyBase. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005112; F:Notch binding; IDA:FlyBase. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:FlyBase.::GO:0048800; P:antennal morphogenesis; IMP:FlyBase.::GO:0007475; P:apposition of dorsal and ventral imaginal disc-derived wing surfaces; IMP:FlyBase.::GO:0008356; P:asymmetric cell division; TAS:FlyBase.::GO:0007298; P:border follicle cell migration; IMP:FlyBase.::GO:0007155; P:cell adhesion; TAS:FlyBase.::GO:0001708; P:cell fate specification; TAS:FlyBase.::GO:0008407; P:chaeta morphogenesis; IMP:FlyBase.::GO:0042676; P:compound eye cone cell fate commitment; TAS:FlyBase.::GO:0046667; P:compound eye retinal cell programmed cell death; TAS:FlyBase.::GO:0007451; P:dorsal/ventral lineage restriction, imaginal disc; TAS:FlyBase.::GO:0007398; P:ectoderm development; TAS:FlyBase.::GO:0030718; P:germ-line stem cell maintenance; IMP:FlyBase.::GO:0008347; P:glial cell migration; IMP:FlyBase.::GO:0036011; P:imaginal disc-derived leg segmentation; IMP:FlyBase.::GO:0007474; P:imaginal disc-derived wing vein specification; NAS:FlyBase.::GO:0046331; P:lateral inhibition; IMP:FlyBase.::GO:0007498; P:mesoderm development; IMP:FlyBase.::GO:0035157; P:negative regulation of fusion cell fate specification; NAS:FlyBase.::GO:0050768; P:negative regulation of neurogenesis; IMP:FlyBase.::GO:0035155; P:negative regulation of terminal cell fate specification, open tracheal system; NAS:FlyBase.::GO:0007219; P:Notch signaling pathway; IMP:FlyBase.::GO:0016318; P:ommatidial rotation; NAS:FlyBase.::GO:0007314; P:oocyte anterior/posterior axis specification; TAS:FlyBase.::GO:0030720; P:oocyte localization involved in germarium-derived egg chamber formation; IMP:FlyBase.::GO:0007424; P:open tracheal system development; NAS:FlyBase.::GO:0030713; P:ovarian follicle cell stalk formation; IMP:FlyBase.::GO:0007422; P:peripheral nervous system development; IMP:FlyBase.::GO:0008284; P:positive regulation of cell proliferation; IMP:FlyBase.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:FlyBase.::GO:0007464; P:R3/R4 cell fate commitment; NAS:FlyBase.::GO:0007460; P:R8 cell fate commitment; TAS:FlyBase.::GO:0045468; P:regulation of R8 cell spacing in compound eye; NAS:FlyBase.::GO:0016330; P:second mitotic wave involved in compound eye morphogenesis; IMP:FlyBase.::GO:0007419; P:ventral cord development; NAS:FlyBase.::GO:0048190; P:wing disc dorsal/ventral pattern formation; IMP:FlyBase. | 79 | P80747 | 800 | ITB5_BOVIN Integrin beta-5 OS=Bos taurus (Bov... | 66 | 1.7 | 35.8 | 35 | 47 | GO:0008305; C:integrin complex; IEA:InterPro. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007160; P:cell-matrix adhesion; IEA:InterPro.::GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:InterPro. | 80 | Q8R508 | 4555 | FAT3_RAT Protocadherin Fat 3 OS=Rattus norveg... | 81 | 0.26 | 38.5 | 37 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:InterPro. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0007156; P:homophilic cell adhesion; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 81 | Q61982 | 2318 | NOTC3_MOUSE Neurogenic locus notch homolog pr... | 65 | 0.33 | 38.1 | 40 | 49 | GO:0005887; C:integral to plasma membrane; IC:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030900; P:forebrain development; IGI:MGI.::GO:0072104; P:glomerular capillary formation; IEP:UniProtKB.::GO:0045665; P:negative regulation of neuron differentiation; IMP:MGI.::GO:0048663; P:neuron fate commitment; IGI:MGI.::GO:0007219; P:Notch signaling pathway; IDA:UniProtKB.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 82 | B4MLE8 | 651 | CUE_DROWI Protein cueball OS=Drosophila willi... | 51 | 0.35 | 37.7 | 35 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0048477; P:oogenesis; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB. | 83 | Q8JZM4 | 737 | DNER_MOUSE Delta and Notch-like epidermal gro... | 68 | 0.35 | 37.7 | 38 | 49 | GO:0030425; C:dendrite; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005112; F:Notch binding; IPI:MGI.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010001; P:glial cell differentiation; IDA:MGI.::GO:0007220; P:Notch receptor processing; IDA:MGI.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0048741; P:skeletal muscle fiber development; IDA:MGI. | 84 | Q06805 | 1136 | TIE1_BOVIN Tyrosine-protein kinase receptor T... | 63 | 0.71 | 37 | 32 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW. | 85 | Q06806 | 1134 | TIE1_MOUSE Tyrosine-protein kinase receptor T... | 62 | 0.77 | 37 | 32 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0001701; P:in utero embryonic development; IGI:MGI.::GO:0016525; P:negative regulation of angiogenesis; IMP:MGI.::GO:0030336; P:negative regulation of cell migration; IMP:MGI.::GO:0045026; P:plasma membrane fusion; IMP:MGI.::GO:0032526; P:response to retinoic acid; IDA:BHF-UCL. | 86 | A0A1F4 | 2176 | EYS_DROME Protein eyes shut OS=Drosophila mel... | 32 | 0.41 | 37.7 | 41 | 56 | GO:0005615; C:extracellular space; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:FlyBase. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005201; F:extracellular matrix structural constituent; IMP:FlyBase.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0000902; P:cell morphogenesis; IMP:FlyBase.::GO:0042052; P:rhabdomere development; IMP:UniProtKB.::GO:0010378; P:temperature compensation of the circadian clock; IMP:FlyBase. | 87 | Q9NR61 | 685 | DLL4_HUMAN Delta-like protein 4 OS=Homo sapie... | 53 | 0.44 | 37.7 | 43 | 57 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005112; F:Notch binding; TAS:ProtInc. | | | | | | | | | | GO:0008015; P:blood circulation; TAS:ProtInc.::GO:0035912; P:dorsal aorta morphogenesis; ISS:BHF-UCL.::GO:0007220; P:Notch receptor processing; TAS:Reactome.::GO:0007219; P:Notch signaling pathway; TAS:Reactome. | 88 | Q06807 | 1125 | TIE2_BOVIN Angiopoietin-1 receptor OS=Bos tau... | 63 | 0.8 | 37 | 32 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0001935; P:endothelial cell proliferation; ISS:UniProtKB.::GO:0060347; P:heart trabecula formation; ISS:UniProtKB.::GO:0016525; P:negative regulation of angiogenesis; ISS:UniProtKB.::GO:2000352; P:negative regulation of endothelial cell apoptotic process; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0010595; P:positive regulation of endothelial cell migration; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0051894; P:positive regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; ISS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; ISS:UniProtKB.::GO:0002040; P:sprouting angiogenesis; ISS:UniProtKB.::GO:0034446; P:substrate adhesion-dependent cell spreading; ISS:UniProtKB.::GO:0048014; P:Tie receptor signaling pathway; ISS:UniProtKB. | 89 | Q70E20 | 1403 | SNED1_MOUSE Sushi, nidogen and EGF-like domai... | 88 | 0.47 | 37.7 | 33 | 42 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0007160; P:cell-matrix adhesion; IEA:InterPro. | 90 | Q64632 | 1807 | ITB4_RAT Integrin beta-4 OS=Rattus norvegicus... | 100 | 0.54 | 37.4 | 30 | 39 | GO:0005938; C:cell cortex; IDA:RGD.::GO:0031252; C:cell leading edge; ISS:UniProtKB.::GO:0005615; C:extracellular space; TAS:RGD.::GO:0030056; C:hemidesmosome; IEA:UniProtKB-SubCell.::GO:0008305; C:integrin complex; TAS:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0050839; F:cell adhesion molecule binding; TAS:RGD.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0048870; P:cell motility; ISS:UniProtKB.::GO:0007160; P:cell-matrix adhesion; IEA:InterPro.::GO:0007229; P:integrin-mediated signaling pathway; TAS:RGD.::GO:0007275; P:multicellular organismal development; IEA:InterPro.::GO:0009611; P:response to wounding; ISS:UniProtKB. | 91 | P35590 | 1138 | TIE1_HUMAN Tyrosine-protein kinase receptor T... | 63 | 0.64 | 37.4 | 32 | 41 | GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0007498; P:mesoderm development; TAS:ProtInc. |
