| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q7RVY5 | 629 | HEM1_NEUCR 5-aminolevulinate synthase, mitoch... | 90 | 3e-17 | 87.4 | 53 | 59 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 2 | P38092 | 648 | HEM1_EMENI 5-aminolevulinate synthase, mitoch... | 63 | 0.00000000001 | 70.1 | 51 | 63 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 3 | Q6CCW0 | 563 | HEM1_YARLI 5-aminolevulinate synthase, mitoch... | 58 | 0.000009 | 51.6 | 45 | 57 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 4 | O14092 | 558 | HEM1_SCHPO 5-aminolevulinate synthase, mitoch... | 196 | 5e-89 | 287 | 66 | 82 | GO:0005759; C:mitochondrial matrix; ISS:PomBase. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; ISS:PomBase.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; ISS:PomBase. | 5 | Q92403 | 621 | HEM1_AGABI 5-aminolevulinate synthase, mitoch... | 59 | 0.0004 | 46.2 | 37 | 53 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 6 | O94069 | 564 | HEM1_CANAL 5-aminolevulinate synthase, mitoch... | 62 | 1.8 | 34.7 | 32 | 48 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IMP:CGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IMP:CGD. | 7 | Q6BX71 | 575 | HEM1_DEBHA 5-aminolevulinate synthase, mitoch... | 62 | 0.0003 | 46.6 | 34 | 52 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 8 | Q75DX7 | 556 | HEM1_ASHGO 5-aminolevulinate synthase, mitoch... | 59 | 0.000008 | 51.6 | 39 | 56 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 9 | P78698 | 570 | HEM1_KLULA 5-aminolevulinate synthase, mitoch... | 59 | 0.0005 | 45.8 | 37 | 53 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 10 | P09950 | 548 | HEM1_YEAST 5-aminolevulinate synthase, mitoch... | 59 | 0.002 | 43.9 | 34 | 53 | GO:0005759; C:mitochondrial matrix; IDA:SGD. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IDA:SGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IMP:SGD. | 11 | Q6FXE3 | 530 | HEM1_CANGA 5-aminolevulinate synthase, mitoch... | 58 | 0.063 | 39.3 | 33 | 52 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 12 | P43091 | 627 | HEM1_OPSTA 5-aminolevulinate synthase, nonspe... | 201 | 4e-61 | 214 | 53 | 71 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 13 | P26505 | 405 | HEM1_RHIRD 5-aminolevulinate synthase OS=radi... | 194 | 1e-60 | 208 | 53 | 69 | | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 14 | P08080 | 404 | HEM1_RHIME 5-aminolevulinate synthase OS=meli... | 191 | 4e-59 | 204 | 55 | 70 | | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 15 | A6QLI6 | 647 | HEM1_BOVIN 5-aminolevulinate synthase, nonspe... | 240 | 7e-59 | 209 | 47 | 62 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 16 | P13195 | 642 | HEM1_RAT 5-aminolevulinate synthase, nonspeci... | 240 | 1e-58 | 208 | 47 | 62 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IDA:RGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0032869; P:cellular response to insulin stimulus; IEP:RGD.::GO:0071407; P:cellular response to organic cyclic compound; IEP:RGD.::GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0051591; P:response to cAMP; IEP:RGD.::GO:0032025; P:response to cobalt ion; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0034698; P:response to gonadotropin stimulus; IEP:RGD.::GO:0009635; P:response to herbicide; IEP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0010045; P:response to nickel cation; IEP:RGD.::GO:0031667; P:response to nutrient levels; IEP:RGD.::GO:0070541; P:response to platinum ion; IEP:RGD. | 17 | P43090 | 582 | HEM0_OPSTA 5-aminolevulinate synthase, erythr... | 199 | 1e-58 | 207 | 51 | 69 | GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0001666; P:response to hypoxia; ISS:UniProtKB. | 18 | Q8VC19 | 642 | HEM1_MOUSE 5-aminolevulinate synthase, nonspe... | 235 | 2e-58 | 207 | 48 | 63 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 19 | Q5R9R9 | 640 | HEM1_PONAB 5-aminolevulinate synthase, nonspe... | 235 | 1e-57 | 205 | 47 | 63 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 20 | P13196 | 640 | HEM1_HUMAN 5-aminolevulinate synthase, nonspe... | 235 | 1e-57 | 205 | 47 | 63 | GO:0005759; C:mitochondrial matrix; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0006783; P:heme biosynthetic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 21 | Q9YHT4 | 583 | HEM0_DANRE 5-aminolevulinate synthase, erythr... | 195 | 2e-57 | 204 | 52 | 70 | GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0035162; P:embryonic hemopoiesis; IMP:ZFIN.::GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0006783; P:heme biosynthetic process; ISS:UniProtKB.::GO:0042541; P:hemoglobin biosynthetic process; ISS:UniProtKB.::GO:0001666; P:response to hypoxia; ISS:UniProtKB. | 22 | P08680 | 587 | HEM0_MOUSE 5-aminolevulinate synthase, erythr... | 197 | 8e-57 | 202 | 51 | 68 | GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006879; P:cellular iron ion homeostasis; IMP:MGI.::GO:0030218; P:erythrocyte differentiation; IMP:UniProtKB.::GO:0006783; P:heme biosynthetic process; IMP:UniProtKB.::GO:0042541; P:hemoglobin biosynthetic process; IMP:UniProtKB.::GO:0001666; P:response to hypoxia; ISS:UniProtKB. | 23 | P22557 | 587 | HEM0_HUMAN 5-aminolevulinate synthase, erythr... | 197 | 1e-56 | 201 | 51 | 69 | GO:0005743; C:mitochondrial inner membrane; IDA:UniProtKB.::GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IDA:UniProtKB.::GO:0050662; F:coenzyme binding; ISS:UniProtKB.::GO:0016594; F:glycine binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006879; P:cellular iron ion homeostasis; ISS:UniProtKB.::GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0006783; P:heme biosynthetic process; ISS:UniProtKB.::GO:0042541; P:hemoglobin biosynthetic process; ISS:UniProtKB.::GO:0032364; P:oxygen homeostasis; NAS:UniProtKB.::GO:0001666; P:response to hypoxia; IDA:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 24 | Q9XT75 | 582 | HEM0_DELLE 5-aminolevulinate synthase, erythr... | 197 | 2e-56 | 201 | 52 | 68 | GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0006783; P:heme biosynthetic process; ISS:UniProtKB.::GO:0042541; P:hemoglobin biosynthetic process; ISS:UniProtKB.::GO:0001666; P:response to hypoxia; ISS:UniProtKB. | 25 | Q5R557 | 587 | HEM0_PONAB 5-aminolevulinate synthase, erythr... | 197 | 3e-56 | 200 | 51 | 69 | GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0001666; P:response to hypoxia; ISS:UniProtKB. | 26 | Q04512 | 407 | HEM1_RHOS4 5-aminolevulinate synthase 1 OS=15... | 225 | 6e-56 | 196 | 49 | 60 | | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 27 | Q63147 | 587 | HEM0_RAT 5-aminolevulinate synthase, erythroi... | 197 | 8e-56 | 199 | 51 | 68 | GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; ISS:UniProtKB.::GO:0050662; F:coenzyme binding; IDA:RGD.::GO:0016594; F:glycine binding; IDA:RGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0007565; P:female pregnancy; IEP:RGD.::GO:0006783; P:heme biosynthetic process; ISS:UniProtKB.::GO:0042541; P:hemoglobin biosynthetic process; ISS:UniProtKB.::GO:0007595; P:lactation; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0001666; P:response to hypoxia; ISS:UniProtKB.::GO:0010288; P:response to lead ion; IEP:RGD. | 28 | Q9XS79 | 640 | HEM1_DELLE 5-aminolevulinate synthase, nonspe... | 240 | 1e-55 | 199 | 45 | 61 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 29 | Q3ZC31 | 587 | HEM0_BOVIN 5-aminolevulinate synthase, erythr... | 197 | 3e-55 | 197 | 51 | 67 | GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0001666; P:response to hypoxia; ISS:UniProtKB. | 30 | P08262 | 409 | HEM1_BRAJA 5-aminolevulinate synthase OS=Brad... | 209 | 6e-55 | 193 | 48 | 64 | | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. | 31 | Q06965 | 407 | HEM0_RHOS4 5-aminolevulinate synthase 2 OS=15... | 194 | 3e-54 | 191 | 50 | 65 | | | | | | | | | | | GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro. | | | | | | | | | | GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW. |
