rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q96KN3 | 472 | PKNX2_HUMAN Homeobox protein PKNOX2 OS=Homo s... | 77 | 7e-18 | 89.7 | 49 | 69 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | | 2 | Q8BG99 | 474 | PKNX2_MOUSE Homeobox protein PKNOX2 OS=Mus mu... | 77 | 8e-18 | 89.7 | 49 | 69 | GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0015630; C:microtubule cytoskeleton; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:MGI.::GO:0003785; F:actin monomer binding; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IGI:MGI. | 3 | Q86IH1 | 740 | HBX4_DICDI Homeobox protein 4 OS=Dictyosteliu... | 140 | 8e-18 | 90.1 | 39 | 51 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 4 | Q5R6L1 | 472 | PKNX2_PONAB Homeobox protein PKNOX2 OS=Pongo ... | 77 | 1e-17 | 89 | 48 | 69 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | | 5 | Q2HJ84 | 436 | PKNX1_BOVIN Homeobox protein PKNOX1 OS=Bos ta... | 74 | 2e-17 | 88.2 | 47 | 72 | | | | | | | | | | | | | | | | | | | | | | 6 | O46339 | 487 | HTH_DROME Homeobox protein homothorax OS=Dros... | 69 | 2e-17 | 88.6 | 52 | 72 | GO:0005667; C:transcription factor complex; IDA:UniProtKB. | | | | | | | | | | GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:FlyBase.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0008134; F:transcription factor binding; IPI:FlyBase. | | | | | | | | | | GO:0007420; P:brain development; IMP:FlyBase.::GO:0001752; P:compound eye photoreceptor fate commitment; IMP:FlyBase.::GO:0048735; P:haltere morphogenesis; IMP:FlyBase.::GO:0007480; P:imaginal disc-derived leg morphogenesis; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0007479; P:leg disc proximal/distal pattern formation; TAS:FlyBase.::GO:0007422; P:peripheral nervous system development; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.::GO:0000060; P:protein import into nucleus, translocation; IMP:UniProtKB.::GO:0045664; P:regulation of neuron differentiation; IMP:FlyBase.::GO:0007432; P:salivary gland boundary specification; NAS:FlyBase.::GO:0010092; P:specification of organ identity; TAS:FlyBase.::GO:0007383; P:specification of segmental identity, antennal segment; IMP:FlyBase. | 7 | P55347 | 436 | PKNX1_HUMAN Homeobox protein PKNOX1 OS=Homo s... | 74 | 2e-17 | 87.8 | 47 | 72 | | | | | | | | | | | | | | | | | | | | | | 8 | O70477 | 436 | PKNX1_MOUSE Homeobox protein PKNOX1 OS=Mus mu... | 74 | 2e-17 | 87.8 | 47 | 72 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005667; C:transcription factor complex; IDA:MGI. | | | | | | | | | | GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:BHF-UCL. | | | | | | | | | | GO:0001525; P:angiogenesis; IMP:MGI.::GO:0043010; P:camera-type eye development; IMP:MGI.::GO:0030218; P:erythrocyte differentiation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0030217; P:T cell differentiation; IMP:MGI. | 9 | Q8C0Y1 | 237 | TGIF2_MOUSE Homeobox protein TGIF2 OS=Mus mus... | 81 | 1e-16 | 83.2 | 53 | 63 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0045666; P:positive regulation of neuron differentiation; IDA:MGI.::GO:0060041; P:retina development in camera-type eye; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 10 | A8K0S8 | 358 | ME3L2_HUMAN Putative homeobox protein Meis3-l... | 73 | 2e-16 | 84.3 | 47 | 74 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | | 11 | Q9GZN2 | 237 | TGIF2_HUMAN Homeobox protein TGIF2 OS=Homo sa... | 81 | 2e-16 | 82.8 | 53 | 63 | GO:0005634; C:nucleus; TAS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 12 | P41817 | 306 | CUP9_YEAST Homeobox protein CUP9 OS=Saccharom... | 100 | 2e-16 | 83.6 | 45 | 58 | GO:0005634; C:nucleus; IC:SGD. | | | | | | | | | | GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:SGD.::GO:0001133; F:sequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity; IC:SGD. | | | | | | | | | | GO:0035955; P:negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter; IMP:SGD. | 13 | Q99687 | 375 | MEIS3_HUMAN Homeobox protein Meis3 OS=Homo sa... | 73 | 3e-16 | 84 | 47 | 73 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | | 14 | A6NDR6 | 274 | ME3L1_HUMAN Putative homeobox protein Meis3-l... | 73 | 3e-16 | 82.4 | 47 | 73 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | | 15 | P97368 | 378 | MEIS3_MOUSE Homeobox protein Meis3 OS=Mus mus... | 100 | 4e-16 | 83.6 | 40 | 61 | GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro. | | | | | | | | | | GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:MGI. | 16 | Q8IUE1 | 241 | TF2LX_HUMAN Homeobox protein TGIF2LX OS=Homo ... | 92 | 7e-16 | 80.9 | 48 | 60 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 17 | Q6DIF3 | 453 | MEIS3_XENTR Homeobox protein meis3 OS=Xenopus... | 67 | 8e-16 | 83.2 | 49 | 72 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0009952; P:anterior/posterior pattern specification; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030902; P:hindbrain development; ISS:UniProtKB.::GO:0043410; P:positive regulation of MAPK cascade; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 18 | Q5U4X3 | 453 | MEI3A_XENLA Homeobox protein meis3-A OS=Xenop... | 67 | 9e-16 | 83.2 | 49 | 72 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0009952; P:anterior/posterior pattern specification; IMP:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030902; P:hindbrain development; IMP:UniProtKB.::GO:0043410; P:positive regulation of MAPK cascade; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 19 | Q7ZY13 | 451 | MEI3B_XENLA Homeobox protein meis3-B OS=Xenop... | 67 | 9e-16 | 83.2 | 49 | 72 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0009952; P:anterior/posterior pattern specification; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030902; P:hindbrain development; ISS:UniProtKB.::GO:0043410; P:positive regulation of MAPK cascade; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 20 | Q8MIB7 | 241 | TF2LX_PANTR Homeobox protein TGIF2LX OS=Pan t... | 92 | 0.000000000000001 | 80.5 | 48 | 60 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 21 | Q54VB4 | 639 | HBX9_DICDI Homeobox protein 9 OS=Dictyosteliu... | 70 | 0.000000000000001 | 83.2 | 53 | 61 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 22 | Q8IUE0 | 185 | TF2LY_HUMAN Homeobox protein TGIF2LY OS=Homo ... | 92 | 0.000000000000001 | 79.3 | 47 | 60 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 23 | Q90655 | 269 | AKR_CHICK Homeobox protein AKR OS=Gallus gall... | 66 | 0.000000000000002 | 80.1 | 56 | 67 | GO:0005634; C:nucleus; IC:Roslin. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 24 | Q8MIE9 | 241 | TF2LX_GORGO Homeobox protein TGIF2LX OS=Goril... | 85 | 0.000000000000002 | 79.3 | 47 | 60 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 25 | A1YGI6 | 241 | TF2LX_PANPA Homeobox protein TGIF2LX OS=Pan p... | 68 | 0.000000000000003 | 79 | 53 | 66 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 26 | P79937 | 390 | MEIS1_XENLA Homeobox protein Meis1 OS=Xenopus... | 68 | 0.000000000000005 | 80.5 | 49 | 71 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005667; C:transcription factor complex; IGI:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0014036; P:neural crest cell fate specification; IGI:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 27 | P70284 | 272 | TGIF1_MOUSE Homeobox protein TGIF1 OS=Mus mus... | 66 | 0.000000000000005 | 78.6 | 55 | 67 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0007368; P:determination of left/right symmetry; IMP:MGI.::GO:0009953; P:dorsal/ventral pattern formation; IMP:MGI.::GO:0008285; P:negative regulation of cell proliferation; IMP:MGI.::GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0001843; P:neural tube closure; IMP:MGI.::GO:0048146; P:positive regulation of fibroblast proliferation; IMP:MGI.::GO:0045666; P:positive regulation of neuron differentiation; IDA:MGI.::GO:0060041; P:retina development in camera-type eye; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 28 | P97367 | 477 | MEIS2_MOUSE Homeobox protein Meis2 OS=Mus mus... | 64 | 0.000000000000008 | 80.5 | 50 | 72 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0001654; P:eye development; IGI:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI. | 29 | O14770 | 477 | MEIS2_HUMAN Homeobox protein Meis2 OS=Homo sa... | 64 | 0.000000000000008 | 80.1 | 50 | 72 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc. | | | | | | | | | | GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc. | 30 | Q8SRR1 | 193 | HD12_ENCCU Homeobox protein HD-12 OS=Encephal... | 60 | 0.00000000000001 | 77 | 55 | 72 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | | 31 | Q60954 | 390 | MEIS1_MOUSE Homeobox protein Meis1 OS=Mus mus... | 64 | 0.00000000000001 | 79 | 50 | 72 | GO:0005634; C:nucleus; IDA:MGI.::GO:0005667; C:transcription factor complex; IDA:MGI. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003677; F:DNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.::GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IMP:MGI.::GO:0048514; P:blood vessel morphogenesis; IMP:MGI.::GO:0060216; P:definitive hemopoiesis; IMP:MGI.::GO:0030097; P:hemopoiesis; IMP:MGI.::GO:0002089; P:lens morphogenesis in camera-type eye; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |