| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | Q6KC51 | 612 | ABLM2_RAT Actin-binding LIM protein 2 OS=Ratt... | 93 | 0.007 | 43.9 | 23 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; IEA:InterPro. | 62 | Q3TJD7 | 457 | PDLI7_MOUSE PDZ and LIM domain protein 7 OS=M... | 117 | 0.0000001 | 59.3 | 29 | 47 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0001726; C:ruffle; IDA:MGI.::GO:0001725; C:stress fiber; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IPI:MGI.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0001503; P:ossification; IEA:UniProtKB-KW. | 63 | Q15311 | 655 | RBP1_HUMAN RalA-binding protein 1 OS=Homo sap... | 181 | 0.000000000001 | 75.5 | 30 | 52 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IDA:UniProtKB. | | | | | | | | | | GO:0043492; F:ATPase activity, coupled to movement of substances; IDA:UniProtKB.::GO:0030675; F:Rac GTPase activator activity; IDA:UniProtKB.::GO:0048365; F:Rac GTPase binding; IPI:UniProtKB.::GO:0017160; F:Ral GTPase binding; IPI:UniProtKB. | | | | | | | | | | GO:0006935; P:chemotaxis; TAS:ProtInc.::GO:0043089; P:positive regulation of Cdc42 GTPase activity; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IPI:UniProtKB.::GO:0006810; P:transport; IDA:UniProtKB. | 64 | Q9NR12 | 457 | PDLI7_HUMAN PDZ and LIM domain protein 7 OS=H... | 109 | 0.00000008 | 59.7 | 28 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:HPA. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0001503; P:ossification; IEA:UniProtKB-KW.::GO:0006898; P:receptor-mediated endocytosis; TAS:ProtInc. | 65 | A8DZE6 | 648 | WTIP_DANRE Wilms tumor protein 1-interacting ... | 162 | 0.000000000002 | 75.5 | 32 | 48 | GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0014032; P:neural crest cell development; ISS:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 66 | A9LS46 | 690 | WTIP_XENLA Wilms tumor protein 1-interacting ... | 162 | 0.000000000002 | 75.5 | 32 | 48 | GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003714; F:transcription corepressor activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0014032; P:neural crest cell development; IMP:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 67 | P53667 | 647 | LIMK1_HUMAN LIM domain kinase 1 OS=Homo sapie... | 92 | 0.00000003 | 61.6 | 33 | 49 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0043005; C:neuron projection; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IDA:BHF-UCL.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; TAS:Reactome.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051444; P:negative regulation of ubiquitin-protein ligase activity; IDA:BHF-UCL.::GO:0032233; P:positive regulation of actin filament bundle assembly; IDA:BHF-UCL.::GO:0045773; P:positive regulation of axon extension; ISS:UniProtKB.::GO:0007266; P:Rho protein signal transduction; TAS:ProtInc. | 68 | Q68EM7 | 881 | RHG17_HUMAN Rho GTPase-activating protein 17 ... | 213 | 0.000000000002 | 75.1 | 28 | 44 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 69 | Q6Y5D8 | 786 | RHG10_MOUSE Rho GTPase-activating protein 10 ... | 316 | 0.000000000002 | 75.1 | 26 | 43 | GO:0005829; C:cytosol; IMP:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; IPI:MGI.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; IMP:MGI.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 70 | Q9JKS4 | 723 | LDB3_MOUSE LIM domain-binding protein 3 OS=Mu... | 118 | 0.00000001 | 62.8 | 30 | 42 | GO:0005856; C:cytoskeleton; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IDA:MGI. | | | | | | | | | | GO:0005080; F:protein kinase C binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 71 | P15882 | 459 | CHIN_HUMAN N-chimaerin OS=Homo sapiens (Human... | 165 | 0.000000000002 | 73.9 | 32 | 50 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0050770; P:regulation of axonogenesis; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 72 | Q17R89 | 818 | RHG44_HUMAN Rho GTPase-activating protein 44 ... | 204 | 0.000000000003 | 75.1 | 28 | 45 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 73 | Q8N264 | 748 | RHG24_HUMAN Rho GTPase-activating protein 24 ... | 249 | 0.000000000003 | 74.7 | 29 | 47 | GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 74 | Q3UIA2 | 846 | RHG17_MOUSE Rho GTPase-activating protein 17 ... | 213 | 0.000000000003 | 74.3 | 27 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 75 | Q54FF4 | 734 | GACL_DICDI Rho GTPase-activating protein gacL... | 230 | 0.000000000003 | 74.3 | 30 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 76 | Q99N37 | 858 | RHG17_RAT Rho GTPase-activating protein 17 OS... | 213 | 0.000000000004 | 74.3 | 27 | 43 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005626; C:insoluble fraction; IDA:MGI.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007015; P:actin filament organization; IDA:MGI.::GO:0017156; P:calcium ion-dependent exocytosis; IDA:MGI.::GO:0007165; P:signal transduction; IEA:InterPro. | 77 | Q8N103 | 731 | TAGAP_HUMAN T-cell activation Rho GTPase-acti... | 266 | 0.000000000004 | 73.9 | 26 | 45 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 78 | Q6INU3 | 421 | PDLI7_XENLA PDZ and LIM domain protein 7 OS=X... | 117 | 0.00000004 | 60.5 | 29 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 79 | Q559A0 | 1164 | GACU_DICDI Rho GTPase-activating protein gacU... | 188 | 0.000000000005 | 74.3 | 30 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 80 | A1A4S6 | 786 | RHG10_HUMAN Rho GTPase-activating protein 10 ... | 326 | 0.000000000006 | 73.9 | 23 | 39 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 81 | P55194 | 601 | 3BP1_MOUSE SH3 domain-binding protein 1 OS=Mu... | 135 | 0.000000000006 | 73.6 | 35 | 50 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IPI:MGI. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 82 | Q17QN0 | 334 | CHIN_BOVIN N-chimaerin OS=Bos taurus (Bovine)... | 165 | 0.000000000006 | 72 | 33 | 49 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0050770; P:regulation of axonogenesis; ISS:UniProtKB. | 83 | A6NIX2 | 430 | WTIP_HUMAN Wilms tumor protein 1-interacting ... | 100 | 0.01 | 43.5 | 26 | 41 | GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0000932; C:cytoplasmic mRNA processing body; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0035195; P:gene silencing by miRNA; IMP:MGI.::GO:0035331; P:negative regulation of hippo signaling cascade; IDA:UniProtKB.::GO:2000637; P:positive regulation of gene silencing by miRNA; IMP:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0001666; P:response to hypoxia; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 84 | Q3SX40 | 424 | PDLI7_BOVIN PDZ and LIM domain protein 7 OS=B... | 117 | 0.0000003 | 57.8 | 29 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0001503; P:ossification; IEA:UniProtKB-KW. | 85 | P52757 | 468 | CHIO_HUMAN Beta-chimaerin OS=Homo sapiens (Hu... | 165 | 0.000000000007 | 72.8 | 28 | 48 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 86 | Q92502 | 1023 | STAR8_HUMAN StAR-related lipid transfer prote... | 277 | 0.000000000007 | 73.6 | 26 | 43 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 87 | P48059 | 325 | LIMS1_HUMAN LIM and senescent cell antigen-li... | 32 | 7.6 | 33.9 | 38 | 53 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0007569; P:cell aging; TAS:ProtInc.::GO:0034329; P:cell junction assembly; TAS:Reactome.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB. | 88 | A7MB27 | 530 | RHG36_BOVIN Rho GTPase-activating protein 36 ... | 182 | 0.000000000009 | 72.8 | 31 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 89 | Q99JW4 | 325 | LIMS1_MOUSE LIM and senescent cell antigen-li... | 32 | 8 | 33.9 | 38 | 53 | GO:0005925; C:focal adhesion; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016337; P:cell-cell adhesion; IMP:MGI.::GO:0007160; P:cell-matrix adhesion; IMP:MGI.::GO:0043009; P:chordate embryonic development; IMP:MGI.::GO:0007163; P:establishment or maintenance of cell polarity; IMP:MGI. | 90 | Q2KJ33 | 341 | LIMS2_BOVIN LIM and senescent cell antigen-li... | 57 | 1.9 | 35.8 | 32 | 49 | GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 91 | Q679P3 | 416 | PDLI7_CHICK PDZ and LIM domain protein 7 OS=G... | 117 | 0.00000003 | 60.8 | 30 | 50 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0001503; P:ossification; IEA:UniProtKB-KW. |
