| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q6P4F7 | 1023 | RHGBA_HUMAN Rho GTPase-activating protein 11A... | 221 | 0.000000000000001 | 85.9 | 29 | 49 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 32 | Q8C170 | 2542 | MYO9A_MOUSE Unconventional myosin-IXa OS=Mus ... | 221 | 0.000000000000004 | 84.7 | 31 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 33 | Q9Y3M8 | 1113 | STA13_HUMAN StAR-related lipid transfer prote... | 268 | 0.000000000000004 | 84 | 27 | 44 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005811; C:lipid particle; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 34 | O14639 | 778 | ABLM1_HUMAN Actin-binding LIM protein 1 OS=Ho... | 53 | 3.5 | 35.4 | 38 | 49 | GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; IEA:InterPro.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0007601; P:visual perception; TAS:ProtInc. | 35 | Q923Q2 | 1113 | STA13_MOUSE StAR-related lipid transfer prote... | 222 | 0.000000000000007 | 83.6 | 29 | 47 | GO:0005811; C:lipid particle; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro. | 36 | Q9Z1N3 | 2626 | MYO9A_RAT Unconventional myosin-IXa OS=Rattus... | 221 | 0.000000000000007 | 84 | 31 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 37 | Q54FG5 | 873 | GACJJ_DICDI Rho GTPase-activating protein gac... | 181 | 0.00000000000001 | 82.8 | 33 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 38 | B2RTY4 | 2548 | MYO9A_HUMAN Unconventional myosin-IXa OS=Homo... | 195 | 0.00000000000002 | 82.8 | 32 | 50 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0016461; C:unconventional myosin complex; NAS:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0007601; P:visual perception; TAS:ProtInc. | 39 | Q54NW4 | 553 | LIMB_DICDI LIM domain-containing protein B OS... | 61 | 0.038 | 41.6 | 38 | 49 | GO:0005938; C:cell cortex; IDA:dictyBase.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; ISS:dictyBase. | | | | | | | | | | GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0007155; P:cell adhesion; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0031154; P:culmination involved in sorocarp development; IMP:dictyBase. | 40 | Q9VTU3 | 476 | RG68F_DROME Rho GTPase-activating protein 68F... | 201 | 0.00000000000004 | 80.1 | 30 | 48 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; IDA:FlyBase. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro.::GO:0007370; P:ventral furrow formation; IMP:FlyBase. | 41 | Q3KRB8 | 267 | RHGBB_HUMAN Rho GTPase-activating protein 11B... | 181 | 0.00000000000004 | 77.4 | 31 | 49 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 42 | P11274 | 1271 | BCR_HUMAN Breakpoint cluster region protein O... | 203 | 0.00000000000006 | 80.5 | 27 | 45 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 43 | Q6PAJ1 | 1270 | BCR_MOUSE Breakpoint cluster region protein O... | 203 | 0.00000000000006 | 80.5 | 27 | 45 | GO:0005829; C:cytosol; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0030675; F:Rac GTPase activator activity; IGI:MGI.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IGI:MGI.::GO:0007420; P:brain development; IGI:MGI.::GO:0042472; P:inner ear morphogenesis; IGI:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0030336; P:negative regulation of cell migration; IGI:MGI.::GO:0050728; P:negative regulation of inflammatory response; IMP:MGI.::GO:0043314; P:negative regulation of neutrophil degranulation; IGI:MGI.::GO:0050885; P:neuromuscular process controlling balance; IGI:MGI.::GO:0050766; P:positive regulation of phagocytosis; IGI:MGI.::GO:0051726; P:regulation of cell cycle; IDA:MGI.::GO:0032496; P:response to lipopolysaccharide; IMP:MGI. | 44 | Q6H8Q1 | 611 | ABLM2_HUMAN Actin-binding LIM protein 2 OS=Ho... | 93 | 0.0009 | 47 | 24 | 43 | GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005737; C:cytoplasm; IDA:HPA.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; IEA:InterPro. | 45 | Q54TH9 | 721 | GACY_DICDI Rho GTPase-activating protein gacY... | 270 | 0.00000000000008 | 79.7 | 30 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 46 | Q9PT60 | 655 | RBP1A_XENLA RalA-binding protein 1-A OS=Xenop... | 184 | 0.00000000000008 | 79.7 | 32 | 52 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017160; F:Ral GTPase binding; IPI:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IMP:UniProtKB.::GO:0001702; P:gastrulation with mouth forming second; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IPI:UniProtKB. | 47 | Q55BI0 | 186 | Y6787_DICDI LIM domain-containing protein DDB... | 88 | 0.0008 | 45.1 | 30 | 43 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 48 | Q62172 | 648 | RBP1_MOUSE RalA-binding protein 1 OS=Mus musc... | 179 | 0.0000000000001 | 79 | 35 | 53 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0016020; C:membrane; ISS:UniProtKB. | | | | | | | | | | GO:0030675; F:Rac GTPase activator activity; IDA:UniProtKB.::GO:0017160; F:Ral GTPase binding; IPI:UniProtKB. | | | | | | | | | | GO:0043089; P:positive regulation of Cdc42 GTPase activity; IDA:UniProtKB.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 49 | Q8K031 | 1019 | STAR8_MOUSE StAR-related lipid transfer prote... | 277 | 0.0000000000001 | 79.3 | 27 | 43 | GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 50 | Q6ZUM4 | 889 | RHG27_HUMAN Rho GTPase-activating protein 27 ... | 210 | 0.0000000000002 | 78.2 | 26 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; ISS:HGNC.::GO:0017124; F:SH3 domain binding; ISS:HGNC. | | | | | | | | | | GO:0043089; P:positive regulation of Cdc42 GTPase activity; ISS:HGNC.::GO:0006898; P:receptor-mediated endocytosis; ISS:HGNC.::GO:0007165; P:signal transduction; IEA:InterPro. | 51 | Q7TQJ8 | 398 | WTIP_MOUSE Wilms tumor protein 1-interacting ... | 131 | 0.005 | 44.3 | 22 | 40 | GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0000932; C:cytoplasmic mRNA processing body; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0035331; P:negative regulation of hippo signaling cascade; ISS:UniProtKB.::GO:2000637; P:positive regulation of gene silencing by miRNA; ISS:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 52 | Q8K4G5 | 861 | ABLM1_MOUSE Actin-binding LIM protein 1 OS=Mu... | 56 | 0.94 | 37.4 | 39 | 50 | GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007411; P:axon guidance; IDA:MGI.::GO:0007010; P:cytoskeleton organization; IEA:InterPro.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI. | 53 | Q8BL65 | 612 | ABLM2_MOUSE Actin-binding LIM protein 2 OS=Mu... | 93 | 0.012 | 43.5 | 23 | 43 | GO:0030016; C:myofibril; IDA:MGI. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; IEA:InterPro.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI. | 54 | A2AB59 | 869 | RHG27_MOUSE Rho GTPase-activating protein 27 ... | 209 | 0.0000000000006 | 77 | 25 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; ISS:UniProtKB. | | | | | | | | | | GO:0043089; P:positive regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0006898; P:receptor-mediated endocytosis; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 55 | Q5SSM3 | 814 | RHG44_MOUSE Rho GTPase-activating protein 44 ... | 208 | 0.0000000000006 | 77 | 28 | 45 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 56 | Q6TLK4 | 869 | RHG27_RAT Rho GTPase-activating protein 27 OS... | 210 | 0.0000000000006 | 77 | 25 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; IDA:HGNC.::GO:0017124; F:SH3 domain binding; IDA:HGNC. | | | | | | | | | | GO:0043089; P:positive regulation of Cdc42 GTPase activity; IDA:HGNC.::GO:0006898; P:receptor-mediated endocytosis; IMP:HGNC.::GO:0007165; P:signal transduction; IEA:InterPro. | 57 | Q9Z1Z9 | 457 | PDLI7_RAT PDZ and LIM domain protein 7 OS=Rat... | 117 | 0.0000001 | 59.3 | 29 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0001503; P:ossification; IEA:UniProtKB-KW.::GO:0045669; P:positive regulation of osteoblast differentiation; IDA:RGD. | 58 | Q8QFP8 | 662 | LIMK1_CHICK LIM domain kinase 1 OS=Gallus gal... | 91 | 0.000000003 | 65.1 | 36 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030426; C:growth cone; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 59 | P34288 | 1605 | PAC1_CAEEL GTPase-activating protein pac-1 OS... | 196 | 0.000000000001 | 76.6 | 26 | 45 | GO:0030054; C:cell junction; IDA:WormBase.::GO:0005737; C:cytoplasm; NAS:UniProtKB. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; IDA:UniProtKB. | | | | | | | | | | GO:0008105; P:asymmetric protein localization; IMP:WormBase.::GO:0010470; P:regulation of gastrulation; IMP:WormBase.::GO:0007266; P:Rho protein signal transduction; IDA:UniProtKB. | 60 | O75112 | 727 | LDB3_HUMAN LIM domain-binding protein 3 OS=Ho... | 121 | 0.00000003 | 61.6 | 29 | 41 | GO:0005856; C:cytoskeleton; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 61 | Q6KC51 | 612 | ABLM2_RAT Actin-binding LIM protein 2 OS=Ratt... | 93 | 0.007 | 43.9 | 23 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; IEA:InterPro. |
