| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
271 | Q54XE8 | 576 | GACP_DICDI Rho GTPase-activating protein gacP... | 185 | 0.0000007 | 57 | 28 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 272 | Q9Z1Y4 | 480 | TRIP6_MOUSE Thyroid receptor-interacting prot... | 122 | 0.000009 | 53.1 | 27 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005149; F:interleukin-1 receptor binding; ISS:UniProtKB.::GO:0019900; F:kinase binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008588; P:release of cytoplasmic sequestered NF-kappaB; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 273 | Q54QF4 | 909 | MGP4_DICDI Mental retardation GTPase activati... | 190 | 0.0000007 | 57.4 | 24 | 47 | GO:0000331; C:contractile vacuole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 274 | Q6AYC5 | 482 | RHG15_RAT Rho GTPase-activating protein 15 OS... | 194 | 0.0000008 | 56.6 | 22 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 275 | Q15942 | 572 | ZYX_HUMAN Zyxin OS=Homo sapiens (Human). GN=Z... | 71 | 0.094 | 40.4 | 28 | 46 | GO:0005913; C:cell-cell adherens junction; IDA:MGI.::GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0001725; C:stress fiber; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; TAS:ProtInc.::GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:ProtInc. | 276 | Q640N3 | 1101 | RHG30_MOUSE Rho GTPase-activating protein 30 ... | 162 | 0.0000008 | 57.4 | 30 | 51 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 277 | Q174I2 | 916 | PRIC1_AEDAE Protein prickle OS=Aedes aegypti ... | 57 | 8.7 | 34.3 | 33 | 51 | GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009948; P:anterior/posterior axis specification; ISS:UniProtKB.::GO:0001736; P:establishment of planar polarity; ISS:UniProtKB. | 278 | Q9WTX7 | 284 | FHL5_MOUSE Four and a half LIM domains protei... | 70 | 10 | 33.5 | 26 | 43 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003713; F:transcription coactivator activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; TAS:MGI. | 279 | Q9H2C1 | 402 | LHX5_HUMAN LIM/homeobox protein Lhx5 OS=Homo ... | 77 | 0.016 | 42.7 | 25 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 280 | Q292U2 | 1353 | PRIC1_DROPS Protein prickle OS=Drosophila pse... | 57 | 6.5 | 34.7 | 32 | 51 | GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009948; P:anterior/posterior axis specification; ISS:UniProtKB.::GO:0001736; P:establishment of planar polarity; ISS:UniProtKB. | 281 | Q9C0H5 | 1083 | RHG39_HUMAN Rho GTPase-activating protein 39 ... | 259 | 0.0000009 | 57 | 27 | 42 | GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 282 | O70433 | 279 | FHL2_MOUSE Four and a half LIM domains protei... | 83 | 0.017 | 42 | 34 | 49 | GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0055014; P:atrial cardiac muscle cell development; IEP:BHF-UCL.::GO:0060347; P:heart trabecula formation; IEP:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0001649; P:osteoblast differentiation; IEP:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0055015; P:ventricular cardiac muscle cell development; IEP:BHF-UCL. | 283 | B2RQE8 | 841 | RHG42_MOUSE Rho GTPase-activating protein 42 ... | 124 | 0.000001 | 56.6 | 27 | 49 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 284 | Q3SX26 | 481 | TRIP6_BOVIN Thyroid receptor-interacting prot... | 122 | 0.00003 | 51.2 | 26 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005149; F:interleukin-1 receptor binding; ISS:UniProtKB.::GO:0019900; F:kinase binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008588; P:release of cytoplasmic sequestered NF-kappaB; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 285 | Q68EY3 | 331 | LHX9_XENLA LIM/homeobox protein Lhx9 OS=Xenop... | 91 | 0.022 | 42 | 24 | 45 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB. | 286 | Q15654 | 476 | TRIP6_HUMAN Thyroid receptor-interacting prot... | 125 | 0.00004 | 51.2 | 26 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005149; F:interleukin-1 receptor binding; IDA:UniProtKB.::GO:0019900; F:kinase binding; IPI:UniProtKB.::GO:0046966; F:thyroid hormone receptor binding; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0048041; P:focal adhesion assembly; NAS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008588; P:release of cytoplasmic sequestered NF-kappaB; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 287 | Q503U0 | 145 | LMO3_DANRE LIM domain only protein 3 OS=Danio... | 125 | 0.000001 | 53.5 | 26 | 44 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 288 | Q811M1 | 481 | RHG15_MOUSE Rho GTPase-activating protein 15 ... | 194 | 0.000001 | 56.2 | 22 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 289 | Q9DBZ9 | 737 | SYDE1_MOUSE Rho GTPase-activating protein SYD... | 217 | 0.000001 | 56.6 | 27 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB. | | | | | | | | | | GO:0032862; P:activation of Rho GTPase activity; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 290 | Q86IG9 | 566 | GACH_DICDI Rho GTPase-activating protein gacH... | 134 | 0.000001 | 56.2 | 29 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 291 | B7ZUL2 | 593 | LIMD1_XENTR LIM domain-containing protein 1 O... | 138 | 0.000001 | 56.2 | 28 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0014032; P:neural crest cell development; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 292 | Q292U5 | 795 | ESN_DROPS Protein espinas OS=Drosophila pseud... | 157 | 0.000001 | 56.2 | 28 | 41 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 293 | A2PZF9 | 379 | LHX9_GLARU LIM/homeobox protein Lhx9 OS=Gland... | 92 | 0.0008 | 46.6 | 27 | 48 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB. | 294 | Q7QJT4 | 923 | PRIC1_ANOGA Protein prickle OS=Anopheles gamb... | 57 | 6.5 | 34.7 | 33 | 51 | GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009948; P:anterior/posterior axis specification; ISS:UniProtKB.::GO:0001736; P:establishment of planar polarity; ISS:UniProtKB. | 295 | Q14192 | 279 | FHL2_HUMAN Four and a half LIM domains protei... | 134 | 6.3 | 33.9 | 22 | 40 | GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0050681; F:androgen receptor binding; NAS:UniProtKB.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0009725; P:response to hormone stimulus; IMP:BHF-UCL.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 296 | P61376 | 402 | LHX5_RAT LIM/homeobox protein Lhx5 OS=Rattus ... | 77 | 0.034 | 41.6 | 25 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 297 | P61375 | 402 | LHX5_MOUSE LIM/homeobox protein Lhx5 OS=Mus m... | 77 | 0.034 | 41.6 | 25 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0021846; P:cell proliferation in forebrain; IMP:MGI.::GO:0021702; P:cerebellar Purkinje cell differentiation; IGI:MGI.::GO:0021937; P:cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation; IGI:MGI.::GO:0021879; P:forebrain neuron differentiation; IMP:MGI.::GO:0021766; P:hippocampus development; IMP:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IGI:UniProtKB.::GO:0021527; P:spinal cord association neuron differentiation; IGI:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 298 | A5H447 | 663 | ZYX_XENLA Zyxin OS=Xenopus laevis (African cl... | 75 | 0.5 | 38.1 | 28 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0001725; C:stress fiber; ISS:UniProtKB. | | | | | | | | | | GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 299 | P36166 | 706 | PXL1_YEAST Paxillin-like protein 1 OS=Sacchar... | 122 | 0.000002 | 55.8 | 31 | 46 | GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0005737; C:cytoplasm; IDA:SGD.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD. | | | | | | | | | | GO:0005094; F:Rho GDP-dissociation inhibitor activity; IGI:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030011; P:maintenance of cell polarity; IMP:SGD.::GO:0035023; P:regulation of Rho protein signal transduction; IPI:SGD. | 300 | Q3E875 | 376 | RGAP1_ARATH Uncharacterized Rho GTPase-activa... | 191 | 0.000002 | 55.1 | 29 | 45 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 301 | Q55CK2 | 877 | MGP2_DICDI Mental retardation GTPase activati... | 253 | 0.000002 | 55.8 | 28 | 44 | GO:0000331; C:contractile vacuole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0033298; P:contractile vacuole organization; IGI:dictyBase.::GO:0006887; P:exocytosis; IGI:dictyBase.::GO:0051490; P:negative regulation of filopodium assembly; IMP:dictyBase.::GO:0042331; P:phototaxis; IGI:dictyBase.::GO:0051270; P:regulation of cellular component movement; IMP:dictyBase.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0030587; P:sorocarp development; IMP:dictyBase. |
