| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
181 | Q9BE31 | 847 | RHG12_MACFA Rho GTPase-activating protein 12 ... | 186 | 0.000000007 | 63.9 | 26 | 48 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 182 | Q91XD2 | 341 | LIMS2_MOUSE LIM and senescent cell antigen-li... | 98 | 2.5 | 35.4 | 28 | 42 | GO:0005925; C:focal adhesion; IDA:MGI. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 183 | Q5ZMM3 | 475 | RHG15_CHICK Rho GTPase-activating protein 15 ... | 194 | 0.000000009 | 62.8 | 23 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 184 | D2H9U0 | 547 | RHG36_AILME Rho GTPase-activating protein 36 ... | 176 | 0.00000001 | 62.8 | 30 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 185 | Q8C0D4 | 838 | RHG12_MOUSE Rho GTPase-activating protein 12 ... | 186 | 0.00000001 | 63.2 | 26 | 48 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 186 | G5E5X0 | 674 | LIMD1_BOVIN LIM domain-containing protein 1 O... | 122 | 0.000004 | 54.7 | 28 | 45 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0035331; P:negative regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0045668; P:negative regulation of osteoblast differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0002076; P:osteoblast development; ISS:UniProtKB.::GO:0016310; P:phosphorylation; ISS:UniProtKB.::GO:2000637; P:positive regulation of gene silencing by miRNA; ISS:UniProtKB.::GO:0001666; P:response to hypoxia; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 187 | Q9UBR4 | 397 | LHX3_HUMAN LIM/homeobox protein Lhx3 OS=Homo ... | 91 | 0.002 | 45.1 | 30 | 43 | GO:0005634; C:nucleus; TAS:ProtInc. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0048839; P:inner ear development; IEP:UniProtKB.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 188 | P53666 | 642 | LIMK2_CHICK LIM domain kinase 2 OS=Gallus gal... | 91 | 0.00005 | 51.2 | 30 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 189 | Q9UGP4 | 676 | LIMD1_HUMAN LIM domain-containing protein 1 O... | 122 | 0.000004 | 54.7 | 28 | 45 | GO:0000932; C:cytoplasmic mRNA processing body; IDA:MGI.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0016442; C:RNA-induced silencing complex; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:ProtInc. | | | | | | | | | | GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0033962; P:cytoplasmic mRNA processing body assembly; IMP:MGI.::GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0035195; P:gene silencing by miRNA; IMP:MGI.::GO:0007275; P:multicellular organismal development; TAS:ProtInc.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0035331; P:negative regulation of hippo signaling cascade; IDA:UniProtKB.::GO:0045668; P:negative regulation of osteoblast differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0002076; P:osteoblast development; ISS:UniProtKB.::GO:0016310; P:phosphorylation; IDA:UniProtKB.::GO:2000637; P:positive regulation of gene silencing by miRNA; IMP:UniProtKB.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0001666; P:response to hypoxia; IDA:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 190 | Q7Z4I7 | 341 | LIMS2_HUMAN LIM and senescent cell antigen-li... | 98 | 1.1 | 36.6 | 27 | 42 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0034329; P:cell junction assembly; TAS:Reactome. | 191 | Q13017 | 1502 | RHG05_HUMAN Rho GTPase-activating protein 5 O... | 178 | 0.00000002 | 62.8 | 27 | 43 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0005100; F:Rho GTPase activator activity; TAS:ProtInc.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB. | | | | | | | | | | GO:0007155; P:cell adhesion; TAS:ProtInc.::GO:0007266; P:Rho protein signal transduction; TAS:ProtInc. | 192 | A4IF90 | 471 | RHG15_BOVIN Rho GTPase-activating protein 15 ... | 194 | 0.00000002 | 62 | 24 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 193 | P97447 | 280 | FHL1_MOUSE Four and a half LIM domains protei... | 58 | 1.9 | 35.8 | 28 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 194 | P53671 | 638 | LIMK2_HUMAN LIM domain kinase 2 OS=Homo sapie... | 91 | 0.002 | 46.2 | 30 | 46 | GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; TAS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0042325; P:regulation of phosphorylation; IEA:InterPro. | 195 | Q7Z6I6 | 1101 | RHG30_HUMAN Rho GTPase-activating protein 30 ... | 222 | 0.00000002 | 62.4 | 27 | 47 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 196 | Q8BRH3 | 494 | RHG19_MOUSE Rho GTPase-activating protein 19 ... | 149 | 0.00000002 | 61.6 | 31 | 51 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 197 | Q9P107 | 970 | GMIP_HUMAN GEM-interacting protein OS=Homo sa... | 164 | 0.00000002 | 62.4 | 28 | 48 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:HGNC.::GO:0005100; F:Rho GTPase activator activity; IDA:HGNC. | | | | | | | | | | GO:0034259; P:negative regulation of Rho GTPase activity; IDA:BHF-UCL.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 198 | Q5F464 | 604 | LPP_CHICK Lipoma-preferred partner homolog OS... | 39 | 7.9 | 34.3 | 33 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 199 | O97581 | 383 | LHX3_PIG LIM/homeobox protein Lhx3 OS=Sus scr... | 91 | 0.007 | 43.9 | 29 | 43 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; NAS:UniProtKB. | | | | | | | | | | GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 200 | Q54XT6 | 783 | GACR_DICDI Rho GTPase-activating protein gacR... | 190 | 0.00000002 | 62 | 27 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 201 | Q9WUH4 | 280 | FHL1_RAT Four and a half LIM domains protein ... | 58 | 1.9 | 35.8 | 28 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 202 | P50481 | 400 | LHX3_MOUSE LIM/homeobox protein Lhx3 OS=Mus m... | 91 | 0.015 | 42.7 | 27 | 42 | GO:0005667; C:transcription factor complex; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0000988; F:protein binding transcription factor activity; IPI:MGI.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0021526; P:medial motor column neuron differentiation; IGI:MGI.::GO:0008045; P:motor axon guidance; IGI:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.::GO:0021983; P:pituitary gland development; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0021527; P:spinal cord association neuron differentiation; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0021521; P:ventral spinal cord interneuron specification; IDA:MGI. | 203 | P46941 | 837 | TG325_CAEEL WW domain-containing protein tag-... | 237 | 0.00000002 | 62 | 22 | 43 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 204 | Q9Z0S2 | 406 | LHX2_MOUSE LIM/homeobox protein Lhx2 OS=Mus m... | 92 | 0.005 | 44.3 | 26 | 49 | GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0000988; F:protein binding transcription factor activity; IPI:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007411; P:axon guidance; IMP:MGI.::GO:0009953; P:dorsal/ventral pattern formation; IMP:MGI.::GO:0007498; P:mesoderm development; IMP:MGI.::GO:2000678; P:negative regulation of transcription regulatory region DNA binding; IGI:MGI.::GO:0001843; P:neural tube closure; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0021978; P:telencephalon regionalization; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 205 | P50458 | 406 | LHX2_HUMAN LIM/homeobox protein Lhx2 OS=Homo ... | 92 | 0.006 | 43.9 | 26 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 206 | Q6ZW31 | 735 | SYDE1_HUMAN Rho GTPase-activating protein SYD... | 184 | 0.00000003 | 61.6 | 29 | 47 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB. | | | | | | | | | | GO:0032862; P:activation of Rho GTPase activity; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 207 | Q9CXP4 | 425 | RHG08_MOUSE Rho GTPase-activating protein 8 O... | 188 | 0.00000003 | 60.8 | 28 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 208 | P53776 | 390 | LHX4_MOUSE LIM/homeobox protein Lhx4 OS=Mus m... | 90 | 0.003 | 44.7 | 28 | 42 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IMP:MGI.::GO:0021526; P:medial motor column neuron differentiation; IGI:MGI.::GO:0008045; P:motor axon guidance; IGI:MGI.::GO:0009887; P:organ morphogenesis; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 209 | Q53QZ3 | 475 | RHG15_HUMAN Rho GTPase-activating protein 15 ... | 194 | 0.00000003 | 61.2 | 23 | 46 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; IDA:MGI. | | | | | | | | | | GO:0008360; P:regulation of cell shape; IDA:MGI.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 210 | Q969G2 | 390 | LHX4_HUMAN LIM/homeobox protein Lhx4 OS=Homo ... | 90 | 0.004 | 44.7 | 28 | 42 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 211 | Q8IWW6 | 846 | RHG12_HUMAN Rho GTPase-activating protein 12 ... | 210 | 0.00000003 | 61.6 | 23 | 47 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. |
